Frank B. Furnari Ludwig Institute for Cancer Research Biography Publications Institution JoVE Articles Frank B. Furnari has not added a biography. If you are Frank B. Furnari and would like to personalize this page please email our Author Liaison for assistance. Publications Glioblastoma Cellular Cross-talk Converges on NF-κB to Attenuate EGFR Inhibitor Sensitivity Genes & Development. Jul, 2017 | Pubmed ID: 28724615 PTEN Regulates Glioblastoma Oncogenesis Through Chromatin-associated Complexes of DAXX and Histone H3.3 Nature Communications. May, 2017 | Pubmed ID: 28497778 Extrachromosomal Oncogene Amplification Drives Tumour Evolution and Genetic Heterogeneity Nature. 03, 2017 | Pubmed ID: 28178237 Inhibition of Radiation-induced Glioblastoma Invasion by Genetic and Pharmacological Targeting of MDA-9/Syntenin Proceedings of the National Academy of Sciences of the United States of America. 01, 2017 | Pubmed ID: 28011764 Simultaneous Blockade of Interacting CK2 and EGFR Pathways by Tumor-targeting Nanobioconjugates Increases Therapeutic Efficacy Against Glioblastoma Multiforme Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2016 | Pubmed ID: 27825958 An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers Cancer Cell. Nov, 2016 | Pubmed ID: 27746144 The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System Xc(-) Cancer Research. 05, 2016 | Pubmed ID: 26980765 EGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling Molecular Cell. Oct, 2015 | Pubmed ID: 26455392 Orthogonal Targeting of EGFRvIII Expressing Glioblastomas Through Simultaneous EGFR and PLK1 Inhibition Oncotarget. May, 2015 | Pubmed ID: 26059434 Heterogeneity of Epidermal Growth Factor Receptor Signalling Networks in Glioblastoma Nature Reviews. Cancer. May, 2015 | Pubmed ID: 25855404 Cancer-associated Protein Kinase C Mutations Reveal Kinase's Role As Tumor Suppressor Cell. Jan, 2015 | Pubmed ID: 25619690 A Urokinase Receptor-Bim Signaling Axis Emerges During EGFR Inhibitor Resistance in Mutant EGFR Glioblastoma Cancer Research. Jan, 2015 | Pubmed ID: 25432173 A Unified Nomenclature and Amino Acid Numbering for Human PTEN Science Signaling. Jul, 2014 | Pubmed ID: 24985344 Suppression of MicroRNA-9 by Mutant EGFR Signaling Upregulates FOXP1 to Enhance Glioblastoma Tumorigenicity Cancer Research. Mar, 2014 | Pubmed ID: 24436148 Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA Science (New York, N.Y.). Jan, 2014 | Pubmed ID: 24310612 Therapeutic Resistance in Cancer: MicroRNA Regulation of EGFR Signaling Networks Cancer Biology & Medicine. Dec, 2013 | Pubmed ID: 24349829 The MTOR Kinase Inhibitors, CC214-1 and CC214-2, Preferentially Block the Growth of EGFRvIII-activated Glioblastomas Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2013 | Pubmed ID: 24030701 A Tale of Two Approaches: Complementary Mechanisms of Cytotoxic and Targeted Therapy Resistance May Inform Next-generation Cancer Treatments Carcinogenesis. Apr, 2013 | Pubmed ID: 23455378 抗表皮生长因子受体抑制剂的抑癌基因 PTEN 抑癌在 240 酪氨酸磷酸化介导的胶质母细胞瘤。 Proceedings of the National Academy of Sciences of the United States of America. Aug, 2012 | Pubmed ID: 22891331 Src 激活诱导的 De2-7EGFR (EGFRvIII) 在脑胶质瘤细胞中的线粒体本地化: 对糖代谢的影响。 Journal of Cell Science. Sep, 2011 | Pubmed ID: 21878501 Report from the Fifth National Cancer Institute Mouse Models of Human Cancers Consortium Nervous System Tumors Workshop Neuro-oncology. Jul, 2011 | Pubmed ID: 21727208 Malignant Astrocytic Glioma: Genetics, Biology, and Paths to Treatment Genes & Development. Nov, 2007 | Pubmed ID: 17974913 胶质瘤表皮生长因子受体特异性抗体的效果受到激素受体、 激活状态和 Heterodimerization。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2007 | Pubmed ID: 17363548 PCAF Modulates PTEN Activity The Journal of Biological Chemistry. Sep, 2006 | Pubmed ID: 16829519 治疗人类肿瘤异种移植与单克隆抗体 806 与原型表皮生长因子受体特异性抗体结合生成增强抗肿瘤活性。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2005 | Pubmed ID: 16144944 PTEN: a Novel Anti-oncogenic Function Independent of Phosphatase Activity Cell Cycle (Georgetown, Tex.). Apr, 2005 | Pubmed ID: 15753657 Cellular Transformation by the MSP58 Oncogene is Inhibited by Its Physical Interaction with the PTEN Tumor Suppressor Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005 | Pubmed ID: 15659546 Alix/AIP1 Cbl-刚毛/CIN85 复合拮抗表皮生长因子受体下调。 Molecular and Cellular Biology. Oct, 2004 | Pubmed ID: 15456872 Mutant Epidermal Growth Factor Receptor Signaling Down-regulates P27 Through Activation of the Phosphatidylinositol 3-kinase/Akt Pathway in Glioblastomas Cancer Research. Nov, 2002 | Pubmed ID: 12438278 一种新型七跨膜受体诱导期间确定的差异表达的星形胶质细胞分化的早期步骤。 Journal of Neurochemistry. May, 2002 | Pubmed ID: 12065666 The Phosphoinositol Phosphatase Activity of PTEN Mediates a Serum-sensitive G1 Growth Arrest in Glioma Cells Cancer Research. Nov, 1998 | Pubmed ID: 9823298 In Vitro Loss of Heterozygosity Targets the PTEN/MMAC1 Gene in Melanoma Proceedings of the National Academy of Sciences of the United States of America. Aug, 1998 | Pubmed ID: 9689095 Growth Suppression of Glioma Cells by PTEN Requires a Functional Phosphatase Catalytic Domain Proceedings of the National Academy of Sciences of the United States of America. Nov, 1997 | Pubmed ID: 9356475 胶质瘤移植中体内成像的荧光分子层析成像研究 Jorge A. Benitez*1, Ciro Zanca*1, Jianhui Ma1, Webster K. Cavenee1,2,3, Frank B. Furnari1,2,4 1Ludwig Institute for Cancer Research, 2Moores Cancer Center, School of Medicine, University of California, San Diego, 3Department of Pathology, School of Medicine, University of California, San Diego, 4Department of Medicine, School of Medicine, University of California, San Diego JoVE 57448 Cancer Research
胶质瘤移植中体内成像的荧光分子层析成像研究 Jorge A. Benitez*1, Ciro Zanca*1, Jianhui Ma1, Webster K. Cavenee1,2,3, Frank B. Furnari1,2,4 1Ludwig Institute for Cancer Research, 2Moores Cancer Center, School of Medicine, University of California, San Diego, 3Department of Pathology, School of Medicine, University of California, San Diego, 4Department of Medicine, School of Medicine, University of California, San Diego JoVE 57448 Cancer Research