Gillian Farnie Institute of Cancer Sciences University of Manchester Biography Publications Institution JoVE Articles Gillian Farnie has not added a biography. If you are Gillian Farnie and would like to personalize this page please email our Author Liaison for assistance. Publications Erratum To: Patient-Derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis Journal of Mammary Gland Biology and Neoplasia. Dec, 2016 | Pubmed ID: 27815673 Patient-derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis Journal of Mammary Gland Biology and Neoplasia. Dec, 2016 | Pubmed ID: 27680982 Three-dimensional Modelling Identifies Novel Genetic Dependencies Associated with Breast Cancer Progression in the Isogenic MCF10 Model The Journal of Pathology. Nov, 2016 | Pubmed ID: 27512948 High Mitochondrial Mass Identifies a Sub-population of Stem-like Cancer Cells That Are Chemo-resistant Oncotarget. Oct, 2015 | Pubmed ID: 26421710 Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity Cell Reports. Sep, 2015 | Pubmed ID: 26387946 Focal Adhesion Kinase and Wnt Signaling Regulate Human Ductal Carcinoma in Situ Stem Cell Activity and Response to Radiotherapy Stem Cells (Dayton, Ohio). Feb, 2015 | Pubmed ID: 25187396 A Differential Role for CXCR4 in the Regulation of Normal Versus Malignant Breast Stem Cell Activity Oncotarget. Feb, 2014 | Pubmed ID: 24583601 Lapatinib Inhibits Stem/progenitor Proliferation in Preclinical in Vitro Models of Ductal Carcinoma in Situ (DCIS) Cell Cycle (Georgetown, Tex.). 2014 | Pubmed ID: 24247151 Recent Advances Reveal IL-8 Signaling As a Potential Key to Targeting Breast Cancer Stem Cells Breast Cancer Research : BCR. 2013 | Pubmed ID: 24041156 Combined Inhibition of ErbB1/2 and Notch Receptors Effectively Targets Breast Ductal Carcinoma in Situ (DCIS) Stem/progenitor Cell Activity Regardless of ErbB2 Status PloS One. 2013 | Pubmed ID: 23457626 Targeting CXCR1/2 Significantly Reduces Breast Cancer Stem Cell Activity and Increases the Efficacy of Inhibiting HER2 Via HER2-dependent and -independent Mechanisms Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2013 | Pubmed ID: 23149820 A Detailed Mammosphere Assay Protocol for the Quantification of Breast Stem Cell Activity Journal of Mammary Gland Biology and Neoplasia. Jun, 2012 | Pubmed ID: 22665270 P-Cadherin is Co-Expressed with Cd44 and Cd49f and Mediates Stem Cell Properties in Basal-Like Breast Cancer Stem Cells (Dayton, Ohio). Mar, 2012 | Pubmed ID: 22389315 Breast Cancer Stem Cells and Their Role in Resistance to Endocrine Therapy Hormones & Cancer. Apr, 2011 | Pubmed ID: 21761332 Breast Cancer Stem Cells: Something out of Notching? Cancer Research. Nov, 2010 | Pubmed ID: 21045140 Regulation of Breast Cancer Stem Cell Activity by Signaling Through the Notch4 Receptor Cancer Research. Jan, 2010 | Pubmed ID: 20068161 Resistance to Endocrine Therapy: Are Breast Cancer Stem Cells the Culprits? Journal of Mammary Gland Biology and Neoplasia. Mar, 2009 | Pubmed ID: 19252972 Are Stem-like Cells Responsible for Resistance to Therapy in Breast Cancer? Breast Disease. 2008 | Pubmed ID: 19029627 Prolactin Receptor Antagonism Reduces the Clonogenic Capacity of Breast Cancer Cells and Potentiates Doxorubicin and Paclitaxel Cytotoxicity Breast Cancer Research : BCR. 2008 | Pubmed ID: 18681966 Mammary Stem Cells and Breast Cancer--role of Notch Signalling Stem Cell Reviews. Jun, 2007 | Pubmed ID: 17873349 Novel Cell Culture Technique for Primary Ductal Carcinoma in Situ: Role of Notch and Epidermal Growth Factor Receptor Signaling Pathways Journal of the National Cancer Institute. Apr, 2007 | Pubmed ID: 17440163 Small-molecule Inhibitors of the MDM2-p53 Protein-protein Interaction Based on an Isoindolinone Scaffold Journal of Medicinal Chemistry. Oct, 2006 | Pubmed ID: 17034127 Isoindolinone-based Inhibitors of the MDM2-p53 Protein-protein Interaction Bioorganic & Medicinal Chemistry Letters. Mar, 2005 | Pubmed ID: 15713419 The Mitogenic Action of Insulin-like Growth Factor I in Normal Human Mammary Epithelial Cells Requires the Epidermal Growth Factor Receptor Tyrosine Kinase The Journal of Biological Chemistry. Jan, 2004 | Pubmed ID: 14593113 उपयोग कार्यात्मक जीनोमिक्स स्क्रीनिंग कैंसर सेल उपगोल संस्कृतियों में संभावित उपन्यास ड्रग लक्ष्यों की पहचान करने के लिए Eamonn Morrison1,2, Patty Wai1,2, Andri Leonidou1,2, Philip Bland1,2, Saira Khalique1,2, Gillian Farnie3, Frances Daley1, Barrie Peck1,2, Rachael Natrajan1,2 1The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer, The Institute of Cancer Research, 2Division of Molecular Pathology, The Institute of Cancer Research, 3Institute of Cancer Sciences, University of Manchester Cancer Research
उपयोग कार्यात्मक जीनोमिक्स स्क्रीनिंग कैंसर सेल उपगोल संस्कृतियों में संभावित उपन्यास ड्रग लक्ष्यों की पहचान करने के लिए Eamonn Morrison1,2, Patty Wai1,2, Andri Leonidou1,2, Philip Bland1,2, Saira Khalique1,2, Gillian Farnie3, Frances Daley1, Barrie Peck1,2, Rachael Natrajan1,2 1The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer, The Institute of Cancer Research, 2Division of Molecular Pathology, The Institute of Cancer Research, 3Institute of Cancer Sciences, University of Manchester Cancer Research
