Geerten P. van Nieuw Amerongen

Publications

• Regulation of the Endothelial Barrier Function: a Filum Granum of Cellular Forces, Rho-GTPase Signaling and Microenvironment
  Cell and Tissue Research. Mar, 2014  |   Pubmed ID: 24633925
• Plasma Biomarkers for Acute Respiratory Distress Syndrome: a Systematic Review and Meta-analysis*
  Critical Care Medicine. Mar, 2014  |   Pubmed ID: 24158164
• Reversal of Vascular Leak with Imatinib
  American Journal of Respiratory and Critical Care Medicine. Nov, 2013  |   Pubmed ID: 24180451
• Localized RhoA GTPase Activity Regulates Dynamics of Endothelial Monolayer Integrity
  Cardiovascular Research. Aug, 2013  |   Pubmed ID: 23536606
• Effective Treatment of Edema and Endothelial Barrier Dysfunction with Imatinib
  Circulation. Dec, 2012  |   Pubmed ID: 23099479
• Successful Treatment of Diffuse Pulmonary Lymphangiomatosis with Bevacizumab
  Annals of Internal Medicine. Jun, 2012  |   Pubmed ID: 22665821
• Nitric Oxide-dependent Src Activation and Resultant Caveolin-1 Phosphorylation Promote ENOS/caveolin-1 Binding and ENOS Inhibition
  Molecular Biology of the Cell. Apr, 2012  |   Pubmed ID: 22323292
• Predictors of Pulmonary Edema Formation During Fluid Loading in the Critically Ill with Presumed Hypovolemia*
  Critical Care Medicine. Mar, 2012  |   Pubmed ID: 22080639
• Homocysteine Induces Phosphatidylserine Exposure in Cardiomyocytes Through Inhibition of Rho Kinase and Flippase Activity
  Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2011  |   Pubmed ID: 21865848
• Opposing Effects of the Angiopoietins on the Thrombin-induced Permeability of Human Pulmonary Microvascular Endothelial Cells
  PloS One. 2011  |   Pubmed ID: 21858121
• Plasma Protein Levels Are Markers of Pulmonary Vascular Permeability and Degree of Lung Injury in Critically Ill Patients with or at Risk for Acute Lung Injury/acute Respiratory Distress Syndrome
  Critical Care Medicine. Jan, 2011  |   Pubmed ID: 21057316
• Substrate Stiffening Promotes Endothelial Monolayer Disruption Through Enhanced Physical Forces
  American Journal of Physiology. Cell Physiology. Jan, 2011  |   Pubmed ID: 20861463
• Fibrin β15-42 Domain is Cryptic in Intact Fibrinogen: Comment on the Study by A. Sahni Et Al
  International Journal of Cancer. Journal International Du Cancer. Dec, 2010  |   Pubmed ID: 21351277
• Inhibition of Rho-ROCK Signaling Induces Apoptotic and Non-apoptotic PS Exposure in Cardiomyocytes Via Inhibition of Flippase
  Journal of Molecular and Cellular Cardiology. Nov, 2010  |   Pubmed ID: 20691698
• A Plethora of Angiopoietin-2 Effects During Clinical Sepsis
  Critical Care (London, England). 2010  |   Pubmed ID: 20587077
• Role of Protein Kinase Czeta in Thrombin-induced RhoA Activation and Inter-endothelial Gap Formation of Human Dermal Microvessel Endothelial Cell Monolayers
  Microvascular Research. Sep, 2010  |   Pubmed ID: 20417648
• Activation of AMP-activated Protein Kinase by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside in the Muscle Microcirculation Increases Nitric Oxide Synthesis and Microvascular Perfusion
  Arteriosclerosis, Thrombosis, and Vascular Biology. Jun, 2010  |   Pubmed ID: 20224051
• Driving Rho GTPase Activity in Endothelial Cells Regulates Barrier Integrity
  Thrombosis and Haemostasis. Jan, 2010  |   Pubmed ID: 20062930
• KLF2-induced Actin Shear Fibers Control Both Alignment to Flow and JNK Signaling in Vascular Endothelium
  Blood. Mar, 2010  |   Pubmed ID: 20032497
• The Interaction of Soluble Tie2 with Angiopoietins and Pulmonary Vascular Permeability in Septic and Nonseptic Critically Ill Patients
  Shock (Augusta, Ga.). Mar, 2010  |   Pubmed ID: 19543148
• Activated Protein C in the Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome
  Expert Opinion on Drug Discovery. Mar, 2009  |   Pubmed ID: 23489122
• Circulating Angiopoietin-2 Levels in the Course of Septic Shock: Relation with Fluid Balance, Pulmonary Dysfunction and Mortality
  Intensive Care Medicine. Sep, 2009  |   Pubmed ID: 19551369
• Endothelin Receptor Blockade Combined with Phosphodiesterase-5 Inhibition Increases Right Ventricular Mitochondrial Capacity in Pulmonary Arterial Hypertension
  American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2009  |   Pubmed ID: 19395550
• RhoA-ROCK Signaling is Involved in Contraction-mediated Inhibition of SERCA2a Expression in Cardiomyocytes
  Pflügers Archiv : European Journal of Physiology. Aug, 2009  |   Pubmed ID: 19294414
• Crystalloid or Colloid Fluid Loading and Pulmonary Permeability, Edema, and Injury in Septic and Nonseptic Critically Ill Patients with Hypovolemia
  Critical Care Medicine. Apr, 2009  |   Pubmed ID: 19242338
• Role of ROCK I/II in Vascular Branching
  American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2009  |   Pubmed ID: 19218507
• The Angiopoietin-Tie2 System As a Therapeutic Target in Sepsis and Acute Lung Injury
  Expert Opinion on Therapeutic Targets. Jan, 2009  |   Pubmed ID: 19063705
• Interference with Actin Dynamics is Superior to Disturbance of Microtubule Function in the Inhibition of Human Ovarian Cancer Cell Motility
  Biochemical Pharmacology. Sep, 2008  |   Pubmed ID: 18644348
• Nuclear Targeting of Beta-catenin and P120ctn During Thrombin-induced Endothelial Barrier Dysfunction
  Cardiovascular Research. Sep, 2008  |   Pubmed ID: 18490349
• Rho-kinase-dependent F-actin Rearrangement is Involved in the Inhibition of PI3-kinase/Akt During Ischemia-reperfusion-induced Endothelial Cell Apoptosis
  Apoptosis : an International Journal on Programmed Cell Death. Mar, 2008  |   Pubmed ID: 18165899
• Endogenous RhoA Inhibitor Protects Endothelial Barrier
  Circulation Research. Jul, 2007  |   Pubmed ID: 17615376
• Microtubule-targeting Agents Inhibit Angiogenesis at Subtoxic Concentrations, a Process Associated with Inhibition of Rac1 and Cdc42 Activity and Changes in the Endothelial Cytoskeleton
  Molecular Cancer Therapeutics. Sep, 2006  |   Pubmed ID: 16985069
• Direct Grafting of RGD-motif-containing Peptide on the Surface of Polycaprolactone Films
  Journal of Biomaterials Science. Polymer Edition. 2006  |   Pubmed ID: 16800155
• Physiological Concentrations of Insulin Induce Endothelin-dependent Vasoconstriction of Skeletal Muscle Resistance Arteries in the Presence of Tumor Necrosis Factor-alpha Dependence on C-Jun N-terminal Kinase
  Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2006  |   Pubmed ID: 16322532
• Vascular Endothelial Growth Factor Overexpression in Ischemic Skeletal Muscle Enhances Myoglobin Expression in Vivo
  Circulation Research. Jul, 2004  |   Pubmed ID: 15155530
• Vasoconstrictor Effects of Insulin in Skeletal Muscle Arterioles Are Mediated by ERK1/2 Activation in Endothelium
  American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2004  |   Pubmed ID: 15059773
• GIT1 Mediates Thrombin Signaling in Endothelial Cells: Role in Turnover of RhoA-type Focal Adhesions
  Circulation Research. Apr, 2004  |   Pubmed ID: 15016733
• Smooth Muscle F-actin Disassembly and RhoA/Rho-kinase Signaling During Endotoxin-induced Alterations in Pulmonary Arterial Compliance
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Oct, 2004  |   Pubmed ID: 14514519
• Involvement of RhoA/Rho Kinase Signaling in VEGF-induced Endothelial Cell Migration and Angiogenesis in Vitro
  Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2003  |   Pubmed ID: 12588761
• Targets for Pharmacological Intervention of Endothelial Hyperpermeability and Barrier Function
  Vascular Pharmacology. Nov, 2002  |   Pubmed ID: 12747965
• Endothelial Hyperpermeability in Vascular Leakage
  Vascular Pharmacology. Nov, 2002  |   Pubmed ID: 12747957
• Intracellular Signalling Involved in Modulating Human Endothelial Barrier Function
  Journal of Anatomy. Jun, 2002  |   Pubmed ID: 12162723