Friedemann Weber

Publications

• Segmented Negative-strand RNA Viruses and RIG-I: Divide (your Genome) and Rule
  Current Opinion in Microbiology. Jun, 2014  |   Pubmed ID: 24930021
• RIG-I-like Receptors and Negative-strand RNA Viruses: RLRly Bird Catches Some Worms
  Cytokine & Growth Factor Reviews. May, 2014  |   Pubmed ID: 24894317
• Structural Insights into RNA Encapsidation and Helical Assembly of the Toscana Virus Nucleoprotein
  Nucleic Acids Research. 2014  |   Pubmed ID: 24688060
• Virulence Factor NSs of Rift Valley Fever Virus Recruits the F-box Protein FBXO3 to Degrade Subunit P62 of General Transcription Factor TFIIH
  Journal of Virology. Mar, 2014  |   Pubmed ID: 24403578
• Viperin is an Iron-sulfur Protein That Inhibits Genome Synthesis of Tick-borne Encephalitis Virus Via Radical SAM Domain Activity
  Cellular Microbiology. Jun, 2014  |   Pubmed ID: 24245804
• Middle East Respiratory Syndrome Coronavirus Accessory Protein 4a is a Type I Interferon Antagonist
  Journal of Virology. Nov, 2013  |   Pubmed ID: 24027320
• IFIT2 is an Effector Protein of Type I IFN-mediated Amplification of Lipopolysaccharide (LPS)-induced TNF-α Secretion and LPS-induced Endotoxin Shock
  Journal of Immunology (Baltimore, Md. : 1950). Oct, 2013  |   Pubmed ID: 24014876
• Systems to Establish Bunyavirus Genome Replication in the Absence of Transcription
  Journal of Virology. Jul, 2013  |   Pubmed ID: 23698297
• Structural Basis for Encapsidation of Genomic RNA by La Crosse Orthobunyavirus Nucleoprotein
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2013  |   Pubmed ID: 23589854
• Incoming RNA Virus Nucleocapsids Containing a 5'-triphosphorylated Genome Activate RIG-I and Antiviral Signaling
  Cell Host & Microbe. Mar, 2013  |   Pubmed ID: 23498958
• Human Cell Tropism and Innate Immune System Interactions of Human Respiratory Coronavirus EMC Compared to Those of Severe Acute Respiratory Syndrome Coronavirus
  Journal of Virology. May, 2013  |   Pubmed ID: 23449793
• Severe Fever with Thrombocytopenia Virus Glycoproteins Are Targeted by Neutralizing Antibodies and Can Use DC-SIGN As a Receptor for PH-dependent Entry into Human and Animal Cell Lines
  Journal of Virology. Apr, 2013  |   Pubmed ID: 23388721
• Structure of Crimean-Congo Hemorrhagic Fever Virus Nucleoprotein: Superhelical Homo-oligomers and the Role of Caspase-3 Cleavage
  Journal of Virology. Nov, 2012  |   Pubmed ID: 22951837
• Viral Immune Modulators Perturb the Human Molecular Network by Common and Unique Strategies
  Nature. Jul, 2012  |   Pubmed ID: 22810585
• Reverse Genetics of SARS-related Coronavirus Using Vaccinia Virus-based Recombination
  PloS One. 2012  |   Pubmed ID: 22412934
• Regulatory, Biosafety and Safety Challenges for Novel Cells As Substrates for Human Vaccines
  Vaccine. Apr, 2012  |   Pubmed ID: 22342707
• Induction of DNA Damage Signaling Upon Rift Valley Fever Virus Infection Results in Cell Cycle Arrest and Increased Viral Replication
  The Journal of Biological Chemistry. Mar, 2012  |   Pubmed ID: 22223653
• The SARS-coronavirus-host Interactome: Identification of Cyclophilins As Target for Pan-coronavirus Inhibitors
  PLoS Pathogens. Oct, 2011  |   Pubmed ID: 22046132
• IFIT1 is an Antiviral Protein That Recognizes 5'-triphosphate RNA
  Nature Immunology. Jul, 2011  |   Pubmed ID: 21642987
• Hiding from Intracellular Pattern Recognition Receptors, a Passive Strategy of Flavivirus Immune Evasion
  Virulence. May-Jun, 2011  |   Pubmed ID: 21555916
• Completion of Hepatitis C Virus Replication Cycle in Heterokaryons Excludes Dominant Restrictions in Human Non-liver and Mouse Liver Cell Lines
  PLoS Pathogens. Apr, 2011  |   Pubmed ID: 21552323
• The ADP-ribose-1''-monophosphatase Domains of Severe Acute Respiratory Syndrome Coronavirus and Human Coronavirus 229E Mediate Resistance to Antiviral Interferon Responses
  The Journal of General Virology. Aug, 2011  |   Pubmed ID: 21525212
• Old World Hantaviruses Do Not Produce Detectable Amounts of DsRNA in Infected Cells and the 5' Termini of Their Genomic RNAs Are Monophosphorylated
  The Journal of General Virology. May, 2011  |   Pubmed ID: 21289157
• Interferon Antagonist NSs of La Crosse Virus Triggers a DNA Damage Response-like Degradation of Transcribing RNA Polymerase II
  The Journal of Biological Chemistry. Feb, 2011  |   Pubmed ID: 21118815
• Toscana Virus Induces Interferon Although Its NSs Protein Reveals Antagonistic Activity
  The Journal of General Virology. Jan, 2011  |   Pubmed ID: 20861320
• Interferon Interplay Helps Tissue Cells to Cope with SARS-coronavirus Infection
  Virulence. Jul-Aug, 2010  |   Pubmed ID: 21178452
• Bunyaviridae RNA Polymerases (L-protein) Have an N-terminal, Influenza-like Endonuclease Domain, Essential for Viral Cap-dependent Transcription
  PLoS Pathogens. 2010  |   Pubmed ID: 20862319
• Virus-like Particles Expressing the Nucleocapsid Gene As an Efficient Vaccine Against Rift Valley Fever Virus
  Vector Borne and Zoonotic Diseases (Larchmont, N.Y.). Oct, 2010  |   Pubmed ID: 20854024
• Extracellular 2'-5' Oligoadenylate Synthetase Stimulates RNase L-independent Antiviral Activity: a Novel Mechanism of Virus-induced Innate Immunity
  Journal of Virology. Nov, 2010  |   Pubmed ID: 20844035
• Tick-borne Encephalitis Virus Delays Interferon Induction and Hides Its Double-stranded RNA in Intracellular Membrane Vesicles
  Journal of Virology. Sep, 2010  |   Pubmed ID: 20554782
• La Crosse Virus (LACV) Gc Fusion Peptide Mutants Have Impaired Growth and Fusion Phenotypes, but Remain Neurotoxic
  Virology. Sep, 2010  |   Pubmed ID: 20553924
• Molecular Biology of Rift Valley Fever Virus
  The Open Virology Journal. 2010  |   Pubmed ID: 20517489
• Species-independent Bioassay for Sensitive Quantification of Antiviral Type I Interferons
  Virology Journal. 2010  |   Pubmed ID: 20187932
• Differential Downregulation of ACE2 by the Spike Proteins of Severe Acute Respiratory Syndrome Coronavirus and Human Coronavirus NL63
  Journal of Virology. Jan, 2010  |   Pubmed ID: 19864379
• Thogoto Virus ML Protein is a Potent Inhibitor of the Interferon Regulatory Factor-7 Transcription Factor
  The Journal of General Virology. Jan, 2010  |   Pubmed ID: 19812269
• Bunyaviruses and the Type I Interferon System
  Viruses. Dec, 2009  |   Pubmed ID: 21994579
• Interferon Priming Enables Cells to Partially Overturn the SARS Coronavirus-induced Block in Innate Immune Activation
  The Journal of General Virology. Nov, 2009  |   Pubmed ID: 19625461
• NSs Protein of Rift Valley Fever Virus Induces the Specific Degradation of the Double-stranded RNA-dependent Protein Kinase
  Journal of Virology. May, 2009  |   Pubmed ID: 19211744
• Electron Cryo-microscopy and Single-particle Averaging of Rift Valley Fever Virus: Evidence for GN-GC Glycoprotein Heterodimers
  Journal of Virology. Apr, 2009  |   Pubmed ID: 19193794
• Vaccination with Virus-like Particles Protects Mice from Lethal Infection of Rift Valley Fever Virus
  Virology. Mar, 2009  |   Pubmed ID: 19157482
• Efficient Production of Rift Valley Fever Virus-like Particles: The Antiviral Protein MxA Can Inhibit Primary Transcription of Bunyaviruses
  Virology. Mar, 2009  |   Pubmed ID: 19155037
• Severe Acute Respiratory Syndrome Coronavirus Triggers Apoptosis Via Protein Kinase R but is Resistant to Its Antiviral Activity
  Journal of Virology. Mar, 2009  |   Pubmed ID: 19109397
• Interferon and Cytokine Responses to Crimean Congo Hemorrhagic Fever Virus; an Emerging and Neglected Viral Zonoosis
  Cytokine & Growth Factor Reviews. Oct-Dec, 2008  |   Pubmed ID: 19027345
• The Interferon Antagonist ML Protein of Thogoto Virus Targets General Transcription Factor IIB
  Journal of Virology. Nov, 2008  |   Pubmed ID: 18768974
• T7 RNA Polymerase-dependent and -independent Systems for CDNA-based Rescue of Rift Valley Fever Virus
  The Journal of General Virology. Sep, 2008  |   Pubmed ID: 18753225
• Crimean-Congo Hemorrhagic Fever Virus Delays Activation of the Innate Immune Response
  Journal of Medical Virology. Aug, 2008  |   Pubmed ID: 18551619
• Processing of Genome 5' Termini As a Strategy of Negative-strand RNA Viruses to Avoid RIG-I-dependent Interferon Induction
  PloS One. 2008  |   Pubmed ID: 18446221
• Interferon and Cytokine Responses to SARS-coronavirus Infection
  Cytokine & Growth Factor Reviews. Apr, 2008  |   Pubmed ID: 18321765
• Interaction of Hepatitis C Virus with the Type I Interferon System
  World Journal of Gastroenterology : WJG. Sep, 2007  |   Pubmed ID: 17828812
• Tula and Puumala Hantavirus NSs ORFs Are Functional and the Products Inhibit Activation of the Interferon-beta Promoter
  Journal of Medical Virology. Oct, 2007  |   Pubmed ID: 17705180
• Coronavirus Non-structural Protein 1 is a Major Pathogenicity Factor: Implications for the Rational Design of Coronavirus Vaccines
  PLoS Pathogens. Aug, 2007  |   Pubmed ID: 17696607
• Interferon, Mx, and Viral Countermeasures
  Cytokine & Growth Factor Reviews. Oct-Dec, 2007  |   Pubmed ID: 17683972
• La Crosse Bunyavirus Nonstructural Protein NSs Serves to Suppress the Type I Interferon System of Mammalian Hosts
  Journal of Virology. May, 2007  |   Pubmed ID: 17344298
• Viral Suppression of the Interferon System
  Biochimie. Jun-Jul, 2007  |   Pubmed ID: 17336442
• The Intracellular Sites of Early Replication and Budding of SARS-coronavirus
  Virology. May, 2007  |   Pubmed ID: 17210170
• Control of Coronavirus Infection Through Plasmacytoid Dendritic-cell-derived Type I Interferon
  Blood. Feb, 2007  |   Pubmed ID: 16985170
• RIG-I-mediated Antiviral Responses to Single-stranded RNA Bearing 5'-phosphates
  Science (New York, N.Y.). Nov, 2006  |   Pubmed ID: 17038589
• Interaction of Severe Acute Respiratory Syndrome-associated Coronavirus with Dendritic Cells
  The Journal of General Virology. Jul, 2006  |   Pubmed ID: 16760397
• Neurons Produce Type I Interferon During Viral Encephalitis
  Proceedings of the National Academy of Sciences of the United States of America. May, 2006  |   Pubmed ID: 16682623
• Double-stranded RNA is Produced by Positive-strand RNA Viruses and DNA Viruses but Not in Detectable Amounts by Negative-strand RNA Viruses
  Journal of Virology. May, 2006  |   Pubmed ID: 16641297
• Inhibition of Cytokine Gene Expression and Induction of Chemokine Genes in Non-lymphatic Cells Infected with SARS Coronavirus
  Virology Journal. 2006  |   Pubmed ID: 16571117
• Global Suppression of the Host Antiviral Response by Ebola- and Marburgviruses: Increased Antagonism of the Type I Interferon Response is Associated with Enhanced Virulence
  Journal of Virology. Mar, 2006  |   Pubmed ID: 16501110
• Induction of Interferon Synthesis by the PKR-inhibitory VA RNAs of Adenoviruses
  Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. Jan, 2006  |   Pubmed ID: 16426142
• A Target on the Move: Innate and Adaptive Immune Escape Strategies of Hepatitis C Virus
  Antiviral Research. Mar, 2006  |   Pubmed ID: 16413618
• The Interferon Response Circuit: Induction and Suppression by Pathogenic Viruses
  Virology. Jan, 2006  |   Pubmed ID: 16364743
• Activation of Innate Defense Against a Paramyxovirus is Mediated by RIG-I and TLR7 and TLR8 in a Cell-type-specific Manner
  Journal of Virology. Oct, 2005  |   Pubmed ID: 16188996
• Efficient CDNA-based Rescue of La Crosse Bunyaviruses Expressing or Lacking the Nonstructural Protein NSs
  Journal of Virology. Aug, 2005  |   Pubmed ID: 16051834
• Inhibition of Beta Interferon Induction by Severe Acute Respiratory Syndrome Coronavirus Suggests a Two-step Model for Activation of Interferon Regulatory Factor 3
  Journal of Virology. Feb, 2005  |   Pubmed ID: 15681410
• Thogoto Virus ML Protein Suppresses IRF3 Function
  Virology. Jan, 2005  |   Pubmed ID: 15582653
• Inverse Interference: How Viruses Fight the Interferon System
  Viral Immunology. 2004  |   Pubmed ID: 15671747
• NSs Protein of Rift Valley Fever Virus Blocks Interferon Production by Inhibiting Host Gene Transcription
  Journal of Virology. Sep, 2004  |   Pubmed ID: 15331713
• High-efficiency Detection of Severe Acute Respiratory Syndrome Virus Genetic Material
  Journal of Clinical Microbiology. Jun, 2004  |   Pubmed ID: 15184466
• Inhibition of RNA Polymerase II Phosphorylation by a Viral Interferon Antagonist
  The Journal of Biological Chemistry. Jul, 2004  |   Pubmed ID: 15150262
• The Antiviral Effect of Interferon-beta Against SARS-coronavirus is Not Mediated by MxA Protein
  Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology. Jul, 2004  |   Pubmed ID: 15135736
• Inhibition of Dugbe Nairovirus Replication by Human MxA Protein
  Virus Research. Jan, 2004  |   Pubmed ID: 14687945
• Viral Evasion of the Interferon System: Old Viruses, New Tricks
  Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. Apr, 2003  |   Pubmed ID: 12856333
• Bunyamwera Virus Nonstructural Protein NSs Counteracts Interferon Regulatory Factor 3-mediated Induction of Early Cell Death
  Journal of Virology. Jul, 2003  |   Pubmed ID: 12829839
• Functional L Polymerase of La Crosse Virus Allows in Vivo Reconstitution of Recombinant Nucleocapsids
  The Journal of General Virology. May, 2003  |   Pubmed ID: 12692286
• Activation of PKR by Bunyamwera Virus is Independent of the Viral Interferon Antagonist NSs
  Journal of Virology. May, 2003  |   Pubmed ID: 12692253
• Novel Gene Product of Thogoto Virus Segment 6 Codes for an Interferon Antagonist
  Journal of Virology. Feb, 2003  |   Pubmed ID: 12552016
• Antigenic Drift, Antigenic Shift and Interferon Antagonists: How Bunyaviruses Counteract the Immune System
  Virus Research. Sep, 2002  |   Pubmed ID: 12297332
• Bunyamwera Bunyavirus Nonstructural Protein NSs Counteracts the Induction of Alpha/beta Interferon
  Journal of Virology. Aug, 2002  |   Pubmed ID: 12133999