Frank von Delft Diamond Light Source Ltd, Harwell Science and Innovation Campus Biography Publications Institution JoVE Articles Frank von Delft has not added a biography. If you are Frank von Delft and would like to personalize this page please email our Author Liaison for assistance. Publications Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking Science Advances. 04, 2021 | Pubmed ID: 33853786 Discovery of Allosteric Binding Sites by Crystallographic Fragment Screening Current Opinion in Structural Biology. 12, 2020 | Pubmed ID: 33171388 Crystallographic and Electrophilic Fragment Screening of the SARS-CoV-2 Main Protease Nature Communications. 10, 2020 | Pubmed ID: 33028810 Crowdsourcing Drug Discovery for Pandemics Nature Chemistry. 07, 2020 | Pubmed ID: 32555379 Achieving a Good Crystal System for Crystallographic X-Ray Fragment Screening Methods in Enzymology. 2018 | Pubmed ID: 30390801 A Poised Fragment Library Enables Rapid Synthetic Expansion Yielding the First Reported Inhibitors of PHIP(2), an Atypical Bromodomain Chemical Science. Mar, 2016 | Pubmed ID: 29910922 Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source Alice Douangamath*1,2, Ailsa Powell*1,2, Daren Fearon*1,2, Patrick M. Collins1,2, Romain Talon1,2,3, Tobias Krojer3,4, Rachael Skyner1,2, Jose Brandao-Neto1,2, Louise Dunnett1,2, Alexandre Dias1,2, Anthony Aimon1,2,3, Nicholas M. Pearce1,3, Conor Wild3,5, Tyler Gorrie-Stone1, Frank von Delft1,2,3,4,6 1Diamond Light Source Ltd, Harwell Science and Innovation Campus, 2Research Complex at Harwell, Harwell Science and Innovation Campus, 3Structural Genomics Consortium, University of Oxford, 4Centre for Medicines Discovery, University of Oxford, 5Oxford Protein Informatics Group, Department of Statistics, Oxford University, 6Department of Biochemistry, University of Johannesburg JoVE 62414 Chemistry
Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source Alice Douangamath*1,2, Ailsa Powell*1,2, Daren Fearon*1,2, Patrick M. Collins1,2, Romain Talon1,2,3, Tobias Krojer3,4, Rachael Skyner1,2, Jose Brandao-Neto1,2, Louise Dunnett1,2, Alexandre Dias1,2, Anthony Aimon1,2,3, Nicholas M. Pearce1,3, Conor Wild3,5, Tyler Gorrie-Stone1, Frank von Delft1,2,3,4,6 1Diamond Light Source Ltd, Harwell Science and Innovation Campus, 2Research Complex at Harwell, Harwell Science and Innovation Campus, 3Structural Genomics Consortium, University of Oxford, 4Centre for Medicines Discovery, University of Oxford, 5Oxford Protein Informatics Group, Department of Statistics, Oxford University, 6Department of Biochemistry, University of Johannesburg JoVE 62414 Chemistry
