Galit Alter Massachusetts General Hospital Ragon Institute of MGH, MIT, and Harvard Biography Publications Institution JoVE Articles Galit Alter has not added a biography. If you are Galit Alter and would like to personalize this page please email our Author Liaison for assistance. Publications Emerging Concepts on the Role of Innate Immunity in the Prevention and Control of HIV Infection Annual Review of Medicine. Feb, 2012 | Pubmed ID: 22077718 Copy Number Variation of KIR Genes Influences HIV-1 Control PLoS Biology. Nov, 2011 | Pubmed ID: 22140359 KIR/HLA: Genetic Clues for a Role of NK Cells in the Control of HIV Advances in Experimental Medicine and Biology. 2011 | Pubmed ID: 21842362 HIV-1 Adaptation to NK-cell-mediated Immune Pressure Nature. Aug, 2011 | Pubmed ID: 21814282 Early Viral Replication in Lymph Nodes Provides HIV with a Means by Which to Escape NK-cell-mediated Control European Journal of Immunology. Sep, 2011 | Pubmed ID: 21630248 Decreased Fc Receptor Expression on Innate Immune Cells is Associated with Impaired Antibody-mediated Cellular Phagocytic Activity in Chronically HIV-1 Infected Individuals Virology. Jul, 2011 | Pubmed ID: 21565376 KIR Polymorphisms Modulate Peptide-dependent Binding to an MHC Class I Ligand with a Bw6 Motif PLoS Pathogens. Mar, 2011 | Pubmed ID: 21423672 Mutiny or Scrutiny: NK Cell Modulation of DC Function in HIV-1 Infection Trends in Immunology. May, 2011 | Pubmed ID: 21411368 Natural Killer Cells in Spontaneous Control of HIV Infection Current Opinion in HIV and AIDS. May, 2011 | Pubmed ID: 21399495 Characteristics of the Earliest Cross-neutralizing Antibody Response to HIV-1 PLoS Pathogens. 2011 | Pubmed ID: 21249232 Expansion of 2B4+ Natural Killer (NK) Cells and Decrease in NKp46+ NK Cells in Response to Influenza Immunology. Apr, 2011 | Pubmed ID: 21214542 A Robust, High-throughput Assay to Determine the Phagocytic Activity of Clinical Antibody Samples Journal of Immunological Methods. Mar, 2011 | Pubmed ID: 21192942 Reduced Frequencies of NKp30+NKp46+, CD161+, and NKG2D+ NK Cells in Acute HCV Infection May Predict Viral Clearance Journal of Hepatology. Aug, 2011 | Pubmed ID: 21168454 Comprehensive Analysis of Virus-specific T-cells Provides Clues for the Failure of Therapeutic Immunization with ALVAC-HIV Vaccine AIDS (London, England). Jan, 2011 | Pubmed ID: 21076273 Determinants of Protection Among HIVâ€exposed Seronegative Persons: an Overview The Journal of Infectious Diseases. Nov, 2010 | Pubmed ID: 20887220 The Humoral Response to HIV-1: New Insights, Renewed Focus The Journal of Infectious Diseases. Oct, 2010 | Pubmed ID: 20846039 MHC Class I Chain-related Protein A Shedding in Chronic HIV-1 Infection is Associated with Profound NK Cell Dysfunction Virology. Oct, 2010 | Pubmed ID: 20667578 IL-10 Induces Aberrant Deletion of Dendritic Cells by Natural Killer Cells in the Context of HIV Infection The Journal of Clinical Investigation. Jun, 2010 | Pubmed ID: 20440075 Alterations in Natural Killer Cell Receptor Profiles During HIV Type 1 Disease Progression Among Chronically Infected South African Adults AIDS Research and Human Retroviruses. Apr, 2010 | Pubmed ID: 20380481 Challenges Facing Young Investigators IAVI Report : Newsletter on International AIDS Vaccine Research. Jan-Feb, 2009 | Pubmed ID: 20214278 Sex Differences in the Toll-like Receptor-mediated Response of Plasmacytoid Dendritic Cells to HIV-1 Nature Medicine. Aug, 2009 | Pubmed ID: 19597505 Matrix Metalloprotease Inhibitors Restore Impaired NK Cell-mediated Antibody-dependent Cellular Cytotoxicity in Human Immunodeficiency Virus Type 1 Infection Journal of Virology. Sep, 2009 | Pubmed ID: 19553339 HLA Class I Subtype-dependent Expansion of KIR3DS1+ and KIR3DL1+ NK Cells During Acute Human Immunodeficiency Virus Type 1 Infection Journal of Virology. Jul, 2009 | Pubmed ID: 19386717 Report on the AIDS Vaccine 2008 Conference Human Vaccines. Mar, 2009 | Pubmed ID: 19202348 Protective HLA Class I Alleles That Restrict Acute-phase CD8+ T-cell Responses Are Associated with Viral Escape Mutations Located in Highly Conserved Regions of Human Immunodeficiency Virus Type 1 Journal of Virology. Feb, 2009 | Pubmed ID: 19036810 Type 2 Bias of T Cells Expanded from the Blood of Melanoma Patients Switched to Type 1 by IL-12p70 MRNA-transfected Dendritic Cells Cancer Research. Nov, 2008 | Pubmed ID: 19010919 Rapid Loss of Dendritic Cell and Monocyte Responses to TLR Ligands Following Venipuncture Journal of Immunological Methods. Dec, 2008 | Pubmed ID: 18848564 Ligand-independent Exhaustion of Killer Immunoglobulin-like Receptor-positive CD8+ T Cells in Human Immunodeficiency Virus Type 1 Infection Journal of Virology. Oct, 2008 | Pubmed ID: 18579582 Antigen Load and Viral Sequence Diversification Determine the Functional Profile of HIV-1-specific CD8+ T Cells PLoS Medicine. May, 2008 | Pubmed ID: 18462013 Novel KIR3DL1 Alleles and Their Expression Levels on NK Cells: Convergent Evolution of KIR3DL1 Phenotype Variation? Journal of Immunology (Baltimore, Md. : 1950). May, 2008 | Pubmed ID: 18453594 Upregulation of PD-L1 on Monocytes and Dendritic Cells by HIV-1 Derived TLR Ligands AIDS (London, England). Mar, 2008 | Pubmed ID: 18317010 Rapid Ex Vivo Isolation and Long-term Culture of Human Th17 Cells Journal of Immunological Methods. Apr, 2008 | Pubmed ID: 18314131 Biology of Plasmacytoid Dendritic Cells and Natural Killer Cells in HIV-1 Infection Current Opinion in HIV and AIDS. May, 2007 | Pubmed ID: 19372886 Differential Natural Killer Cell-mediated Inhibition of HIV-1 Replication Based on Distinct KIR/HLA Subtypes The Journal of Experimental Medicine. Nov, 2007 | Pubmed ID: 18025129 Detection of KIR3DS1 on the Cell Surface of Peripheral Blood NK Cells Facilitates Identification of a Novel Null Allele and Assessment of KIR3DS1 Expression During HIV-1 Infection Journal of Immunology (Baltimore, Md. : 1950). Aug, 2007 | Pubmed ID: 17641029 Single-stranded RNA Derived from HIV-1 Serves As a Potent Activator of NK Cells Journal of Immunology (Baltimore, Md. : 1950). Jun, 2007 | Pubmed ID: 17548602 MyD88-dependent Immune Activation Mediated by Human Immunodeficiency Virus Type 1-encoded Toll-like Receptor Ligands Journal of Virology. Aug, 2007 | Pubmed ID: 17507480 Recognition of a Defined Region Within P24 Gag by CD8+ T Cells During Primary Human Immunodeficiency Virus Type 1 Infection in Individuals Expressing Protective HLA Class I Alleles Journal of Virology. Jul, 2007 | Pubmed ID: 17494064 Evolution of Innate and Adaptive Effector Cell Functions During Acute HIV-1 Infection The Journal of Infectious Diseases. May, 2007 | Pubmed ID: 17436225 Perspective Natural Killer Cells: Bridging Innate and Adaptive Immunity? IAVI Report : Newsletter on International AIDS Vaccine Research. May-Jun, 2006 | Pubmed ID: 20217934 HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response Against HIV-1 PLoS Medicine. Oct, 2006 | Pubmed ID: 17076553 NK Cell Function in HIV-1 Infection Current Molecular Medicine. Sep, 2006 | Pubmed ID: 17022732 Immunological and Virological Impact of Highly Active Antiretroviral Therapy Initiated During Acute HIV-1 Infection The Journal of Infectious Diseases. Sep, 2006 | Pubmed ID: 16941338 Low Perforin and Elevated SHIP-1 Expression is Associated with Functional Anergy of Natural Killer Cells in Chronic HIV-1 Infection AIDS (London, England). Jul, 2006 | Pubmed ID: 16847410 Consistent Effects of TSG101 Genetic Variability on Multiple Outcomes of Exposure to Human Immunodeficiency Virus Type 1 Journal of Virology. Jul, 2006 | Pubmed ID: 16809281 De Novo Generation of Escape Variant-specific CD8+ T-cell Responses Following Cytotoxic T-lymphocyte Escape in Chronic Human Immunodeficiency Virus Type 1 Infection Journal of Virology. Oct, 2005 | Pubmed ID: 16188997 High Degree of Inter-clade Cross-reactivity of HIV-1-specific T Cell Responses at the Single Peptide Level AIDS (London, England). Sep, 2005 | Pubmed ID: 16135897 Sequential Deregulation of NK Cell Subset Distribution and Function Starting in Acute HIV-1 Infection Blood. Nov, 2005 | Pubmed ID: 16002429 The Majority of Currently Circulating Human Immunodeficiency Virus Type 1 Clade B Viruses Fail to Prime Cytotoxic T-lymphocyte Responses Against an Otherwise Immunodominant HLA-A2-restricted Epitope: Implications for Vaccine Design Journal of Virology. Apr, 2005 | Pubmed ID: 15795285 Human Immunodeficiency Virus (HIV)-specific Gamma Interferon Secretion Directed Against All Expressed HIV Genes: Relationship to Rate of CD4 Decline Journal of Virology. Apr, 2005 | Pubmed ID: 15795276 CD107a As a Functional Marker for the Identification of Natural Killer Cell Activity Journal of Immunological Methods. Nov, 2004 | Pubmed ID: 15604012 Assessment of Longitudinal Changes in HIV-specific Effector Activity in Subjects Undergoing Untreated Primary HIV Infection AIDS (London, England). Oct, 2004 | Pubmed ID: 15577619 Increased Natural Killer Cell Activity in Viremic HIV-1 Infection Journal of Immunology (Baltimore, Md. : 1950). Oct, 2004 | Pubmed ID: 15470077 Loss of HIV-1-specific CD8+ T Cell Proliferation After Acute HIV-1 Infection and Restoration by Vaccine-induced HIV-1-specific CD4+ T Cells The Journal of Experimental Medicine. Sep, 2004 | Pubmed ID: 15381726 HIV-1-specific Cytotoxicity is Preferentially Mediated by a Subset of CD8(+) T Cells Producing Both Interferon-gamma and Tumor Necrosis Factor-alpha Blood. Jul, 2004 | Pubmed ID: 15059848 Human Immunodeficiency Virus (HIV)-specific Effector CD8 T Cell Activity in Patients with Primary HIV Infection The Journal of Infectious Diseases. Mar, 2002 | Pubmed ID: 11920293 קביעת פעילות Phagocytic דוגמאות של נוגדן קלינית Elizabeth G. McAndrew1, Anne-Sophie Dugast1, Anna F. Licht1, Justin R. Eusebio1, Galit Alter1, Margaret E. Ackerman2 1Massachusetts General Hospital, Ragon Institute of MGH, MIT, and Harvard, 2Thayer School of Engineering, Dartmouth College JoVE 3588 Immunology and Infection
קביעת פעילות Phagocytic דוגמאות של נוגדן קלינית Elizabeth G. McAndrew1, Anne-Sophie Dugast1, Anna F. Licht1, Justin R. Eusebio1, Galit Alter1, Margaret E. Ackerman2 1Massachusetts General Hospital, Ragon Institute of MGH, MIT, and Harvard, 2Thayer School of Engineering, Dartmouth College JoVE 3588 Immunology and Infection