George A. O'Toole Department of Microbiology & Immunology Geisel School of Medicine at Dartmouth Biography Publications Institution JoVE Articles George A. O'Toole has not added a biography. If you are George A. O'Toole and would like to personalize this page please email our Author Liaison for assistance. Publications The Gut-Lung Axis in Cystic Fibrosis Journal of Bacteriology. Aug, 2021 | Pubmed ID: 34339302 Biochemical and Structural Characterization of Two Cif-like Epoxide Hydrolases from Current Research in Structural Biology. 2021 | Pubmed ID: 34235487 Mild Cystic Fibrosis Lung Disease Is Associated with Bacterial Community Stability Microbiology Spectrum. Jul, 2021 | Pubmed ID: 34232099 Interaction Between the Type 4 Pili Machinery and a Diguanylate Cyclase Fine-tune C-di-GMP Levels During Early Biofilm Formation Proceedings of the National Academy of Sciences of the United States of America. Jun, 2021 | Pubmed ID: 34168081 One Versus Many: Polymicrobial Communities and the Cystic Fibrosis Airway MBio. 03, 2021 | Pubmed ID: 33727344 Characterization of Ciprofloxacin Resistance Levels: Implications for Ototopical Therapy Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 08, 2021 | Pubmed ID: 33710149 Metabolic Modeling to Interrogate Microbial Disease: A Tale for Experimentalists Frontiers in Molecular Biosciences. 2021 | Pubmed ID: 33681294 Uses C-di-GMP Phosphodiesterases RmcA and MorA To Regulate Biofilm Maintenance MBio. 02, 2021 | Pubmed ID: 33531388 Roadmap on Emerging Concepts in the Physical Biology of Bacterial Biofilms: from Surface Sensing to Community Formation Physical Biology. Jun, 2021 | Pubmed ID: 33462162 Identification of Cell-surface Glycans That Mediate Motility-dependent Binding and Internalization of Pseudomonas Aeruginosa by Phagocytes Molecular Immunology. 03, 2021 | Pubmed ID: 33358569 Aerosolized Drug-loaded Nanoparticles Targeting Migration Inhibitory Factors Inhibit -induced Inflammation and Biofilm Formation Nanomedicine (London, England). 12, 2020 | Pubmed ID: 33241979 Discovering the Molecular Determinants of Phaeobacter Inhibens Susceptibility to Phaeobacter Phage MD18 MSphere. 11, 2020 | Pubmed ID: 33148823 From Input to Output: The Lap/c-di-GMP Biofilm Regulatory Circuit Annual Review of Microbiology. 09, 2020 | Pubmed ID: 32689917 Pseudomonas Aeruginosa PA14 Enhances the Efficacy of Norfloxacin Against Staphylococcus Aureus Newman Biofilms Journal of Bacteriology. 08, 2020 | Pubmed ID: 32661077 MapA, a Second Large RTX Adhesin Conserved Across the Pseudomonads, Contributes to Biofilm Formation by Pseudomonas Fluorescens Journal of Bacteriology. 08, 2020 | Pubmed ID: 32631946 Age and Environmental Exposures Influence the Fecal Bacteriome of Young Children with Cystic Fibrosis Pediatric Pulmonology. 07, 2020 | Pubmed ID: 32275127 Lung Function and Microbiota Diversity in Cystic Fibrosis Microbiome. 04, 2020 | Pubmed ID: 32238195 Social Cooperativity of Bacteria During Reversible Surface Attachment in Young Biofilms: a Quantitative Comparison of Pseudomonas Aeruginosa PA14 and PAO1 MBio. 02, 2020 | Pubmed ID: 32098815 Exogenous Alginate Protects Staphylococcus Aureus from Killing by Pseudomonas Aeruginosa Journal of Bacteriology. Mar, 2020 | Pubmed ID: 31792010 Availability of Zinc Impacts Interactions Between Streptococcus Sanguinis and Pseudomonas Aeruginosa in Coculture Journal of Bacteriology. 01, 2020 | Pubmed ID: 31685535 Gross Transcriptomic Analysis of Pseudomonas Putida for Diagnosing Environmental Shifts Microbial Biotechnology. 01, 2020 | Pubmed ID: 30957409 Interspecies Interactions Induce Exploratory Motility in ELife. 11, 2019 | Pubmed ID: 31713513 Lying in Wait: Modeling the Control of Bacterial Infections Via Antibiotic-Induced Proviruses MSystems. Oct, 2019 | Pubmed ID: 31575664 "It Takes a Village": Mechanisms Underlying Antimicrobial Recalcitrance of Polymicrobial Biofilms Journal of Bacteriology. 12, 2019 | Pubmed ID: 31548277 Glycocluster Tetrahydroxamic Acids Exhibiting Unprecedented Inhibition of Biofilms Journal of Medicinal Chemistry. 09, 2019 | Pubmed ID: 31449405 Special Meeting Issue for the 8th ASM Conference on Biofilms Journal of Bacteriology. 09, 2019 | Pubmed ID: 31439756 Pseudomonas Aeruginosa Increases the Sensitivity of Biofilm-Grown Staphylococcus Aureus to Membrane-Targeting Antiseptics and Antibiotics MBio. 07, 2019 | Pubmed ID: 31363032 Altered Stool Microbiota of Infants with Cystic Fibrosis Shows a Reduction in Genera Associated with Immune Programming from Birth Journal of Bacteriology. 08, 2019 | Pubmed ID: 31209076 Bordetella Bronchiseptica Diguanylate Cyclase BdcA Regulates Motility and Is Important for the Establishment of Respiratory Infection in Mice Journal of Bacteriology. 09, 2019 | Pubmed ID: 31209073 Metabolic Modeling of Cystic Fibrosis Airway Communities Predicts Mechanisms of Pathogen Dominance MSystems. Mar-Apr, 2019 | Pubmed ID: 31020043 The Yin and Yang of Lung Infections in Cystic Fibrosis: a Model for Studying Polymicrobial Interactions Journal of Bacteriology. 06, 2019 | Pubmed ID: 30885933 Pseudomonas Aeruginosa Can Inhibit Growth of Streptococcal Species Via Siderophore Production Journal of Bacteriology. 04, 2019 | Pubmed ID: 30718303 Flagellar Stators Stimulate C-di-GMP Production by Pseudomonas Aeruginosa Journal of Bacteriology. 09, 2019 | Pubmed ID: 30642992 Co-opting the Lap System of Pseudomonas Fluorescens To Reversibly Customize Bacterial Cell Surfaces ACS Synthetic Biology. 11, 2018 | Pubmed ID: 30278125 Ligand-Mediated Biofilm Formation Via Enhanced Physical Interaction Between a Diguanylate Cyclase and Its Receptor MBio. 07, 2018 | Pubmed ID: 29991582 Special Sections for the 6th ASM Conference on Cell-Cell Communication in Bacteria Journal of Bacteriology. 07, 2018 | Pubmed ID: 29941545 Type 1 Does the Two-Step: Type 1 Secretion Substrates with a Functional Periplasmic Intermediate Journal of Bacteriology. 09, 2018 | Pubmed ID: 29866808 Multigenerational Memory and Adaptive Adhesion in Early Bacterial Biofilm Communities Proceedings of the National Academy of Sciences of the United States of America. 04, 2018 | Pubmed ID: 29559526 An N-Terminal Retention Module Anchors the Giant Adhesin LapA of Pseudomonas Fluorescens at the Cell Surface: a Novel Subfamily of Type I Secretion Systems Journal of Bacteriology. 04, 2018 | Pubmed ID: 29437852 A Multimodal Strategy Used by a Large C-di-GMP Network Journal of Bacteriology. 04, 2018 | Pubmed ID: 29311282 Cystic Fibrosis Airway Microbiome: Overturning the Old, Opening the Way for the New Journal of Bacteriology. 02, 2018 | Pubmed ID: 29084859 Special Meeting Sections for the ASM Conference on Mechanisms of Interbacterial Cooperation and Competition Journal of Bacteriology. 11, 2017 | Pubmed ID: 29042432 An Antipersister Strategy for Treatment of Chronic Pseudomonas Aeruginosa Infections Antimicrobial Agents and Chemotherapy. Dec, 2017 | Pubmed ID: 28923873 High-Speed "4D" Computational Microscopy of Bacterial Surface Motility ACS Nano. 09, 2017 | Pubmed ID: 28836761 Alters Staphylococcus Sensitivity to Vancomycin in a Biofilm Model of Cystic Fibrosis Infection MBio. 07, 2017 | Pubmed ID: 28720732 Special Meeting Sections for the 6th ASM Conference on Beneficial Microbes Journal of Bacteriology. 08, 2017 | Pubmed ID: 28698224 A Symphony of Cyclases: Specificity in Diguanylate Cyclase Signaling Annual Review of Microbiology. 09, 2017 | Pubmed ID: 28645224 Classic Spotlights: Selected Highlights from the First 100 Years of the Journal of Bacteriology. 07, 2017 | Pubmed ID: 28611240 Pseudomonas Aeruginosa-Derived Rhamnolipids and Other Detergents Modulate Colony Morphotype and Motility in the Burkholderia Cepacia Complex Journal of Bacteriology. 07, 2017 | Pubmed ID: 28439038 Alginate Overproduction Promotes Coexistence with in a Model of Cystic Fibrosis Respiratory Infection MBio. 03, 2017 | Pubmed ID: 28325763 Bacteria, Rev Your Engines: Stator Dynamics Regulate Flagellar Motility Journal of Bacteriology. 06, 2017 | Pubmed ID: 28320878 Role of Cyclic Di-GMP and Exopolysaccharide in Type IV Pilus Dynamics Journal of Bacteriology. 04, 2017 | Pubmed ID: 28167523 Special Meeting Sections Journal of Bacteriology. 01, 2016 | Pubmed ID: 28588069 Classic Spotlight: How the Gram Stain Works Journal of Bacteriology. 12, 2016 | Pubmed ID: 27815540 Classic Spotlight: Plate Counting You Can Count On Journal of Bacteriology. 12, 2016 | Pubmed ID: 27815539 Classic Spotlight: Bacteroides Thetaiotaomicron, Starch Utilization, and the Birth of the Microbiome Era Journal of Bacteriology. 10, 2016 | Pubmed ID: 27660335 Special Meeting Sections for the 7th ASM Conference on Biofilms Journal of Bacteriology. 10, 2016 | Pubmed ID: 27613861 Requirements for Pseudomonas Aeruginosa Type I-F CRISPR-Cas Adaptation Determined Using a Biofilm Enrichment Assay Journal of Bacteriology. 11, 2016 | Pubmed ID: 27573013 Cyanide Toxicity to Burkholderia Cenocepacia Is Modulated by Polymicrobial Communities and Environmental Factors Frontiers in Microbiology. 2016 | Pubmed ID: 27242743 Classic Spotlight: Cyclic Di-GMP, the Molecule That Makes the Bacterial World Stop Going 'Round Journal of Bacteriology. 06, 2016 | Pubmed ID: 27179064 PilZ Domain Protein FlgZ Mediates Cyclic Di-GMP-Dependent Swarming Motility Control in Pseudomonas Aeruginosa Journal of Bacteriology. 07, 2016 | Pubmed ID: 27114465 The Inhibitory Site of a Diguanylate Cyclase Is a Necessary Element for Interaction and Signaling with an Effector Protein Journal of Bacteriology. 06, 2016 | Pubmed ID: 27002135 Sensational Biofilms: Surface Sensing in Bacteria Current Opinion in Microbiology. Apr, 2016 | Pubmed ID: 26968016 Friendly Fire: Biological Functions and Consequences of Chromosomal Targeting by CRISPR-Cas Systems Journal of Bacteriology. 05, 2016 | Pubmed ID: 26929301 Species-dependent Hydrodynamics of Flagellum-tethered Bacteria in Early Biofilm Development Journal of the Royal Society, Interface. Feb, 2016 | Pubmed ID: 26864892 Classic Spotlight: Quorum Sensing and the Multicellular Life of Unicellular Organisms Journal of Bacteriology. Feb, 2016 | Pubmed ID: 26825965 Classic Spotlight: Before They Were Biofilms Journal of Bacteriology. 01, 2016 | Pubmed ID: 26668270 Tobramycin-Treated Pseudomonas Aeruginosa PA14 Enhances Streptococcus Constellatus 7155 Biofilm Formation in a Cystic Fibrosis Model System Journal of Bacteriology. 01, 2016 | Pubmed ID: 26483523 Cyclic Di-GMP-Regulated Periplasmic Proteolysis of a Pseudomonas Aeruginosa Type Vb Secretion System Substrate Journal of Bacteriology. 01, 2016 | Pubmed ID: 26100041 Cystic Fibrosis Lung Infections: Polymicrobial, Complex, and Hard to Treat PLoS Pathogens. Dec, 2015 | Pubmed ID: 26719892 Iron-dependent Gene Expression in Actinomyces Oris Journal of Oral Microbiology. 2015 | Pubmed ID: 26685151 Contribution of Physical Interactions to Signaling Specificity Between a Diguanylate Cyclase and Its Effector MBio. Dec, 2015 | Pubmed ID: 26670387 Mannitol Does Not Enhance Tobramycin Killing of Pseudomonas Aeruginosa in a Cystic Fibrosis Model System of Biofilm Formation PloS One. 2015 | Pubmed ID: 26506004 C-di-GMP and Its Effects on Biofilm Formation and Dispersion: a Pseudomonas Aeruginosa Review Microbiology Spectrum. Apr, 2015 | Pubmed ID: 26104694 Haemophilus Influenzae Responds to Glucocorticoids Used in Asthma Therapy by Modulation of Biofilm Formation and Antibiotic Resistance EMBO Molecular Medicine. Aug, 2015 | Pubmed ID: 25995336 Clustered Regularly Interspaced Short Palindromic Repeat-Dependent, Biofilm-Specific Death of Pseudomonas Aeruginosa Mediated by Increased Expression of Phage-Related Genes MBio. May, 2015 | Pubmed ID: 25968642 Coculture of Staphylococcus Aureus with Pseudomonas Aeruginosa Drives S. Aureus Towards Fermentative Metabolism and Reduced Viability in a Cystic Fibrosis Model Journal of Bacteriology. Jul, 2015 | Pubmed ID: 25917910 Associations Between Gut Microbial Colonization in Early Life and Respiratory Outcomes in Cystic Fibrosis The Journal of Pediatrics. Jul, 2015 | Pubmed ID: 25818499 A Hierarchical Cascade of Second Messengers Regulates Pseudomonas Aeruginosa Surface Behaviors MBio. Jan, 2015 | Pubmed ID: 25626906 Characterization and Quantification of the Fungal Microbiome in Serial Samples from Individuals with Cystic Fibrosis Microbiome. 2014 | Pubmed ID: 25408892 Surface Attachment Induces Pseudomonas Aeruginosa Virulence Proceedings of the National Academy of Sciences of the United States of America. Nov, 2014 | Pubmed ID: 25385640 Candida Albicans Ethanol Stimulates Pseudomonas Aeruginosa WspR-controlled Biofilm Formation As Part of a Cyclic Relationship Involving Phenazines PLoS Pathogens. Oct, 2014 | Pubmed ID: 25340349 Mechanistic Insight into the Conserved Allosteric Regulation of Periplasmic Proteolysis by the Signaling Molecule Cyclic-di-GMP ELife. Sep, 2014 | Pubmed ID: 25182848 Epoxide-mediated Differential Packaging of Cif and Other Virulence Factors into Outer Membrane Vesicles Journal of Bacteriology. Oct, 2014 | Pubmed ID: 25112474 The Microbiome in Pediatric Cystic Fibrosis Patients: the Role of Shared Environment Suggests a Window of Intervention Microbiome. 2014 | Pubmed ID: 25071935 The Microbiota Regulates Susceptibility to Fas-mediated Acute Hepatic Injury Laboratory Investigation; a Journal of Technical Methods and Pathology. Sep, 2014 | Pubmed ID: 25068658 Structural Features of the Pseudomonas Fluorescens Biofilm Adhesin LapA Required for LapG-dependent Cleavage, Biofilm Formation, and Cell Surface Localization Journal of Bacteriology. Aug, 2014 | Pubmed ID: 24837291 Plate-based Assay for Swarming Motility in Pseudomonas Aeruginosa Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24818898 Plate-based Assay for Swimming Motility in Pseudomonas Aeruginosa Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24818897 Micro-patterned Surfaces Reduce Bacterial Colonization and Biofilm Formation in Vitro: Potential for Enhancing Endotracheal Tube Designs Clinical and Translational Medicine. 2014 | Pubmed ID: 24739529 Deletion Mutant Library for Investigation of Functional Outputs of Cyclic Diguanylate Metabolism in Pseudomonas Aeruginosa PA14 Applied and Environmental Microbiology. Jun, 2014 | Pubmed ID: 24657857 Single-cell and Single-molecule Analysis Deciphers the Localization, Adhesion, and Mechanics of the Biofilm Adhesin LapA ACS Chemical Biology. Feb, 2014 | Pubmed ID: 24556201 Pseudomonas Aeruginosa Flagellar Motility Activates the Phagocyte PI3K/Akt Pathway to Induce Phagocytic Engulfment American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2014 | Pubmed ID: 24487390 Signature Motifs Identify an Acinetobacter Cif Virulence Factor with Epoxide Hydrolase Activity The Journal of Biological Chemistry. Mar, 2014 | Pubmed ID: 24474692 Single-molecule Analysis of Pseudomonas Fluorescens Footprints ACS Nano. Feb, 2014 | Pubmed ID: 24456070 Synthesis of Bioinspired Carbohydrate Amphiphiles That Promote and Inhibit Biofilms Chemical Science (Royal Society of Chemistry : 2010). Feb, 2014 | Pubmed ID: 24376911 Iron Supplementation Does Not Worsen Respiratory Health or Alter the Sputum Microbiome in Cystic Fibrosis Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. May, 2014 | Pubmed ID: 24332997 Unique Microbial Communities Persist in Individual Cystic Fibrosis Patients Throughout a Clinical Exacerbation Microbiome. Nov, 2013 | Pubmed ID: 24451123 Pouring Salt on a Wound: Pseudomonas Aeruginosa Virulence Factors Alter Na+ and Cl- Flux in the Lung Journal of Bacteriology. Sep, 2013 | Pubmed ID: 23836869 Eradication of Pseudomonas Aeruginosa Biofilms on Cultured Airway Cells by a Fosfomycin/tobramycin Antibiotic Combination Pathogens and Disease. Feb, 2013 | Pubmed ID: 23620118 Cyclic-di-GMP Signalling Regulates Motility and Biofilm Formation in Bordetella Bronchiseptica Microbiology (Reading, England). May, 2013 | Pubmed ID: 23475948 Atomic Force and Super-resolution Microscopy Support a Role for LapA As a Cell-surface Biofilm Adhesin of Pseudomonas Fluorescens Research in Microbiology. Nov-Dec, 2012 | Pubmed ID: 23064158 Second Messenger Regulation of Biofilm Formation: Breakthroughs in Understanding C-di-GMP Effector Systems Annual Review of Cell and Developmental Biology. 2012 | Pubmed ID: 23057745 The CRISPR/Cas Adaptive Immune System of Pseudomonas Aeruginosa Mediates Resistance to Naturally Occurring and Engineered Phages Journal of Bacteriology. Nov, 2012 | Pubmed ID: 22885297 Iron Homeostasis During Cystic Fibrosis Pulmonary Exacerbation Clinical and Translational Science. Aug, 2012 | Pubmed ID: 22883617 Epoxide-mediated CifR Repression of Cif Gene Expression Utilizes Two Binding Sites in Pseudomonas Aeruginosa Journal of Bacteriology. Oct, 2012 | Pubmed ID: 22843844 In Vitro Evaluation of Tobramycin and Aztreonam Versus Pseudomonas Aeruginosa Biofilms on Cystic Fibrosis-derived Human Airway Epithelial Cells The Journal of Antimicrobial Chemotherapy. Nov, 2012 | Pubmed ID: 22843834 Does the F508-CFTR Mutation Induce a Proinflammatory Response in Human Airway Epithelial Cells? American Journal of Physiology. Lung Cellular and Molecular Physiology. Sep, 2012 | Pubmed ID: 22821996 LapG, Required for Modulating Biofilm Formation by Pseudomonas Fluorescens Pf0-1, is a Calcium-dependent Protease Journal of Bacteriology. Aug, 2012 | Pubmed ID: 22707708 Structural Characterization of a Conserved, Calcium-dependent Periplasmic Protease from Legionella Pneumophila Journal of Bacteriology. Aug, 2012 | Pubmed ID: 22707706 Diphosphonium Ionic Liquids As Broad-Spectrum Antimicrobial Agents Cornea. Jan, 2012 | Pubmed ID: 22236790 Bacterial Cis-2-unsaturated Fatty Acids Found in the Cystic Fibrosis Airway Modulate Virulence and Persistence of Pseudomonas Aeruginosa The ISME Journal. Dec, 2011 | Pubmed ID: 22134647 Exploiting Dendrimer Multivalency To Combat Emerging and Re-Emerging Infectious Diseases Molecular Pharmaceutics. Dec, 2011 | Pubmed ID: 22126461 2-Heptyl-4-quinolone, a Precursor of the Pseudomonas Quinolone Signal Molecule, Modulates Swarming Motility in Pseudomonas Aeruginosa Journal of Bacteriology. Dec, 2011 | Pubmed ID: 21965567 Step-wise Loss of Bacterial Flagellar Torsion Confers Progressive Phagocytic Evasion PLoS Pathogens. Sep, 2011 | Pubmed ID: 21949654 Systematic Analysis of Diguanylate Cyclases That Promote Biofilm Formation by Pseudomonas Fluorescens Pf0-1 Journal of Bacteriology. Sep, 2011 | Pubmed ID: 21764921 Modulation of Pseudomonas Aeruginosa Surface-associated Group Behaviors by Individual Amino Acids Through C-di-GMP Signaling Research in Microbiology. Sep, 2011 | Pubmed ID: 21554951 A Pseudomonas Aeruginosa Toxin That Hijacks the Host Ubiquitin Proteolytic System PLoS Pathogens. Mar, 2011 | Pubmed ID: 21455491 Non-identity-mediated CRISPR-bacteriophage Interaction Mediated Via the Csy and Cas3 Proteins Journal of Bacteriology. Jul, 2011 | Pubmed ID: 21398535 Structural Basis for C-di-GMP-mediated Inside-out Signaling Controlling Periplasmic Proteolysis PLoS Biology. 2011 | Pubmed ID: 21304926 A C-di-GMP Effector System Controls Cell Adhesion by Inside-out Signaling and Surface Protein Cleavage PLoS Biology. 2011 | Pubmed ID: 21304920 Aminoglycoside Resistance of Pseudomonas Aeruginosa Biofilms Modulated by Extracellular Polysaccharide International Microbiology : the Official Journal of the Spanish Society for Microbiology. Dec, 2010 | Pubmed ID: 21404215 Specific Control of Pseudomonas Aeruginosa Surface-associated Behaviors by Two C-di-GMP Diguanylate Cyclases MBio. 2010 | Pubmed ID: 20978535 Staphylococcus Aureus Resistance on Titanium Coated with Multivalent PEGylated-peptides Biomaterials. Dec, 2010 | Pubmed ID: 20863561 Pseudomonas Aeruginosa Evasion of Phagocytosis is Mediated by Loss of Swimming Motility and is Independent of Flagellum Expression Infection and Immunity. Jul, 2010 | Pubmed ID: 20457788 Antibodies and Immune Effectors: Shaping Gram-negative Bacterial Phenotypes Trends in Microbiology. Jun, 2010 | Pubmed ID: 20359893 Cyclic-di-GMP-mediated Repression of Swarming Motility by Pseudomonas Aeruginosa: the PilY1 Gene and Its Impact on Surface-associated Behaviors Journal of Bacteriology. Jun, 2010 | Pubmed ID: 20233936 Di-adenosine Tetraphosphate (Ap4A) Metabolism Impacts Biofilm Formation by Pseudomonas Fluorescens Via Modulation of C-di-GMP-dependent Pathways Journal of Bacteriology. Jun, 2010 | Pubmed ID: 20154123 Crystal Structure of the Cystic Fibrosis Transmembrane Conductance Regulator Inhibitory Factor Cif Reveals Novel Active-site Features of an Epoxide Hydrolase Virulence Factor Journal of Bacteriology. Apr, 2010 | Pubmed ID: 20118260 Sugar Fatty Acid Esters Inhibit Biofilm Formation by Food-borne Pathogenic Bacteria International Journal of Food Microbiology. Mar, 2010 | Pubmed ID: 20089325 The Pseudomonas Aeruginosa Magnesium Transporter MgtE Inhibits Transcription of the Type III Secretion System Infection and Immunity. Mar, 2010 | Pubmed ID: 20028803 Flagellum-mediated Biofilm Defense Mechanisms of Pseudomonas Aeruginosa Against Host-derived Lactoferrin Infection and Immunity. Oct, 2009 | Pubmed ID: 19651866 Directed Assembly of PEGylated-peptide Coatings for Infection-resistant Titanium Metal Journal of the American Chemical Society. Aug, 2009 | Pubmed ID: 19621876 New Yeast Recombineering Tools for Bacteria Plasmid. Sep, 2009 | Pubmed ID: 19477196 Long-distance Delivery of Bacterial Virulence Factors by Pseudomonas Aeruginosa Outer Membrane Vesicles PLoS Pathogens. Apr, 2009 | Pubmed ID: 19360133 LapD is a Bis-(3',5')-cyclic Dimeric GMP-binding Protein That Regulates Surface Attachment by Pseudomonas Fluorescens Pf0-1 Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009 | Pubmed ID: 19218451 Tobramycin and FDA-approved Iron Chelators Eliminate Pseudomonas Aeruginosa Biofilms on Cystic Fibrosis Cells American Journal of Respiratory Cell and Molecular Biology. Sep, 2009 | Pubmed ID: 19168700 The Developmental Model of Microbial Biofilms: Ten Years of a Paradigm Up for Review Trends in Microbiology. Feb, 2009 | Pubmed ID: 19162483 Interaction Between Bacteriophage DMS3 and Host CRISPR Region Inhibits Group Behaviors of Pseudomonas Aeruginosa Journal of Bacteriology. Jan, 2009 | Pubmed ID: 18952788 Chemotoxicity of Doxorubicin and Surface Expression of P-glycoprotein (MDR1) is Regulated by the Pseudomonas Aeruginosa Toxin Cif American Journal of Physiology. Cell Physiology. Sep, 2008 | Pubmed ID: 18650266 Cif is Negatively Regulated by the TetR Family Repressor CifR Infection and Immunity. Jul, 2008 | Pubmed ID: 18458065 The DeltaF508-CFTR Mutation Results in Increased Biofilm Formation by Pseudomonas Aeruginosa by Increasing Iron Availability American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2008 | Pubmed ID: 18359885 Genetic Evidence for an Alternative Citrate-dependent Biofilm Formation Pathway in Staphylococcus Aureus That is Dependent on Fibronectin Binding Proteins and the GraRS Two-component Regulatory System Infection and Immunity. Jun, 2008 | Pubmed ID: 18347039 Pseudomonas Aeruginosa Biofilm Formation in the Cystic Fibrosis Airway Pulmonary Pharmacology & Therapeutics. Aug, 2008 | Pubmed ID: 18234534 In Vitro Analysis of Tobramycin-treated Pseudomonas Aeruginosa Biofilms on Cystic Fibrosis-derived Airway Epithelial Cells Infection and Immunity. Apr, 2008 | Pubmed ID: 18212077 In Vivo Growth of Pseudomonas Aeruginosa Strains PAO1 and PA14 and the Hypervirulent Strain LESB58 in a Rat Model of Chronic Lung Infection Journal of Bacteriology. Apr, 2008 | Pubmed ID: 18083816 The Flagellum of Pseudomonas Aeruginosa is Required for Resistance to Clearance by Surfactant Protein A PloS One. 2007 | Pubmed ID: 17593964 SadC Reciprocally Influences Biofilm Formation and Swarming Motility Via Modulation of Exopolysaccharide Production and Flagellar Function Journal of Bacteriology. Nov, 2007 | Pubmed ID: 17586642 BifA, a Cyclic-Di-GMP Phosphodiesterase, Inversely Regulates Biofilm Formation and Swarming Motility by Pseudomonas Aeruginosa PA14 Journal of Bacteriology. Nov, 2007 | Pubmed ID: 17586641 Roles for Flagellar Stators in Biofilm Formation by Pseudomonas Aeruginosa Research in Microbiology. Jun, 2007 | Pubmed ID: 17533122 The Pseudomonas Aeruginosa Secreted Protein PA2934 Decreases Apical Membrane Expression of the Cystic Fibrosis Transmembrane Conductance Regulator Infection and Immunity. Aug, 2007 | Pubmed ID: 17502391 Inverse Regulation of Biofilm Formation and Swarming Motility by Pseudomonas Aeruginosa PA14 Journal of Bacteriology. May, 2007 | Pubmed ID: 17337585 Phosphate-dependent Modulation of C-di-GMP Levels Regulates Pseudomonas Fluorescens Pf0-1 Biofilm Formation by Controlling Secretion of the Adhesin LapA Molecular Microbiology. Feb, 2007 | Pubmed ID: 17302799 Vulnerability of Pathogenic Biofilms to Micavibrio Aeruginosavorus Applied and Environmental Microbiology. Jan, 2007 | Pubmed ID: 17098913 Peptide-PEG Amphiphiles As Cytophobic Coatings for Mammalian and Bacterial Cells Chemistry & Biology. Jul, 2006 | Pubmed ID: 16873017 Saccharomyces Cerevisiae-based Molecular Tool Kit for Manipulation of Genes from Gram-negative Bacteria Applied and Environmental Microbiology. Jul, 2006 | Pubmed ID: 16820502 Catheter Lock Solutions Influence Staphylococcal Biofilm Formation on Abiotic Surfaces Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Aug, 2006 | Pubmed ID: 16627606 Biofilm Formation by Pseudomonas Fluorescens WCS365: a Role for LapD Microbiology (Reading, England). May, 2006 | Pubmed ID: 16622054 Conservation of the Pho Regulon in Pseudomonas Fluorescens Pf0-1 Applied and Environmental Microbiology. Mar, 2006 | Pubmed ID: 16517638 Pseudomonas Aeruginosa Inhibits Endocytic Recycling of CFTR in Polarized Human Airway Epithelial Cells American Journal of Physiology. Cell Physiology. Mar, 2006 | Pubmed ID: 16236828 Growing and Analyzing Static Biofilms Current Protocols in Microbiology. Jul, 2005 | Pubmed ID: 18770545 Bacterial Biofilms and Ocular Infections The Ocular Surface. Apr, 2005 | Pubmed ID: 17131010 Biofilms Strike Back Nature Biotechnology. Nov, 2005 | Pubmed ID: 16273068 Pseudomonas Aeruginosa Rhamnolipids Disperse Bordetella Bronchiseptica Biofilms FEMS Microbiology Letters. Sep, 2005 | Pubmed ID: 16098688 Heparin Stimulates Staphylococcus Aureus Biofilm Formation Infection and Immunity. Aug, 2005 | Pubmed ID: 16040971 Susceptibility of Biofilms to Bdellovibrio Bacteriovorus Attack Applied and Environmental Microbiology. Jul, 2005 | Pubmed ID: 16000819 A Three-component Regulatory System Regulates Biofilm Maturation and Type III Secretion in Pseudomonas Aeruginosa Journal of Bacteriology. Feb, 2005 | Pubmed ID: 15687209 Evidence for Two Flagellar Stators and Their Role in the Motility of Pseudomonas Aeruginosa Journal of Bacteriology. Jan, 2005 | Pubmed ID: 15629949 Microbiology: Jekyll or Hide? Nature. Dec, 2004 | Pubmed ID: 15592392 Role of CysE in Production of an Extracellular Signaling Molecule in Providencia Stuartii and Escherichia Coli: Loss of CysE Enhances Biofilm Formation in Escherichia Coli Journal of Bacteriology. Nov, 2004 | Pubmed ID: 15516574 SadB is Required for the Transition from Reversible to Irreversible Attachment During Biofilm Formation by Pseudomonas Aeruginosa PA14 Journal of Bacteriology. Jul, 2004 | Pubmed ID: 15231779 Isolation and Characterization of a Generalized Transducing Phage for Pseudomonas Aeruginosa Strains PAO1 and PA14 Journal of Bacteriology. May, 2004 | Pubmed ID: 15126493 A Genetic Basis for Pseudomonas Aeruginosa Biofilm Antibiotic Resistance Nature. Nov, 2003 | Pubmed ID: 14628055 Transition from Reversible to Irreversible Attachment During Biofilm Formation by Pseudomonas Fluorescens WCS365 Requires an ABC Transporter and a Large Secreted Protein Molecular Microbiology. Aug, 2003 | Pubmed ID: 12890017 Alginate is Not a Significant Component of the Extracellular Polysaccharide Matrix of PA14 and PAO1 Pseudomonas Aeruginosa Biofilms Proceedings of the National Academy of Sciences of the United States of America. Jun, 2003 | Pubmed ID: 12810959 To Build a Biofilm Journal of Bacteriology. May, 2003 | Pubmed ID: 12700246 Rhamnolipid Surfactant Production Affects Biofilm Architecture in Pseudomonas Aeruginosa PAO1 Journal of Bacteriology. Feb, 2003 | Pubmed ID: 12533479 Microbiology: a Resistance Switch Nature. Apr, 2002 | Pubmed ID: 11961541 Ek Oksijenin Kistik Fibrozis Hava Yolu Mikrobiyomu Üzerindeki Etkisini Incelemek için Bir Modelin Tasarımı ve Geliştirilmesi Jacob Vieira1, Tara Gallagher2, Hui-Yu Sui1, Sirus Jesudasen3, Katrine Whiteson2, George A. O'Toole4, Kurt Hanselmann5, Peggy S. Lai1 1Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, 2Department of Molecular Biology & Biochemistry, University of California, Irvine, 3Department of Medicine, Massachusetts General Hospital, 4Department of Microbiology & Immunology, Geisel School of Medicine at Dartmouth, 5Swiss i-research and teaching institute JoVE 62888 Medicine Microtiter Bulaşık Biyofilm Oluşumu Testi George A. O'Toole1 1Microbiology and Immunology, Dartmouth Medical School JoVE 2437 Immunology and Infection
Ek Oksijenin Kistik Fibrozis Hava Yolu Mikrobiyomu Üzerindeki Etkisini Incelemek için Bir Modelin Tasarımı ve Geliştirilmesi Jacob Vieira1, Tara Gallagher2, Hui-Yu Sui1, Sirus Jesudasen3, Katrine Whiteson2, George A. O'Toole4, Kurt Hanselmann5, Peggy S. Lai1 1Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, 2Department of Molecular Biology & Biochemistry, University of California, Irvine, 3Department of Medicine, Massachusetts General Hospital, 4Department of Microbiology & Immunology, Geisel School of Medicine at Dartmouth, 5Swiss i-research and teaching institute JoVE 62888 Medicine
Microtiter Bulaşık Biyofilm Oluşumu Testi George A. O'Toole1 1Microbiology and Immunology, Dartmouth Medical School JoVE 2437 Immunology and Infection
