Hassan Y. Naim Department of Physiological Chemistry University of Veterinary Medicine Hannover Biography Publications Institution JoVE Articles Hassan Y. Naim has not added a biography. If you are Hassan Y. Naim and would like to personalize this page please email our Author Liaison for assistance. Publications Antimicrobial Activity of HL-60 Cells Compared to Primary Blood-derived Neutrophils Against Staphylococcus Aureus Journal of Negative Results in Biomedicine. Feb, 2017 | Pubmed ID: 28214466 Molecular Pathogenicity of Novel Sucrase-isomaltase Mutations Found in Congenital Sucrase-isomaltase Deficiency Patients Biochimica Et Biophysica Acta. Mar, 2017 | Pubmed ID: 28062276 Structural Determinants for Transport of Lactase Phlorizin-hydrolase in the Early Secretory Pathway As a Multi-domain Membrane Glycoprotein Biochimica Et Biophysica Acta. Jan, 2017 | Pubmed ID: 27773655 Effects of SecDF on the Antimicrobial Functions of Cathelicidins Against Staphylococcus Aureus Veterinary Microbiology. Feb, 2017 | Pubmed ID: 27062479 Formation of Neutrophil Extracellular Traps Under Low Oxygen Level Frontiers in Immunology. 2016 | Pubmed ID: 27933059 Functional Variants in the Sucrase-isomaltase Gene Associate with Increased Risk of Irritable Bowel Syndrome Gut. Nov, 2016 | Pubmed ID: 27872184 Prostate-specific Membrane Antigen (PSMA) Assembles a Macromolecular Complex Regulating Growth and Survival of Prostate Cancer Cells "in Vitro" and Correlating with Progression "in Vivo" Oncotarget. Nov, 2016 | Pubmed ID: 27713116 Alterations in Membrane Trafficking and Pathophysiological Implications in Lysosomal Storage Disorders Biochimie. Nov, 2016 | Pubmed ID: 27664461 Guarea Kunthiana Bark Extract Enhances the Antimicrobial Activities of Human and Bovine Neutrophils Natural Product Communications. Jun, 2016 | Pubmed ID: 27534112 Molecular Biology of the Gut Molecular and Cellular Pediatrics. Dec, 2016 | Pubmed ID: 27518572 Cross-talk Between Intestinal Epithelial Cells and Immune Cells in Inflammatory Bowel Disease Scientific Reports. Jul, 2016 | Pubmed ID: 27417573 Intercellular Transfer of P-glycoprotein in Human Blood-brain Barrier Endothelial Cells is Increased by Histone Deacetylase Inhibitors Scientific Reports. Jul, 2016 | Pubmed ID: 27375084 Iron-chelating Agent Desferrioxamine Stimulates Formation of Neutrophil Extracellular Traps (NETs) in Human Blood-derived Neutrophils Bioscience Reports. Jul, 2016 | Pubmed ID: 27129288 The Impact of Hypoxia on Intestinal Epithelial Cell Functions: Consequences for Invasion by Bacterial Pathogens Molecular and Cellular Pediatrics. Dec, 2016 | Pubmed ID: 27002817 Endocytosis in Enterocytes Wiener Medizinische Wochenschrift (1946). May, 2016 | Pubmed ID: 26993488 The Multiple Roles of Sucrase-isomaltase in the Intestinal Physiology Molecular and Cellular Pediatrics. Dec, 2016 | Pubmed ID: 26812950 What to Do with High Autofluorescence Background in Pancreatic Tissues - an Efficient Sudan Black B Quenching Method for Specific Immunofluorescence Labelling Histopathology. Sep, 2016 | Pubmed ID: 26802460 Hypoxia Decreases Invasin-Mediated Yersinia Enterocolitica Internalization into Caco-2 Cells PloS One. 2016 | Pubmed ID: 26731748 In Vitro Activity of Human and Animal Cathelicidins Against Livestock-associated Methicillin-resistant Staphylococcus Aureus Veterinary Microbiology. Oct, 2016 | Pubmed ID: 26453316 The Pathobiochemistry of Gastrointestinal Symptoms in a Patient with Niemann-Pick Type C Disease JIMD Reports. 2016 | Pubmed ID: 26122626 Central Nervous System Demyelination and Remyelination is Independent from Systemic Cholesterol Level in Theiler's Murine Encephalomyelitis Brain Pathology (Zurich, Switzerland). Jan, 2016 | Pubmed ID: 25959295 Measuring Oxygen Levels in Caco-2 Cultures Hypoxia (Auckland, N.Z.). 2015 | Pubmed ID: 27774482 A Novel SLC27A4 Splice Acceptor Site Mutation in Great Danes with Ichthyosis PloS One. 2015 | Pubmed ID: 26506231 Yersinia Enterocolitica-mediated Degradation of Neutrophil Extracellular Traps (NETs) FEMS Microbiology Letters. Dec, 2015 | Pubmed ID: 26459885 The Diverse Forms of Lactose Intolerance and the Putative Linkage to Several Cancers Nutrients. Aug, 2015 | Pubmed ID: 26343715 Cholesterol-rich Lipid Rafts Play an Important Role in the Cyprinid Herpesvirus 3 Replication Cycle Veterinary Microbiology. Sep, 2015 | Pubmed ID: 26059657 Congenital Lactose Intolerance is Triggered by Severe Mutations on Both Alleles of the Lactase Gene BMC Gastroenterology. Mar, 2015 | Pubmed ID: 25881162 Identification of a Novel DNase of Streptococcus Suis (EndAsuis) Important for Neutrophil Extracellular Trap Degradation During Exponential Growth Microbiology (Reading, England). Apr, 2015 | Pubmed ID: 25667008 Precision-cut Intestinal Slices As a Culture System to Analyze the Infection of Differentiated Intestinal Epithelial Cells by Avian Influenza Viruses Journal of Virological Methods. Feb, 2015 | Pubmed ID: 25445801 Genetic Reporter Analysis Reveals an Expandable Reservoir of OCT4+ Cells in Adult Skin Cell Regeneration (London, England). 2014 | Pubmed ID: 25408888 The Antimicrobial Peptide LL-37 Facilitates the Formation of Neutrophil Extracellular Traps The Biochemical Journal. Nov, 2014 | Pubmed ID: 25181554 Lipid Alterations in Human Blood-derived Neutrophils Lead to Formation of Neutrophil Extracellular Traps European Journal of Cell Biology. Aug-Sep, 2014 | Pubmed ID: 25172775 Canine Epidermal Lipid Sampling by Skin Scrub Revealed Variations Between Different Body Sites and Normal and Atopic Dogs BMC Veterinary Research. Jul, 2014 | Pubmed ID: 25012966 Novel Role of the Antimicrobial Peptide LL-37 in the Protection of Neutrophil Extracellular Traps Against Degradation by Bacterial Nucleases Journal of Innate Immunity. 2014 | Pubmed ID: 25012862 Long Term Differential Consequences of Miglustat Therapy on Intestinal Disaccharidases Journal of Inherited Metabolic Disease. Nov, 2014 | Pubmed ID: 24863482 Lidocaine Effect on Flotillin-2 Distribution in Detergent-resistant Membranes of Equine Jejunal Smooth Muscle in Vitro Veterinary Journal (London, England : 1997). May, 2014 | Pubmed ID: 24680669 Enrofloxacin Enhances the Formation of Neutrophil Extracellular Traps in Bovine Granulocytes Journal of Innate Immunity. 2014 | Pubmed ID: 24642685 Drug-induced Trafficking of P-glycoprotein in Human Brain Capillary Endothelial Cells As Demonstrated by Exposure to Mitomycin C PloS One. 2014 | Pubmed ID: 24505408 The Effect of β-glucan on Formation and Functionality of Neutrophil Extracellular Traps in Carp (Cyprinus Carpio L.) Developmental and Comparative Immunology. Jun, 2014 | Pubmed ID: 24434196 Isolation and Analysis of Membrane Lipids and Lipid Rafts in Common Carp (Cyprinus Carpio L.) Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. Mar, 2014 | Pubmed ID: 24326265 Discriminatory Role of Detergent-Resistant Membranes in the Dimerization and Endocytosis of Prostate-Specific Membrane Antigen PloS One. 2013 | Pubmed ID: 23840421 Cloning and Characterization of Canine Prostate-specific Membrane Antigen The Prostate. May, 2013 | Pubmed ID: 23359458 Retinal Glycoprotein Enrichment by Concanavalin a Enabled Identification of Novel Membrane Autoantigen Synaptotagmin-1 in Equine Recurrent Uveitis PloS One. 2012 | Pubmed ID: 23236410 Transient Sucrose and Starch Intolerance Journal of Pediatric Gastroenterology and Nutrition. Nov, 2012 | Pubmed ID: 23103653 Congenital Sucrase-isomaltase Deficiency: Summary of an Evaluation in One Family Journal of Pediatric Gastroenterology and Nutrition. Nov, 2012 | Pubmed ID: 23103651 Investigations of the Structures and Inhibitory Properties of Intestinal Maltase Glucoamylase and Sucrase Isomaltase Journal of Pediatric Gastroenterology and Nutrition. Nov, 2012 | Pubmed ID: 23103645 Congenital Sucrase-isomaltase Deficiency: Heterogeneity of Inheritance, Trafficking, and Function of an Intestinal Enzyme Complex Journal of Pediatric Gastroenterology and Nutrition. Nov, 2012 | Pubmed ID: 23103643 Research Progress Reported at the 50th Anniversary of the Discovery of Congenital Sucrase-Isomaltase Deficiency Workshop Journal of Pediatric Gastroenterology and Nutrition. Nov, 2012 | Pubmed ID: 23103641 Starch Source Influences Dietary Glucose Generation at the Mucosal α-glucosidase Level The Journal of Biological Chemistry. Oct, 2012 | Pubmed ID: 22988246 Miglustat-induced Intestinal Carbohydrate Malabsorption is Due to the Inhibition of α-glucosidases, but Not β-galactosidases Journal of Inherited Metabolic Disease. Nov, 2012 | Pubmed ID: 22976762 β-Glucan Protects Neutrophil Extracellular Traps Against Degradation by Aeromonas Hydrophila in Carp (Cyprinus Carpio) Fish & Shellfish Immunology. Oct, 2012 | Pubmed ID: 22959188 A Novel Role for the Transcription Factor HIF-1α in the Formation of Mast Cell Extracellular Traps The Biochemical Journal. Aug, 2012 | Pubmed ID: 22738198 Cadherin-related Protein 24 Induces Morphological Changes and Partial Cell Polarization by Facilitating Direct Cell-cell Interactions Biological Chemistry. May, 2012 | Pubmed ID: 22628312 Unexpected High Digestion Rate of Cooked Starch by the Ct-maltase-glucoamylase Small Intestine Mucosal α-glucosidase Subunit PloS One. 2012 | Pubmed ID: 22563462 Demonstration of Free Fatty Acids in the Integument of Semi-aquatic and Aquatic Mammals Acta Histochemica. Feb, 2012 | Pubmed ID: 21524787 Mapping the Intestinal Alpha-glucogenic Enzyme Specificities of Starch Digesting Maltase-glucoamylase and Sucrase-isomaltase Bioorganic & Medicinal Chemistry. Jul, 2011 | Pubmed ID: 21669536 Impairment of Protein Trafficking by Direct Interaction of Gliadin Peptides with Actin Experimental Cell Research. Sep, 2011 | Pubmed ID: 21663741 The Dual Role of Annexin II in Targeting of Brush Border Proteins and in Intestinal Cell Polarity Differentiation; Research in Biological Diversity. Apr, 2011 | Pubmed ID: 21330046 TGFα-associated MUC2 and MUC3 Expression of the Gastric Epithelium in Menetrier's Disease During Remission of Ulcerative Colitis Gut. Nov, 2011 | Pubmed ID: 21303913 A Modified Lipid Composition in Fabry Disease Leads to an Intracellular Block of the Detergent-resistant Membrane-associated Dipeptidyl Peptidase IV Journal of Inherited Metabolic Disease. Aug, 2010 | Pubmed ID: 20495958 Structural Basis for Substrate Selectivity in Human Maltase-glucoamylase and Sucrase-isomaltase N-terminal Domains The Journal of Biological Chemistry. Jun, 2010 | Pubmed ID: 20356844 Protocadherin of the Liver, Kidney, and Colon Associates with Detergent-resistant Membranes During Cellular Differentiation The Journal of Biological Chemistry. Apr, 2010 | Pubmed ID: 20159971 Structural Hierarchy of Regulatory Elements in the Folding and Transport of an Intestinal Multidomain Protein The Journal of Biological Chemistry. Feb, 2010 | Pubmed ID: 19955176 Endocytotic Segregation of Gliadin Peptide 31-49 in Enterocytes Gut. Mar, 2010 | Pubmed ID: 19654123 Congenital and Putatively Acquired Forms of Sucrase-isomaltase Deficiency in Infancy: Effects of Sacrosidase Therapy Journal of Pediatric Gastroenterology and Nutrition. Oct, 2009 | Pubmed ID: 19680155 Glycoprotein Analysis of Porcine Bronchoalveolar Lavage Fluid Reveals Potential Biomarkers Corresponding to Resistance to Actinobacillus Pleuropneumoniae Infection Veterinary Research. Nov-Dec, 2009 | Pubmed ID: 19638268 Domains in Biological Membranes Experimental Cell Research. Oct, 2009 | Pubmed ID: 19632223 Toxic Peptides in Frazer's Fraction Interact with the Actin Cytoskeleton and Affect the Targeting and Function of Intestinal Proteins Experimental Cell Research. Nov, 2009 | Pubmed ID: 19576210 Impact of Glycosylation and Detergent-resistant Membranes on the Function of Intestinal Sucrase-isomaltase Biological Chemistry. Jul, 2009 | Pubmed ID: 19426137 The Prostate Specific Membrane Antigen Regulates the Expression of IL-6 and CCL5 in Prostate Tumour Cells by Activating the MAPK Pathways PloS One. 2009 | Pubmed ID: 19242540 Impaired Trafficking and Subcellular Localization of a Mutant Lactase Associated with Congenital Lactase Deficiency Gastroenterology. Jun, 2009 | Pubmed ID: 19208354 Compound Heterozygous Mutations Affect Protein Folding and Function in Patients with Congenital Sucrase-isomaltase Deficiency Gastroenterology. Mar, 2009 | Pubmed ID: 19121318 The Influence of Linoleic and Linolenic Acid on the Activity and Intracellular Localisation of Phospholipase D in COS-1 Cells Biological Chemistry. Mar, 2009 | Pubmed ID: 19090716 Association of a GPI-anchored Protein with Detergent-resistant Membranes Facilitates Its Trafficking Through the Early Secretory Pathway Experimental Cell Research. Jan, 2009 | Pubmed ID: 19022244 Importance of Cholesterol-rich Membrane Microdomains in the Interaction of the S Protein of SARS-coronavirus with the Cellular Receptor Angiotensin-converting Enzyme 2 Virology. Nov, 2008 | Pubmed ID: 18814896 Ex Vivo Expanded Hematopoietic Progenitor Cells Improve Cardiac Function After Myocardial Infarction: Role of Beta-catenin Transduction and Cell Dose Journal of Molecular and Cellular Cardiology. Sep, 2008 | Pubmed ID: 18671980 Mosaic Pattern of Sucrase Isomaltase Deficiency in Two Brothers Pediatric Research. Jan, 2008 | Pubmed ID: 18043509 Different Glycoforms of Prostate-specific Membrane Antigen Are Intracellularly Transported Through Their Association with Distinct Detergent-resistant Membranes The Biochemical Journal. Jan, 2008 | Pubmed ID: 17935484 A Genetically Engineered Prime-boost Vaccination Strategy for Oculonasal Delivery with Poly(D,L-lactic-co-glycolic Acid) Microparticles Against Infection of Turkeys with Avian Metapneumovirus Vaccine. Nov, 2007 | Pubmed ID: 17920166 Neuropeptide Y (NPY) Cleaving Enzymes: Structural and Functional Homologues of Dipeptidyl Peptidase 4 Peptides. Feb, 2007 | Pubmed ID: 17223229 Both Cleavage Products of the MCLCA3 Protein Are Secreted Soluble Proteins The Journal of Biological Chemistry. Oct, 2006 | Pubmed ID: 16895902 Transcoronary Delivery of Bone Marrow Cells to the Infarcted Murine Myocardium: Feasibility, Cellular Kinetics, and Improvement in Cardiac Function Basic Research in Cardiology. Jul, 2006 | Pubmed ID: 16705471 Analysis of ACE2 in Polarized Epithelial Cells: Surface Expression and Function As Receptor for Severe Acute Respiratory Syndrome-associated Coronavirus The Journal of General Virology. Jun, 2006 | Pubmed ID: 16690935 Altered Folding, Turnover, and Polarized Sorting Act in Concert to Define a Novel Pathomechanism of Congenital Sucrase-isomaltase Deficiency The Journal of Biological Chemistry. May, 2006 | Pubmed ID: 16543230 Ex Vivo Biochemical Analysis of CFTR in Human Rectal Biopsies Biochimica Et Biophysica Acta. Apr, 2006 | Pubmed ID: 16504487 Requirement for Galectin-3 in Apical Protein Sorting Current Biology : CB. Feb, 2006 | Pubmed ID: 16488876 A Mutation in Aminopeptidase N (CD13) Isolated from a Patient Suffering from Leukemia Leads to an Arrest in the Endoplasmic Reticulum The Journal of Biological Chemistry. Apr, 2006 | Pubmed ID: 16469741 Novel Mutations in the Human Sucrase-isomaltase Gene (SI) That Cause Congenital Carbohydrate Malabsorption Human Mutation. Jan, 2006 | Pubmed ID: 16329100 Apical Transport and Folding of Prostate-specific Membrane Antigen Occurs Independent of Glycan Processing The Journal of Biological Chemistry. Feb, 2006 | Pubmed ID: 16221666 A Novel Type of Detergent-resistant Membranes May Contribute to an Early Protein Sorting Event in Epithelial Cells The Journal of Biological Chemistry. Dec, 2005 | Pubmed ID: 16230359 Impaired Trafficking of Mutants of Lysosomal Glucocerebrosidase in Gaucher's Disease The International Journal of Biochemistry & Cell Biology. Nov, 2005 | Pubmed ID: 15982918 A Phenylalanine-based Folding Determinant in Intestinal Sucrase-isomaltase That Functions in the Context of a Quality Control Mechanism Beyond the Endoplasmic Reticulum Journal of Cell Science. Jun, 2005 | Pubmed ID: 15944403 Alpha-kinase 1, a New Component in Apical Protein Transport The Journal of Biological Chemistry. Jul, 2005 | Pubmed ID: 15883161 Trafficking Pathways of Cx49-GFP in Living Mammalian Cells Biological Chemistry. Feb, 2005 | Pubmed ID: 15843159 Binding of Par-4 to the Actin Cytoskeleton is Essential for Par-4/Dlk-mediated Apoptosis Experimental Cell Research. May, 2005 | Pubmed ID: 15817164 A Novel Sorting Signal for Intracellular Localization is Present in the S Protein of a Porcine Coronavirus but Absent from Severe Acute Respiratory Syndrome-associated Coronavirus The Journal of Biological Chemistry. Oct, 2004 | Pubmed ID: 15304515 Antigen Transport and Cytoskeletal Characteristics of a Distinct Enterocyte Population in Inflammatory Bowel Diseases The American Journal of Pathology. Aug, 2004 | Pubmed ID: 15277217 Annexin II is Required for Apical Transport in Polarized Epithelial Cells The Journal of Biological Chemistry. Jan, 2004 | Pubmed ID: 14670963 Congenital Sucrase-isomaltase Deficiency Because of an Accumulation of the Mutant Enzyme in the Endoplasmic Reticulum Gastroenterology. Dec, 2003 | Pubmed ID: 14724820 Distinct Cytoskeletal Tracks Direct Individual Vesicle Populations to the Apical Membrane of Epithelial Cells Current Biology : CB. Apr, 2003 | Pubmed ID: 12676094 A Glutamine to Proline Exchange at Amino Acid Residue 1098 in Sucrase Causes a Temperature-sensitive Arrest of Sucrase-isomaltase in the Endoplasmic Reticulum and Cis-Golgi The Journal of Biological Chemistry. May, 2003 | Pubmed ID: 12624106 Deglycosylation by Small Intestinal Epithelial Cell Beta-glucosidases is a Critical Step in the Absorption and Metabolism of Dietary Flavonoid Glycosides in Humans European Journal of Nutrition. Jan, 2003 | Pubmed ID: 12594539 Cloning and Characterization of the Mammalian-specific Nicolin 1 Gene (NICN1) Encoding a Nuclear 24 KDa Protein European Journal of Biochemistry. Nov, 2002 | Pubmed ID: 12392556 Sucrase is an Intramolecular Chaperone Located at the C-terminal End of the Sucrase-isomaltase Enzyme Complex The Journal of Biological Chemistry. Aug, 2002 | Pubmed ID: 12055199 Intestinal Dipeptidyl Peptidase IV is Efficiently Sorted to the Apical Membrane Through the Concerted Action of N- and O-glycans As Well As Association with Lipid Microdomains The Journal of Biological Chemistry. Mar, 2002 | Pubmed ID: 11773049 The Prosequence of Human Lactase-phlorizin Hydrolase Modulates the Folding of the Mature Enzyme The Journal of Biological Chemistry. Mar, 2002 | Pubmed ID: 11751874 Metoder för att studera Lipidförändringarna i neutrofiler och efterföljande bildning av neutrofila Extracellulär Fällor Graham Brogden*1,2, Ariane Neumann*1,3, Diab M. Husein1, Friederike Reuner1,4, Hassan Y. Naim1, Maren von Köckritz-Blickwede1,4 1Department of Physiological Chemistry, University of Veterinary Medicine Hannover, 2Fish Disease Research Unit, University of Veterinary Medicine, 3Department of Clinical Sciences, Biomedical Center, Lund University, 4Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine Hannover JoVE 54667 Immunology and Infection
Metoder för att studera Lipidförändringarna i neutrofiler och efterföljande bildning av neutrofila Extracellulär Fällor Graham Brogden*1,2, Ariane Neumann*1,3, Diab M. Husein1, Friederike Reuner1,4, Hassan Y. Naim1, Maren von Köckritz-Blickwede1,4 1Department of Physiological Chemistry, University of Veterinary Medicine Hannover, 2Fish Disease Research Unit, University of Veterinary Medicine, 3Department of Clinical Sciences, Biomedical Center, Lund University, 4Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine Hannover JoVE 54667 Immunology and Infection
