François Lanza Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S 1255, FMTS, F-67065 Strasbourg, France Biography Publications Institution JoVE Articles François Lanza has not added a biography. If you are François Lanza and would like to personalize this page please email our Author Liaison for assistance. Publications Correction: An Essential Role for α4A-tubulin in Platelet Biogenesis Life Science Alliance. Aug, 2021 | Pubmed ID: 34155037 Differential Regulation of the Platelet GPIb-IX Complex by Anti-GPIbβ Antibodies Journal of Thrombosis and Haemostasis : JTH. Apr, 2021 | Pubmed ID: 33915031 CDX2 Regulates ACE Expression in Blood Development and Leukemia Cells Blood Advances. 04, 2021 | Pubmed ID: 33843985 Cytoskeletal-based Mechanisms Differently Regulate and Proplatelet Formation Haematologica. May, 2021 | Pubmed ID: 32327502 Desialylation of -glycans on Glycoprotein Ibα Drives Receptor Signaling and Platelet Clearance Haematologica. 01, 2021 | Pubmed ID: 31974202 Blood Platelet Formation at a Glance Journal of Cell Science. 10, 2020 | Pubmed ID: 33127839 Shear Rate Gradients Promote a Bi-phasic Thrombus Formation on Weak Adhesive Proteins, Such As Fibrinogen in a VWF-dependent Manner Haematologica. 10, 2020 | Pubmed ID: 33054087 Megakaryocytes Use in Vivo Podosome-like Structures Working Collectively to Penetrate the Endothelial Barrier of Bone Marrow Sinusoids Journal of Thrombosis and Haemostasis : JTH. 11, 2020 | Pubmed ID: 32702204 Pharmacological Blockade of Glycoprotein VI Promotes Thrombus Disaggregation in the Absence of Thrombin Arteriosclerosis, Thrombosis, and Vascular Biology. 09, 2020 | Pubmed ID: 32698684 Marginal Band Microtubules Are Acetylated by αTAT1 Platelets. May, 2020 | Pubmed ID: 32362199 High Prevalence of the Natural Asn89Asp Mutation in the GP1BB Gene Associated with Bernard-Soulier Syndrome in French Patients from the Genetic Isolate of Reunion Island British Journal of Haematology. 05, 2020 | Pubmed ID: 31997307 Combined Deficiency of RAB32 and RAB38 in the Mouse Mimics Hermansky-Pudlak Syndrome and Critically Impairs Thrombosis Blood Advances. 08, 2019 | Pubmed ID: 31399401 A Novel Missense Mutation in a Leucine-rich Repeat of GPIbα in a Bernard-Soulier Variant Reduces Shear-dependent Adherence on Von Willebrand Factor British Journal of Haematology. 09, 2019 | Pubmed ID: 31257572 An Essential Role for α4A-tubulin in Platelet Biogenesis Life Science Alliance. 02, 2019 | Pubmed ID: 30760556 TUBB1 Mutations Cause Thyroid Dysgenesis Associated with Abnormal Platelet Physiology EMBO Molecular Medicine. 12, 2018 | Pubmed ID: 30446499 On the Way to Platelet Production Frontiers in Medicine. 2018 | Pubmed ID: 30211166 On the Way to in Vitro Platelet Production Transfusion Clinique Et Biologique : Journal De La Societe Francaise De Transfusion Sanguine. Sep, 2018 | Pubmed ID: 30150135 Imaging Thrombosis with Tc-labeled RAM.1-antibody in Vivo Nuclear Medicine and Biology. 06, 2018 | Pubmed ID: 29625391 A Unique Microenvironment in the Developing Liver Supports the Expansion of Megakaryocyte Progenitors Blood Advances. Sep, 2017 | Pubmed ID: 29296832 Dual Role of IL-21 in Megakaryopoiesis and Platelet Homeostasis Haematologica. 04, 2017 | Pubmed ID: 28057742 A Novel Platelet-type Von Willebrand Disease Mutation (GP1BA P.Met255Ile) Associated with Type 2B "Malmö/New York" Von Willebrand Disease Thrombosis and Haemostasis. Nov, 2016 | Pubmed ID: 27683759 Platelet Clearance Via Shear-induced Unfolding of a Membrane Mechanoreceptor Nature Communications. Sep, 2016 | Pubmed ID: 27670775 Importance of Environmental Stiffness for Megakaryocyte Differentiation and Proplatelet Formation Blood. 10, 2016 | Pubmed ID: 27503502 Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL PloS One. 2016 | Pubmed ID: 27010197 Time-Dependent Decay of MRNA and Ribosomal RNA During Platelet Aging and Its Correlation with Translation Activity PloS One. 2016 | Pubmed ID: 26808079 A New Form of Macrothrombocytopenia Induced by a Germ-line Mutation in the PRKACG Gene Blood. Oct, 2014 | Pubmed ID: 25061177 Biogenesis of the Demarcation Membrane System (DMS) in Megakaryocytes Blood. Feb, 2014 | Pubmed ID: 24152908 Integrin α6β1 is the Main Receptor for Vascular Laminins and Plays a Role in Platelet Adhesion, Activation, and Arterial Thrombosis Circulation. Jul, 2013 | Pubmed ID: 23797810 A Central Role of GPIb-IX in the Procoagulant Function of Platelets That is Independent of the 45-kDa GPIbalpha N-terminal Extracellular Domain Blood. Aug, 2010 | Pubmed ID: 20457869 Intrinsic Impaired Proplatelet Formation and Microtubule Coil Assembly of Megakaryocytes in a Mouse Model of Bernard-Soulier Syndrome Haematologica. Jun, 2009 | Pubmed ID: 19377075 In Vitro and In Vivo Methods to Explore Megakaryopoiesis François Lanza1, Christian Gachet1, Anita Eckly1 1Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S 1255, FMTS, F-67065 Strasbourg, France JoVE 63286 Editorial In Situ Exploration of Murine Megakaryopoiesis using Transmission Electron Microscopy Cyril Scandola1, François Lanza1, Christian Gachet1, Anita Eckly1 1Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S 1255, FMTS JoVE 62494 Biology Megakaryocyte Culture in 3D Methylcellulose-Based Hydrogel to Improve Cell Maturation and Study the Impact of Stiffness and Confinement Julie Boscher1, Christian Gachet1, François Lanza1, Catherine Léon1 1Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S 1255, FMTS JoVE 62511 Biology In Vivo Two-photon Imaging of Megakaryocytes and Proplatelets in the Mouse Skull Bone Marrow Alicia Bornert1, Fabien Pertuy1, François Lanza1, Christian Gachet1, Catherine Léon1 1INSERM, EFS Grand Est, Université de Strasbourg JoVE 62515 Biology Proplatelet Formation Dynamics of Mouse Fresh Bone Marrow Explants Inès Guinard1, François Lanza1, Christian Gachet1, Catherine Léon1, Anita Eckly1 1Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S 1255, FMTS JoVE 62501 Biology Leukodepletion Filters-Derived CD34+ Cells As a Cell Source to Study Megakaryocyte Differentiation and Platelet Formation Anaïs Pongerard1, Lea Mallo1, Christian Gachet1, Henri de La Salle1, François Lanza1, Catherine Strassel1 1BPPS UMR-S 1255, FMTS, Université de Strasbourg, INSERM, EFS Grand Est JoVE 62499 Biology Isolation of Mouse Megakaryocyte Progenitors Quentin Kimmerlin1, Manuela Tavian2, Christian Gachet1, François Lanza1, Nathalie Brouard1 1Université de Strasbourg, INSERM UMR S1255, EFS Grand-EST, 2UMR-S1113 –IRFAC, Université de Strasbourg JoVE 62498 Biology
In Vitro and In Vivo Methods to Explore Megakaryopoiesis François Lanza1, Christian Gachet1, Anita Eckly1 1Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S 1255, FMTS, F-67065 Strasbourg, France JoVE 63286 Editorial
In Situ Exploration of Murine Megakaryopoiesis using Transmission Electron Microscopy Cyril Scandola1, François Lanza1, Christian Gachet1, Anita Eckly1 1Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S 1255, FMTS JoVE 62494 Biology
Megakaryocyte Culture in 3D Methylcellulose-Based Hydrogel to Improve Cell Maturation and Study the Impact of Stiffness and Confinement Julie Boscher1, Christian Gachet1, François Lanza1, Catherine Léon1 1Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S 1255, FMTS JoVE 62511 Biology
In Vivo Two-photon Imaging of Megakaryocytes and Proplatelets in the Mouse Skull Bone Marrow Alicia Bornert1, Fabien Pertuy1, François Lanza1, Christian Gachet1, Catherine Léon1 1INSERM, EFS Grand Est, Université de Strasbourg JoVE 62515 Biology
Proplatelet Formation Dynamics of Mouse Fresh Bone Marrow Explants Inès Guinard1, François Lanza1, Christian Gachet1, Catherine Léon1, Anita Eckly1 1Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S 1255, FMTS JoVE 62501 Biology
Leukodepletion Filters-Derived CD34+ Cells As a Cell Source to Study Megakaryocyte Differentiation and Platelet Formation Anaïs Pongerard1, Lea Mallo1, Christian Gachet1, Henri de La Salle1, François Lanza1, Catherine Strassel1 1BPPS UMR-S 1255, FMTS, Université de Strasbourg, INSERM, EFS Grand Est JoVE 62499 Biology
Isolation of Mouse Megakaryocyte Progenitors Quentin Kimmerlin1, Manuela Tavian2, Christian Gachet1, François Lanza1, Nathalie Brouard1 1Université de Strasbourg, INSERM UMR S1255, EFS Grand-EST, 2UMR-S1113 –IRFAC, Université de Strasbourg JoVE 62498 Biology
