Guang-Yu Yang Department of Pathology Northwestern University, Feinberg School of Medicine Biography Publications Institution JoVE Articles Guang-Yu Yang Guang-Yu Yang, MD, Ph. D is a physician-scientist and tenured professor who has had a longstanding and highly significant research interest in molecular carcinogenesis and cancer chemoprevention. He mainly focuses on oxylipin inflammatory signals, chronic inflammation-induced carcinogenesis and molecular carcinogenesis. Dr. Yang currently leads a large laboratory focusing on molecular carcinogenesis and cancer chemoprevention; he is funded with several NIH R01 grants as the principal investigator. Publications Unique Clinicopathologic and Genetic Alteration Features in Early Onset Colorectal Carcinoma Compared with Age-related Colorectal Carcinoma: a Large Cohort Next Generation Sequence Analysis Human Pathology. 11, 2020 | Pubmed ID: 32916163 Pathology in Patients with Chronic Liver Disease: A Practical Approach to Liver Biopsy Interpretation in Patients with Acute and Chronic Liver Diseases Clinics in Liver Disease. 08, 2020 | Pubmed ID: 32620277 Inhibition of Pancreatic Carcinoma Growth Through Enhancing ω-3 Epoxy Polyunsaturated Fatty Acid Profile by Inhibition of Soluble Epoxide Hydrolase Anticancer Research. Jul, 2019 | Pubmed ID: 31262891 Proinflammatory Enzyme Soluble Epoxide Hydrolase Bridges Obesity to Colonic Inflammation and Potential Carcinogenesis Proceedings of the National Academy of Sciences of the United States of America. 06, 2018 | Pubmed ID: 29769328 Inhibition of Chronic Pancreatitis and Murine Pancreatic Intraepithelial Neoplasia by a Dual Inhibitor of C-RAF and Soluble Epoxide Hydrolase in LSL-KrasG¹²D/Pdx-1-Cre Mice Anticancer Research. Jan, 2016 | Pubmed ID: 26722025 Inhibition of Mutant KrasG12D-initiated Murine Pancreatic Carcinoma Growth by a Dual C-Raf and Soluble Epoxide Hydrolase Inhibitor T-CUPM Cancer Letters. Feb, 2016 | Pubmed ID: 26683769 Composite Epstein-Barr Virus-Associated B-Cell Lymphoproliferative Disorder and Tubular Adenoma in a Rectal Polyp International Journal of Surgical Pathology. Feb, 2016 | Pubmed ID: 26353852 Molecular Characterization of Systemic Sclerosis Esophageal Pathology Identifies Inflammatory and Proliferative Signatures Arthritis Research & Therapy. Jul, 2015 | Pubmed ID: 26220546 Isolated Gallbladder Intramucosal Metastatic Melanoma With Features Mimicking Lymphoepithelial Carcinoma International Journal of Surgical Pathology. Aug, 2015 | Pubmed ID: 26041740 Concurrent Acute Necrotizing Adenovirus Hepatitis and Enterocolitis in an Adult Patient After Double Cord Blood Stem Cell Transplant for Refractory Crohn's Disease International Journal of Surgical Pathology. Aug, 2015 | Pubmed ID: 25998316 Knockdown or Inhibition of Aldo-keto Reductase 1B10 Inhibits Pancreatic Carcinoma Growth Via Modulating Kras-E-cadherin Pathway Cancer Letters. Dec, 2014 | Pubmed ID: 25304374 Unique Morphologic and Clinical Features of Liver Predominant/primary Small Cell Carcinoma--autopsy and Biopsy Case Series Annals of Diagnostic Pathology. Jun, 2014 | Pubmed ID: 24667053 Aldoketoreductase Family 1B10 (AKR1B10) As a Biomarker to Distinguish Hepatocellular Carcinoma from Benign Liver Lesions Human Pathology. Apr, 2014 | Pubmed ID: 24656094 Automated Dissection Protocol for Tumor Enrichment in Low Tumor Content Tissues Charles A. Havnar1, Oliver Zill2, Jeff Eastham1, Jeffrey Hung1, Manana Javey3, Emmanuel Naouri3, Jennifer Giltnane1, Justin M. Balko4, Andrew Wallace2, Nicolas Lounsbury2, Daniel Oreper2, Sarajane Saturnio1, G-Y Yang5, Amy A. Lo1 1Departments of Research Pathology, Genentech, 2Bioinformatics & Computational Biology, Genentech, 3Roche Sequencing Solutions, Hacienda Drive, 4Department of Medicine, Vanderbilt University Medical Center, Medical Center Drive, 5Department of Pathology, Northwestern University, Feinberg School of Medicine JoVE 62394 Cancer Research
Automated Dissection Protocol for Tumor Enrichment in Low Tumor Content Tissues Charles A. Havnar1, Oliver Zill2, Jeff Eastham1, Jeffrey Hung1, Manana Javey3, Emmanuel Naouri3, Jennifer Giltnane1, Justin M. Balko4, Andrew Wallace2, Nicolas Lounsbury2, Daniel Oreper2, Sarajane Saturnio1, G-Y Yang5, Amy A. Lo1 1Departments of Research Pathology, Genentech, 2Bioinformatics & Computational Biology, Genentech, 3Roche Sequencing Solutions, Hacienda Drive, 4Department of Medicine, Vanderbilt University Medical Center, Medical Center Drive, 5Department of Pathology, Northwestern University, Feinberg School of Medicine JoVE 62394 Cancer Research
