George A. O'Toole Department of Microbiology & Immunology Geisel School of Medicine at Dartmouth Biography Publications Institution JoVE Articles George A. O'Toole has not added a biography. If you are George A. O'Toole and would like to personalize this page please email our Author Liaison for assistance. Publications The Gut-Lung Axis in Cystic Fibrosis Journal of Bacteriology. Aug, 2021 | Pubmed ID: 34339302 Biochemical and Structural Characterization of Two Cif-like Epoxide Hydrolases from Current Research in Structural Biology. 2021 | Pubmed ID: 34235487 Mild Cystic Fibrosis Lung Disease Is Associated with Bacterial Community Stability Microbiology Spectrum. Jul, 2021 | Pubmed ID: 34232099 Interaction Between the Type 4 Pili Machinery and a Diguanylate Cyclase Fine-tune C-di-GMP Levels During Early Biofilm Formation Proceedings of the National Academy of Sciences of the United States of America. Jun, 2021 | Pubmed ID: 34168081 One Versus Many: Polymicrobial Communities and the Cystic Fibrosis Airway MBio. 03, 2021 | Pubmed ID: 33727344 Characterization of Ciprofloxacin Resistance Levels: Implications for Ototopical Therapy Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 08, 2021 | Pubmed ID: 33710149 Metabolic Modeling to Interrogate Microbial Disease: A Tale for Experimentalists Frontiers in Molecular Biosciences. 2021 | Pubmed ID: 33681294 Uses C-di-GMP Phosphodiesterases RmcA and MorA To Regulate Biofilm Maintenance MBio. 02, 2021 | Pubmed ID: 33531388 Roadmap on Emerging Concepts in the Physical Biology of Bacterial Biofilms: from Surface Sensing to Community Formation Physical Biology. Jun, 2021 | Pubmed ID: 33462162 Identification of Cell-surface Glycans That Mediate Motility-dependent Binding and Internalization of Pseudomonas Aeruginosa by Phagocytes Molecular Immunology. 03, 2021 | Pubmed ID: 33358569 Aerosolized Drug-loaded Nanoparticles Targeting Migration Inhibitory Factors Inhibit -induced Inflammation and Biofilm Formation Nanomedicine (London, England). 12, 2020 | Pubmed ID: 33241979 Discovering the Molecular Determinants of Phaeobacter Inhibens Susceptibility to Phaeobacter Phage MD18 MSphere. 11, 2020 | Pubmed ID: 33148823 From Input to Output: The Lap/c-di-GMP Biofilm Regulatory Circuit Annual Review of Microbiology. 09, 2020 | Pubmed ID: 32689917 Pseudomonas Aeruginosa PA14 Enhances the Efficacy of Norfloxacin Against Staphylococcus Aureus Newman Biofilms Journal of Bacteriology. 08, 2020 | Pubmed ID: 32661077 MapA, a Second Large RTX Adhesin Conserved Across the Pseudomonads, Contributes to Biofilm Formation by Pseudomonas Fluorescens Journal of Bacteriology. 08, 2020 | Pubmed ID: 32631946 Age and Environmental Exposures Influence the Fecal Bacteriome of Young Children with Cystic Fibrosis Pediatric Pulmonology. 07, 2020 | Pubmed ID: 32275127 Lung Function and Microbiota Diversity in Cystic Fibrosis Microbiome. 04, 2020 | Pubmed ID: 32238195 Social Cooperativity of Bacteria During Reversible Surface Attachment in Young Biofilms: a Quantitative Comparison of Pseudomonas Aeruginosa PA14 and PAO1 MBio. 02, 2020 | Pubmed ID: 32098815 Exogenous Alginate Protects Staphylococcus Aureus from Killing by Pseudomonas Aeruginosa Journal of Bacteriology. Mar, 2020 | Pubmed ID: 31792010 Availability of Zinc Impacts Interactions Between Streptococcus Sanguinis and Pseudomonas Aeruginosa in Coculture Journal of Bacteriology. 01, 2020 | Pubmed ID: 31685535 Gross Transcriptomic Analysis of Pseudomonas Putida for Diagnosing Environmental Shifts Microbial Biotechnology. 01, 2020 | Pubmed ID: 30957409 Interspecies Interactions Induce Exploratory Motility in ELife. 11, 2019 | Pubmed ID: 31713513 Lying in Wait: Modeling the Control of Bacterial Infections Via Antibiotic-Induced Proviruses MSystems. Oct, 2019 | Pubmed ID: 31575664 "It Takes a Village": Mechanisms Underlying Antimicrobial Recalcitrance of Polymicrobial Biofilms Journal of Bacteriology. 12, 2019 | Pubmed ID: 31548277 Glycocluster Tetrahydroxamic Acids Exhibiting Unprecedented Inhibition of Biofilms Journal of Medicinal Chemistry. 09, 2019 | Pubmed ID: 31449405 Special Meeting Issue for the 8th ASM Conference on Biofilms Journal of Bacteriology. 09, 2019 | Pubmed ID: 31439756 Pseudomonas Aeruginosa Increases the Sensitivity of Biofilm-Grown Staphylococcus Aureus to Membrane-Targeting Antiseptics and Antibiotics MBio. 07, 2019 | Pubmed ID: 31363032 Altered Stool Microbiota of Infants with Cystic Fibrosis Shows a Reduction in Genera Associated with Immune Programming from Birth Journal of Bacteriology. 08, 2019 | Pubmed ID: 31209076 Bordetella Bronchiseptica Diguanylate Cyclase BdcA Regulates Motility and Is Important for the Establishment of Respiratory Infection in Mice Journal of Bacteriology. 09, 2019 | Pubmed ID: 31209073 Metabolic Modeling of Cystic Fibrosis Airway Communities Predicts Mechanisms of Pathogen Dominance MSystems. Mar-Apr, 2019 | Pubmed ID: 31020043 The Yin and Yang of Lung Infections in Cystic Fibrosis: a Model for Studying Polymicrobial Interactions Journal of Bacteriology. 06, 2019 | Pubmed ID: 30885933 Pseudomonas Aeruginosa Can Inhibit Growth of Streptococcal Species Via Siderophore Production Journal of Bacteriology. 04, 2019 | Pubmed ID: 30718303 Flagellar Stators Stimulate C-di-GMP Production by Pseudomonas Aeruginosa Journal of Bacteriology. 09, 2019 | Pubmed ID: 30642992 Co-opting the Lap System of Pseudomonas Fluorescens To Reversibly Customize Bacterial Cell Surfaces ACS Synthetic Biology. 11, 2018 | Pubmed ID: 30278125 Ligand-Mediated Biofilm Formation Via Enhanced Physical Interaction Between a Diguanylate Cyclase and Its Receptor MBio. 07, 2018 | Pubmed ID: 29991582 Special Sections for the 6th ASM Conference on Cell-Cell Communication in Bacteria Journal of Bacteriology. 07, 2018 | Pubmed ID: 29941545 Type 1 Does the Two-Step: Type 1 Secretion Substrates with a Functional Periplasmic Intermediate Journal of Bacteriology. 09, 2018 | Pubmed ID: 29866808 Multigenerational Memory and Adaptive Adhesion in Early Bacterial Biofilm Communities Proceedings of the National Academy of Sciences of the United States of America. 04, 2018 | Pubmed ID: 29559526 An N-Terminal Retention Module Anchors the Giant Adhesin LapA of Pseudomonas Fluorescens at the Cell Surface: a Novel Subfamily of Type I Secretion Systems Journal of Bacteriology. 04, 2018 | Pubmed ID: 29437852 A Multimodal Strategy Used by a Large C-di-GMP Network Journal of Bacteriology. 04, 2018 | Pubmed ID: 29311282 Cystic Fibrosis Airway Microbiome: Overturning the Old, Opening the Way for the New Journal of Bacteriology. 02, 2018 | Pubmed ID: 29084859 Special Meeting Sections for the ASM Conference on Mechanisms of Interbacterial Cooperation and Competition Journal of Bacteriology. 11, 2017 | Pubmed ID: 29042432 An Antipersister Strategy for Treatment of Chronic Pseudomonas Aeruginosa Infections Antimicrobial Agents and Chemotherapy. Dec, 2017 | Pubmed ID: 28923873 High-Speed "4D" Computational Microscopy of Bacterial Surface Motility ACS Nano. 09, 2017 | Pubmed ID: 28836761 Alters Staphylococcus Sensitivity to Vancomycin in a Biofilm Model of Cystic Fibrosis Infection MBio. 07, 2017 | Pubmed ID: 28720732 Special Meeting Sections for the 6th ASM Conference on Beneficial Microbes Journal of Bacteriology. 08, 2017 | Pubmed ID: 28698224 A Symphony of Cyclases: Specificity in Diguanylate Cyclase Signaling Annual Review of Microbiology. 09, 2017 | Pubmed ID: 28645224 Classic Spotlights: Selected Highlights from the First 100 Years of the Journal of Bacteriology. 07, 2017 | Pubmed ID: 28611240 Pseudomonas Aeruginosa-Derived Rhamnolipids and Other Detergents Modulate Colony Morphotype and Motility in the Burkholderia Cepacia Complex Journal of Bacteriology. 07, 2017 | Pubmed ID: 28439038 Alginate Overproduction Promotes Coexistence with in a Model of Cystic Fibrosis Respiratory Infection MBio. 03, 2017 | Pubmed ID: 28325763 Bacteria, Rev Your Engines: Stator Dynamics Regulate Flagellar Motility Journal of Bacteriology. 06, 2017 | Pubmed ID: 28320878 Role of Cyclic Di-GMP and Exopolysaccharide in Type IV Pilus Dynamics Journal of Bacteriology. 04, 2017 | Pubmed ID: 28167523 Special Meeting Sections Journal of Bacteriology. 01, 2016 | Pubmed ID: 28588069 Classic Spotlight: How the Gram Stain Works Journal of Bacteriology. 12, 2016 | Pubmed ID: 27815540 Classic Spotlight: Plate Counting You Can Count On Journal of Bacteriology. 12, 2016 | Pubmed ID: 27815539 Classic Spotlight: Bacteroides Thetaiotaomicron, Starch Utilization, and the Birth of the Microbiome Era Journal of Bacteriology. 10, 2016 | Pubmed ID: 27660335 Special Meeting Sections for the 7th ASM Conference on Biofilms Journal of Bacteriology. 10, 2016 | Pubmed ID: 27613861 Requirements for Pseudomonas Aeruginosa Type I-F CRISPR-Cas Adaptation Determined Using a Biofilm Enrichment Assay Journal of Bacteriology. 11, 2016 | Pubmed ID: 27573013 Cyanide Toxicity to Burkholderia Cenocepacia Is Modulated by Polymicrobial Communities and Environmental Factors Frontiers in Microbiology. 2016 | Pubmed ID: 27242743 Classic Spotlight: Cyclic Di-GMP, the Molecule That Makes the Bacterial World Stop Going 'Round Journal of Bacteriology. 06, 2016 | Pubmed ID: 27179064 PilZ Domain Protein FlgZ Mediates Cyclic Di-GMP-Dependent Swarming Motility Control in Pseudomonas Aeruginosa Journal of Bacteriology. 07, 2016 | Pubmed ID: 27114465 The Inhibitory Site of a Diguanylate Cyclase Is a Necessary Element for Interaction and Signaling with an Effector Protein Journal of Bacteriology. 06, 2016 | Pubmed ID: 27002135 Sensational Biofilms: Surface Sensing in Bacteria Current Opinion in Microbiology. Apr, 2016 | Pubmed ID: 26968016 Friendly Fire: Biological Functions and Consequences of Chromosomal Targeting by CRISPR-Cas Systems Journal of Bacteriology. 05, 2016 | Pubmed ID: 26929301 Species-dependent Hydrodynamics of Flagellum-tethered Bacteria in Early Biofilm Development Journal of the Royal Society, Interface. Feb, 2016 | Pubmed ID: 26864892 Classic Spotlight: Quorum Sensing and the Multicellular Life of Unicellular Organisms Journal of Bacteriology. Feb, 2016 | Pubmed ID: 26825965 Classic Spotlight: Before They Were Biofilms Journal of Bacteriology. 01, 2016 | Pubmed ID: 26668270 Tobramycin-Treated Pseudomonas Aeruginosa PA14 Enhances Streptococcus Constellatus 7155 Biofilm Formation in a Cystic Fibrosis Model System Journal of Bacteriology. 01, 2016 | Pubmed ID: 26483523 Cyclic Di-GMP-Regulated Periplasmic Proteolysis of a Pseudomonas Aeruginosa Type Vb Secretion System Substrate Journal of Bacteriology. 01, 2016 | Pubmed ID: 26100041 Cystic Fibrosis Lung Infections: Polymicrobial, Complex, and Hard to Treat PLoS Pathogens. Dec, 2015 | Pubmed ID: 26719892 Iron-dependent Gene Expression in Actinomyces Oris Journal of Oral Microbiology. 2015 | Pubmed ID: 26685151 Contribution of Physical Interactions to Signaling Specificity Between a Diguanylate Cyclase and Its Effector MBio. Dec, 2015 | Pubmed ID: 26670387 Mannitol Does Not Enhance Tobramycin Killing of Pseudomonas Aeruginosa in a Cystic Fibrosis Model System of Biofilm Formation PloS One. 2015 | Pubmed ID: 26506004 C-di-GMP and Its Effects on Biofilm Formation and Dispersion: a Pseudomonas Aeruginosa Review Microbiology Spectrum. Apr, 2015 | Pubmed ID: 26104694 Haemophilus Influenzae Responds to Glucocorticoids Used in Asthma Therapy by Modulation of Biofilm Formation and Antibiotic Resistance EMBO Molecular Medicine. Aug, 2015 | Pubmed ID: 25995336 Clustered Regularly Interspaced Short Palindromic Repeat-Dependent, Biofilm-Specific Death of Pseudomonas Aeruginosa Mediated by Increased Expression of Phage-Related Genes MBio. May, 2015 | Pubmed ID: 25968642 Coculture of Staphylococcus Aureus with Pseudomonas Aeruginosa Drives S. Aureus Towards Fermentative Metabolism and Reduced Viability in a Cystic Fibrosis Model Journal of Bacteriology. Jul, 2015 | Pubmed ID: 25917910 Associations Between Gut Microbial Colonization in Early Life and Respiratory Outcomes in Cystic Fibrosis The Journal of Pediatrics. Jul, 2015 | Pubmed ID: 25818499 A Hierarchical Cascade of Second Messengers Regulates Pseudomonas Aeruginosa Surface Behaviors MBio. Jan, 2015 | Pubmed ID: 25626906 Characterization and Quantification of the Fungal Microbiome in Serial Samples from Individuals with Cystic Fibrosis Microbiome. 2014 | Pubmed ID: 25408892 Surface Attachment Induces Pseudomonas Aeruginosa Virulence Proceedings of the National Academy of Sciences of the United States of America. Nov, 2014 | Pubmed ID: 25385640 Candida Albicans Ethanol Stimulates Pseudomonas Aeruginosa WspR-controlled Biofilm Formation As Part of a Cyclic Relationship Involving Phenazines PLoS Pathogens. Oct, 2014 | Pubmed ID: 25340349 Mechanistic Insight into the Conserved Allosteric Regulation of Periplasmic Proteolysis by the Signaling Molecule Cyclic-di-GMP ELife. Sep, 2014 | Pubmed ID: 25182848 Epoxide-mediated Differential Packaging of Cif and Other Virulence Factors into Outer Membrane Vesicles Journal of Bacteriology. Oct, 2014 | Pubmed ID: 25112474 The Microbiome in Pediatric Cystic Fibrosis Patients: the Role of Shared Environment Suggests a Window of Intervention Microbiome. 2014 | Pubmed ID: 25071935 The Microbiota Regulates Susceptibility to Fas-mediated Acute Hepatic Injury Laboratory Investigation; a Journal of Technical Methods and Pathology. Sep, 2014 | Pubmed ID: 25068658 Structural Features of the Pseudomonas Fluorescens Biofilm Adhesin LapA Required for LapG-dependent Cleavage, Biofilm Formation, and Cell Surface Localization Journal of Bacteriology. Aug, 2014 | Pubmed ID: 24837291 Plate-based Assay for Swarming Motility in Pseudomonas Aeruginosa Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24818898 Plate-based Assay for Swimming Motility in Pseudomonas Aeruginosa Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24818897 Micro-patterned Surfaces Reduce Bacterial Colonization and Biofilm Formation in Vitro: Potential for Enhancing Endotracheal Tube Designs Clinical and Translational Medicine. 2014 | Pubmed ID: 24739529 Deletion Mutant Library for Investigation of Functional Outputs of Cyclic Diguanylate Metabolism in Pseudomonas Aeruginosa PA14 Applied and Environmental Microbiology. Jun, 2014 | Pubmed ID: 24657857 Single-cell and Single-molecule Analysis Deciphers the Localization, Adhesion, and Mechanics of the Biofilm Adhesin LapA ACS Chemical Biology. Feb, 2014 | Pubmed ID: 24556201 Pseudomonas Aeruginosa Flagellar Motility Activates the Phagocyte PI3K/Akt Pathway to Induce Phagocytic Engulfment American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2014 | Pubmed ID: 24487390 Signature Motifs Identify an Acinetobacter Cif Virulence Factor with Epoxide Hydrolase Activity The Journal of Biological Chemistry. Mar, 2014 | Pubmed ID: 24474692 Single-molecule Analysis of Pseudomonas Fluorescens Footprints ACS Nano. Feb, 2014 | Pubmed ID: 24456070 Synthesis of Bioinspired Carbohydrate Amphiphiles That Promote and Inhibit Biofilms Chemical Science (Royal Society of Chemistry : 2010). Feb, 2014 | Pubmed ID: 24376911 Iron Supplementation Does Not Worsen Respiratory Health or Alter the Sputum Microbiome in Cystic Fibrosis Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. May, 2014 | Pubmed ID: 24332997 Unique Microbial Communities Persist in Individual Cystic Fibrosis Patients Throughout a Clinical Exacerbation Microbiome. Nov, 2013 | Pubmed ID: 24451123 Pouring Salt on a Wound: Pseudomonas Aeruginosa Virulence Factors Alter Na+ and Cl- Flux in the Lung Journal of Bacteriology. Sep, 2013 | Pubmed ID: 23836869 Eradication of Pseudomonas Aeruginosa Biofilms on Cultured Airway Cells by a Fosfomycin/tobramycin Antibiotic Combination Pathogens and Disease. Feb, 2013 | Pubmed ID: 23620118 Cyclic-di-GMP Signalling Regulates Motility and Biofilm Formation in Bordetella Bronchiseptica Microbiology (Reading, England). May, 2013 | Pubmed ID: 23475948 Atomic Force and Super-resolution Microscopy Support a Role for LapA As a Cell-surface Biofilm Adhesin of Pseudomonas Fluorescens Research in Microbiology. Nov-Dec, 2012 | Pubmed ID: 23064158 Second Messenger Regulation of Biofilm Formation: Breakthroughs in Understanding C-di-GMP Effector Systems Annual Review of Cell and Developmental Biology. 2012 | Pubmed ID: 23057745 The CRISPR/Cas Adaptive Immune System of Pseudomonas Aeruginosa Mediates Resistance to Naturally Occurring and Engineered Phages Journal of Bacteriology. Nov, 2012 | Pubmed ID: 22885297 Iron Homeostasis During Cystic Fibrosis Pulmonary Exacerbation Clinical and Translational Science. Aug, 2012 | Pubmed ID: 22883617 Epoxide-mediated CifR Repression of Cif Gene Expression Utilizes Two Binding Sites in Pseudomonas Aeruginosa Journal of Bacteriology. Oct, 2012 | Pubmed ID: 22843844 In Vitro Evaluation of Tobramycin and Aztreonam Versus Pseudomonas Aeruginosa Biofilms on Cystic Fibrosis-derived Human Airway Epithelial Cells The Journal of Antimicrobial Chemotherapy. Nov, 2012 | Pubmed ID: 22843834 Does the F508-CFTR Mutation Induce a Proinflammatory Response in Human Airway Epithelial Cells? American Journal of Physiology. Lung Cellular and Molecular Physiology. Sep, 2012 | Pubmed ID: 22821996 LapG, Required for Modulating Biofilm Formation by Pseudomonas Fluorescens Pf0-1, is a Calcium-dependent Protease Journal of Bacteriology. Aug, 2012 | Pubmed ID: 22707708 Structural Characterization of a Conserved, Calcium-dependent Periplasmic Protease from Legionella Pneumophila Journal of Bacteriology. Aug, 2012 | Pubmed ID: 22707706 Diphosphonium Ionic Liquids As Broad-Spectrum Antimicrobial Agents Cornea. Jan, 2012 | Pubmed ID: 22236790 Bacterial Cis-2-unsaturated Fatty Acids Found in the Cystic Fibrosis Airway Modulate Virulence and Persistence of Pseudomonas Aeruginosa The ISME Journal. Dec, 2011 | Pubmed ID: 22134647 Exploiting Dendrimer Multivalency To Combat Emerging and Re-Emerging Infectious Diseases Molecular Pharmaceutics. Dec, 2011 | Pubmed ID: 22126461 2-Heptyl-4-quinolone, a Precursor of the Pseudomonas Quinolone Signal Molecule, Modulates Swarming Motility in Pseudomonas Aeruginosa Journal of Bacteriology. Dec, 2011 | Pubmed ID: 21965567 Step-wise Loss of Bacterial Flagellar Torsion Confers Progressive Phagocytic Evasion PLoS Pathogens. Sep, 2011 | Pubmed ID: 21949654 Systematic Analysis of Diguanylate Cyclases That Promote Biofilm Formation by Pseudomonas Fluorescens Pf0-1 Journal of Bacteriology. Sep, 2011 | Pubmed ID: 21764921 Modulation of Pseudomonas Aeruginosa Surface-associated Group Behaviors by Individual Amino Acids Through C-di-GMP Signaling Research in Microbiology. Sep, 2011 | Pubmed ID: 21554951 A Pseudomonas Aeruginosa Toxin That Hijacks the Host Ubiquitin Proteolytic System PLoS Pathogens. Mar, 2011 | Pubmed ID: 21455491 Non-identity-mediated CRISPR-bacteriophage Interaction Mediated Via the Csy and Cas3 Proteins Journal of Bacteriology. Jul, 2011 | Pubmed ID: 21398535 Structural Basis for C-di-GMP-mediated Inside-out Signaling Controlling Periplasmic Proteolysis PLoS Biology. 2011 | Pubmed ID: 21304926 A C-di-GMP Effector System Controls Cell Adhesion by Inside-out Signaling and Surface Protein Cleavage PLoS Biology. 2011 | Pubmed ID: 21304920 Aminoglycoside Resistance of Pseudomonas Aeruginosa Biofilms Modulated by Extracellular Polysaccharide International Microbiology : the Official Journal of the Spanish Society for Microbiology. Dec, 2010 | Pubmed ID: 21404215 Specific Control of Pseudomonas Aeruginosa Surface-associated Behaviors by Two C-di-GMP Diguanylate Cyclases MBio. 2010 | Pubmed ID: 20978535 Staphylococcus Aureus Resistance on Titanium Coated with Multivalent PEGylated-peptides Biomaterials. Dec, 2010 | Pubmed ID: 20863561 Pseudomonas Aeruginosa Evasion of Phagocytosis is Mediated by Loss of Swimming Motility and is Independent of Flagellum Expression Infection and Immunity. Jul, 2010 | Pubmed ID: 20457788 Antibodies and Immune Effectors: Shaping Gram-negative Bacterial Phenotypes Trends in Microbiology. Jun, 2010 | Pubmed ID: 20359893 Cyclic-di-GMP-mediated Repression of Swarming Motility by Pseudomonas Aeruginosa: the PilY1 Gene and Its Impact on Surface-associated Behaviors Journal of Bacteriology. Jun, 2010 | Pubmed ID: 20233936 Di-adenosine Tetraphosphate (Ap4A) Metabolism Impacts Biofilm Formation by Pseudomonas Fluorescens Via Modulation of C-di-GMP-dependent Pathways Journal of Bacteriology. Jun, 2010 | Pubmed ID: 20154123 Crystal Structure of the Cystic Fibrosis Transmembrane Conductance Regulator Inhibitory Factor Cif Reveals Novel Active-site Features of an Epoxide Hydrolase Virulence Factor Journal of Bacteriology. Apr, 2010 | Pubmed ID: 20118260 Sugar Fatty Acid Esters Inhibit Biofilm Formation by Food-borne Pathogenic Bacteria International Journal of Food Microbiology. Mar, 2010 | Pubmed ID: 20089325 The Pseudomonas Aeruginosa Magnesium Transporter MgtE Inhibits Transcription of the Type III Secretion System Infection and Immunity. Mar, 2010 | Pubmed ID: 20028803 Flagellum-mediated Biofilm Defense Mechanisms of Pseudomonas Aeruginosa Against Host-derived Lactoferrin Infection and Immunity. Oct, 2009 | Pubmed ID: 19651866 Directed Assembly of PEGylated-peptide Coatings for Infection-resistant Titanium Metal Journal of the American Chemical Society. Aug, 2009 | Pubmed ID: 19621876 New Yeast Recombineering Tools for Bacteria Plasmid. Sep, 2009 | Pubmed ID: 19477196 Long-distance Delivery of Bacterial Virulence Factors by Pseudomonas Aeruginosa Outer Membrane Vesicles PLoS Pathogens. Apr, 2009 | Pubmed ID: 19360133 LapD is a Bis-(3',5')-cyclic Dimeric GMP-binding Protein That Regulates Surface Attachment by Pseudomonas Fluorescens Pf0-1 Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009 | Pubmed ID: 19218451 Tobramycin and FDA-approved Iron Chelators Eliminate Pseudomonas Aeruginosa Biofilms on Cystic Fibrosis Cells American Journal of Respiratory Cell and Molecular Biology. Sep, 2009 | Pubmed ID: 19168700 The Developmental Model of Microbial Biofilms: Ten Years of a Paradigm Up for Review Trends in Microbiology. Feb, 2009 | Pubmed ID: 19162483 Interaction Between Bacteriophage DMS3 and Host CRISPR Region Inhibits Group Behaviors of Pseudomonas Aeruginosa Journal of Bacteriology. Jan, 2009 | Pubmed ID: 18952788 Chemotoxicity of Doxorubicin and Surface Expression of P-glycoprotein (MDR1) is Regulated by the Pseudomonas Aeruginosa Toxin Cif American Journal of Physiology. Cell Physiology. Sep, 2008 | Pubmed ID: 18650266 Cif is Negatively Regulated by the TetR Family Repressor CifR Infection and Immunity. Jul, 2008 | Pubmed ID: 18458065 The DeltaF508-CFTR Mutation Results in Increased Biofilm Formation by Pseudomonas Aeruginosa by Increasing Iron Availability American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2008 | Pubmed ID: 18359885 Genetic Evidence for an Alternative Citrate-dependent Biofilm Formation Pathway in Staphylococcus Aureus That is Dependent on Fibronectin Binding Proteins and the GraRS Two-component Regulatory System Infection and Immunity. Jun, 2008 | Pubmed ID: 18347039 Pseudomonas Aeruginosa Biofilm Formation in the Cystic Fibrosis Airway Pulmonary Pharmacology & Therapeutics. Aug, 2008 | Pubmed ID: 18234534 In Vitro Analysis of Tobramycin-treated Pseudomonas Aeruginosa Biofilms on Cystic Fibrosis-derived Airway Epithelial Cells Infection and Immunity. Apr, 2008 | Pubmed ID: 18212077 In Vivo Growth of Pseudomonas Aeruginosa Strains PAO1 and PA14 and the Hypervirulent Strain LESB58 in a Rat Model of Chronic Lung Infection Journal of Bacteriology. Apr, 2008 | Pubmed ID: 18083816 The Flagellum of Pseudomonas Aeruginosa is Required for Resistance to Clearance by Surfactant Protein A PloS One. 2007 | Pubmed ID: 17593964 SadC Reciprocally Influences Biofilm Formation and Swarming Motility Via Modulation of Exopolysaccharide Production and Flagellar Function Journal of Bacteriology. Nov, 2007 | Pubmed ID: 17586642 BifA, a Cyclic-Di-GMP Phosphodiesterase, Inversely Regulates Biofilm Formation and Swarming Motility by Pseudomonas Aeruginosa PA14 Journal of Bacteriology. Nov, 2007 | Pubmed ID: 17586641 Roles for Flagellar Stators in Biofilm Formation by Pseudomonas Aeruginosa Research in Microbiology. Jun, 2007 | Pubmed ID: 17533122 The Pseudomonas Aeruginosa Secreted Protein PA2934 Decreases Apical Membrane Expression of the Cystic Fibrosis Transmembrane Conductance Regulator Infection and Immunity. Aug, 2007 | Pubmed ID: 17502391 Inverse Regulation of Biofilm Formation and Swarming Motility by Pseudomonas Aeruginosa PA14 Journal of Bacteriology. May, 2007 | Pubmed ID: 17337585 Phosphate-dependent Modulation of C-di-GMP Levels Regulates Pseudomonas Fluorescens Pf0-1 Biofilm Formation by Controlling Secretion of the Adhesin LapA Molecular Microbiology. Feb, 2007 | Pubmed ID: 17302799 Vulnerability of Pathogenic Biofilms to Micavibrio Aeruginosavorus Applied and Environmental Microbiology. Jan, 2007 | Pubmed ID: 17098913 Peptide-PEG Amphiphiles As Cytophobic Coatings for Mammalian and Bacterial Cells Chemistry & Biology. Jul, 2006 | Pubmed ID: 16873017 Saccharomyces Cerevisiae-based Molecular Tool Kit for Manipulation of Genes from Gram-negative Bacteria Applied and Environmental Microbiology. Jul, 2006 | Pubmed ID: 16820502 Catheter Lock Solutions Influence Staphylococcal Biofilm Formation on Abiotic Surfaces Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Aug, 2006 | Pubmed ID: 16627606 Biofilm Formation by Pseudomonas Fluorescens WCS365: a Role for LapD Microbiology (Reading, England). May, 2006 | Pubmed ID: 16622054 Conservation of the Pho Regulon in Pseudomonas Fluorescens Pf0-1 Applied and Environmental Microbiology. Mar, 2006 | Pubmed ID: 16517638 Pseudomonas Aeruginosa Inhibits Endocytic Recycling of CFTR in Polarized Human Airway Epithelial Cells American Journal of Physiology. Cell Physiology. Mar, 2006 | Pubmed ID: 16236828 Growing and Analyzing Static Biofilms Current Protocols in Microbiology. Jul, 2005 | Pubmed ID: 18770545 Bacterial Biofilms and Ocular Infections The Ocular Surface. Apr, 2005 | Pubmed ID: 17131010 Biofilms Strike Back Nature Biotechnology. Nov, 2005 | Pubmed ID: 16273068 Pseudomonas Aeruginosa Rhamnolipids Disperse Bordetella Bronchiseptica Biofilms FEMS Microbiology Letters. Sep, 2005 | Pubmed ID: 16098688 Heparin Stimulates Staphylococcus Aureus Biofilm Formation Infection and Immunity. Aug, 2005 | Pubmed ID: 16040971 Susceptibility of Biofilms to Bdellovibrio Bacteriovorus Attack Applied and Environmental Microbiology. Jul, 2005 | Pubmed ID: 16000819 A Three-component Regulatory System Regulates Biofilm Maturation and Type III Secretion in Pseudomonas Aeruginosa Journal of Bacteriology. Feb, 2005 | Pubmed ID: 15687209 Evidence for Two Flagellar Stators and Their Role in the Motility of Pseudomonas Aeruginosa Journal of Bacteriology. Jan, 2005 | Pubmed ID: 15629949 Microbiology: Jekyll or Hide? Nature. Dec, 2004 | Pubmed ID: 15592392 Role of CysE in Production of an Extracellular Signaling Molecule in Providencia Stuartii and Escherichia Coli: Loss of CysE Enhances Biofilm Formation in Escherichia Coli Journal of Bacteriology. Nov, 2004 | Pubmed ID: 15516574 SadB is Required for the Transition from Reversible to Irreversible Attachment During Biofilm Formation by Pseudomonas Aeruginosa PA14 Journal of Bacteriology. Jul, 2004 | Pubmed ID: 15231779 Isolation and Characterization of a Generalized Transducing Phage for Pseudomonas Aeruginosa Strains PAO1 and PA14 Journal of Bacteriology. May, 2004 | Pubmed ID: 15126493 A Genetic Basis for Pseudomonas Aeruginosa Biofilm Antibiotic Resistance Nature. Nov, 2003 | Pubmed ID: 14628055 Transition from Reversible to Irreversible Attachment During Biofilm Formation by Pseudomonas Fluorescens WCS365 Requires an ABC Transporter and a Large Secreted Protein Molecular Microbiology. Aug, 2003 | Pubmed ID: 12890017 Alginate is Not a Significant Component of the Extracellular Polysaccharide Matrix of PA14 and PAO1 Pseudomonas Aeruginosa Biofilms Proceedings of the National Academy of Sciences of the United States of America. Jun, 2003 | Pubmed ID: 12810959 To Build a Biofilm Journal of Bacteriology. May, 2003 | Pubmed ID: 12700246 Rhamnolipid Surfactant Production Affects Biofilm Architecture in Pseudomonas Aeruginosa PAO1 Journal of Bacteriology. Feb, 2003 | Pubmed ID: 12533479 Microbiology: a Resistance Switch Nature. Apr, 2002 | Pubmed ID: 11961541 Projeto e Desenvolvimento de um Modelo para Estudar o Efeito do Oxigênio Suplementar no Microbioma da Fibrose Cística Jacob Vieira1, Tara Gallagher2, Hui-Yu Sui1, Sirus Jesudasen3, Katrine Whiteson2, George A. O'Toole4, Kurt Hanselmann5, Peggy S. Lai1 1Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, 2Department of Molecular Biology & Biochemistry, University of California, Irvine, 3Department of Medicine, Massachusetts General Hospital, 4Department of Microbiology & Immunology, Geisel School of Medicine at Dartmouth, 5Swiss i-research and teaching institute JoVE 62888 Medicine Dish microtitulação Assay formação de biofilme George A. O'Toole1 1Microbiology and Immunology, Dartmouth Medical School JoVE 2437 Immunology and Infection
Projeto e Desenvolvimento de um Modelo para Estudar o Efeito do Oxigênio Suplementar no Microbioma da Fibrose Cística Jacob Vieira1, Tara Gallagher2, Hui-Yu Sui1, Sirus Jesudasen3, Katrine Whiteson2, George A. O'Toole4, Kurt Hanselmann5, Peggy S. Lai1 1Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, 2Department of Molecular Biology & Biochemistry, University of California, Irvine, 3Department of Medicine, Massachusetts General Hospital, 4Department of Microbiology & Immunology, Geisel School of Medicine at Dartmouth, 5Swiss i-research and teaching institute JoVE 62888 Medicine
Dish microtitulação Assay formação de biofilme George A. O'Toole1 1Microbiology and Immunology, Dartmouth Medical School JoVE 2437 Immunology and Infection
