Other Publications (1)
Articles by Gary F. Hammen in JoVE
Ex vivo la Producción de la Bombilla órgano vomeronasal y accesorios olfativa Intacto Wayne I. Doyle1, Gary F. Hammen2, Julian P. Meeks1 1Department of Neuroscience, UT Southwestern Medical Center, 2Department of Anatomy and Neurobiology, Washington University in St. Louis El bulbo olfativo accesorio ratón (AOB) ha sido difícil de estudiar en el contexto de la codificación sensorial. Este sentido, demuestran una disección que produce un vivo preparación ex en el que las neuronas AOB permanecen funcionalmente conectados a sus entradas de periferia, facilitando la investigación sobre el procesamiento de información de las feromonas del ratón y kairomones.
Other articles by Gary F. Hammen on PubMed
Functional Organization of Glomerular Maps in the Mouse Accessory Olfactory Bulb Nature Neuroscience. Jul, 2014 | Pubmed ID: 24880215 The mammalian accessory olfactory system extracts information about species, sex and individual identity from social odors, but its functional organization remains unclear. We imaged presynaptic Ca(2+) signals in vomeronasal inputs to the accessory olfactory bulb (AOB) during peripheral stimulation using light sheet microscopy. Urine- and steroid-responsive glomeruli densely innervated the anterior AOB. Glomerular activity maps for sexually mature female mouse urine overlapped maps for juvenile and/or gonadectomized urine of both sexes, whereas maps for sexually mature male urine were highly distinct. Further spatial analysis revealed a complicated organization involving selective juxtaposition and dispersal of functionally grouped glomerular classes. Glomeruli that were similarly tuned to urines were often closely associated, whereas more disparately tuned glomeruli were selectively dispersed. Maps to a panel of sulfated steroid odorants identified tightly juxtaposed groups that were disparately tuned and dispersed groups that were similarly tuned. These results reveal a modular, nonchemotopic spatial organization in the AOB.