Frank Tacke Department of Medicine III RWTH University-Hospital Aachen Biography Publications Institution JoVE Articles Frank Tacke has not added a biography. If you are Frank Tacke and would like to personalize this page please email our Author Liaison for assistance. Publications CXCL9 is a Prognostic Marker in Patients with Liver Cirrhosis Receiving Transjugular Intrahepatic Portosystemic Shunt Journal of Hepatology. Feb, 2015 | Pubmed ID: 25457205 Fluorescent Cell-traceable Dexamethasone-loaded Liposomes for the Treatment of Inflammatory Liver Diseases Biomaterials. Jan, 2015 | Pubmed ID: 25453965 Therapeutic Targeting of Liver Inflammation and Fibrosis by Nanomedicine Hepatobiliary Surgery and Nutrition. Dec, 2014 | Pubmed ID: 25568860 Cellular and Molecular Functions of Hepatic Stellate Cells in Inflammatory Responses and Liver Immunology Hepatobiliary Surgery and Nutrition. Dec, 2014 | Pubmed ID: 25568859 Immune Mechanisms in Acetaminophen-induced Acute Liver Failure Hepatobiliary Surgery and Nutrition. Dec, 2014 | Pubmed ID: 25568858 Liver Immunology: New Perspectives Hepatobiliary Surgery and Nutrition. Dec, 2014 | Pubmed ID: 25568857 Reply: To PMID 24481979 Gastroenterology. Dec, 2014 | Pubmed ID: 25457849 Variceal Bleeding in Liver Cirrhosis at the ICU: Sufficient Data to Treat Adrenal Insufficiency?* Critical Care Medicine. Dec, 2014 | Pubmed ID: 25402288 Pharmacological Inhibition of the Chemokine CXCL16 Diminishes Liver Macrophage Infiltration and Steatohepatitis in Chronic Hepatic Injury PloS One. 2014 | Pubmed ID: 25372401 Cyclic Adenosine Monophosphate-responsive Element Modulator Alpha Overexpression Impairs Function of Hepatic Myeloid-derived Suppressor Cells and Aggravates Immune-mediated Hepatitis in Mice Hepatology (Baltimore, Md.). Oct, 2014 | Pubmed ID: 25330465 Distinct Patterns of IgG and IgA Against Food and Microbial Antigens in Serum and Feces of Patients with Inflammatory Bowel Diseases PloS One. 2014 | Pubmed ID: 25215528 Interleukins in Chronic Liver Disease: Lessons Learned from Experimental Mouse Models Clinical and Experimental Gastroenterology. 2014 | Pubmed ID: 25214799 Roles for Chemokines in Liver Disease Gastroenterology. Sep, 2014 | Pubmed ID: 25066692 Elevated MiR-122 Serum Levels Are an Independent Marker of Liver Injury in Inflammatory Diseases Liver International : Official Journal of the International Association for the Study of the Liver. Jul, 2014 | Pubmed ID: 25039534 Molecular Identification of Hepatitis B Virus Genotypes/subgenotypes: Revised Classification Hurdles and Updated Resolutions World Journal of Gastroenterology : WJG. Jun, 2014 | Pubmed ID: 24966586 A Positive Feedback Loop Between RIP3 and JNK Controls Non-alcoholic Steatohepatitis EMBO Molecular Medicine. 2014 | Pubmed ID: 24963148 GLP-1 Secretion is Increased by Inflammatory Stimuli in an IL-6-dependent Manner, Leading to Hyperinsulinemia and Blood Glucose Lowering Diabetes. Oct, 2014 | Pubmed ID: 24947356 Role of Gamma-delta T Cells in Liver Inflammation and Fibrosis World Journal of Gastrointestinal Pathophysiology. May, 2014 | Pubmed ID: 24891982 Translation Control of TAK1 MRNA by HnRNP K Modulates LPS-induced Macrophage Activation RNA (New York, N.Y.). Jun, 2014 | Pubmed ID: 24751651 Administration of Proton Pump Inhibitors in Critically Ill Medical Patients is Associated with Increased Risk of Developing Clostridium Difficile-associated Diarrhea Journal of Critical Care. Aug, 2014 | Pubmed ID: 24674763 Liposomal Encapsulation of Dexamethasone Modulates Cytotoxicity, Inflammatory Cytokine Response, and Migratory Properties of Primary Human Macrophages Nanomedicine : Nanotechnology, Biology, and Medicine. Aug, 2014 | Pubmed ID: 24607939 Clinical Relevance and Cellular Source of Elevated Soluble Urokinase Plasminogen Activator Receptor (suPAR) in Acute Liver Failure Liver International : Official Journal of the International Association for the Study of the Liver. Feb, 2014 | Pubmed ID: 24575897 CCL2-dependent Infiltrating Macrophages Promote Angiogenesis in Progressive Liver Fibrosis Gut. Dec, 2014 | Pubmed ID: 24561613 Pharmacological Inhibition of the Chemokine C-C Motif Chemokine Ligand 2 (monocyte Chemoattractant Protein 1) Accelerates Liver Fibrosis Regression by Suppressing Ly-6C(+) Macrophage Infiltration in Mice Hepatology (Baltimore, Md.). Mar, 2014 | Pubmed ID: 24481979 High Prevalence of Y-box Protein-1/p18 Fragment in Plasma of Patients with Malignancies of Different Origin BMC Cancer. 2014 | Pubmed ID: 24443788 Levels of Circulating MiR-133a Are Elevated in Sepsis and Predict Mortality in Critically Ill Patients Critical Care Medicine. May, 2014 | Pubmed ID: 24413579 Macrophage Heterogeneity in Liver Injury and Fibrosis Journal of Hepatology. May, 2014 | Pubmed ID: 24412603 Chemokine Receptor CCR6-dependent Accumulation of γδ T Cells in Injured Liver Restricts Hepatic Inflammation and Fibrosis Hepatology (Baltimore, Md.). Feb, 2014 | Pubmed ID: 23959575 Eat More Carrots? Dampening Cell Death in Ethanol-induced Liver Fibrosis by β-carotene Hepatobiliary Surgery and Nutrition. Oct, 2013 | Pubmed ID: 24570954 Role of Lymphocytes in Liver Cancer Oncoimmunology. Nov, 2013 | Pubmed ID: 24498546 Experimental Liver Fibrosis Research: Update on Animal Models, Legal Issues and Translational Aspects Fibrogenesis & Tissue Repair. 2013 | Pubmed ID: 24274743 HBV Subgenotypes D1, D2, D-del! Are 'Old' Genotyping Methods Interpreted Correctly? Hepatitis Monthly. 2013 | Pubmed ID: 24066000 U6 is Unsuitable for Normalization of Serum MiRNA Levels in Patients with Sepsis or Liver Fibrosis Experimental & Molecular Medicine. 2013 | Pubmed ID: 24052167 RIP3 Inhibits Inflammatory Hepatocarcinogenesis but Promotes Cholestasis by Controlling Caspase-8- and JNK-dependent Compensatory Cell Proliferation Cell Reports. Aug, 2013 | Pubmed ID: 23972991 Elevated Asymmetric Dimethylarginine Levels Predict Short- and Long-term Mortality Risk in Critically Ill Patients Journal of Critical Care. Dec, 2013 | Pubmed ID: 23953490 Regulation and Prognostic Relevance of Symmetric Dimethylarginine Serum Concentrations in Critical Illness and Sepsis Mediators of Inflammation. 2013 | Pubmed ID: 23935249 YB-1 is an Early and Central Mediator of Bacterial and Sterile Inflammation in Vivo Journal of Immunology (Baltimore, Md. : 1950). Sep, 2013 | Pubmed ID: 23872051 Frequency and Phenotype of Human Circulating and Intrahepatic Natural Killer Cell Subsets is Differentially Regulated According to Stage of Chronic Liver Disease Digestion. 2013 | Pubmed ID: 23774822 Overexpression of C-myc in Hepatocytes Promotes Activation of Hepatic Stellate Cells and Facilitates the Onset of Liver Fibrosis Biochimica Et Biophysica Acta. Oct, 2013 | Pubmed ID: 23770341 Chemokine Receptor CXCR6-dependent Hepatic NK T Cell Accumulation Promotes Inflammation and Liver Fibrosis Journal of Immunology (Baltimore, Md. : 1950). May, 2013 | Pubmed ID: 23596313 Met-CCL5 Modifies Monocyte Subpopulations During Liver Fibrosis Regression International Journal of Clinical and Experimental Pathology. 2013 | Pubmed ID: 23573314 Serum Sodium Based Modification of the MELD Does Not Improve Prediction of Outcome in Acute Liver Failure BMC Gastroenterology. 2013 | Pubmed ID: 23551795 From NAFLD to NASH to Fibrosis to HCC: Role of Dendritic Cell Populations in the Liver Hepatology (Baltimore, Md.). Aug, 2013 | Pubmed ID: 23519833 Elastin-based Molecular MRI of Liver Fibrosis Hepatology (Baltimore, Md.). Oct, 2013 | Pubmed ID: 23424008 Protective Effects of Lipocalin-2 (LCN2) in Acute Liver Injury Suggest a Novel Function in Liver Homeostasis Biochimica Et Biophysica Acta. May, 2013 | Pubmed ID: 23376114 Circulating MicroRNA-150 Serum Levels Predict Survival in Patients with Critical Illness and Sepsis PloS One. 2013 | Pubmed ID: 23372743 Serum Concentrations of A Proliferation-Inducing Ligand (APRIL) Are Elevated in Sepsis and Predict Mortality in Critically Ill Patients Journal of Critical Care. Oct, 2013 | Pubmed ID: 23337484 TNFα-mediated Liver Destruction by Kupffer Cells and Ly6Chi Monocytes During Entamoeba Histolytica Infection PLoS Pathogens. Jan, 2013 | Pubmed ID: 23300453 CXCR6.Gfpレポーターマウスを使用して、健康で罹患肝臓における免疫細胞の長期生体内多光子顕微鏡イメージング Felix Heymann*1, Patricia M. Niemietz*1, Julia Peusquens1, Can Ergen1, Marlene Kohlhepp1, Jana C. Mossanen1, Carlo Schneider1, Michael Vogt2, Rene H. Tolba3, Christian Trautwein1, Christian Martin4, Frank Tacke1 1Department of Medicine III, RWTH University-Hospital Aachen, 2IZKF Aachen Core Facility "Two-Photon Imaging", RWTH University-Hospital Aachen, 3Institute for Laboratory Animal Science & Experimental Surgery, RWTH Aachen University, 4Institute for Pharmacology, RWTH University-Hospital Aachen Immunology and Infection マウスにおける胆管結紮：閉塞性胆汁うっ滞による炎症性肝障害と線維症の誘発 Carmen G. Tag1, Sibille Sauer-Lehnen1, Sabine Weiskirchen1, Erawan Borkham-Kamphorst1, René H. Tolba2, Frank Tacke3, Ralf Weiskirchen1 1Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry, RWTH Aachen University, 2Institute for Laboratory Animal Science and Experimental Surgery, RWTH Aachen University, 3Department of Medicine III, RWTH Aachen University Medicine
CXCR6.Gfpレポーターマウスを使用して、健康で罹患肝臓における免疫細胞の長期生体内多光子顕微鏡イメージング Felix Heymann*1, Patricia M. Niemietz*1, Julia Peusquens1, Can Ergen1, Marlene Kohlhepp1, Jana C. Mossanen1, Carlo Schneider1, Michael Vogt2, Rene H. Tolba3, Christian Trautwein1, Christian Martin4, Frank Tacke1 1Department of Medicine III, RWTH University-Hospital Aachen, 2IZKF Aachen Core Facility "Two-Photon Imaging", RWTH University-Hospital Aachen, 3Institute for Laboratory Animal Science & Experimental Surgery, RWTH Aachen University, 4Institute for Pharmacology, RWTH University-Hospital Aachen Immunology and Infection
マウスにおける胆管結紮：閉塞性胆汁うっ滞による炎症性肝障害と線維症の誘発 Carmen G. Tag1, Sibille Sauer-Lehnen1, Sabine Weiskirchen1, Erawan Borkham-Kamphorst1, René H. Tolba2, Frank Tacke3, Ralf Weiskirchen1 1Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry, RWTH Aachen University, 2Institute for Laboratory Animal Science and Experimental Surgery, RWTH Aachen University, 3Department of Medicine III, RWTH Aachen University Medicine
