Francisco Fernandez-Lima

Publications

• Top/Middle-Down Characterization of α-Synuclein Glycoforms
  Analytical Chemistry. Dec, 2023  |   Pubmed ID: 38047498
• HIV-1 and Opiates Modulate MiRNA Profiles in Extracellular Vesicles
  Frontiers in Immunology. 2023  |   Pubmed ID: 38022533
• Effects of Mating on Female Reproductive Physiology in the Insect Model, Rhodnius Prolixus, a Vector of the Causative Parasite of Chagas Disease
  PLoS Neglected Tropical Diseases. Sep, 2023  |   Pubmed ID: 37729234
• Integration of Trapped Ion Mobility Spectrometry and Ultraviolet Photodissociation in a Quadrupolar Ion Trap Mass Spectrometer
  Analytical Chemistry. Jun, 2023  |   Pubmed ID: 37220214
• Anticancer Drug Doxorubicin Spontaneously Reacts with GTP and DGTP
  Chemical Research in Toxicology. Apr, 2023  |   Pubmed ID: 37000908
• Distinct Mechanism of Tb and Eu Binding to NCS1
  Physical Chemistry Chemical Physics : PCCP. Mar, 2023  |   Pubmed ID: 36938969
• Description of Dissolved Organic Matter Transformational Networks at the Molecular Level
  Environmental Science & Technology. Feb, 2023  |   Pubmed ID: 36724500
• Submicron 3-D Mass Spectrometry Imaging Reveals an Asymmetric Molecular Distribution on Chemotaxing Cells
  F1000Research. 2022  |   Pubmed ID: 36845326
• Crosstalk Between Nutrition, Insulin, Juvenile Hormone, and Ecdysteroid Signaling in the Classical Insect Model,
  International Journal of Molecular Sciences. Dec, 2022  |   Pubmed ID: 36613451
• Genetics Tools for Corpora Allata Specific Gene Expression in Aedes Aegypti Mosquitoes
  Scientific Reports. Nov, 2022  |   Pubmed ID: 36443489
• Large-Scale Interlaboratory DI-FT-ICR MS Comparability Study Employing Various Systems
  Journal of the American Society for Mass Spectrometry. Dec, 2022  |   Pubmed ID: 36371691
• Top-"Double-Down" Mass Spectrometry of Histone H4 Proteoforms: Tandem Ultraviolet-Photon and Mobility/Mass-Selected Electron Capture Dissociations
  Analytical Chemistry. Nov, 2022  |   Pubmed ID: 36282112
• Globin X: A Highly Stable Intrinsically Hexacoordinate Globin
  Journal of Inorganic Biochemistry. Nov, 2022  |   Pubmed ID: 36058051
• Exploring the Conformations and Binding Location of HMGA2·DNA Complexes Using Ion Mobility Spectrometry and 193 Nm Ultraviolet Photodissociation Mass Spectrometry
  Journal of the American Society for Mass Spectrometry. Jul, 2022  |   Pubmed ID: 35687872
• Exploring the Conformational and Binding Dynamics of HMGA2·DNA Complexes Using Trapped Ion Mobility Spectrometry-Mass Spectrometry
  Journal of the American Society for Mass Spectrometry. Jul, 2022  |   Pubmed ID: 35687119
• Trapped Ion Mobility Spectrometry, Ultraviolet Photodissociation, and Time-of-Flight Mass Spectrometry for Gas-Phase Peptide Isobars/Isomers/Conformers Discrimination
  Journal of the American Society for Mass Spectrometry. Jul, 2022  |   Pubmed ID: 35658468
• Nanomolar Affinity of EF-hands in Neuronal Calcium Sensor 1 for Bivalent Cations Pb2+, Mn2+, and Hg2
  Metallomics : Integrated Biometal Science. Jul, 2022  |   Pubmed ID: 35657675
• Coupling Stable Isotope Labeling and Liquid Chromatography-Trapped Ion Mobility Spectrometry-Time-of-Flight-Tandem Mass Spectrometry for Mosquito Ovarian Lipid Studies
  Analytical Chemistry. Apr, 2022  |   Pubmed ID: 35420029
• Spatially Resolved Neuropeptide Characterization from Neuropathological Formalin-Fixed, Paraffin-Embedded Tissue Sections by a Combination of Imaging MALDI FT-ICR Mass Spectrometry Histochemistry and Liquid Extraction Surface Analysis-Trapped Ion Mobility Spectrometry-Tandem Mass Spectrometry
  Journal of the American Society for Mass Spectrometry. Apr, 2022  |   Pubmed ID: 35258288
• AT-hook Peptides Bind the Major and Minor Groove of AT-rich DNA Duplexes
  Nucleic Acids Research. Mar, 2022  |   Pubmed ID: 35212375
• Sexual Dimorphism of Diapause Regulation in the Hemipteran Bug Pyrrhocoris Apterus
  Insect Biochemistry and Molecular Biology. Mar, 2022  |   Pubmed ID: 35007710
• Unsupervised Structural Classification of Dissolved Organic Matter Based on Fragmentation Pathways
  Environmental Science & Technology. Jan, 2022  |   Pubmed ID: 34981937
• Structural Characterization of Human Histone H4.1 by Tandem Nonlinear and Linear Ion Mobility Spectrometry Complemented with Molecular Dynamics Simulations
  ACS Omega. Nov, 2021  |   Pubmed ID: 34778628
• Substrate Sequence Controls Regioselectivity of Lanthionine Formation by ProcM
  Journal of the American Chemical Society. Nov, 2021  |   Pubmed ID: 34724611
• Effective Discrimination of Gas-phase Peptide Conformers Using TIMS-ECD-ToF MS/MS
  Analytical Methods : Advancing Methods and Applications. Nov, 2021  |   Pubmed ID: 34698320
• Epoxidation of Juvenile Hormone Was a Key Innovation Improving Insect Reproductive Fitness
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2021  |   Pubmed ID: 34697248
• A Bifunctional Leader Peptidase/ABC Transporter Protein Is Involved in the Maturation of the Lasso Peptide Cochonodin I from
  Journal of Natural Products. Oct, 2021  |   Pubmed ID: 34597519
• Author Correction: Following De Novo Triglyceride Dynamics in Ovaries of Aedes Aegypti During the Previtellogenic Stage
  Scientific Reports. Aug, 2021  |   Pubmed ID: 34354221
• Proteoform Differentiation Using Tandem Trapped Ion Mobility, Electron Capture Dissociation, and ToF Mass Spectrometry
  Analytical Chemistry. Jul, 2021  |   Pubmed ID: 34170114
• Exploring Structural Signatures of the Lanthipeptide Prochlorosin 2.8 Using Tandem Mass Spectrometry and Trapped Ion Mobility-mass Spectrometry
  Analytical and Bioanalytical Chemistry. Aug, 2021  |   Pubmed ID: 34105020
• Structural Heterogeneity of Human Histone H2A.1
  The Journal of Physical Chemistry. B. May, 2021  |   Pubmed ID: 33974801
• Following De Novo Triglyceride Dynamics in Ovaries of Aedes Aegypti During the Previtellogenic Stage
  Scientific Reports. May, 2021  |   Pubmed ID: 33953286
• Comprehensive Screening of Polycyclic Aromatic Hydrocarbons and Similar Compounds Using GC-APLI-TIMS-TOFMS/GC-EI-MS
  Analytical Chemistry. Apr, 2021  |   Pubmed ID: 33835784
• Structural Insights from Tandem Mass Spectrometry, Ion Mobility-Mass Spectrometry, and Infrared/Ultraviolet Spectroscopy on Sphingonodin I: Lasso Vs Branched-Cyclic Topoisomers
  Journal of the American Society for Mass Spectrometry. Apr, 2021  |   Pubmed ID: 33765377
• Trapped Ion Mobility Spectrometry of Native Macromolecular Assemblies
  Analytical Chemistry. Feb, 2021  |   Pubmed ID: 33492949
• Salt Bridges Govern the Structural Heterogeneity of Heme Protein Interactions and Porphyrin Networks: Microperoxidase-11
  RSC Advances. Sep, 2020  |   Pubmed ID: 35519052
• Identification of HMGA2 Inhibitors by AlphaScreen-based Ultra-high-throughput Screening Assays
  Scientific Reports. Nov, 2020  |   Pubmed ID: 33139812
• Mapping Chemotherapeutic Drug Distribution in Cancer Cell Spheroids Using 2D-TOF-SIMS and LESA-TIMS-MS
  The Analyst. Oct, 2020  |   Pubmed ID: 32966375
• Following Structural Changes by Thermal Denaturation Using Trapped Ion Mobility Spectrometry-Mass Spectrometry
  The Journal of Physical Chemistry. B. Jul, 2020  |   Pubmed ID: 32560586
• Physiologically Relevant Fluid-Induced Oscillatory Shear Stress Stimulation of Mesenchymal Stem Cells Enhances the Engineered Valve Matrix Phenotype
  Frontiers in Cardiovascular Medicine. 2020  |   Pubmed ID: 32509802
• LESA Cyclic Ion Mobility Mass Spectrometry of Intact Proteins from Thin Tissue Sections
  Analytical Chemistry. May, 2020  |   Pubmed ID: 32271006
• The Juvenile Hormone Described in Rhodnius Prolixus by Wigglesworth is Juvenile Hormone III Skipped Bisepoxide
  Scientific Reports. Feb, 2020  |   Pubmed ID: 32080221
• Multimodal, in Situ Imaging of Ex Vivo Human Skin Reveals Decrease of Cholesterol Sulfate in the Neoepithelium During Acute Wound Healing
  Analytical Chemistry. Jan, 2020  |   Pubmed ID: 31789498
• Common Structural Features Facilitate the Simultaneous Identification and Quantification of the Five Most Common Juvenile Hormones by Liquid Chromatography-tandem Mass Spectrometry
  Insect Biochemistry and Molecular Biology. Jan, 2020  |   Pubmed ID: 31760138
• Three Dimensional Secondary Ion Mass Spectrometry Imaging (3D-SIMS) of Ovarian Follicles
  Journal of Analytical Atomic Spectrometry. May, 2019  |   Pubmed ID: 31680712
• Dynamics of the E. coli β-Clamp Dimer Interface and Its Influence on DNA Loading
  Biophysical Journal. Aug, 2019  |   Pubmed ID: 31349986
• Exploring the Conformational Space of Growth-Hormone-Releasing Hormone Analogues Using Dopant Assisted Trapped Ion Mobility Spectrometry-Mass Spectrometry
  The Journal of Physical Chemistry. B. Jul, 2019  |   Pubmed ID: 31299151
• Inhibition of Juvenile Hormone Synthesis in Mosquitoes by the Methylation Inhibitor 3-deazaneplanocin A (DZNep)
  Insect Biochemistry and Molecular Biology. Oct, 2019  |   Pubmed ID: 31265905
• Understanding the Structural Complexity of Dissolved Organic Matter: Isomeric Diversity
  Faraday Discussions. Aug, 2019  |   Pubmed ID: 31134248
• Effective Liquid Chromatography-Trapped Ion Mobility Spectrometry-Mass Spectrometry Separation of Isomeric Lipid Species
  Analytical Chemistry. Apr, 2019  |   Pubmed ID: 30896930
• Microheterogeneity of Topoisomerase IA/IB and Their DNA-Bound States
  ACS Omega. Feb, 2019  |   Pubmed ID: 30842985
• Evidence of Cis/Trans-Isomerization at Pro7/Pro16 in the Lasso Peptide Microcin J25
  Journal of the American Society for Mass Spectrometry. Jun, 2019  |   Pubmed ID: 30834511
• Measuring the Integrity of Gas-Phase Conformers of Sodiated 25-Hydroxyvitamin D3 by Drift Tube, Traveling Wave, Trapped, and High-Field Asymmetric Ion Mobility
  Analytical Chemistry. Mar, 2019  |   Pubmed ID: 30807105
• Juvenile Hormone Controls Ovarian Development in Female Anopheles Albimanus Mosquitoes
  Scientific Reports. Feb, 2019  |   Pubmed ID: 30765796
• Recommendations for Reporting Ion Mobility Mass Spectrometry Measurements
  Mass Spectrometry Reviews. 05, 2019  |   Pubmed ID: 30707468
• Structural Signatures of the Class III Lasso Peptide BI-32169 and the Branched-cyclic Topoisomers Using Trapped Ion Mobility Spectrometry-mass Spectrometry and Tandem Mass Spectrometry
  Analytical and Bioanalytical Chemistry. Sep, 2019  |   Pubmed ID: 30707269
• Single-stranded DNA Structural Diversity: TAGGGT from Monomers to Dimers to Tetramer Formation
  Rapid Communications in Mass Spectrometry : RCM. Jul, 2019  |   Pubmed ID: 30506977
• The Effects of Solution Additives and Gas-phase Modifiers on the Molecular Environment and Conformational Space of Common Heme Proteins
  Rapid Communications in Mass Spectrometry : RCM. Mar, 2019  |   Pubmed ID: 30421840
• Structural Motif Descriptors As a Way To Elucidate the Agonistic or Antagonistic Activity of Growth Hormone-Releasing Hormone Peptide Analogues
  ACS Omega. Jul, 2018  |   Pubmed ID: 31458901
• Peptide Sequence Influence on the Conformational Dynamics and DNA Binding of the Intrinsically Disordered AT-Hook 3 Peptide
  Scientific Reports. Jul, 2018  |   Pubmed ID: 30018295
• Discovery and Targeted Monitoring of Polychlorinated Biphenyl Metabolites in Blood Plasma Using LC-TIMS-TOF MS
  International Journal of Mass Spectrometry. Apr, 2018  |   Pubmed ID: 29915519
• Coupling Trapped Ion Mobility Spectrometry to Mass Spectrometry: Trapped Ion Mobility Spectrometry-time-of-flight Mass Spectrometry Versus Trapped Ion Mobility Spectrometry-Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
  Rapid Communications in Mass Spectrometry : RCM. Aug, 2018  |   Pubmed ID: 29756663
• Biochemical Basis of Topoisomerase I Relaxation Activity Reduction by Nonenzymatic Lysine Acetylation
  International Journal of Molecular Sciences. May, 2018  |   Pubmed ID: 29751635
• Metal Ions Induced Secondary Structure Rearrangements: Mechanically Interlocked Lasso Vs. Unthreaded Branched-cyclic Topoisomers
  The Analyst. May, 2018  |   Pubmed ID: 29721555
• Identification of Lasso Peptide Topologies Using Native Nanoelectrospray Ionization-Trapped Ion Mobility Spectrometry-Mass Spectrometry
  Analytical Chemistry. Apr, 2018  |   Pubmed ID: 29579382
• Analysis of Isomeric Opioids in Urine Using LC-TIMS-TOF MS
  Talanta. Jun, 2018  |   Pubmed ID: 29567161
• JH Biosynthesis and Hemolymph Titers in Adult Male Aedes Aegypti Mosquitoes
  Insect Biochemistry and Molecular Biology. Apr, 2018  |   Pubmed ID: 29526769
• Insights from Ion Mobility-mass Spectrometry, Infrared Spectroscopy, and Molecular Dynamics Simulations on Nicotinamide Adenine Dinucleotide Structural Dynamics: NADvs. NADH
  Physical Chemistry Chemical Physics : PCCP. Mar, 2018  |   Pubmed ID: 29473073
• Increasing Analytical Separation and Duty Cycle with Nonlinear Analytical Mobility Scan Functions in TIMS-FT-ICR MS
  Analytical Chemistry. Feb, 2018  |   Pubmed ID: 29376337
• Linear and Differential Ion Mobility Separations of Middle-Down Proteoforms
  Analytical Chemistry. Feb, 2018  |   Pubmed ID: 29359922
• Towards Discovery and Targeted Peptide Biomarker Detection Using NanoESI-TIMS-TOF MS
  Journal of the American Society for Mass Spectrometry. May, 2018  |   Pubmed ID: 28889248
• Publisher Correction: Novel Detection of Post-translational Modifications in Human Monocyte-derived Dendritic Cells After Chronic Alcohol Exposure: Role of Inflammation Regulator H4K12ac
  Scientific Reports. Nov, 2017  |   Pubmed ID: 29162895
• Fast and Effective Ion Mobility-Mass Spectrometry Separation of D-Amino-Acid-Containing Peptides
  Analytical Chemistry. 11, 2017  |   Pubmed ID: 28982001
• Novel Detection of Post-translational Modifications in Human Monocyte-derived Dendritic Cells After Chronic Alcohol Exposure: Role of Inflammation Regulator H4K12ac
  Scientific Reports. Sep, 2017  |   Pubmed ID: 28894190
• Characterization of Intramolecular Interactions of Cytochrome C Using Hydrogen-Deuterium Exchange-Trapped Ion Mobility Spectrometry-Mass Spectrometry and Molecular Dynamics
  Analytical Chemistry. Sep, 2017  |   Pubmed ID: 28742962
• Analysis of Photoirradiated Water Accommodated Fractions of Crude Oils Using Tandem TIMS and FT-ICR MS
  Environmental Science & Technology. Jun, 2017  |   Pubmed ID: 28457132
• Towards the Analysis of High Molecular Weight Proteins and Protein Complexes Using TIMS-MS
  International Journal for Ion Mobility Spectrometry : Official Publication of the International Society for Ion Mobility Spectrometry. Sep, 2016  |   Pubmed ID: 27818614
• Structures of the Kinetically Trapped I-motif DNA Intermediates
  Physical Chemistry Chemical Physics : PCCP. Sep, 2016  |   Pubmed ID: 27711445
• Lipid Specific Molecular Ion Emission As a Function of the Primary Ion Characteristics in TOF-SIMS
  Journal of Vacuum Science and Technology. B, Nanotechnology & Microelectronics : Materials, Processing, Measurement, & Phenomena : JVST B. Sep, 2016  |   Pubmed ID: 27648391
• Isomer Separation of Polybrominated Diphenyl Ether Metabolites Using NanoESI-TIMS-MS
  International Journal for Ion Mobility Spectrometry : Official Publication of the International Society for Ion Mobility Spectrometry. Sep, 2016  |   Pubmed ID: 27642261
• Analysis of Chemotherapeutic Drug Delivery at the Single Cell Level Using 3D-MSI-TOF-SIMS
  Journal of the American Society for Mass Spectrometry. Dec, 2016  |   Pubmed ID: 27582118
• Fast, Ultra-trace Detection of Juvenile Hormone III from Mosquitoes Using Mass Spectrometry
  Talanta. Oct, 2016  |   Pubmed ID: 27474320
• Oversampling Selective Accumulation Trapped Ion Mobility Spectrometry Coupled to FT-ICR MS: Fundamentals and Applications
  Analytical Chemistry. Jul, 2016  |   Pubmed ID: 27340830
• Increasing Polyaromatic Hydrocarbon (PAH) Molecular Coverage During Fossil Oil Analysis by Combining Gas Chromatography and Atmospheric-Pressure Laser Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (FT-ICR MS)
  Energy & Fuels : an American Chemical Society Journal. Jan, 2016  |   Pubmed ID: 27212790
• Characterization of the Photophysical, Thermodynamic, and Structural Properties of the Terbium(III)-DREAM Complex
  Biochemistry. Mar, 2016  |   Pubmed ID: 26901070
• Theoretical Predictor for Candidate Structure Assignment from IMS Data of Biomolecule-related Conformational Space
  International Journal for Ion Mobility Spectrometry : Official Publication of the International Society for Ion Mobility Spectrometry. Jun, 2015  |   Pubmed ID: 27330407
• Towards Unsupervised Polyaromatic Hydrocarbons Structural Assignment from SA-TIMS-FTMS Data
  International Journal for Ion Mobility Spectrometry : Official Publication of the International Society for Ion Mobility Spectrometry. Oct, 2015  |   Pubmed ID: 26525904
• Lifetimes and Stabilities of Familiar Explosive Molecular Adduct Complexes During Ion Mobility Measurements
  The Analyst. Aug, 2015  |   Pubmed ID: 26153567
• The Dimerization State of the Mammalian High Mobility Group Protein AT-Hook 2 (HMGA2)
  PloS One. 2015  |   Pubmed ID: 26114780
• Targeted High-resolution Ion Mobility Separation Coupled to Ultrahigh-resolution Mass Spectrometry of Endocrine Disruptors in Complex Mixtures
  Analytical Chemistry. Apr, 2015  |   Pubmed ID: 25818070
• Kinetic Intermediates of Holo- and Apo-myoglobin Studied Using HDX-TIMS-MS and Molecular Dynamic Simulations
  Journal of the American Society for Mass Spectrometry. Apr, 2015  |   Pubmed ID: 25690175
• Changes in Lipid Distribution in E. Coli Strains in Response to Norfloxacin
  Journal of Mass Spectrometry : JMS. Jan, 2015  |   Pubmed ID: 25601679
• Flavin Adenine Dinucleotide Structural Motifs: from Solution to Gas Phase
  Analytical Chemistry. Oct, 2014  |   Pubmed ID: 25222439
• Secondary Ion Mass Spectrometry Imaging of Dictyostelium Discoideum Aggregation Streams
  PloS One. 2014  |   Pubmed ID: 24911189
• Ion Dynamics in a Trapped Ion Mobility Spectrometer
  The Analyst. Apr, 2014  |   Pubmed ID: 24571000
• Direct Observation of Differences of Carotenoid Polyene Chain Cis/trans Isomers Resulting from Structural Topology
  Analytical Chemistry. Feb, 2014  |   Pubmed ID: 24428664
• Isomerization Kinetics of AT Hook Decapeptide Solution Structures
  Analytical Chemistry. Jan, 2014  |   Pubmed ID: 24364733
• Alkali Halide Nanotubes: Structure and Stability
  The Journal of Physical Chemistry. C, Nanomaterials and Interfaces. Mar, 2012  |   Pubmed ID: 24376901
• Bi-Directional Ion Emission from Massive Gold Cluster Impacts on Nanometric Carbon Foils
  The Journal of Physical Chemistry. C, Nanomaterials and Interfaces. Apr, 2012  |   Pubmed ID: 22888385
• Alkali Halide Clusters Produced by Fast Ion Impact
  Nuclear Instruments & Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms. Feb, 2012  |   Pubmed ID: 22389542
• Analysis of Fluorescent Proteins with a Nanoparticle Probe
  The Journal of Physical Chemistry Letters. Feb, 2012  |   Pubmed ID: 22308203
• Gas-phase Separation Using a Trapped Ion Mobility Spectrometer
  International Journal for Ion Mobility Spectrometry : Official Publication of the International Society for Ion Mobility Spectrometry. Sep, 2011  |   Pubmed ID: 24163587
• Analysis of Native Biological Surfaces Using a 100 KV Massive Gold Cluster Source
  Analytical Chemistry. Nov, 2011  |   Pubmed ID: 21967684
• A Study of Ion-Neutral Collision Cross Section Values for Low Charge States of Peptides, Proteins, and Peptide/Protein Complexes
  International Journal of Mass Spectrometry. Dec, 2010  |   Pubmed ID: 21503273
• Amino Acid Influence on Copper Binding to Peptides: Cysteine Versus Arginine
  Journal of the American Society for Mass Spectrometry. Apr, 2010  |   Pubmed ID: 20138783
• Petroleum Crude Oil Characterization by IMS-MS and FTICR MS
  Analytical Chemistry. Dec, 2009  |   Pubmed ID: 19904990
• Theoretical and Experimental Study of Negative LiF Clusters Produced by Fast Ion Impact on a Polycrystalline 7LiF Target
  The Journal of Physical Chemistry. A. Dec, 2009  |   Pubmed ID: 19685887
• A New Copper Containing MALDI Matrix That Yields High Abundances of [peptide + Cu]+ Ions
  Journal of the American Society for Mass Spectrometry. Jul, 2009  |   Pubmed ID: 19318231
• A Novel Approach to Collision-induced Dissociation (CID) for Ion Mobility-mass Spectrometry Experiments
  Journal of the American Society for Mass Spectrometry. Jun, 2009  |   Pubmed ID: 19135385
• Ion Mobility-mass Spectrometer Interface for Collisional Activation of Mobility Separated Ions
  Analytical Chemistry. Jan, 2009  |   Pubmed ID: 19072664
• Characterization of (NH3)(n=1-6)NH+ Clusters Produced by 252Cf Fragments Impact Onto a NH3 Condensed Target
  The Journal of Physical Chemistry. A. Aug, 2007  |   Pubmed ID: 17685500