George A. O'Toole Department of Microbiology & Immunology Geisel School of Medicine at Dartmouth Biography Publications Institution JoVE Articles George A. O'Toole has not added a biography. If you are George A. O'Toole and would like to personalize this page please email our Author Liaison for assistance. Publications The Gut-Lung Axis in Cystic Fibrosis Journal of Bacteriology. Aug, 2021 | Pubmed ID: 34339302 Biochemical and Structural Characterization of Two Cif-like Epoxide Hydrolases from Current Research in Structural Biology. 2021 | Pubmed ID: 34235487 Mild Cystic Fibrosis Lung Disease Is Associated with Bacterial Community Stability Microbiology Spectrum. Jul, 2021 | Pubmed ID: 34232099 Interaction Between the Type 4 Pili Machinery and a Diguanylate Cyclase Fine-tune C-di-GMP Levels During Early Biofilm Formation Proceedings of the National Academy of Sciences of the United States of America. Jun, 2021 | Pubmed ID: 34168081 One Versus Many: Polymicrobial Communities and the Cystic Fibrosis Airway MBio. 03, 2021 | Pubmed ID: 33727344 Characterization of Ciprofloxacin Resistance Levels: Implications for Ototopical Therapy Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 08, 2021 | Pubmed ID: 33710149 Metabolic Modeling to Interrogate Microbial Disease: A Tale for Experimentalists Frontiers in Molecular Biosciences. 2021 | Pubmed ID: 33681294 Uses C-di-GMP Phosphodiesterases RmcA and MorA To Regulate Biofilm Maintenance MBio. 02, 2021 | Pubmed ID: 33531388 Roadmap on Emerging Concepts in the Physical Biology of Bacterial Biofilms: from Surface Sensing to Community Formation Physical Biology. Jun, 2021 | Pubmed ID: 33462162 Identification of Cell-surface Glycans That Mediate Motility-dependent Binding and Internalization of Pseudomonas Aeruginosa by Phagocytes Molecular Immunology. 03, 2021 | Pubmed ID: 33358569 Aerosolized Drug-loaded Nanoparticles Targeting Migration Inhibitory Factors Inhibit -induced Inflammation and Biofilm Formation Nanomedicine (London, England). 12, 2020 | Pubmed ID: 33241979 Discovering the Molecular Determinants of Phaeobacter Inhibens Susceptibility to Phaeobacter Phage MD18 MSphere. 11, 2020 | Pubmed ID: 33148823 From Input to Output: The Lap/c-di-GMP Biofilm Regulatory Circuit Annual Review of Microbiology. 09, 2020 | Pubmed ID: 32689917 Pseudomonas Aeruginosa PA14 Enhances the Efficacy of Norfloxacin Against Staphylococcus Aureus Newman Biofilms Journal of Bacteriology. 08, 2020 | Pubmed ID: 32661077 MapA, a Second Large RTX Adhesin Conserved Across the Pseudomonads, Contributes to Biofilm Formation by Pseudomonas Fluorescens Journal of Bacteriology. 08, 2020 | Pubmed ID: 32631946 Age and Environmental Exposures Influence the Fecal Bacteriome of Young Children with Cystic Fibrosis Pediatric Pulmonology. 07, 2020 | Pubmed ID: 32275127 Lung Function and Microbiota Diversity in Cystic Fibrosis Microbiome. 04, 2020 | Pubmed ID: 32238195 Social Cooperativity of Bacteria During Reversible Surface Attachment in Young Biofilms: a Quantitative Comparison of Pseudomonas Aeruginosa PA14 and PAO1 MBio. 02, 2020 | Pubmed ID: 32098815 Exogenous Alginate Protects Staphylococcus Aureus from Killing by Pseudomonas Aeruginosa Journal of Bacteriology. Mar, 2020 | Pubmed ID: 31792010 Availability of Zinc Impacts Interactions Between Streptococcus Sanguinis and Pseudomonas Aeruginosa in Coculture Journal of Bacteriology. 01, 2020 | Pubmed ID: 31685535 Gross Transcriptomic Analysis of Pseudomonas Putida for Diagnosing Environmental Shifts Microbial Biotechnology. 01, 2020 | Pubmed ID: 30957409 Interspecies Interactions Induce Exploratory Motility in ELife. 11, 2019 | Pubmed ID: 31713513 Lying in Wait: Modeling the Control of Bacterial Infections Via Antibiotic-Induced Proviruses MSystems. Oct, 2019 | Pubmed ID: 31575664 "It Takes a Village": Mechanisms Underlying Antimicrobial Recalcitrance of Polymicrobial Biofilms Journal of Bacteriology. 12, 2019 | Pubmed ID: 31548277 Glycocluster Tetrahydroxamic Acids Exhibiting Unprecedented Inhibition of Biofilms Journal of Medicinal Chemistry. 09, 2019 | Pubmed ID: 31449405 Special Meeting Issue for the 8th ASM Conference on Biofilms Journal of Bacteriology. 09, 2019 | Pubmed ID: 31439756 Pseudomonas Aeruginosa Increases the Sensitivity of Biofilm-Grown Staphylococcus Aureus to Membrane-Targeting Antiseptics and Antibiotics MBio. 07, 2019 | Pubmed ID: 31363032 Altered Stool Microbiota of Infants with Cystic Fibrosis Shows a Reduction in Genera Associated with Immune Programming from Birth Journal of Bacteriology. 08, 2019 | Pubmed ID: 31209076 Bordetella Bronchiseptica Diguanylate Cyclase BdcA Regulates Motility and Is Important for the Establishment of Respiratory Infection in Mice Journal of Bacteriology. 09, 2019 | Pubmed ID: 31209073 Metabolic Modeling of Cystic Fibrosis Airway Communities Predicts Mechanisms of Pathogen Dominance MSystems. Mar-Apr, 2019 | Pubmed ID: 31020043 The Yin and Yang of Lung Infections in Cystic Fibrosis: a Model for Studying Polymicrobial Interactions Journal of Bacteriology. 06, 2019 | Pubmed ID: 30885933 Pseudomonas Aeruginosa Can Inhibit Growth of Streptococcal Species Via Siderophore Production Journal of Bacteriology. 04, 2019 | Pubmed ID: 30718303 Flagellar Stators Stimulate C-di-GMP Production by Pseudomonas Aeruginosa Journal of Bacteriology. 09, 2019 | Pubmed ID: 30642992 Co-opting the Lap System of Pseudomonas Fluorescens To Reversibly Customize Bacterial Cell Surfaces ACS Synthetic Biology. 11, 2018 | Pubmed ID: 30278125 Ligand-Mediated Biofilm Formation Via Enhanced Physical Interaction Between a Diguanylate Cyclase and Its Receptor MBio. 07, 2018 | Pubmed ID: 29991582 Special Sections for the 6th ASM Conference on Cell-Cell Communication in Bacteria Journal of Bacteriology. 07, 2018 | Pubmed ID: 29941545 Type 1 Does the Two-Step: Type 1 Secretion Substrates with a Functional Periplasmic Intermediate Journal of Bacteriology. 09, 2018 | Pubmed ID: 29866808 Multigenerational Memory and Adaptive Adhesion in Early Bacterial Biofilm Communities Proceedings of the National Academy of Sciences of the United States of America. 04, 2018 | Pubmed ID: 29559526 An N-Terminal Retention Module Anchors the Giant Adhesin LapA of Pseudomonas Fluorescens at the Cell Surface: a Novel Subfamily of Type I Secretion Systems Journal of Bacteriology. 04, 2018 | Pubmed ID: 29437852 A Multimodal Strategy Used by a Large C-di-GMP Network Journal of Bacteriology. 04, 2018 | Pubmed ID: 29311282 Cystic Fibrosis Airway Microbiome: Overturning the Old, Opening the Way for the New Journal of Bacteriology. 02, 2018 | Pubmed ID: 29084859 Special Meeting Sections for the ASM Conference on Mechanisms of Interbacterial Cooperation and Competition Journal of Bacteriology. 11, 2017 | Pubmed ID: 29042432 An Antipersister Strategy for Treatment of Chronic Pseudomonas Aeruginosa Infections Antimicrobial Agents and Chemotherapy. Dec, 2017 | Pubmed ID: 28923873 High-Speed "4D" Computational Microscopy of Bacterial Surface Motility ACS Nano. 09, 2017 | Pubmed ID: 28836761 Alters Staphylococcus Sensitivity to Vancomycin in a Biofilm Model of Cystic Fibrosis Infection MBio. 07, 2017 | Pubmed ID: 28720732 Special Meeting Sections for the 6th ASM Conference on Beneficial Microbes Journal of Bacteriology. 08, 2017 | Pubmed ID: 28698224 A Symphony of Cyclases: Specificity in Diguanylate Cyclase Signaling Annual Review of Microbiology. 09, 2017 | Pubmed ID: 28645224 Classic Spotlights: Selected Highlights from the First 100 Years of the Journal of Bacteriology. 07, 2017 | Pubmed ID: 28611240 Pseudomonas Aeruginosa-Derived Rhamnolipids and Other Detergents Modulate Colony Morphotype and Motility in the Burkholderia Cepacia Complex Journal of Bacteriology. 07, 2017 | Pubmed ID: 28439038 Alginate Overproduction Promotes Coexistence with in a Model of Cystic Fibrosis Respiratory Infection MBio. 03, 2017 | Pubmed ID: 28325763 Bacteria, Rev Your Engines: Stator Dynamics Regulate Flagellar Motility Journal of Bacteriology. 06, 2017 | Pubmed ID: 28320878 Role of Cyclic Di-GMP and Exopolysaccharide in Type IV Pilus Dynamics Journal of Bacteriology. 04, 2017 | Pubmed ID: 28167523 Special Meeting Sections Journal of Bacteriology. 01, 2016 | Pubmed ID: 28588069 Classic Spotlight: How the Gram Stain Works Journal of Bacteriology. 12, 2016 | Pubmed ID: 27815540 Classic Spotlight: Plate Counting You Can Count On Journal of Bacteriology. 12, 2016 | Pubmed ID: 27815539 Classic Spotlight: Bacteroides Thetaiotaomicron, Starch Utilization, and the Birth of the Microbiome Era Journal of Bacteriology. 10, 2016 | Pubmed ID: 27660335 Special Meeting Sections for the 7th ASM Conference on Biofilms Journal of Bacteriology. 10, 2016 | Pubmed ID: 27613861 Requirements for Pseudomonas Aeruginosa Type I-F CRISPR-Cas Adaptation Determined Using a Biofilm Enrichment Assay Journal of Bacteriology. 11, 2016 | Pubmed ID: 27573013 Cyanide Toxicity to Burkholderia Cenocepacia Is Modulated by Polymicrobial Communities and Environmental Factors Frontiers in Microbiology. 2016 | Pubmed ID: 27242743 Classic Spotlight: Cyclic Di-GMP, the Molecule That Makes the Bacterial World Stop Going 'Round Journal of Bacteriology. 06, 2016 | Pubmed ID: 27179064 PilZ Domain Protein FlgZ Mediates Cyclic Di-GMP-Dependent Swarming Motility Control in Pseudomonas Aeruginosa Journal of Bacteriology. 07, 2016 | Pubmed ID: 27114465 The Inhibitory Site of a Diguanylate Cyclase Is a Necessary Element for Interaction and Signaling with an Effector Protein Journal of Bacteriology. 06, 2016 | Pubmed ID: 27002135 Sensational Biofilms: Surface Sensing in Bacteria Current Opinion in Microbiology. Apr, 2016 | Pubmed ID: 26968016 Friendly Fire: Biological Functions and Consequences of Chromosomal Targeting by CRISPR-Cas Systems Journal of Bacteriology. 05, 2016 | Pubmed ID: 26929301 Species-dependent Hydrodynamics of Flagellum-tethered Bacteria in Early Biofilm Development Journal of the Royal Society, Interface. Feb, 2016 | Pubmed ID: 26864892 Classic Spotlight: Quorum Sensing and the Multicellular Life of Unicellular Organisms Journal of Bacteriology. Feb, 2016 | Pubmed ID: 26825965 Classic Spotlight: Before They Were Biofilms Journal of Bacteriology. 01, 2016 | Pubmed ID: 26668270 Tobramycin-Treated Pseudomonas Aeruginosa PA14 Enhances Streptococcus Constellatus 7155 Biofilm Formation in a Cystic Fibrosis Model System Journal of Bacteriology. 01, 2016 | Pubmed ID: 26483523 Cyclic Di-GMP-Regulated Periplasmic Proteolysis of a Pseudomonas Aeruginosa Type Vb Secretion System Substrate Journal of Bacteriology. 01, 2016 | Pubmed ID: 26100041 Cystic Fibrosis Lung Infections: Polymicrobial, Complex, and Hard to Treat PLoS Pathogens. Dec, 2015 | Pubmed ID: 26719892 Iron-dependent Gene Expression in Actinomyces Oris Journal of Oral Microbiology. 2015 | Pubmed ID: 26685151 Contribution of Physical Interactions to Signaling Specificity Between a Diguanylate Cyclase and Its Effector MBio. Dec, 2015 | Pubmed ID: 26670387 Mannitol Does Not Enhance Tobramycin Killing of Pseudomonas Aeruginosa in a Cystic Fibrosis Model System of Biofilm Formation PloS One. 2015 | Pubmed ID: 26506004 C-di-GMP and Its Effects on Biofilm Formation and Dispersion: a Pseudomonas Aeruginosa Review Microbiology Spectrum. Apr, 2015 | Pubmed ID: 26104694 Haemophilus Influenzae Responds to Glucocorticoids Used in Asthma Therapy by Modulation of Biofilm Formation and Antibiotic Resistance EMBO Molecular Medicine. Aug, 2015 | Pubmed ID: 25995336 Clustered Regularly Interspaced Short Palindromic Repeat-Dependent, Biofilm-Specific Death of Pseudomonas Aeruginosa Mediated by Increased Expression of Phage-Related Genes MBio. May, 2015 | Pubmed ID: 25968642 Coculture of Staphylococcus Aureus with Pseudomonas Aeruginosa Drives S. Aureus Towards Fermentative Metabolism and Reduced Viability in a Cystic Fibrosis Model Journal of Bacteriology. Jul, 2015 | Pubmed ID: 25917910 Associations Between Gut Microbial Colonization in Early Life and Respiratory Outcomes in Cystic Fibrosis The Journal of Pediatrics. Jul, 2015 | Pubmed ID: 25818499 A Hierarchical Cascade of Second Messengers Regulates Pseudomonas Aeruginosa Surface Behaviors MBio. Jan, 2015 | Pubmed ID: 25626906 Characterization and Quantification of the Fungal Microbiome in Serial Samples from Individuals with Cystic Fibrosis Microbiome. 2014 | Pubmed ID: 25408892 Surface Attachment Induces Pseudomonas Aeruginosa Virulence Proceedings of the National Academy of Sciences of the United States of America. Nov, 2014 | Pubmed ID: 25385640 Candida Albicans Ethanol Stimulates Pseudomonas Aeruginosa WspR-controlled Biofilm Formation As Part of a Cyclic Relationship Involving Phenazines PLoS Pathogens. Oct, 2014 | Pubmed ID: 25340349 Mechanistic Insight into the Conserved Allosteric Regulation of Periplasmic Proteolysis by the Signaling Molecule Cyclic-di-GMP ELife. Sep, 2014 | Pubmed ID: 25182848 Epoxide-mediated Differential Packaging of Cif and Other Virulence Factors into Outer Membrane Vesicles Journal of Bacteriology. Oct, 2014 | Pubmed ID: 25112474 The Microbiome in Pediatric Cystic Fibrosis Patients: the Role of Shared Environment Suggests a Window of Intervention Microbiome. 2014 | Pubmed ID: 25071935 The Microbiota Regulates Susceptibility to Fas-mediated Acute Hepatic Injury Laboratory Investigation; a Journal of Technical Methods and Pathology. Sep, 2014 | Pubmed ID: 25068658 Structural Features of the Pseudomonas Fluorescens Biofilm Adhesin LapA Required for LapG-dependent Cleavage, Biofilm Formation, and Cell Surface Localization Journal of Bacteriology. Aug, 2014 | Pubmed ID: 24837291 Plate-based Assay for Swarming Motility in Pseudomonas Aeruginosa Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24818898 Plate-based Assay for Swimming Motility in Pseudomonas Aeruginosa Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24818897 Micro-patterned Surfaces Reduce Bacterial Colonization and Biofilm Formation in Vitro: Potential for Enhancing Endotracheal Tube Designs Clinical and Translational Medicine. 2014 | Pubmed ID: 24739529 Deletion Mutant Library for Investigation of Functional Outputs of Cyclic Diguanylate Metabolism in Pseudomonas Aeruginosa PA14 Applied and Environmental Microbiology. Jun, 2014 | Pubmed ID: 24657857 Single-cell and Single-molecule Analysis Deciphers the Localization, Adhesion, and Mechanics of the Biofilm Adhesin LapA ACS Chemical Biology. Feb, 2014 | Pubmed ID: 24556201 Pseudomonas Aeruginosa Flagellar Motility Activates the Phagocyte PI3K/Akt Pathway to Induce Phagocytic Engulfment American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2014 | Pubmed ID: 24487390 Signature Motifs Identify an Acinetobacter Cif Virulence Factor with Epoxide Hydrolase Activity The Journal of Biological Chemistry. Mar, 2014 | Pubmed ID: 24474692 Single-molecule Analysis of Pseudomonas Fluorescens Footprints ACS Nano. Feb, 2014 | Pubmed ID: 24456070 Synthesis of Bioinspired Carbohydrate Amphiphiles That Promote and Inhibit Biofilms Chemical Science (Royal Society of Chemistry : 2010). Feb, 2014 | Pubmed ID: 24376911 Iron Supplementation Does Not Worsen Respiratory Health or Alter the Sputum Microbiome in Cystic Fibrosis Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. May, 2014 | Pubmed ID: 24332997 Unique Microbial Communities Persist in Individual Cystic Fibrosis Patients Throughout a Clinical Exacerbation Microbiome. Nov, 2013 | Pubmed ID: 24451123 Pouring Salt on a Wound: Pseudomonas Aeruginosa Virulence Factors Alter Na+ and Cl- Flux in the Lung Journal of Bacteriology. Sep, 2013 | Pubmed ID: 23836869 Eradication of Pseudomonas Aeruginosa Biofilms on Cultured Airway Cells by a Fosfomycin/tobramycin Antibiotic Combination Pathogens and Disease. Feb, 2013 | Pubmed ID: 23620118 Cyclic-di-GMP Signalling Regulates Motility and Biofilm Formation in Bordetella Bronchiseptica Microbiology (Reading, England). May, 2013 | Pubmed ID: 23475948 Atomic Force and Super-resolution Microscopy Support a Role for LapA As a Cell-surface Biofilm Adhesin of Pseudomonas Fluorescens Research in Microbiology. Nov-Dec, 2012 | Pubmed ID: 23064158 Second Messenger Regulation of Biofilm Formation: Breakthroughs in Understanding C-di-GMP Effector Systems Annual Review of Cell and Developmental Biology. 2012 | Pubmed ID: 23057745 The CRISPR/Cas Adaptive Immune System of Pseudomonas Aeruginosa Mediates Resistance to Naturally Occurring and Engineered Phages Journal of Bacteriology. Nov, 2012 | Pubmed ID: 22885297 Iron Homeostasis During Cystic Fibrosis Pulmonary Exacerbation Clinical and Translational Science. Aug, 2012 | Pubmed ID: 22883617 Epoxide-mediated CifR Repression of Cif Gene Expression Utilizes Two Binding Sites in Pseudomonas Aeruginosa Journal of Bacteriology. Oct, 2012 | Pubmed ID: 22843844 In Vitro Evaluation of Tobramycin and Aztreonam Versus Pseudomonas Aeruginosa Biofilms on Cystic Fibrosis-derived Human Airway Epithelial Cells The Journal of Antimicrobial Chemotherapy. Nov, 2012 | Pubmed ID: 22843834 Does the F508-CFTR Mutation Induce a Proinflammatory Response in Human Airway Epithelial Cells? American Journal of Physiology. Lung Cellular and Molecular Physiology. Sep, 2012 | Pubmed ID: 22821996 LapG, Required for Modulating Biofilm Formation by Pseudomonas Fluorescens Pf0-1, is a Calcium-dependent Protease Journal of Bacteriology. Aug, 2012 | Pubmed ID: 22707708 Structural Characterization of a Conserved, Calcium-dependent Periplasmic Protease from Legionella Pneumophila Journal of Bacteriology. Aug, 2012 | Pubmed ID: 22707706 Diphosphonium Ionische Flüssigkeiten Als Breitspektrum Antimikrobieller Mittel Cornea. Jan, 2012 | Pubmed ID: 22236790 Bakterieller Cis-2-ungesättigter Fettsäuren Gefunden in Der Mukoviszidose-Fluglinie Modulieren Virulenz Und Persistenz Von Pseudomonas Aeruginosa The ISME Journal. Dec, 2011 | Pubmed ID: 22134647 Ausnutzung Der Dendrimere Multivalenz Zur Bekämpfung Der Schwellen- Und Ersteht Jetzt Wieder Auf Infektionskrankheiten Molecular Pharmaceutics. Dec, 2011 | Pubmed ID: 22126461 2-Eine-4-CHINOLON, Ein Vorläufer Der Pseudomonas Quinolone Signalmolekül, Moduliert Schwärmen Motilität in Pseudomonas Aeruginosa Journal of Bacteriology. Dec, 2011 | Pubmed ID: 21965567 Schrittweisen Verlust Der Bakteriellen Flimmerband Torsion Verleiht Progressive Phagozytische Ausweichen PLoS Pathogens. Sep, 2011 | Pubmed ID: 21949654 Systematische Analyse Der Diguanylate Bearbeitet, Die Förderung Von Biofilm-Bildung Durch Pseudomonas Fluorescens Pf0-1 Journal of Bacteriology. Sep, 2011 | Pubmed ID: 21764921 Modulation Von Pseudomonas Aeruginosa Gruppe Oberfläche-assoziierte Verhaltensweisen Von Einzelnen Aminosäuren Durch C-di-GMP Zu Signalisieren Research in Microbiology. Sep, 2011 | Pubmed ID: 21554951 Ein Pseudomonas-Aeruginosa-Toxin, Das Das Proteolytische Ubiquitin-Hostsystem Entführt PLoS Pathogens. Mar, 2011 | Pubmed ID: 21455491 Non-Identität-vermittelter CRISPR-Bakteriophage Interaktion Vermittelt über Die Csy Und Cas3 Proteine Journal of Bacteriology. Jul, 2011 | Pubmed ID: 21398535 Strukturelle Grundlage Für C-di-GMP-vermittelter Inside-Out-Signalisierung Steuernde Periplasmatischen Proteolyse PLoS Biology. 2011 | Pubmed ID: 21304926 Ein C-di-GMP-Effektor-System Steuert Die Zelladhäsion Von Innen Nach Außen Zu Signalisieren Und Oberfläche Protein Decolleté PLoS Biology. 2011 | Pubmed ID: 21304920 Aminoglykoside Widerstand Von Pseudomonas Aeruginosa Biofilme Moduliert Durch Extrazelluläre Polysaccharide International Microbiology : the Official Journal of the Spanish Society for Microbiology. Dec, 2010 | Pubmed ID: 21404215 Spezifische Kontrolle Von Pseudomonas Aeruginosa Oberfläche-assoziierte Verhaltensweisen Von Zwei C-di-GMP Diguanylate Bearbeitet MBio. 2010 | Pubmed ID: 20978535 Staphylococcus Aureus Resistenz Auf Titanbeschichtet Mit Multivalenter Pegylierte-Peptide Biomaterials. Dec, 2010 | Pubmed ID: 20863561 Pseudomonas Aeruginosa Ausweichen Der Phagozytose Wird Vermittelt Durch Den Verlust Der Beweglichkeit Der Spermien Schwimmen Und Ist Unabhängig Von Flagellen Ausdruck Infection and Immunity. Jul, 2010 | Pubmed ID: 20457788 Antikörper Und Immun Effektoren: Gestaltung Gramnegative Bakterielle Phänotypen Trends in Microbiology. Jun, 2010 | Pubmed ID: 20359893 Cyclic-di-GMP-vermittelter Unterdrückung Der Motilität Von Pseudomonas Aeruginosa Schwärmen: Das PilY1-gen Und Deren Auswirkungen Auf Die Oberfläche-assoziierte Verhaltensweisen Journal of Bacteriology. Jun, 2010 | Pubmed ID: 20233936 Di-Adenosin-Tetraphosphate (Ap4A)-Stoffwechsel Wirkt Biofilm-Bildung Durch Pseudomonas Fluorescens über Modulation Der C-di-GMP-abhängigen Bahnen Journal of Bacteriology. Jun, 2010 | Pubmed ID: 20154123 Kristallstruktur Von Der Cystic Fibrosis Transmembrane Conductance Regler Hemmender Faktor Cif Zeigt Neuartige Aktiven-Site Features Von Virulenzfaktoren Ein Epoxid-Hydrolase Journal of Bacteriology. Apr, 2010 | Pubmed ID: 20118260 Zucker-Fettsäureester Hemmen Biofilm-Bildung Durch Lebensmittel übertragbaren Pathogenen Bakterien International Journal of Food Microbiology. Mar, 2010 | Pubmed ID: 20089325 Der Pseudomonas-Aeruginosa-Magnesium-Transporter MgtE Hemmt Die Transkription Des Typs III-Sekretionssystem Infection and Immunity. Mar, 2010 | Pubmed ID: 20028803 Biofilm Flagellen-vermittelten Abwehrmechanismen Von Pseudomonas Aeruginosa Gegen Host-abgeleitete Lactoferrin Infection and Immunity. Oct, 2009 | Pubmed ID: 19651866 Montage Von Pegylierte-Peptid-Beschichtungen Für Infektion-resistente Titan Metall Gerichtet Journal of the American Chemical Society. Aug, 2009 | Pubmed ID: 19621876 Neue Hefe Recombineering Werkzeuge Für Bakterien Plasmid. Sep, 2009 | Pubmed ID: 19477196 Fernverkehr Lieferung Bakterielle Virulenzfaktoren Von Pseudomonas Aeruginosa Außenmembran Bläschen PLoS Pathogens. Apr, 2009 | Pubmed ID: 19360133 LapD Ist Ein BIZ (3', 5')-zyklische Dimeren GMP-verbindliches Protein, Das Die Oberfläche Anlage Von Pseudomonas Fluorescens Pf0-1 Reguliert Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009 | Pubmed ID: 19218451 Tobramycin Und FDA-zugelassenen Eisen Chelatoren Beseitigen Pseudomonas Aeruginosa Biofilmen Auf Mukoviszidose-Zellen American Journal of Respiratory Cell and Molecular Biology. Sep, 2009 | Pubmed ID: 19168700 Die Entwicklungsbiologie Modell Der Mikrobiellen Biofilmen: Zehn Jahre Ein Paradigma Für Die Rezension Trends in Microbiology. Feb, 2009 | Pubmed ID: 19162483 Interaktion Zwischen Bakteriophage DMS3 Und CRISPR Gastgeberregion Verhindert Gruppe Verhalten Von Pseudomonas Aeruginosa Journal of Bacteriology. Jan, 2009 | Pubmed ID: 18952788 Chemotoxicity Von Doxorubicin Und Oberfläche Ausdruck P-Glykoprotein (MDR1) Wird Durch Die Pseudomonas-Aeruginosa-Toxin Cif Geregelt American Journal of Physiology. Cell Physiology. Sep, 2008 | Pubmed ID: 18650266 CIF Ist Die TetR Familie Hemmer CifR Negativ Geregelt Infection and Immunity. Jul, 2008 | Pubmed ID: 18458065 Die DeltaF508-CFTR-Mutation Führt Erhöhte Biofilm-Bildung Von Pseudomonas Aeruginosa Durch Die Zunehmende Verfügbarkeit Von Eisen American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2008 | Pubmed ID: 18359885 Genetischer Beweis Für Eine Alternative Citrat-abhängige Biofilm Bildung Biosyntheseweges in Staphylococcus Aureus, Die Fibronektin-bindende Proteine Und Das GraRS Zwei-Komponenten-Regulierungssystem Abhängig Ist Infection and Immunity. Jun, 2008 | Pubmed ID: 18347039 Pseudomonas Aeruginosa Biofilm-Bildung in Der Mukoviszidose-Fluglinie Pulmonary Pharmacology & Therapeutics. Aug, 2008 | Pubmed ID: 18234534 In-vitro-Analyse Von Tobramycin Behandelt Pseudomonas Aeruginosa Biofilmen Auf Mukoviszidose Abgeleitete Airway Epithelzellen Infection and Immunity. Apr, 2008 | Pubmed ID: 18212077 In-vivo-Wachstum Von Pseudomonas Aeruginosa Belastungen PAO1 Und PA14 Und Der Hypervirulent Stamm LESB58 in Einem Rattenmodell Der Chronischen Lungenentzündung Journal of Bacteriology. Apr, 2008 | Pubmed ID: 18083816 Die Geißel Von Pseudomonas Aeruginosa Ist Erforderlich Für Widerstand Auf Abholung Durch Surfactant Protein A PloS One. 2007 | Pubmed ID: 17593964 SadC Einflüsse Gegenseitig Biofilm Formation Und Schwärmen Motilität über Modulation Von Exopolysaccharide Produktion Und Flimmerband Funktion Journal of Bacteriology. Nov, 2007 | Pubmed ID: 17586642 BifA, Eine Zyklische-Di-GMP Phosphodiesterase Regelt Umgekehrt Biofilm Formation Und Schwärmen Motilität Von Pseudomonas Aeruginosa PA14 Journal of Bacteriology. Nov, 2007 | Pubmed ID: 17586641 Rollen Für Flimmerband Statoren in Biofilm-Formation Von Pseudomonas Aeruginosa Research in Microbiology. Jun, 2007 | Pubmed ID: 17533122 Das Pseudomonas Aeruginosa Abgesondert Protein PA2934 Verringert Die Apikale Membran Ausdruck Der Cystic Fibrosis Transmembrane Conductance Regulator Infection and Immunity. Aug, 2007 | Pubmed ID: 17502391 Inverse Regelung Der Biofilm Formation Und Schwärmen Motilität Von Pseudomonas Aeruginosa PA14 Journal of Bacteriology. May, 2007 | Pubmed ID: 17337585 Phosphat-abhängigen Modulation Der C-di-GMP Ebenen Regelt Pseudomonas Fluorescens Pf0-1-Biofilm-Bildung Durch Die Kontrolle Der Sekretion Von Adhesin LapA Molecular Microbiology. Feb, 2007 | Pubmed ID: 17302799 Anfälligkeit Von Pathogene Biofilme Für Micavibrio Aeruginosavorus Applied and Environmental Microbiology. Jan, 2007 | Pubmed ID: 17098913 Peptid-PEG Amphiphiles Als Cytophobic Beschichtungen Für Bakterielle Und Säugetier-Zellen Chemistry & Biology. Jul, 2006 | Pubmed ID: 16873017 Saccharomyces Cerevisiae-basiertes Diagnostic Toolkit Für Die Manipulation Von Genen Von Gram-negativen Bakterien Applied and Environmental Microbiology. Jul, 2006 | Pubmed ID: 16820502 Katheter Sperre Lösungen Beeinflussen Staphylokokken Biofilm-Bildung Auf Abiotischen Oberflächen Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Aug, 2006 | Pubmed ID: 16627606 Biofilm-Bildung Durch Pseudomonas Fluorescens WCS365: Eine Rolle Für LapD Microbiology (Reading, England). May, 2006 | Pubmed ID: 16622054 Erhaltung Der Pho Regulon in Pseudomonas Fluorescens Pf0-1 Applied and Environmental Microbiology. Mar, 2006 | Pubmed ID: 16517638 Pseudomonas Aeruginosa Hemmt Endocytic Recycling Von CFTR Polarisierten Menschlichen Atemwege Epithelzellen American Journal of Physiology. Cell Physiology. Mar, 2006 | Pubmed ID: 16236828 Wachsen Und Statische Biofilme Zu Analysieren Current Protocols in Microbiology. Jul, 2005 | Pubmed ID: 18770545 Bakterielle Biofilme Und Okuläre Infektionen The Ocular Surface. Apr, 2005 | Pubmed ID: 17131010 Biofilme Schlagen Zurück Nature Biotechnology. Nov, 2005 | Pubmed ID: 16273068 Pseudomonas Aeruginosa Rhamnolipide Zerstreuen Bordetella Bronchiseptica Biofilmen FEMS Microbiology Letters. Sep, 2005 | Pubmed ID: 16098688 Heparin Stimuliert Staphylococcus Aureus Biofilmbildung Infection and Immunity. Aug, 2005 | Pubmed ID: 16040971 Die Anfälligkeit Von Biofilmen Zu Bdellovibrio Bacteriovorus Angriff Applied and Environmental Microbiology. Jul, 2005 | Pubmed ID: 16000819 Ein Drei-Komponenten-Regelungssystem Regelt Biofilm Reifung Und Typ III Sekretionssystem in Pseudomonas Aeruginosa Journal of Bacteriology. Feb, 2005 | Pubmed ID: 15687209 Der Nachweis Für Zwei Flagellen Statoren Und Ihre Rolle Bei Der Motilität Von Pseudomonas Aeruginosa Journal of Bacteriology. Jan, 2005 | Pubmed ID: 15629949 Mikrobiologie: Jekyll Oder Ausblenden? Nature. Dec, 2004 | Pubmed ID: 15592392 Die Rolle Der CysE Bei Der Herstellung Eines Extrazellulären Signalmolekül in Providencia Stuartii Und Escherichia Coli: Verlust Von CysE Erhöht Biofilmbildung in Escherichia Coli Journal of Bacteriology. Nov, 2004 | Pubmed ID: 15516574 SADB Wird Für Den Übergang Von Reversibel, Um Die Befestigung Während Der Bildung Von Biofilmen Durch Pseudomonas Aeruginosa PA14 Irreversiblen Erforderlich Journal of Bacteriology. Jul, 2004 | Pubmed ID: 15231779 Isolierung Und Charakterisierung Eines Verallgemeinerten Transduzierenden Phagen Für Pseudomonas Aeruginosa-Stämmen PAO1 Und PA14 Journal of Bacteriology. May, 2004 | Pubmed ID: 15126493 Eine Genetische Basis Für Pseudomonas Aeruginosa Biofilm Antibiotikaresistenz Nature. Nov, 2003 | Pubmed ID: 14628055 Der Übergang Von Reversibel, Um Die Befestigung Während Der Biofilmbildung Von Pseudomonas Fluorescens WCS365 Irreversiblen Erfordert Eine ABC-Transporter Und Einen Großen Sekretierten Proteins Molecular Microbiology. Aug, 2003 | Pubmed ID: 12890017 Alginat Ist Nicht Ein Wesentlicher Bestandteil Der Extrazellulären Matrix Von Polysaccharid-PA14 Und PAO1 Pseudomonas Aeruginosa Biofilmen Proceedings of the National Academy of Sciences of the United States of America. Jun, 2003 | Pubmed ID: 12810959 Um Einen Biofilm Aufzubauen Journal of Bacteriology. May, 2003 | Pubmed ID: 12700246 Rhamnolipid Surfactant-Produktion Beeinflusst Biofilm Architektur in Pseudomonas Aeruginosa PAO1 Journal of Bacteriology. Feb, 2003 | Pubmed ID: 12533479 Mikrobiologie: Ein Widerstand Schalter Nature. Apr, 2002 | Pubmed ID: 11961541 Design und Entwicklung eines Modells zur Untersuchung der Wirkung von zusätzlichem Sauerstoff auf das Mukoviszidose-Atemwegsmikrobiom Jacob Vieira1, Tara Gallagher2, Hui-Yu Sui1, Sirus Jesudasen3, Katrine Whiteson2, George A. O'Toole4, Kurt Hanselmann5, Peggy S. Lai1 1Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, 2Department of Molecular Biology & Biochemistry, University of California, Irvine, 3Department of Medicine, Massachusetts General Hospital, 4Department of Microbiology & Immunology, Geisel School of Medicine at Dartmouth, 5Swiss i-research and teaching institute JoVE 62888 Medicine Mikrotiterschale Biofilmbildung Assay George A. O'Toole1 1Microbiology and Immunology, Dartmouth Medical School JoVE 2437 Immunology and Infection
Design und Entwicklung eines Modells zur Untersuchung der Wirkung von zusätzlichem Sauerstoff auf das Mukoviszidose-Atemwegsmikrobiom Jacob Vieira1, Tara Gallagher2, Hui-Yu Sui1, Sirus Jesudasen3, Katrine Whiteson2, George A. O'Toole4, Kurt Hanselmann5, Peggy S. Lai1 1Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, 2Department of Molecular Biology & Biochemistry, University of California, Irvine, 3Department of Medicine, Massachusetts General Hospital, 4Department of Microbiology & Immunology, Geisel School of Medicine at Dartmouth, 5Swiss i-research and teaching institute JoVE 62888 Medicine
Mikrotiterschale Biofilmbildung Assay George A. O'Toole1 1Microbiology and Immunology, Dartmouth Medical School JoVE 2437 Immunology and Infection