Gijs R. Van den Brink

Publications

• Findings from a Randomized Controlled Trial of Fecal Transplantation for Patients with Ulcerative Colitis
  Gastroenterology. Mar, 2015  |   Pubmed ID: 25836986
• Safety and Feasability of Using the Second-Generation Pillcam Colon Capsule to Assess Active Colonic Crohn's Disease
  Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Mar, 2015  |   Pubmed ID: 25804331
• HDAC1 and HDAC2 Collectively Regulate Intestinal Stem Cell Homeostasis
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2015  |   Pubmed ID: 25648995
• Stromal Indian Hedgehog Signaling is Required for Intestinal Adenoma Formation in Mice
  Gastroenterology. Jan, 2015  |   Pubmed ID: 25307863
• ER Stress Induces Epithelial Differentiation in the Mouse Oesophagus
  Gut. Feb, 2015  |   Pubmed ID: 24789843
• Azathioprine Does Not Reduce Adenoma Formation in a Mouse Model of Sporadic Intestinal Tumorigenesis
  World Journal of Gastroenterology : WJG. Nov, 2014  |   Pubmed ID: 25469037
• Sex Disparity in Colonic Adenomagenesis Involves Promotion by Male Hormones, Not Protection by Female Hormones
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2014  |   Pubmed ID: 25368192
• Length of Hospital Stay and Associated Hospital Costs with Infliximab Versus Cyclosporine in Severe Ulcerative Colitis
  European Journal of Gastroenterology & Hepatology. Nov, 2014  |   Pubmed ID: 25171024
• Repurposing Miltefosine for the Treatment of Immune-mediated Disease?
  The Journal of Pharmacology and Experimental Therapeutics. Aug, 2014  |   Pubmed ID: 24833702
• Loss of SMAD4 Alters BMP Signaling to Promote Colorectal Cancer Cell Metastasis Via Activation of Rho and ROCK
  Gastroenterology. Jul, 2014  |   Pubmed ID: 24704720
• Vitamin D Deficiency in Crohn's Disease and Healthy Controls: a Prospective Case-control Study in the Netherlands
  Journal of Crohn's & Colitis. Oct, 2014  |   Pubmed ID: 24666975
• Effects of Infliximab Retreatment After Consecutive Discontinuation of Infliximab and Adalimumab in Refractory Crohn's Disease
  Inflammatory Bowel Diseases. Feb, 2014  |   Pubmed ID: 24378599
• Selective Inhibition of Mucosal Serotonin As Treatment for IBD?
  Gut. Jun, 2014  |   Pubmed ID: 23868328
• Oestrogens Promote Tumorigenesis in a Mouse Model for Colitis-associated Cancer
  Gut. Feb, 2014  |   Pubmed ID: 23408349
• Miltefosine Suppresses Inflammation in a Mouse Model of Inflammatory Bowel Disease
  Inflammatory Bowel Diseases. Aug, 2013  |   Pubmed ID: 23811637
• Superantigen-induced Steroid Resistance Depends on Activation of Phospholipase Cβ2
  Journal of Immunology (Baltimore, Md. : 1950). Jun, 2013  |   Pubmed ID: 23690479
• ER Stress Causes Rapid Loss of Intestinal Epithelial Stemness Through Activation of the Unfolded Protein Response
  Cell Reports. Apr, 2013  |   Pubmed ID: 23545496
• Foxf2: a Mesenchymal Regulator of Intestinal Adenoma Development
  Gastroenterology. May, 2013  |   Pubmed ID: 23523844
• Biosimilars in IBD: Hope or Expectation?
  Gut. Jun, 2013  |   Pubmed ID: 23503043
• Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-cell-like Properties
  Cell. Jan, 2013  |   Pubmed ID: 23273993
• Inactivation of Patched1 in Mice Leads to Development of Gastrointestinal Stromal-like Tumors That Express Pdgfrα but Not Kit
  Gastroenterology. Jan, 2013  |   Pubmed ID: 23041331
• Impaired Autophagy Leads to Abnormal Dendritic Cell-epithelial Cell Interactions
  Journal of Crohn's & Colitis. Aug, 2013  |   Pubmed ID: 22981596
• Hedgehog Signalling Stimulates Precursor Cell Accumulation and Impairs Epithelial Maturation in the Murine Oesophagus
  Gut. Mar, 2013  |   Pubmed ID: 22504664
• Rage Mediated DAMP Signaling in Intestinal Tumorigenesis
  Oncoimmunology. Oct, 2012  |   Pubmed ID: 23170266
• Hedgehog Signaling and Maintenance of Homeostasis in the Intestinal Epithelium
  Physiology (Bethesda, Md.). Jun, 2012  |   Pubmed ID: 22689790
• Asb11 is a Regulator of Embryonic and Adult Regenerative Myogenesis
  Stem Cells and Development. Nov, 2012  |   Pubmed ID: 22512762
• Autophagy Attenuates the Adaptive Immune Response by Destabilizing the Immunologic Synapse
  Gastroenterology. Jun, 2012  |   Pubmed ID: 22370477
• A Major Advance in Ex Vivo Intestinal Organ Culture
  Gut. Jul, 2012  |   Pubmed ID: 22315470
• 5-Aminosalicylic Acid Inhibits Cell Cycle Progression in a Phospholipase D Dependent Manner in Colorectal Cancer
  Gut. Dec, 2012  |   Pubmed ID: 22187071
• Regulatory Macrophages Induced by Infliximab Are Involved in Healing in Vivo and in Vitro
  Inflammatory Bowel Diseases. Mar, 2012  |   Pubmed ID: 21936028
• Pretreatment with Interferon-γ Enhances the Therapeutic Activity of Mesenchymal Stromal Cells in Animal Models of Colitis
  Stem Cells (Dayton, Ohio). Oct, 2011  |   Pubmed ID: 21898680
• Blimp1 Regulates the Transition of Neonatal to Adult Intestinal Epithelium
  Nature Communications. 2011  |   Pubmed ID: 21878906
• Mesenchymal Stromal Cell Function is Not Affected by Drugs Used in the Treatment of Inflammatory Bowel Disease
  Cytotherapy. Oct, 2011  |   Pubmed ID: 21846292
• Intestinal Tumorigenesis is Not Affected by Progesterone Signaling in Rodent Models
  PloS One. 2011  |   Pubmed ID: 21818351
• Statins Augment the Chemosensitivity of Colorectal Cancer Cells Inducing Epigenetic Reprogramming and Reducing Colorectal Cancer Cell 'stemness' Via the Bone Morphogenetic Protein Pathway
  Gut. Nov, 2011  |   Pubmed ID: 21551187
• Neutralizing Antibodies Against Adeno-associated Viruses in Inflammatory Bowel Disease Patients: Implications for Gene Therapy
  Inflammatory Bowel Diseases. Dec, 2011  |   Pubmed ID: 21370319
• FXR Activation Inhibits Inflammation and Preserves the Intestinal Barrier in IBD
  Gut. Apr, 2011  |   Pubmed ID: 21270116
• Anti-tumor Necrosis Factor-α Antibodies Induce Regulatory Macrophages in an Fc Region-dependent Manner
  Gastroenterology. Jan, 2011  |   Pubmed ID: 20955706
• Morphogens and the Parietal Cell: Shaping Up Acid Secretion
  Gastroenterology. Dec, 2010  |   Pubmed ID: 21029799
• Autologous Bone Marrow-derived Mesenchymal Stromal Cell Treatment for Refractory Luminal Crohn's Disease: Results of a Phase I Study
  Gut. Dec, 2010  |   Pubmed ID: 20921206
• Cyclin D2-cyclin-dependent Kinase 4/6 is Required for Efficient Proliferation and Tumorigenesis Following Apc Loss
  Cancer Research. Oct, 2010  |   Pubmed ID: 20736363
• Loss of Indian Hedgehog Activates Multiple Aspects of a Wound Healing Response in the Mouse Intestine
  Gastroenterology. Nov, 2010  |   Pubmed ID: 20682322
• The Role of EZH2 and DNA Methylation in the Silencing of the Tumour Suppressor RUNX3 in Colorectal Cancer
  Carcinogenesis. Sep, 2010  |   Pubmed ID: 20631058
• The Absence of Functional PI3Kgamma Prevents Leukocyte Recruitment and Ameliorates DSS-induced Colitis in Mice
  Immunology Letters. Jun, 2010  |   Pubmed ID: 20347874
• Sonic Hedgehog: a Link Between Inflammation, Gastric Atrophy, and Acid Suppression?
  Gastroenterology. Feb, 2010  |   Pubmed ID: 20034600
• Quality of Web-based Information on Inflammatory Bowel Diseases
  Inflammatory Bowel Diseases. Dec, 2009  |   Pubmed ID: 19462423
• Depletion of the Colonic Epithelial Precursor Cell Compartment Upon Conditional Activation of the Hedgehog Pathway
  Gastroenterology. Jun, 2009  |   Pubmed ID: 19272384
• Cytokine Responses in Very Low Birth Weight Infants Receiving Glutamine-enriched Enteral Nutrition
  Journal of Pediatric Gastroenterology and Nutrition. Jan, 2009  |   Pubmed ID: 19172131
• Bone Morphogenetic Protein Signalling in Colorectal Cancer
  Nature Reviews. Cancer. Oct, 2008  |   Pubmed ID: 18756288
• Die Knochen Morphogenetische Protein-Pathway Ist in Den Meisten Sporadischen Colorectal Krebse Inaktiviert
  Gastroenterology. May, 2008  |   Pubmed ID: 18471510
• The Bone Morphogenetic Protein Pathway is Active in Human Colon Adenomas and Inactivated in Colorectal Cancer
  Cancer. Jan, 2008  |   Pubmed ID: 18008360
• Hedgehog Signaling in Development and Homeostasis of the Gastrointestinal Tract
  Physiological Reviews. Oct, 2007  |   Pubmed ID: 17928586
• The Effect of Statins in Colorectal Cancer is Mediated Through the Bone Morphogenetic Protein Pathway
  Gastroenterology. Oct, 2007  |   Pubmed ID: 17919499
• Bone Morphogenetic Protein Signaling Suppresses Tumorigenesis at Gastric Epithelial Transition Zones in Mice
  Cancer Research. Sep, 2007  |   Pubmed ID: 17804727
• Glucocorticoid Signaling: a Nongenomic Mechanism for T-cell Immunosuppression
  Trends in Molecular Medicine. Apr, 2007  |   Pubmed ID: 17293163
• The Morphogenetic Code and Colon Cancer Development
  Cancer Cell. Feb, 2007  |   Pubmed ID: 17292823
• Bone Morphogenetic Protein-2 is a Negative Regulator of Hepatocyte Proliferation Downregulated in the Regenerating Liver
  World Journal of Gastroenterology : WJG. Dec, 2006  |   Pubmed ID: 17171790
• Expression of Hedgehog Pathway Components in the Adult Colon
  Gastroenterology. Feb, 2006  |   Pubmed ID: 16472622
• Down-regulation of a Morphogen (sonic Hedgehog) Gradient in the Gastric Epithelium of Helicobacter Pylori-infected Mongolian Gerbils
  The Journal of Pathology. Jun, 2005  |   Pubmed ID: 15818572
• Hh Pathway Expression in Human Gut Tissues and in Inflammatory Gut Diseases
  Laboratory Investigation; a Journal of Technical Methods and Pathology. Dec, 2004  |   Pubmed ID: 15502857
• Linking Pathways in Colorectal Cancer
  Nature Genetics. Oct, 2004  |   Pubmed ID: 15454939
• Regulatory Regions in the Rat Lactase-phlorizin Hydrolase Gene That Control Cell-specific Expression
  Journal of Pediatric Gastroenterology and Nutrition. Sep, 2004  |   Pubmed ID: 15319629
• DNA Array Analysis of the Effects of Aspirin on Colon Cancer Cells: Involvement of Rac1
  Carcinogenesis. Jul, 2004  |   Pubmed ID: 14976132
• Indian Hedgehog is an Antagonist of Wnt Signaling in Colonic Epithelial Cell Differentiation
  Nature Genetics. Mar, 2004  |   Pubmed ID: 14770182
• Bone Morphogenetic Protein 2 is Expressed By, and Acts Upon, Mature Epithelial Cells in the Colon
  Gastroenterology. Jan, 2004  |   Pubmed ID: 14699493
• Infliximab but Not Etanercept Induces Apoptosis in Lamina Propria T-lymphocytes from Patients with Crohn's Disease
  Gastroenterology. Jun, 2003  |   Pubmed ID: 12806611
• Conscious Sedation for EUS of the Esophagus and Stomach: a Double-blind, Randomized, Controlled Trial Comparing Midazolam with Placebo
  Gastrointestinal Endoscopy. Jun, 2003  |   Pubmed ID: 12776030
• From Extracellular to Intracellular Targets, Inhibiting MAP Kinases in Treatment of Crohn's Disease
  Annals of the New York Academy of Sciences. Nov, 2002  |   Pubmed ID: 12485892
• Feed a Cold, Starve a Fever?
  Clinical and Diagnostic Laboratory Immunology. Jan, 2002  |   Pubmed ID: 11777851