In JoVE (1)
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Articles by Gerben Ferwerda in JoVE
An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection Marloes Vissers1, Marrit N. Habets1, Inge M. L. Ahout1, Jop Jans1, Marien I. de Jonge1, Dimitri A. Diavatopoulos1, Gerben Ferwerda1 1Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud university medical center Human respiratory syncytial virus (HRSV) can cause severe bronchiolitis in young infants. Part of the pathogenesis of severe HRSV disease is caused by the host immune response. Stimulation of primary human immune cells with HRSV provides a fast and reproducible model system to study activation of inflammatory pathways and infection.