Herman H.W. Silljé Department of Cardiology, University Medical Center Groningen University of Groningen Biography Publications Institution JoVE Articles Herman H.W. Silljé has not added a biography. If you are Herman H.W. Silljé and would like to personalize this page please email our Author Liaison for assistance. Publications Effects of Sodium-Glucose Co-transporter 2 Inhibition with Empaglifozin on Renal Structure and Function in Non-diabetic Rats with Left Ventricular Dysfunction After Myocardial Infarction Cardiovascular Drugs and Therapy. Mar, 2020 | Pubmed ID: 32185580 Sodium-glucose Co-transporter 2 Inhibition As a Mitochondrial Therapy for Atrial Fibrillation in Patients with Diabetes? Cardiovascular Diabetology. Jan, 2020 | Pubmed ID: 31910841 Pharmacological Myeloperoxidase (MPO) Inhibition in an Obese/hypertensive Mouse Model Attenuates Obesity and Liver Damage, but Not Cardiac Remodeling Scientific Reports. Dec, 2019 | Pubmed ID: 31822739 Metabolic Remodeling in the Pressure-Loaded Right Ventricle: Shifts in Glucose and Fatty Acid Metabolism-A Systematic Review and Meta-Analysis Journal of the American Heart Association. 11, 2019 | Pubmed ID: 31657265 Current Understanding of Fibrosis in Genetic Cardiomyopathies Trends in Cardiovascular Medicine. Sep, 2019 | Pubmed ID: 31585768 Sodium-glucose Co-transporter 2 Inhibition with Empagliflozin Improves Cardiac Function in Non-diabetic Rats with Left Ventricular Dysfunction After Myocardial Infarction European Journal of Heart Failure. 07, 2019 | Pubmed ID: 31033127 A Novel Method Optimizing the Normalization of Cardiac Parameters in Small Animal Models: the Importance of Dimensional Indexing American Journal of Physiology. Heart and Circulatory Physiology. 06, 2019 | Pubmed ID: 30978120 The Vicious Cycle of Arrhythmia and Myocardial Fibrosis European Journal of Heart Failure. 04, 2019 | Pubmed ID: 30698320 Plasma Levels of Heart Failure Biomarkers Are Primarily a Reflection of Extracardiac Production Theranostics. 2018 | Pubmed ID: 30128044 OPLAH Ablation Leads to Accumulation of 5-oxoproline, Oxidative Stress, Fibrosis, and Elevated Fillings Pressures: a Murine Model for Heart Failure with a Preserved Ejection Fraction Cardiovascular Research. 12, 2018 | Pubmed ID: 30032247 Novel Heart Failure Biomarkers: Why Do We Fail to Exploit Their Potential? Critical Reviews in Clinical Laboratory Sciences. 06, 2018 | Pubmed ID: 29663841 Heart Failure Stimulates Tumor Growth by Circulating Factors Circulation. 08, 2018 | Pubmed ID: 29459363 Galectin-3 Activation and Inhibition in Heart Failure and Cardiovascular Disease: An Update Theranostics. 2018 | Pubmed ID: 29344292 Mutations in Causing a Novel Orthostatic Hypotension Syndrome Circulation Research. 03, 2018 | Pubmed ID: 29343526 Volume Load-induced Right Ventricular Dysfunction in Animal Models: Insights in a Translational Gap in Congenital Heart Disease European Journal of Heart Failure. 04, 2018 | Pubmed ID: 28925007 Accumulation of 5-oxoproline in Myocardial Dysfunction and the Protective Effects of OPLAH Science Translational Medicine. Nov, 2017 | Pubmed ID: 29118264 From Inflammation to Fibrosis-Molecular and Cellular Mechanisms of Myocardial Tissue Remodelling and Perspectives on Differential Treatment Opportunities Current Heart Failure Reports. 08, 2017 | Pubmed ID: 28707261 Heart Failure: Macrophages Take Centre Stage in the Heart-brain-kidney Axis Nature Reviews. Nephrology. 07, 2017 | Pubmed ID: 28555651 Rodent Heart Failure Models Do Not Reflect the Human Circulating MicroRNA Signature in Heart Failure PloS One. 2017 | Pubmed ID: 28475616 HE4 Serum Levels Are Associated with Heart Failure Severity in Patients With Chronic Heart Failure Journal of Cardiac Failure. Jan, 2017 | Pubmed ID: 27224553 Inhibition of Interleukin-6 Receptor in a Murine Model of Myocardial Ischemia-Reperfusion PloS One. 2016 | Pubmed ID: 27936014 52 Genetic Loci Influencing Myocardial Mass Journal of the American College of Cardiology. Sep, 2016 | Pubmed ID: 27659466 In EXOG-depleted Cardiomyocytes Cell Death is Marked by a Decreased Mitochondrial Reserve Capacity of the Electron Transport Chain BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. 07, 2016 | Pubmed ID: 27417117 Overexpression of A Kinase Interacting Protein 1 Attenuates Myocardial Ischaemia/reperfusion Injury but Does Not Influence Heart Failure Development Cardiovascular Research. 08, 2016 | Pubmed ID: 27302402 HIPPO-Integrin-linked Kinase Cross-Talk Controls Self-Sustaining Proliferation and Survival in Pulmonary Hypertension American Journal of Respiratory and Critical Care Medicine. Oct, 2016 | Pubmed ID: 27119551 Hypertrophy Induced KIF5B Controls Mitochondrial Localization and Function in Neonatal Rat Cardiomyocytes Journal of Molecular and Cellular Cardiology. 08, 2016 | Pubmed ID: 27094714 The Fibrosis-cell Death Axis in Heart Failure Heart Failure Reviews. Mar, 2016 | Pubmed ID: 26883434 LXRα Improves Myocardial Glucose Tolerance and Reduces Cardiac Hypertrophy in a Mouse Model of Obesity-induced Type 2 Diabetes Diabetologia. Mar, 2016 | Pubmed ID: 26684450 Cardiac LXRα Protects Against Pathological Cardiac Hypertrophy and Dysfunction by Enhancing Glucose Uptake and Utilization EMBO Molecular Medicine. Sep, 2015 | Pubmed ID: 26160456 The Liver X Receptor Agonist AZ876 Protects Against Pathological Cardiac Hypertrophy and Fibrosis Without Lipogenic Side Effects European Journal of Heart Failure. Mar, 2015 | Pubmed ID: 25684370 Clinical Symptoms of Right Ventricular Failure in Experimental Chronic Pressure Load Are Associated with Progressive Diastolic Dysfunction Journal of Molecular and Cellular Cardiology. Feb, 2015 | Pubmed ID: 25486580 Loss of Mitochondrial Exo/endonuclease EXOG Affects Mitochondrial Respiration and Induces ROS-mediated Cardiomyocyte Hypertrophy American Journal of Physiology. Cell Physiology. Jan, 2015 | Pubmed ID: 25377088 Cardiac Function and Architecture Are Maintained in a Model of Cardiorestricted Overexpression of the Prorenin-renin Receptor PloS One. 2014 | Pubmed ID: 24587131 The WAP Four-disulfide Core Domain Protein HE4: a Novel Biomarker for Heart Failure JACC. Heart Failure. Apr, 2013 | Pubmed ID: 24621840 AKIP1 Expression Modulates Mitochondrial Function in Rat Neonatal Cardiomyocytes PloS One. 2013 | Pubmed ID: 24236204 AKIP1, a Cardiac Hypertrophy Induced Protein That Stimulates Cardiomyocyte Growth Via the Akt Pathway International Journal of Molecular Sciences. Oct, 2013 | Pubmed ID: 24169435 SMIM1 Underlies the Vel Blood Group and Influences Red Blood Cell Traits Nature Genetics. May, 2013 | Pubmed ID: 23563608 Genome-wide Association Study on Plasma Levels of Midregional-proadrenomedullin and C-terminal-pro-endothelin-1 Hypertension (Dallas, Tex. : 1979). Mar, 2013 | Pubmed ID: 23381795 Suicidal Erythrocyte Death, Eryptosis, As a Novel Mechanism in Heart Failure-associated Anaemia Cardiovascular Research. Apr, 2013 | Pubmed ID: 23341574 Genetic and Pharmacological Inhibition of Galectin-3 Prevents Cardiac Remodeling by Interfering with Myocardial Fibrogenesis Circulation. Heart Failure. Jan, 2013 | Pubmed ID: 23230309 Seventy-five Genetic Loci Influencing the Human Red Blood Cell Nature. Dec, 2012 | Pubmed ID: 23222517 The Vitamin D Receptor Activator Paricalcitol Prevents Fibrosis and Diastolic Dysfunction in a Murine Model of Pressure Overload The Journal of Steroid Biochemistry and Molecular Biology. Nov, 2012 | Pubmed ID: 22800987 Sildenafil Enhances Systolic Adaptation, but Does Not Prevent Diastolic Dysfunction, in the Pressure-loaded Right Ventricle European Journal of Heart Failure. Sep, 2012 | Pubmed ID: 22730335 Identification of Hypertrophy- and Heart Failure-associated Genes by Combining in Vitro and in Vivo Models Physiological Genomics. Apr, 2012 | Pubmed ID: 22353257 DHRS7c, a Novel Cardiomyocyte-expressed Gene That is Down-regulated by Adrenergic Stimulation and in Heart Failure European Journal of Heart Failure. Jan, 2012 | Pubmed ID: 22143674 Regulation of the (pro)renin-renin Receptor in Cardiac Remodelling Journal of Cellular and Molecular Medicine. Apr, 2012 | Pubmed ID: 21722305 Early and Late Effects of the DPP-4 Inhibitor Vildagliptin in a Rat Model of Post-myocardial Infarction Heart Failure Cardiovascular Diabetology. Sep, 2011 | Pubmed ID: 21955567 Metformin Improves Cardiac Function in a Nondiabetic Rat Model of Post-MI Heart Failure American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2011 | Pubmed ID: 21572014 Vitamin D Status and Outcomes in Heart Failure Patients European Journal of Heart Failure. Jun, 2011 | Pubmed ID: 21543375 Heart Failure-associated Anemia: Bone Marrow Dysfunction and Response to Erythropoietin Journal of Molecular Medicine (Berlin, Germany). Apr, 2011 | Pubmed ID: 21191566 The Plk1 Inhibitor BI 2536 Temporarily Arrests Primary Cardiac Fibroblasts in Mitosis and Generates Aneuploidy in Vitro PloS One. Sep, 2010 | Pubmed ID: 20886032 Glucagon-like Peptide 1 Prevents Reactive Oxygen Species-induced Endothelial Cell Senescence Through the Activation of Protein Kinase A Arteriosclerosis, Thrombosis, and Vascular Biology. Jul, 2010 | Pubmed ID: 20448207 Quantification of Biventricular Function and Morphology by Cardiac Magnetic Resonance Imaging in Mice with Pulmonary Artery Banding Anne-Marie C. Koop*1, Quint A.J. Hagdorn*1, Kees (C.) W.A. van de Kolk2,3, Annemieke van Oosten2, Michel Weij2, Herman H.W. Silljé4, Tineke P. Willems5, Rolf M.F. Berger1 1Center for Congenital Heart Diseases, Department of Pediatric Cardiology, University Medical Center Groningen, University of Groningen, 2The Central Animal Facility, University Medical Center Groningen, University of Groningen, 3Gronsai (Groningen Small Animal Imaging Facility), University Medical Center Groningen, University of Groningen, 4Department of Cardiology, University Medical Center Groningen, University of Groningen, 5Department of Radiology, University Medical Center Groningen, University of Groningen JoVE 60837 Medicine
Quantification of Biventricular Function and Morphology by Cardiac Magnetic Resonance Imaging in Mice with Pulmonary Artery Banding Anne-Marie C. Koop*1, Quint A.J. Hagdorn*1, Kees (C.) W.A. van de Kolk2,3, Annemieke van Oosten2, Michel Weij2, Herman H.W. Silljé4, Tineke P. Willems5, Rolf M.F. Berger1 1Center for Congenital Heart Diseases, Department of Pediatric Cardiology, University Medical Center Groningen, University of Groningen, 2The Central Animal Facility, University Medical Center Groningen, University of Groningen, 3Gronsai (Groningen Small Animal Imaging Facility), University Medical Center Groningen, University of Groningen, 4Department of Cardiology, University Medical Center Groningen, University of Groningen, 5Department of Radiology, University Medical Center Groningen, University of Groningen JoVE 60837 Medicine