Other Publications (1)
Articles by Haley C. Cropper in JoVE
PET Imaging of Neuroinflammation Using [11C]DPA-713 in a Mouse Model of Ischemic Stroke Aisling M. Chaney1, Emily M. Johnson1, Haley C. Cropper1, Michelle L. James1,2 1Department of Radiology, Stanford University, 2Department of Neurology and Neurological Sciences, Stanford University Positron Emission Tomography (PET) imaging of translocator protein 18 kDa (TSPO) provides a non-invasive means to visualize the dynamic role of neuroinflammation in the development and progression of brain diseases. This protocol describes TSPO-PET and ex vivo autoradiography to detect neuroinflammation in a mouse model of ischemic stroke.
Other articles by Haley C. Cropper on PubMed
[F]FSPG-PET Reveals Increased Cystine/glutamate Antiporter (xc-) Activity in a Mouse Model of Multiple Sclerosis Journal of Neuroinflammation. Feb, 2018 | Pubmed ID: 29471880 The cystine/glutamate antiporter (xc-) has been implicated in several neurological disorders and, specifically, in multiple sclerosis (MS) as a mediator of glutamate excitotoxicity and proinflammatory immune responses. We aimed to evaluate an xc-specific positron emission tomography (PET) radiotracer, (4S)-4-(3-[F]fluoropropyl)-L-glutamate ([F]FSPG), for its ability to allow non-invasive monitoring of xc- activity in a mouse model of MS.