Other Publications (1)
Articles by Gary F. Hammen in JoVE
Ex vivo Tilberedninger af den intakte Vomeronasal orgel og tilbehør lugtekolben Wayne I. Doyle1, Gary F. Hammen2, Julian P. Meeks1 1Department of Neuroscience, UT Southwestern Medical Center, 2Department of Anatomy and Neurobiology, Washington University in St. Louis Musen tilbehør lugtekolben (AOB) har været vanskeligt at studere i forbindelse med sensoriske kodning. Her viser vi en dissektion, der producerer en ex vivo præparat, hvori AOB neuroner forbliver funktionelt forbundet til deres perifere indgange, lette forskning i behandling af oplysninger af muse feromoner og kairomones.
Other articles by Gary F. Hammen on PubMed
Functional Organization of Glomerular Maps in the Mouse Accessory Olfactory Bulb Nature Neuroscience. Jul, 2014 | Pubmed ID: 24880215 The mammalian accessory olfactory system extracts information about species, sex and individual identity from social odors, but its functional organization remains unclear. We imaged presynaptic Ca(2+) signals in vomeronasal inputs to the accessory olfactory bulb (AOB) during peripheral stimulation using light sheet microscopy. Urine- and steroid-responsive glomeruli densely innervated the anterior AOB. Glomerular activity maps for sexually mature female mouse urine overlapped maps for juvenile and/or gonadectomized urine of both sexes, whereas maps for sexually mature male urine were highly distinct. Further spatial analysis revealed a complicated organization involving selective juxtaposition and dispersal of functionally grouped glomerular classes. Glomeruli that were similarly tuned to urines were often closely associated, whereas more disparately tuned glomeruli were selectively dispersed. Maps to a panel of sulfated steroid odorants identified tightly juxtaposed groups that were disparately tuned and dispersed groups that were similarly tuned. These results reveal a modular, nonchemotopic spatial organization in the AOB.