Giuseppe Pantaleo

Publications

• Antigenic Competition in CD4 T Cell Responses in a Randomized, Multicenter, Double-blind Clinical HIV Vaccine Trial
  Science Translational Medicine. Nov, 2019  |   Pubmed ID: 31748227
• Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01
  Cell Host & Microbe. 11, 2019  |   Pubmed ID: 31653484
• Development of a Novel Human Phage Display-derived Anti-LAG3 ScFv Antibody Targeting CD8 T Lymphocyte Exhaustion
  BMC Biotechnology. 10, 2019  |   Pubmed ID: 31623599
• Safety and Immunogenicity of a Multivalent HIV Vaccine Comprising Envelope Protein with Either DNA or NYVAC Vectors (HVTN 096): a Phase 1b, Double-blind, Placebo-controlled Trial
  The Lancet. HIV. Nov, 2019  |   Pubmed ID: 31601541
• DNA Priming and Gp120 Boosting Induces HIV-specific Antibodies in a Randomized Clinical Trial
  The Journal of Clinical Investigation. Nov, 2019  |   Pubmed ID: 31566579
• Safety and Tolerance of Lymph Node Biopsies from Chronic HIV-1 Volunteers in Rural Tanzania
  BMC Research Notes. Sep, 2019  |   Pubmed ID: 31492170
• Lymph Node Migratory Dendritic Cells Modulate HIV-1 Transcription Through PD-1 Engagement
  PLoS Pathogens. Jul, 2019  |   Pubmed ID: 31329640
• Tumor Suppression of Novel Anti-PD-1 Antibodies Mediated Through CD28 Costimulatory Pathway
  The Journal of Experimental Medicine. Jul, 2019  |   Pubmed ID: 31123083
• Multi-arm, Multi-stage Randomised Controlled Trials for Evaluating Therapeutic HIV Cure Interventions
  The Lancet. HIV. May, 2019  |   Pubmed ID: 31047670
• Detection of Antisense Protein (ASP) RNA Transcripts in Individuals Infected with Human Immunodeficiency Virus Type 1 (HIV-1)
  The Journal of General Virology. May, 2019  |   Pubmed ID: 30896385
• Re-boost Immunizations with the Peptide-based Therapeutic HIV Vaccine, Vacc-4x, Restores Geometric Mean Viral Load Set-point During Treatment Interruption
  PloS One. 2019  |   Pubmed ID: 30699178
• HIV Infection Functionally Impairs Mycobacterium Tuberculosis-Specific CD4 and CD8 T-Cell Responses
  Journal of Virology. 03, 2019  |   Pubmed ID: 30541853
• Comparative Analysis and Generation of a Robust HIV-1 DNA Quantification Assay
  Journal of Virological Methods. 01, 2019  |   Pubmed ID: 30326210
• Antibodies to and Reproductive Health Issues in Women with SLE: a Case-control Study
  Lupus Science & Medicine. 2018  |   Pubmed ID: 30538819
• Immunogenicity and Safety of Double Versus Standard Dose of the Seasonal Influenza Vaccine in Solid-organ Transplant Recipients: A Randomized Controlled Trial
  Vaccine. 10, 2018  |   Pubmed ID: 30181045
• TLR3 Agonist and CD40-targeting Vaccination Induces Immune Responses and Reduces HIV-1 Reservoirs
  The Journal of Clinical Investigation. 10, 2018  |   Pubmed ID: 30148455
• CD32 and PD-1 Lymph Node CD4 T Cells Support Persistent HIV-1 Transcription in Treated Aviremic Individuals
  Journal of Virology. 10, 2018  |   Pubmed ID: 29976671
• Hyperglycaemia is Inversely Correlated with Live M. Bovis BCG-specific CD4 T Cell Responses in Tanzanian Adults with Latent or Active Tuberculosis
  Immunity, Inflammation and Disease. 06, 2018  |   Pubmed ID: 29642283
• Immunogenicity of NYVAC Prime-Protein Boost Human Immunodeficiency Virus Type 1 Envelope Vaccination and Simian-Human Immunodeficiency Virus Challenge of Nonhuman Primates
  Journal of Virology. 04, 2018  |   Pubmed ID: 29437967
• HIV-1 Envelope Glycoproteins from Diverse Clades Differentiate Antibody Responses and Durability Among Vaccinees
  Journal of Virology. 04, 2018  |   Pubmed ID: 29386288
• Cell-Mediated Immune Predictors of Vaccine Effect on Viral Load and CD4 Count in a Phase 2 Therapeutic HIV-1 Vaccine Clinical Trial
  EBioMedicine. Oct, 2017  |   Pubmed ID: 28970080
• Targeted Immune Interventions for an HIV-1 Cure
  Trends in Molecular Medicine. 10, 2017  |   Pubmed ID: 28890135
• Mixed Th1 and Th2 Mycobacterium Tuberculosis-specific CD4 T Cell Responses in Patients with Active Pulmonary Tuberculosis from Tanzania
  PLoS Neglected Tropical Diseases. Jul, 2017  |   Pubmed ID: 28759590
• B-cell Abnormalities and Impact on Antibody Response in HIV Infection
  Current Opinion in HIV and AIDS. May, 2017  |   Pubmed ID: 28422784
• Follicular CD8 T Cells Accumulate in HIV Infection and Can Kill Infected Cells in Vitro Via Bispecific Antibodies
  Science Translational Medicine. 01, 2017  |   Pubmed ID: 28100833
• Therapeutic Vaccines and Immunological Intervention in HIV Infection: a Paradigm Change
  Current Opinion in HIV and AIDS. 11, 2016  |   Pubmed ID: 27607591
• PD-1(+) and Follicular Helper T Cells Are Responsible for Persistent HIV-1 Transcription in Treated Aviremic Individuals
  Nature Medicine. 07, 2016  |   Pubmed ID: 27239760
• Clinically-relevant Threshold of Preformed Donor-specific Anti-HLA Antibodies in Kidney Transplantation
  Human Immunology. Jun, 2016  |   Pubmed ID: 27085791
• A Case for PreART-adjusted Endpoints in HIV Therapeutic Vaccine Trials
  Vaccine. Mar, 2016  |   Pubmed ID: 26826543
• Immune Correlates of Vaccine Protection Against HIV-1 Acquisition
  Science Translational Medicine. Oct, 2015  |   Pubmed ID: 26491081
• The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo
  PLoS Pathogens. Sep, 2015  |   Pubmed ID: 26379282
• Combined Use of Mycobacterium Tuberculosis-specific CD4 and CD8 T-cell Responses is a Powerful Diagnostic Tool of Active Tuberculosis
  Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Feb, 2015  |   Pubmed ID: 25362202
• Exhaustion of Bacteria-specific CD4 T Cells and Microbial Translocation in Common Variable Immunodeficiency Disorders
  The Journal of Experimental Medicine. Sep, 2014  |   Pubmed ID: 25225461
• Immune Activation Alters Cellular and Humoral Responses to Yellow Fever 17D Vaccine
  The Journal of Clinical Investigation. Jul, 2014  |   Pubmed ID: 24911151
• The Immune Space: a Concept and Template for Rationalizing Vaccine Development
  AIDS Research and Human Retroviruses. Nov, 2014  |   Pubmed ID: 24857015
• Safety and Efficacy of the Peptide-based Therapeutic Vaccine for HIV-1, Vacc-4x: a Phase 2 Randomised, Double-blind, Placebo-controlled Trial
  The Lancet. Infectious Diseases. Apr, 2014  |   Pubmed ID: 24525316
• Rapid Perturbation in Viremia Levels Drives Increases in Functional Avidity of HIV-specific CD8 T Cells
  PLoS Pathogens. 2013  |   Pubmed ID: 23853580
• Vaccine and Immunotherapeutic Interventions
  Current Opinion in HIV and AIDS. May, 2013  |   Pubmed ID: 23478912
• Inadequate T Follicular Cell Help Impairs B Cell Immunity During HIV Infection
  Nature Medicine. Apr, 2013  |   Pubmed ID: 23475201
• Follicular Helper T Cells Serve As the Major CD4 T Cell Compartment for HIV-1 Infection, Replication, and Production
  The Journal of Experimental Medicine. Jan, 2013  |   Pubmed ID: 23254284
• NYVAC Immunization Induces Polyfunctional HIV-specific T-cell Responses in Chronically-infected, ART-treated HIV Patients
  European Journal of Immunology. Nov, 2012  |   Pubmed ID: 22930439
• A Novel HIV Vaccine Adjuvanted by IC31 Induces Robust and Persistent Humoral and Cellular Immunity
  PloS One. 2012  |   Pubmed ID: 22848738
• The Number of Toll-like Receptor 9-agonist Motifs in the Adenovirus Genome Correlates with Induction of Dendritic Cell Maturation by Adenovirus Immune Complexes
  Journal of Virology. Jun, 2012  |   Pubmed ID: 22491454
• Modulation of Human Memory T-cell Function by Different Antigen-presenting Cells
  European Journal of Immunology. Mar, 2012  |   Pubmed ID: 22144294
• Poxvirus Vector-based HIV Vaccines
  Current Opinion in HIV and AIDS. Sep, 2010  |   Pubmed ID: 20978379
• Long Sequence Duplications, Repeats, and Palindromes in HIV-1 Gp120: Length Variation in V4 As the Product of Misalignment Mechanism
  Virology. Mar, 2010  |   Pubmed ID: 20106497
• Functional Signatures in Antiviral T-cell Immunity for Monitoring Virus-associated Diseases
  Nature Reviews. Immunology. May, 2006  |   Pubmed ID: 16622477