Gábor Mező MTA-ELTE Research Group of Peptide Chemistry Eötvös Loránd University Biography Publications Institution JoVE Articles Gábor Mező has not added a biography. If you are Gábor Mező and would like to personalize this page please email our Author Liaison for assistance. Publications Cellular Uptake Mechanism of Cationic Branched Polypeptides with Poly[l-Lys] Backbone ACS Combinatorial Science. Mar, 2017 | Pubmed ID: 28276242 Synthesis, Characterization and Systematic Comparison of FITC-labelled GnRH-I, -II and -III Analogues on Various Tumour Cells Journal of Peptide Science : an Official Publication of the European Peptide Society. Aug, 2016 | Pubmed ID: 27443981 Improved in Vivo Antitumor Effect of a Daunorubicin - GnRH-III Bioconjugate Modified by Apoptosis Inducing Agent Butyric Acid on Colorectal Carcinoma Bearing Mice Investigational New Drugs. Aug, 2016 | Pubmed ID: 27146514 A Double-Clicking Bis-Azide Fluorogenic Dye for Bioorthogonal Self-Labeling Peptide Tags Chemistry (Weinheim an Der Bergstrasse, Germany). Apr, 2016 | Pubmed ID: 27010966 [Studying the Tumor Growth Inhibitory Effect of Modified GnRH-III-anthracycline Bioconjugates in Subcutaneous Vs. Orthotopic Models in Vivo] Magyar Onkologia. Dec, 2015 | Pubmed ID: 26665191 Comparative in Vitro Biological Evaluation of Daunorubicin Containing GnRH-I and GnRH-II Conjugates Developed for Tumor Targeting Journal of Peptide Science : an Official Publication of the European Peptide Society. May, 2015 | Pubmed ID: 25908176 Modification of Daunorubicin-GnRH-III Bioconjugates with Oligoethylene Glycol Derivatives to Improve Solubility and Bioavailability for Targeted Cancer Chemotherapy Biopolymers. May, 2015 | Pubmed ID: 25753049 Antimycobacterial Activity of Peptide Conjugate of Pyridopyrimidine Derivative Against Mycobacterium Tuberculosis in a Series of in Vitro and in Vivo Models Tuberculosis (Edinburgh, Scotland). Jun, 2015 | Pubmed ID: 25728610 Development of Cyclic NGR Peptides with Thioether Linkage: Structure and Dynamics Determining Deamidation and Bioactivity Journal of Medicinal Chemistry. Feb, 2015 | Pubmed ID: 25646854 In Vivo Imaging of Aminopeptidase N (CD13) Receptors in Experimental Renal Tumors Using the Novel Radiotracer (68)Ga-NOTA-c(NGR) European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Mar, 2015 | Pubmed ID: 25592229 Protein Expression Profile of HT-29 Human Colon Cancer Cells After Treatment with a Cytotoxic Daunorubicin-GnRH-III Derivative Bioconjugate PloS One. 2014 | Pubmed ID: 24718594 Leishmania Braziliensis: Cytotoxic, Cytostatic and Chemotactic Effects of Poly-lysine-methotrexate-conjugates Experimental Parasitology. Sep, 2013 | Pubmed ID: 23816643 Binding of New Cationic Porphyrin-tetrapeptide Conjugates to Nucleoprotein Complexes Biophysical Chemistry. Jul-Aug, 2013 | Pubmed ID: 23603112 Synthesis, Enzymatic Stability and in Vitro Cytostatic Effect of Daunorubicin-GnRH-III Derivative Dimers Bioorganic & Medicinal Chemistry Letters. Apr, 2013 | Pubmed ID: 23434423 NIR Mega-Stokes Fluorophores for Bioorthogonal Labeling and Energy Transfer Systems--an Efficient Quencher for Daunomycin Chemistry, an Asian Journal. Feb, 2013 | Pubmed ID: 23225500 Investigation on Chemotactic Drug Targeting (chemotaxis and Adhesion) Inducer Effect of GnRH-III Derivatives in Tetrahymena and Human Leukemia Cell Line Journal of Peptide Science : an Official Publication of the European Peptide Society. Jan, 2013 | Pubmed ID: 23208929 A Novel Cyclic RGD-containing Peptide Polymer Improves Serum-free Adhesion of Adipose Tissue-derived Mesenchymal Stem Cells to Bone Implant Surfaces Journal of Materials Science. Materials in Medicine. Feb, 2013 | Pubmed ID: 23135412 LGnRH-III -- a Promising Candidate for Anticancer Drug Development Protein and Peptide Letters. Apr, 2013 | Pubmed ID: 23016589 Enhanced Cellular Uptake and in Vitro Antitumor Activity of Short-chain Fatty Acid Acylated Daunorubicin-GnRH-III Bioconjugates European Journal of Medicinal Chemistry. Oct, 2012 | Pubmed ID: 22967796 Enhanced Cellular Uptake of a New, in Silico Identified Antitubercular Candidate by Peptide Conjugation Bioconjugate Chemistry. May, 2012 | Pubmed ID: 22515329 GnRH-III Based Multifunctional Drug Delivery Systems Containing Daunorubicin and Methotrexate European Journal of Medicinal Chemistry. Jun, 2012 | Pubmed ID: 22480495 In-vivo Antitumour Effect of Daunorubicin-GnRH-III Derivative Conjugates on Colon Carcinoma-bearing Mice Anti-cancer Drugs. Jan, 2012 | Pubmed ID: 21915040 Design, Synthesis, in Vitro Stability and Cytostatic Effect of Multifunctional Anticancer Drug-bioconjugates Containing GnRH-III As a Targeting Moiety Biopolymers. 2012 | Pubmed ID: 21509746 Isolation of Radial Glia-like Neural Stem Cells from Fetal and Adult Mouse Forebrain Via Selective Adhesion to a Novel Adhesive Peptide-conjugate PloS One. 2011 | Pubmed ID: 22163310 Anthracycline-GnRH Derivative Bioconjugates with Different Linkages: Synthesis, in Vitro Drug Release and Cytostatic Effect Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2011 | Pubmed ID: 21864594 Enhanced Enzymatic Stability and Antitumor Activity of Daunorubicin-GnRH-III Bioconjugates Modified in Position 4 Bioconjugate Chemistry. Jul, 2011 | Pubmed ID: 21668011 Syntheses and DNA Binding of New Cationic Porphyrin-tetrapeptide Conjugates Biophysical Chemistry. Apr, 2011 | Pubmed ID: 21402435 In Vitro Degradation and Antitumor Activity of Oxime Bond-linked Daunorubicin-GnRH-III Bioconjugates and DNA-binding Properties of Daunorubicin-amino Acid Metabolites Amino Acids. Jul, 2011 | Pubmed ID: 20953647 Efficient Synthesis of an (aminooxy) Acetylated-somatostatin Derivative Using (aminooxy)acetic Acid As a 'carbonyl Capture' Reagent Journal of Peptide Science : an Official Publication of the European Peptide Society. Jan, 2011 | Pubmed ID: 20812368 Daunomycin-polypeptide Conjugates with Antitumor Activity Biochimica Et Biophysica Acta. Dec, 2010 | Pubmed ID: 20659420 [Role of Iron Metabolism-regulator Hepcidin in Perinatal Iron Homeostasis] Orvosi Hetilap. Jan, 2010 | Pubmed ID: 20061265 Receptor-mediated Tumor Targeting Based on Peptide Hormones Expert Opinion on Drug Delivery. Jan, 2010 | Pubmed ID: 19947889 Luteinizing Hormone-releasing Hormone Antagonists Expert Opinion on Therapeutic Patents. Dec, 2009 | Pubmed ID: 19939192 Probing the Activity of Matrix Metalloproteinase II with a Sequentially Click-labeled Silica Nanoparticle FRET Probe Chembiochem : a European Journal of Chemical Biology. Sep, 2009 | Pubmed ID: 19637149 Interaction of Beta-amyloid(1-40) Peptide with Pairs of Metal Ions: An Electrospray Ion Trap Mass Spectrometric Model Study Biophysical Chemistry. Sep, 2009 | Pubmed ID: 19539421 Peptide Conjugates of Therapeutically Used Antitubercular Isoniazid-design, Synthesis and Antimycobacterial Effect Journal of Peptide Science : an Official Publication of the European Peptide Society. May, 2009 | Pubmed ID: 19319854 Matrix/analyte Ratio Influencing Polymer Molecular Weight Distribution in Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectrometry Rapid Communications in Mass Spectrometry : RCM. May, 2009 | Pubmed ID: 19306286 Development of an Oxime Bond Containing Daunorubicin-gonadotropin-releasing Hormone-III Conjugate As a Potential Anticancer Drug Bioconjugate Chemistry. Apr, 2009 | Pubmed ID: 19296605 Synthesis and Antibody Recognition of Cyclic Epitope Peptides, Together with Their Dimer and Conjugated Derivatives Based on Residues 9-22 of Herpes Simplex Virus Type 1 Glycoprotein D Bioconjugate Chemistry. Apr, 2009 | Pubmed ID: 19271736 Synthesis of Hepcidin Derivatives in Order to Develop Standards for Immune Adsorption Method Journal of Peptide Science : an Official Publication of the European Peptide Society. Apr, 2009 | Pubmed ID: 19189268 Dual Labeling of Biomolecules by Using Click Chemistry: a Sequential Approach Angewandte Chemie (International Ed. in English). 2009 | Pubmed ID: 19065684 Design, Synthesis, and in Vitro Activity of Novel Drug Delivery Systems Containing Tuftsin Derivatives and Methotrexate Bioconjugate Chemistry. Nov, 2008 | Pubmed ID: 18959436 New Derivatives of GnRH As Potential Anticancer Therapeutic Agents Current Medicinal Chemistry. 2008 | Pubmed ID: 18855666 Effect of Conjugation with Polypeptide Carrier on the Enzymatic Degradation of Herpes Simplex Virus Glycoprotein D Derived Epitope Peptide Bioconjugate Chemistry. Aug, 2008 | Pubmed ID: 18651758 In Vitro Cytotoxicity, Chemotactic Effect, and Cellular Uptake of Branched Polypeptides with Poly[L-lys] Backbone by J774 Murine Macrophage Cell Line Bioconjugate Chemistry. May, 2008 | Pubmed ID: 18429626 Antibody Recognition and Conformational Flexibility of a Plaque-specific Beta-amyloid Epitope Modulated by Non-native Peptide Flanking Regions Journal of Medicinal Chemistry. Mar, 2008 | Pubmed ID: 18284185 Design, Structural, and Immuno-analytical Properties of Antigenic Bioconjugates Comprising a Beta-amyloid-plaque Specific Epitope Biopolymers. 2008 | Pubmed ID: 18183582 Synthesis and Antibody Recognition of Synthetic Antigens from MUC1 Journal of Peptide Science : an Official Publication of the European Peptide Society. May, 2008 | Pubmed ID: 17975847 Mass Spectrometric Identification of the Trypsin Cleavage Pathway in Lysyl-proline Containing Oligotuftsin Peptides Journal of Peptide Science : an Official Publication of the European Peptide Society. Apr, 2007 | Pubmed ID: 17394121 Structure, Enzymatic Stability and Antitumor Activity of Sea Lamprey GnRH-III and Its Dimer Derivatives Peptides. Apr, 2007 | Pubmed ID: 17254668 Disulfide Bond Rearrangement During Regioselective Oxidation in PhS(O)Ph/CH3SiCl3 Mixture for the Synthesis of Alpha-conotoxin GI Biopolymers. 2007 | Pubmed ID: 17063467 Influence of Sequential Oligopeptide Carriers on the Bioactive Structure of Conjugated Epitopes: Comparative Study of the Conformation of a Herpes Simplex Virus Glycoprotein GD-1 Epitope in the Free and Conjugated Form, and Protein "built-in" Crystal Structure Biopolymers. 2006 | Pubmed ID: 16493659 Synthesis of Oligotuftsin-based Branched Oligopeptide Conjugates for Chemotactic Drug Targeting Journal of Peptide Science : an Official Publication of the European Peptide Society. May, 2006 | Pubmed ID: 16245264 Synthesis of Linear, Branched, and Cyclic Peptide Chimera Methods in Molecular Biology (Clifton, N.J.). 2005 | Pubmed ID: 16044540 Synthesis, Solution Conformation, and Antibody Recognition of Oligotuftsin-based Conjugates Containing a Beta-amyloid(4-10) Plaque-specific Epitope Bioconjugate Chemistry. Jul-Aug, 2005 | Pubmed ID: 16029033 The Effect of Cyclization on the Enzymatic Degradation of Herpes Simplex Virus Glycoprotein D Derived Epitope Peptide Journal of Peptide Science : an Official Publication of the European Peptide Society. Oct, 2005 | Pubmed ID: 15864815 Synthesis and Structural Characterization of Bioactive Peptide Conjugates Using Thioether Linkage Approaches Journal of Peptide Science : an Official Publication of the European Peptide Society. Dec, 2004 | Pubmed ID: 15635622 Polypeptide Conjugates Comprising a Beta-amyloid Plaque-specific Epitope As New Vaccine Structures Against Alzheimer's Disease Biopolymers. 2004 | Pubmed ID: 15499564 Natively Unfolded Tubulin Polymerization Promoting Protein TPPP/p25 is a Common Marker of Alpha-synucleinopathies Neurobiology of Disease. Nov, 2004 | Pubmed ID: 15474353 In Vitro T-cell Immunogenicity of Oligopeptides Derived from the Region 92-110 of the 16-kDa Protein of Mycobacterium Tuberculosis Biopolymers. 2004 | Pubmed ID: 15386261 Synthesis, Conformation, and Immunoreactivity of New Carrier Molecules Based on Repeated Tuftsin-like Sequence Biopolymers. Apr, 2004 | Pubmed ID: 15048768 Modeling of Main Characteristics of Bullous Pemphigoid Antigen-2 (BPAG2) Peptide Structure in Serological Recognition by Autoantibodies Pathology Oncology Research : POR. 2004 | Pubmed ID: 15029263 Synthesis and Comparison of Antibody Recognition of Conjugates Containing Herpes Simplex Virus Type 1 Glycoprotein D Epitope VII Bioconjugate Chemistry. Nov-Dec, 2003 | Pubmed ID: 14624643 Degranulation and Superoxide Production Depend on Cholesterol in PLB-985 Cells Biochemical and Biophysical Research Communications. Oct, 2003 | Pubmed ID: 14559248 Synthesis, Solution Structure Analysis and Antibody Binding of Cyclic Epitope Peptides from Glycoprotein D of Herpes Simplex Virus Type I Biophysical Chemistry. Nov, 2003 | Pubmed ID: 14556904 Drug Targeting by Macromolecules Without Recognition Unit? Journal of Molecular Recognition : JMR. Sep-Oct, 2003 | Pubmed ID: 14523942 Monitoring Folding Transitions of Synthetic, Branched-chain Polypeptides by Capillary Zone Electrophoresis Electrophoresis. Mar, 2003 | Pubmed ID: 12627439 Mass Spectrometric and Chemical Stability of the Asp-Pro Bond in Herpes Simplex Virus Epitope Peptides Compared with X-Pro Bonds of Related Sequences Journal of Peptide Science : an Official Publication of the European Peptide Society. Aug, 2002 | Pubmed ID: 12212803 Peptide Based Vaccine Design: Synthesis and Immunological Characterization of Branched Polypeptide Conjugates Comprising the 276-284 Immunodominant Epitope of HSV-1 Glycoprotein D Journal of Peptide Science : an Official Publication of the European Peptide Society. Mar, 2002 | Pubmed ID: 11931583 In Vitro Imaging and Quantification of the Drug Targeting Efficiency of Fluorescently Labeled GnRH Analogues József Murányi1,2, Attila Varga1, Bianka Gurbi1, Pál Gyulavári1, Gábor Mező3, Tibor Vántus2 1MTA-SE Pathobiochemistry Research Group, Semmelweis University, 2Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, 3MTA-ELTE Research Group of Peptide Chemistry, Eötvös Loránd University JoVE 55529 Cancer Research
In Vitro Imaging and Quantification of the Drug Targeting Efficiency of Fluorescently Labeled GnRH Analogues József Murányi1,2, Attila Varga1, Bianka Gurbi1, Pál Gyulavári1, Gábor Mező3, Tibor Vántus2 1MTA-SE Pathobiochemistry Research Group, Semmelweis University, 2Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, 3MTA-ELTE Research Group of Peptide Chemistry, Eötvös Loránd University JoVE 55529 Cancer Research
