Hanbin Mao Department of Chemistry & Biochemistry Kent State University Biography Publications Institution JoVE Articles Hanbin Mao has not added a biography. If you are Hanbin Mao and would like to personalize this page please email our Author Liaison for assistance. Publications Short LNA-modified Oligonucleotide Probes As Efficient Disruptors of DNA G-quadruplexes Nucleic Acids Research. Jul, 2022 | Pubmed ID: 35801856 Single-molecule Displacement Assay Reveals Strong Binding of Polyvalent Dendrimer Ligands to Telomeric G-quadruplex Analytical Biochemistry. 07, 2022 | Pubmed ID: 35500657 Single-Molecule Mechanochemical Sensing Accounts of Chemical Research. 05, 2022 | Pubmed ID: 35420417 Small Molecules Modulate Liquid-to-Solid Transitions in Phase-Separated Tau Condensates Angewandte Chemie (International Ed. in English). 06, 2022 | Pubmed ID: 35320624 Dissection of Nanoconfinement and Proximity Effects on the Binding Events in DNA Origami Nanocavity Nucleic Acids Research. 01, 2022 | Pubmed ID: 35037040 Chirality Transmission in Macromolecular Domains Nature Communications. 01, 2022 | Pubmed ID: 35013247 Direct Measurement of Intermolecular Mechanical Force for Nonspecific Interactions Between Small Molecules The Journal of Physical Chemistry Letters. Nov, 2021 | Pubmed ID: 34780182 Correction: DNA Origami Nano-mechanics Chemical Society Reviews. Nov, 2021 | Pubmed ID: 34549206 Measurement of Single-Molecule Forces in Cholesterol and Cyclodextrin Host-Guest Complexes The Journal of Physical Chemistry. B. 10, 2021 | Pubmed ID: 34523939 DNA Origami Nano-mechanics Chemical Society Reviews. Nov, 2021 | Pubmed ID: 34499072 Mechanical Unfolding of Ensemble Biomolecular Structures by Shear Force Chemical Science. Aug, 2021 | Pubmed ID: 34377405 Mechanochemical Properties of DNA Origami Nanosprings Revealed by Force Jumps in Optical Tweezers Nanoscale. May, 2021 | Pubmed ID: 33908965 Chemo-Mechanical Modulation of Cell Motions Using DNA Nanosprings Bioconjugate Chemistry. 02, 2021 | Pubmed ID: 33475341 Cooperative Heteroligand Interaction with G-Quadruplexes Shows Evidence of Allosteric Binding Biochemistry. 09, 2020 | Pubmed ID: 32833433 Ensemble Sensing Using Single-Molecule DNA Copolymers Analytical Chemistry. 10, 2020 | Pubmed ID: 32829637 A Poly(thymine)-melamine Duplex for the Assembly of DNA Nanomaterials Nature Materials. 09, 2020 | Pubmed ID: 32661383 Detecting the Coronavirus (COVID-19) ACS Sensors. 08, 2020 | Pubmed ID: 32627534 Duplex DNA Is Weakened in Nanoconfinement Journal of the American Chemical Society. 06, 2020 | Pubmed ID: 32383870 Chaperone-Assisted Host-Guest Interactions Revealed by Single-Molecule Force Spectroscopy Journal of the American Chemical Society. 11, 2019 | Pubmed ID: 31679339 Single-Molecule Topochemical Analyses for Large-Scale Multiplexing Tasks Analytical Chemistry. 11, 2019 | Pubmed ID: 31553880 Single-Molecule Investigations of G-Quadruplex Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 31444756 Single-Molecule Mechanochemical Sensing Using DNA Origami Nanostructures Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 31309481 Submolecular Dissection Reveals Strong and Specific Binding of Polyamide-pyridostatin Conjugates to Human Telomere Interface Nucleic Acids Research. 04, 2019 | Pubmed ID: 30820532 Binding of a Telomestatin Derivative Changes the Mechanical Anisotropy of a Human Telomeric G-Quadruplex Angewandte Chemie (International Ed. in English). 01, 2019 | Pubmed ID: 30476359 Random Formation of G-Quadruplexes in the Full-Length Human Telomere Overhangs Leads to a Kinetic Folding Pattern with Targetable Vacant G-Tracts Biochemistry. 12, 2018 | Pubmed ID: 30480434 Decreased Water Activity in Nanoconfinement Contributes to the Folding of G-quadruplex and I-motif Structures Proceedings of the National Academy of Sciences of the United States of America. 09, 2018 | Pubmed ID: 30181280 Mechanical Cooperativity in DNA Cruciform Structures Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 10, 2018 | Pubmed ID: 29992736 A New Concentration Jump Strategy Reveals the Lifetime of I-Motif at Physiological PH Without Force Analytical Chemistry. 03, 2018 | Pubmed ID: 29400441 Single-Molecule Mechanochemical PH Sensing Revealing the Proximity Effect of Hydroniums Generated by an Alkaline Phosphatase Analytical Chemistry. 02, 2018 | Pubmed ID: 29285923 Quantification of Chemical and Mechanical Effects on the Formation of the G-Quadruplex and I-Motif in Duplex DNA Biochemistry. 09, 2017 | Pubmed ID: 28738141 Adaptive and Specific Recognition of Telomeric G-Quadruplexes Via Polyvalency Induced Unstacking of Binding Units Journal of the American Chemical Society. 06, 2017 | Pubmed ID: 28505453 Confined Space Facilitates G-quadruplex Formation Nature Nanotechnology. 07, 2017 | Pubmed ID: 28346457 A Mechanosensor Mechanism Controls the G-Quadruplex/i-Motif Molecular Switch in the MYC Promoter NHE III Journal of the American Chemical Society. Oct, 2016 | Pubmed ID: 27669098 A Pharmacological Chaperone Molecule Induces Cancer Cell Death by Restoring Tertiary DNA Structures in Mutant HTERT Promoters Journal of the American Chemical Society. Oct, 2016 | Pubmed ID: 27643954 Mechanochemical Sensing of Single and Few Hg(II) Ions Using Polyvalent Principles Analytical Chemistry. 10, 2016 | Pubmed ID: 27618437 Mechanical Properties of DNA Origami Nanoassemblies Are Determined by Holliday Junction Mechanophores Nucleic Acids Research. 08, 2016 | Pubmed ID: 27387283 Mutually Exclusive Formation of G-Quadruplex and I-Motif Is a General Phenomenon Governed by Steric Hindrance in Duplex DNA Biochemistry. Apr, 2016 | Pubmed ID: 27027664 Exploded View of Higher Order G-quadruplex Structures Through Click-chemistry Assisted Single-molecule Mechanical Unfolding Nucleic Acids Research. Jan, 2016 | Pubmed ID: 26626151 Dual Binding of an Antibody and a Small Molecule Increases the Stability of TERRA G-Quadruplex Angewandte Chemie (Weinheim an Der Bergstrasse, Germany). Jan, 2015 | Pubmed ID: 26300569 A Molecular Tuning Fork in Single-molecule Mechanochemical Sensing Angewandte Chemie (International Ed. in English). Jun, 2015 | Pubmed ID: 25960021 Mechanochemical Sensing: A Biomimetic Sensing Strategy Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. Jun, 2015 | Pubmed ID: 25916512 Divalent Cations and Molecular Crowding Buffers Stabilize G-triplex at Physiologically Relevant Temperatures Scientific Reports. Mar, 2015 | Pubmed ID: 25787838 Dissecting Cooperative Communications in a Protein with a High-throughput Single-molecule Scalpel Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. Jan, 2015 | Pubmed ID: 25470139 Dual Binding of an Antibody and a Small Molecule Increases the Stability of TERRA G-quadruplex Angewandte Chemie (International Ed. in English). Jan, 2015 | Pubmed ID: 25421962 Interaction of G-quadruplexes in the Full-length 3' Human Telomeric Overhang Journal of the American Chemical Society. Dec, 2014 | Pubmed ID: 25438191 Direct Quantification of Loop Interaction and π-π Stacking for G-quadruplex Stability at the Submolecular Level Journal of the American Chemical Society. Nov, 2014 | Pubmed ID: 25296000 Quantification of Topological Coupling Between DNA Superhelicity and G-quadruplex Formation Journal of the American Chemical Society. Oct, 2014 | Pubmed ID: 25216033 Intermediates Stabilized by Tryptophan Pairs Exist in Trpzip Beta-hairpins Biochemistry. Sep, 2014 | Pubmed ID: 25164564 Single-molecule Mechanochemical Sensing Using DNA Origami Nanostructures Angewandte Chemie (International Ed. in English). Jul, 2014 | Pubmed ID: 24931175 Nascent RNA Transcripts Facilitate the Formation of G-quadruplexes Nucleic Acids Research. Jun, 2014 | Pubmed ID: 24829453 Molecular Population Dynamics of DNA Structures in a Bcl-2 Promoter Sequence is Regulated by Small Molecules and the Transcription Factor HnRNP LL Nucleic Acids Research. May, 2014 | Pubmed ID: 24609386 Yoctoliter Thermometry for Single-molecule Investigations: a Generic Bead-on-a-tip Temperature-control Module Angewandte Chemie (International Ed. in English). Mar, 2014 | Pubmed ID: 24596309 Controlled Particle Collision Leads to Direct Observation of Docking and Fusion of Lipid Droplets in an Optical Trap Langmuir : the ACS Journal of Surfaces and Colloids. Feb, 2014 | Pubmed ID: 24447288 Mechanochemical Properties of Individual Human Telomeric RNA (TERRA) G-quadruplexes Chembiochem : a European Journal of Chemical Biology. Oct, 2013 | Pubmed ID: 24038851 Structural and Mechanical Properties of Individual Human Telomeric G-quadruplexes in Molecularly Crowded Solutions Nucleic Acids Research. Apr, 2013 | Pubmed ID: 23396442 Non-B DNA Structures Show Diverse Conformations and Complex Transition Kinetics Comparable to RNA or Proteins--a Perspective from Mechanical Unfolding and Refolding Experiments Chemical Record (New York, N.Y.). Feb, 2013 | Pubmed ID: 23389854 Long-Loop G-Quadruplexes Are Misfolded Population Minorities with Fast Transition Kinetics in Human Telomeric Sequences Journal of the American Chemical Society. Jan, 2013 | Pubmed ID: 23327686 Click Chemistry Assisted Single-molecule Fingerprinting Reveals a 3D Biomolecular Folding Funnel Journal of the American Chemical Society. Aug, 2012 | Pubmed ID: 22799529 Intramolecular Folding in Human ILPR Fragment with Three C-rich Repeats PloS One. 2012 | Pubmed ID: 22761750 G-quadruplex and I-motif Are Mutually Exclusive in ILPR Double-stranded DNA Biophysical Journal. Jun, 2012 | Pubmed ID: 22713573 Single-molecule Measurements of the Binding Between Small Molecules and DNA Aptamers Analytical Chemistry. Jun, 2012 | Pubmed ID: 22702719 Tertiary DNA Structure in the Single-Stranded HTERT Promoter Fragment Unfolds and Refolds by Parallel Pathways Via Cooperative or Sequential Events Journal of the American Chemical Society. Mar, 2012 | Pubmed ID: 22372563 Intramolecular Folding in Three Tandem Guanine Repeats of Human Telomeric DNA Chemical Communications (Cambridge, England). Feb, 2012 | Pubmed ID: 22234724 A Single-molecule Platform for Investigation of Interactions Between G-quadruplexes and Small-molecule Ligands Nature Chemistry. Aug, 2011 | Pubmed ID: 21941250 Detection of Single Nucleotide Polymorphism Using Tension-dependent Stochastic Behavior of a Single-molecule Template Journal of the American Chemical Society. Jul, 2011 | Pubmed ID: 21639132 Coexistence of an ILPR I-motif and a Partially Folded Structure with Comparable Mechanical Stability Revealed at the Single-molecule Level Journal of the American Chemical Society. Jul, 2010 | Pubmed ID: 20545340 ILPR Repeats Adopt Diverse G-quadruplex Conformations That Determine Insulin Binding Biopolymers. Jan, 2010 | Pubmed ID: 19688813 Direct Experimental Evidence for Quadruplex-quadruplex Interaction Within the Human ILPR Nucleic Acids Research. Jun, 2009 | Pubmed ID: 19324891 ILPR G-quadruplexes Formed in Seconds Demonstrate High Mechanical Stabilities Journal of the American Chemical Society. Feb, 2009 | Pubmed ID: 19154151 Ensemble Force Spectroscopy by Shear Forces Pravin Pokhrel1, Changpeng Hu1, Hanbin Mao1 1Department of Chemistry & Biochemistry, Kent State University JoVE 63741 Bioengineering
Ensemble Force Spectroscopy by Shear Forces Pravin Pokhrel1, Changpeng Hu1, Hanbin Mao1 1Department of Chemistry & Biochemistry, Kent State University JoVE 63741 Bioengineering
