Gabriella Sozzi Department of Experimental Oncology and Molecular Medicine Fondazione IRCCS Istituto Nazionale dei Tumori Biography Publications Institution JoVE Articles Gabriella Sozzi has not added a biography. If you are Gabriella Sozzi and would like to personalize this page please email our Author Liaison for assistance. Publications Establishment of Patient Derived Xenografts As Functional Testing of Lung Cancer Aggressiveness Scientific Reports. Jul, 2017 | Pubmed ID: 28751748 Baseline and Postoperative C-reactive Protein Levels Predict Mortality in Operable Lung Cancer European Journal of Cancer (Oxford, England : 1990). Jul, 2017 | Pubmed ID: 28472743 Detection of MicroRNAs Using Chip-Based QuantStudio 3D Digital PCR Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 28439837 Inflammatory Status and Lung Function Predict Mortality in Lung Cancer Screening Participants European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP). Mar, 2017 | Pubmed ID: 28333763 Genomic Profiling of Patient-Derived Xenografts for Lung Cancer Identifies B2M Inactivation Impairing Immunorecognition Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2017 | Pubmed ID: 28302866 Mutational Profile from Targeted NGS Predicts Survival in LDCT Screening-Detected Lung Cancers Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. Jun, 2017 | Pubmed ID: 28302568 Mir-660-p53-mir-486 Network: A New Key Regulatory Pathway in Lung Tumorigenesis International Journal of Molecular Sciences. Jan, 2017 | Pubmed ID: 28124991 LKB1 Expression Correlates with Increased Survival in Patients with Advanced Non-Small Cell Lung Cancer Treated with Chemotherapy and Bevacizumab Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2017 | Pubmed ID: 28119362 Early Effector T Lymphocytes Coexpress Multiple Inhibitory Receptors in Primary Non-Small Cell Lung Cancer Cancer Research. Feb, 2017 | Pubmed ID: 27979840 Metabolic Evaluation of Non-Small Cell Lung Cancer Patient-Derived Xenograft Models Using 18F-FDG PET: A Potential Tool for Early Therapy Response Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jan, 2017 | Pubmed ID: 27765858 Lung Cancer Screening with Low-dose Spiral Computed Tomography: Evidence from a Pooled Analysis of Two Italian Randomized Trials European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP). Jul, 2017 | Pubmed ID: 27222939 GENOMIC PROFILING OF PATIENT-DERIVED XENOGRAFTS FOR LUNG CANCER IDENTIFIES B2M INACTIVATION IMPAIRING IMMUNORECOGNITION Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2016 | Pubmed ID: 28003304 CDCP1 is a Novel Marker of the Most Aggressive Human Triple-negative Breast Cancers Oncotarget. Oct, 2016 | Pubmed ID: 27626701 MicroRNA Profile of Lung Tumor Tissues Is Associated with a High Risk Plasma MiRNA Signature Microarrays (Basel, Switzerland). Jul, 2016 | Pubmed ID: 27600084 Anaplastic Lymphoma Kinase Aberrations Correlate with Metastatic Features in Pediatric Rhabdomyosarcoma Oncotarget. 09, 2016 | Pubmed ID: 27385213 Hepatocyte Growth Factor-mediated Satellite Cells Niche Perturbation Promotes Development of Distinct Sarcoma Subtypes ELife. Mar, 2016 | Pubmed ID: 26987019 [Lung Cancer Screening in High-risk Subjects: Early Detection with LDCT and Risk Stratification Using MiRNA-based Blood Test] Epidemiologia E Prevenzione. Jan-Feb, 2016 | Pubmed ID: 26951732 Stopping Smoking Reduces Mortality in Low-Dose Computed Tomography Screening Participants Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. May, 2016 | Pubmed ID: 26921675 Screening with Low-Dose Computed Tomography Does Not Improve Survival of Small Cell Lung Cancer Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. Feb, 2016 | Pubmed ID: 26845115 Synergistic Activation Upon MET and ALK Coamplification Sustains Targeted Therapy in Sarcomatoid Carcinoma, a Deadly Subtype of Lung Cancer Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. May, 2016 | Pubmed ID: 26804638 IL12RB2 Polymorphisms Correlate with Risk of Lung Adenocarcinoma Immunobiology. Feb, 2016 | Pubmed ID: 26547104 Conversion to Stem-cell State in Response to Microenvironmental Cues is Regulated by Balance Between Epithelial and Mesenchymal Features in Lung Cancer Cells Molecular Oncology. Feb, 2016 | Pubmed ID: 26514616 Novel Method to Detect MicroRNAs Using Chip-based QuantStudio 3D Digital PCR BMC Genomics. Oct, 2015 | Pubmed ID: 26493562 Circulating MicroRNA Signature As Liquid-biopsy to Monitor Lung Cancer in Low-dose Computed Tomography Screening Oncotarget. Oct, 2015 | Pubmed ID: 26451608 Gene Signatures Stratify Computed Tomography Screening Detected Lung Cancer in High-Risk Populations EBioMedicine. Aug, 2015 | Pubmed ID: 26425689 Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM- Lung Cancer-Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis Cancer Research. Sep, 2015 | Pubmed ID: 26141860 Combination Treatment with All-Trans Retinoic Acid Prevents Cisplatin-Induced Enrichment of CD133+ Tumor-Initiating Cells and Reveals Heterogeneity of Cancer Stem Cell Compartment in Lung Cancer Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. Jul, 2015 | Pubmed ID: 26020124 Recent Advances of MicroRNA-based Molecular Diagnostics to Reduce False-positive Lung Cancer Imaging Expert Review of Molecular Diagnostics. Jun, 2015 | Pubmed ID: 25924864 Potential Biomarkers for Lung Cancer Screening Translational Lung Cancer Research. Jun, 2014 | Pubmed ID: 25806293 Therapeutic Use of MicroRNAs in Lung Cancer BioMed Research International. 2014 | Pubmed ID: 25309923 Ewing Sarcoma of the Small Bowel: a Study of Seven Cases, Including One with the Uncommonly Reported EWSR1-FEV Translocation Histopathology. Jun, 2014 | Pubmed ID: 24898918 YAP1 Acts As Oncogenic Target of 11q22 Amplification in Multiple Cancer Subtypes Oncotarget. May, 2014 | Pubmed ID: 24810989 Assessment of Circulating MicroRNAs in Plasma of Lung Cancer Patients Molecules (Basel, Switzerland). Mar, 2014 | Pubmed ID: 24619302 Clinical Utility of a Plasma-based MiRNA Signature Classifier Within Computed Tomography Lung Cancer Screening: a Correlative MILD Trial Study Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2014 | Pubmed ID: 24419137 Predictors of Outcome in an AIEOP Series of Childhood Ependymomas: a Multifactorial Analysis Neuro-oncology. Nov, 2012 | Pubmed ID: 23076205 Multiparametric Molecular Characterization of Pulmonary Sarcomatoid Carcinoma Reveals a Nonrandom Amplification of Anaplastic Lymphoma Kinase (ALK) Gene Lung Cancer (Amsterdam, Netherlands). Sep, 2012 | Pubmed ID: 22705117 Role of MicroRNAs in Lung Cancer: MicroRNA Signatures in Cancer Prognosis Cancer Journal (Sudbury, Mass.). May-Jun, 2012 | Pubmed ID: 22647364 Patient-derived Xenografts of Non Small Cell Lung Cancer: Resurgence of an Old Model for Investigation of Modern Concepts of Tailored Therapy and Cancer Stem Cells Journal of Biomedicine & Biotechnology. 2012 | Pubmed ID: 22547927 Progressive Lung Cancer Determined by Expression Profiling and Transcriptional Regulation International Journal of Oncology. Jul, 2012 | Pubmed ID: 22469662 Annual or Biennial CT Screening Versus Observation in Heavy Smokers: 5-year Results of the MILD Trial European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP). May, 2012 | Pubmed ID: 22465911 Inactivation of Both FHIT and P53 Cooperate in Deregulating Proliferation-related Pathways in Lung Cancer Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. Apr, 2012 | Pubmed ID: 22425911 MicroRNAs and Lung Cancer: from Markers to Targets Cell Cycle (Georgetown, Tex.). Jul, 2011 | Pubmed ID: 21623159 MicroRNA Signatures in Tissues and Plasma Predict Development and Prognosis of Computed Tomography Detected Lung Cancer Proceedings of the National Academy of Sciences of the United States of America. Mar, 2011 | Pubmed ID: 21300873 Prognostic Determinants in Epithelioid Sarcoma European Journal of Cancer (Oxford, England : 1990). Jan, 2011 | Pubmed ID: 20932739 Treatment of Chondral Defects of the Knee with One Step Matrix-assisted Technique Enhanced by Autologous Concentrated Bone Marrow: in Vitro Characterisation of Mesenchymal Stem Cells from Iliac Crest and Subchondral Bone Injury. Nov, 2010 | Pubmed ID: 20934693 Molecular Cytogenetic Characterization of Stem-like Cancer Cells Isolated from Established Cell Lines Cancer Letters. Oct, 2010 | Pubmed ID: 20435407 Elevated Levels of the Acute-phase Serum Amyloid Are Associated with Heightened Lung Cancer Risk Cancer. Mar, 2010 | Pubmed ID: 20087959 Fluorodeoxyglucose Uptake Measured by Positron Emission Tomography and Standardized Uptake Value Predicts Long-term Survival of CT Screening Detected Lung Cancer in Heavy Smokers Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. Nov, 2009 | Pubmed ID: 19861905 Highly Tumorigenic Lung Cancer CD133+ Cells Display Stem-like Features and Are Spared by Cisplatin Treatment Proceedings of the National Academy of Sciences of the United States of America. Sep, 2009 | Pubmed ID: 19805294 Plasma DNA Levels in Spiral CT-detected and Clinically Detected Lung Cancer Patients: a Validation Analysis Lung Cancer (Amsterdam, Netherlands). Nov, 2009 | Pubmed ID: 19744743 The EML4-ALK Transcript but Not the Fusion Protein Can Be Expressed in Reactive and Neoplastic Lymphoid Tissues Haematologica. Sep, 2009 | Pubmed ID: 19734424 IL-12 Can Target Human Lung Adenocarcinoma Cells and Normal Bronchial Epithelial Cells Surrounding Tumor Lesions PloS One. Jul, 2009 | Pubmed ID: 19582164 Tumor-initiating Cells of HER2-positive Carcinoma Cell Lines Express the Highest Oncoprotein Levels and Are Sensitive to Trastuzumab Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2009 | Pubmed ID: 19276287 Prolonged Remission of Disseminated Atypical Adenomatous Hyperplasia Under Gefitinib Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. Feb, 2009 | Pubmed ID: 19179908 EML4-ALK Rearrangement in Non-small Cell Lung Cancer and Non-tumor Lung Tissues The American Journal of Pathology. Feb, 2009 | Pubmed ID: 19147828 Fragile Histidine Triad Gene Inactivation in Lung Cancer: the European Early Lung Cancer Project American Journal of Respiratory and Critical Care Medicine. Mar, 2009 | Pubmed ID: 19096006 Plasma DNA Quantification in Lung Cancer Computed Tomography Screening: Five-year Results of a Prospective Study American Journal of Respiratory and Critical Care Medicine. Jan, 2009 | Pubmed ID: 18787214 The Role of Chromosomal Alterations in Human Cancer Development Journal of Cellular Biochemistry. Oct, 2007 | Pubmed ID: 17722107 Radiation Effects on Development of HER2-positive Breast Carcinomas Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2007 | Pubmed ID: 17200337 Non-chromosome 11-p Syndromes in Wilms Tumor Patients: Clinical and Cytogenetic Report of Two Down Syndrome Cases and One Turner Syndrome Case American Journal of Medical Genetics. Part A. Jan, 2007 | Pubmed ID: 17163536 Fragile Histidine Triad Expression in Oral Squamous Cell Carcinoma and Precursor Lesions Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2006 | Pubmed ID: 17121892 Identification of Tumor-specific Molecular Signatures in Intracranial Ependymoma and Association with Clinical Characteristics Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Nov, 2006 | Pubmed ID: 17114655 Quantitative Analysis of Plasma DNA in Colorectal Cancer Patients: a Novel Prognostic Tool Annals of the New York Academy of Sciences. Sep, 2006 | Pubmed ID: 17108210 Salvage Treatment for Childhood Ependymoma After Surgery Only: Pitfalls of Omitting "at Once" Adjuvant Treatment International Journal of Radiation Oncology, Biology, Physics. Aug, 2006 | Pubmed ID: 16863927 Diadenosines As FHIT-ness Instructors Journal of Cellular Physiology. Aug, 2006 | Pubmed ID: 16547961 Detecting Cell-free Circulating HTERT MRNA in the Plasma May Identify a Subset of Nonsmall Cell Lung Cancer Patients Virchows Archiv : an International Journal of Pathology. Jan, 2006 | Pubmed ID: 16193293 Methylation Profile in Tumor and Sputum Samples of Lung Cancer Patients Detected by Spiral Computed Tomography: a Nested Case-control Study International Journal of Cancer. Mar, 2006 | Pubmed ID: 16152615 Effects of Prolonged Storage of Whole Plasma or Isolated Plasma DNA on the Results of Circulating DNA Quantification Assays Journal of the National Cancer Institute. Dec, 2005 | Pubmed ID: 16368947 Wilms Tumor in Monozygous Twins: Clinical, Pathological, Cytogenetic and Molecular Case Report Journal of Pediatric Hematology/oncology. Oct, 2005 | Pubmed ID: 16217254 SMARCB1/INI1 Tumor Suppressor Gene is Frequently Inactivated in Epithelioid Sarcomas Cancer Research. May, 2005 | Pubmed ID: 15899790 Reproducibility of a Semiquantitative Measurement of Circulating DNA in Plasma from Neoplastic Patients Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. May, 2005 | Pubmed ID: 15860889 Bilateral Preaxial Polydactyly in a WAGR Syndrome Patient American Journal of Medical Genetics. Part A. May, 2005 | Pubmed ID: 15742368 Reduced FEZ1/LZTS1 Expression and Outcome Prediction in Lung Cancer Cancer Research. Feb, 2005 | Pubmed ID: 15735004 The Apoptotic Pathway Triggered by the Fhit Protein in Lung Cancer Cell Lines is Not Affected by Bcl-2 or Bcl-x(L) Overexpression Oncogene. Dec, 2004 | Pubmed ID: 15489891 Genetic Alterations and in Vivo Tumorigenicity of Neurospheres Derived from an Adult Glioblastoma Molecular Cancer. Oct, 2004 | Pubmed ID: 15469606 Germline Mutations of the POU6F2 Gene in Wilms Tumors with Loss of Heterozygosity on Chromosome 7p14 Human Mutation. Nov, 2004 | Pubmed ID: 15459955 Dose-dependent Effect of FHIT-inducible Expression in Calu-1 Lung Cancer Cell Line Oncogene. Nov, 2004 | Pubmed ID: 15361849 Molecular Cytogenetic Characterization of Proximal-type Epithelioid Sarcoma Genes, Chromosomes & Cancer. Nov, 2004 | Pubmed ID: 15334553 Detecting Lung Cancer in Plasma with the Use of Multiple Genetic Markers International Journal of Cancer. Jan, 2004 | Pubmed ID: 14618621 Quantification of Free Circulating DNA As a Diagnostic Marker in Lung Cancer Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Nov, 2003 | Pubmed ID: 14507943 Evidence of Neural Differentiation in a Case of Post-therapy Primitive Neuroectodermal Tumor/Ewing Sarcoma of Bone The American Journal of Surgical Pathology. Aug, 2003 | Pubmed ID: 12883251 UQCRH Gene Encoding Mitochondrial Hinge Protein is Interrupted by a Translocation in a Soft-tissue Sarcoma and Epigenetically Inactivated in Some Cancer Cell Lines Oncogene. Jul, 2003 | Pubmed ID: 12881716 P16(INK4A) Hypermethylation Detected by Fluorescent Methylation-specific PCR in Plasmas from Non-small Cell Lung Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2002 | Pubmed ID: 12473590 Involvement of FHIT in Lung Carcinogenesis Prospects for Future Clinical Gene Therapy Applications I Supplementi Di Tumori : Official Journal of Societa Italiana Di Cancerologia ... [et Al.]. Jul-Aug, 2002 | Pubmed ID: 12415825 Molecular Changes Track Recurrence and Progression of Bronchial Precancerous Lesions Lung Cancer (Amsterdam, Netherlands). Sep, 2002 | Pubmed ID: 12234694 Restoration of Fragile Histidine Triad (FHIT) Expression Induces Apoptosis and Suppresses Tumorigenicity in Lung and Cervical Cancer Cell Lines Proceedings of the National Academy of Sciences of the United States of America. Mar, 2002 | Pubmed ID: 11891319 基于 rna 的液体活检: 血浆 miRNA 特征分类器 (MSC) 在肺癌筛查中的经验 Mavis Mensah*1, Cristina Borzi*1, Carla Verri1, Paola Suatoni2, Davide Conte1, Ugo Pastorino2, Fortunato Orazio1, Gabriella Sozzi1, Mattia Boeri1 1Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, 2Unit of Thoracic Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori JoVE 56326 Cancer Research
基于 rna 的液体活检: 血浆 miRNA 特征分类器 (MSC) 在肺癌筛查中的经验 Mavis Mensah*1, Cristina Borzi*1, Carla Verri1, Paola Suatoni2, Davide Conte1, Ugo Pastorino2, Fortunato Orazio1, Gabriella Sozzi1, Mattia Boeri1 1Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, 2Unit of Thoracic Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori JoVE 56326 Cancer Research