Geoffrey Chupp

Publications

• Phenotypes and Endotypes of Adult Asthma: Moving Toward Precision Medicine
  The Journal of Allergy and Clinical Immunology. Jul, 2019  |   Pubmed ID: 31277742
• Rapid Onset of Effect of Benralizumab on Morning Peak Expiratory Flow in Severe, Uncontrolled Asthma
  Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology. May, 2019  |   Pubmed ID: 30802500
• Pulmonary Artery Pseudoaneurysm Causing Massive Hemoptysis in Hyperimmunoglobulin E Syndrome: a Case Report
  BMC Pulmonary Medicine. Feb, 2019  |   Pubmed ID: 30736787
• Bronchial Thermoplasty
  Clinics in Chest Medicine. Mar, 2019  |   Pubmed ID: 30691712
• Building an Informed Consent Tool Starting with the Patient: The Patient-Centered Virtual Multimedia Interactive Informed Consent (VIC)
  AMIA ... Annual Symposium Proceedings. AMIA Symposium. 2017  |   Pubmed ID: 29854101
• Characterisation of Asthma Subgroups Associated with Circulating YKL-40 Levels
  The European Respiratory Journal. 10, 2017  |   Pubmed ID: 29025889
• Long-term Outcomes of Bronchial Thermoplasty in Subjects with Severe Asthma: a Comparison of 3-year Follow-up Results from Two Prospective Multicentre Studies
  The European Respiratory Journal. 08, 2017  |   Pubmed ID: 28860266
• Reappraisal of the Clinical Effect of Mepolizumab - Authors' Reply
  The Lancet. Respiratory Medicine. 06, 2017  |   Pubmed ID: 28664853
• Efficacy of Mepolizumab Add-on Therapy on Health-related Quality of Life and Markers of Asthma Control in Severe Eosinophilic Asthma (MUSCA): a Randomised, Double-blind, Placebo-controlled, Parallel-group, Multicentre, Phase 3b Trial
  The Lancet. Respiratory Medicine. 05, 2017  |   Pubmed ID: 28395936
• Multiparameter Single Cell Profiling of Airway Inflammatory Cells
  Cytometry. Part B, Clinical Cytometry. 01, 2017  |   Pubmed ID: 27807928
• Sputum Gene Expression of IL-13 Receptor α2 Chain Correlates with Airflow Obstruction and Helper T-Cell Type 2 Inflammation in Asthma
  Annals of the American Thoracic Society. Mar, 2016  |   Pubmed ID: 27027964
• Asthma Characteristics and Biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) Longitudinal Profiling Study
  Respiratory Research. Nov, 2015  |   Pubmed ID: 26576744
• Noninvasive Analysis of the Sputum Transcriptome Discriminates Clinical Phenotypes of Asthma
  American Journal of Respiratory and Critical Care Medicine. May, 2015  |   Pubmed ID: 25763605
• Chitinase 3-like-1 Regulates Both Visceral Fat Accumulation and Asthma-like Th2 Inflammation
  American Journal of Respiratory and Critical Care Medicine. Apr, 2015  |   Pubmed ID: 25629580
• Genetic Variation in Chitinase 3-like 1 (CHI3L1) Contributes to Asthma Severity and Airway Expression of YKL-40
  The Journal of Allergy and Clinical Immunology. Jul, 2015  |   Pubmed ID: 25592985
• IL-6 Receptor α Defines Effector Memory CD8+ T Cells Producing Th2 Cytokines and Expanding in Asthma
  American Journal of Respiratory and Critical Care Medicine. Dec, 2014  |   Pubmed ID: 25390970
• Role of Growth Arrest-specific Gene 6 in the Development of Fungal Allergic Airway Disease in Mice
  American Journal of Respiratory Cell and Molecular Biology. Nov, 2014  |   Pubmed ID: 24810144
• Improvement in Asthma Control and Inflammation in Children Undergoing Adenotonsillectomy
  Pediatric Research. Mar, 2014  |   Pubmed ID: 24452590
• Segmental Allergen Challenge Enhances Chitinase Activity and Levels of CCL18 in Mild Atopic Asthma
  Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology. Feb, 2013  |   Pubmed ID: 23331560
• Chitinase-like Protein Brp-39/YKL-40 Modulates the Renal Response to Ischemic Injury and Predicts Delayed Allograft Function
  Journal of the American Society of Nephrology : JASN. Feb, 2013  |   Pubmed ID: 23291472
• Targeting ST2L Potentiates CpG-mediated Therapeutic Effects in a Chronic Fungal Asthma Model
  The American Journal of Pathology. Jul, 2011  |   Pubmed ID: 21640974
• Role of Breast Regression Protein-39 in the Pathogenesis of Cigarette Smoke-induced Inflammation and Emphysema
  American Journal of Respiratory Cell and Molecular Biology. Jun, 2011  |   Pubmed ID: 20656949
• The Chitinase and Chitinase-like Proteins: a Review of Genetic and Functional Studies in Asthma and Immune-mediated Diseases
  Current Opinion in Allergy and Clinical Immunology. Oct, 2009  |   Pubmed ID: 19644363
• Novel Biomarkers in Asthma: Chemokines and Chitinase-like Proteins
  Current Opinion in Allergy and Clinical Immunology. Feb, 2009  |   Pubmed ID: 19532094
• Role of Breast Regression Protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced Tissue Responses and Apoptosis
  The Journal of Experimental Medicine. May, 2009  |   Pubmed ID: 19414556
• A Chitinase-like Protein in the Lung and Circulation of Patients with Severe Asthma
  The New England Journal of Medicine. Nov, 2007  |   Pubmed ID: 18003958
• IL-18 is Induced and IL-18 Receptor Alpha Plays a Critical Role in the Pathogenesis of Cigarette Smoke-induced Pulmonary Emphysema and Inflammation
  Journal of Immunology (Baltimore, Md. : 1950). Feb, 2007  |   Pubmed ID: 17237446
• Hyperoxia Causes Angiopoietin 2-mediated Acute Lung Injury and Necrotic Cell Death
  Nature Medicine. Nov, 2006  |   Pubmed ID: 17086189
• Transgenic Modeling of Transforming Growth Factor-beta(1): Role of Apoptosis in Fibrosis and Alveolar Remodeling
  Proceedings of the American Thoracic Society. Jul, 2006  |   Pubmed ID: 16799085
• Asthma: Mechanisms of Disease Persistence and Progression
  Annual Review of Immunology. 2004  |   Pubmed ID: 15032597
• Reactive Oxygen Species and Extracellular Signal-regulated Kinase 1/2 Mitogen-activated Protein Kinase Mediate Hyperoxia-induced Cell Death in Lung Epithelium
  American Journal of Respiratory Cell and Molecular Biology. Mar, 2003  |   Pubmed ID: 12594056
• IL-13 Stimulates Vascular Endothelial Cell Growth Factor and Protects Against Hyperoxic Acute Lung Injury
  The Journal of Clinical Investigation. Sep, 2000  |   Pubmed ID: 10995789
• Airway Remodeling in Asthma
  The Journal of Clinical Investigation. Oct, 1999  |   Pubmed ID: 10525034
• Tissue and T Cell Distribution of Precursor and Mature IL-16
  Journal of Immunology (Baltimore, Md. : 1950). Sep, 1998  |   Pubmed ID: 9743378