Hiroshi Kawamoto

Publications

• Evolutionary Reversion in Tumorigenesis
  Frontiers in Oncology. 2023  |   Pubmed ID: 38023242
• Regulation of Lymphoid-myeloid Lineage Bias Through Regnase-1/3-mediated Control of Nfkbiz
  Blood. Nov, 2023  |   Pubmed ID: 37922454
• SETBP1 is Dispensable for Normal and Malignant Hematopoiesis
  Leukemia. Sep, 2023  |   Pubmed ID: 37464069
• [Development of "Off the Shelf" T Cells for Cancer Immunotherapy]
  Gan to Kagaku Ryoho. Cancer & Chemotherapy. May, 2023  |   Pubmed ID: 37218312
• Characteristic Differences in the Abundance of Tumor-infiltrating Lymphocytes and Intratumoral Developing T Cells in Thymoma, with Special Reference to PD-1 Expression
  Cancer Immunology, Immunotherapy : CII. Aug, 2023  |   Pubmed ID: 37060363
• Murine Breast Cancers Disorganize the Liver Transcriptome in a Zonated Manner
  Communications Biology. Jan, 2023  |   Pubmed ID: 36694005
• Tracing the Evolutionary History of Blood Cells to the Unicellular Ancestor of Animals
  Blood. Dec, 2022  |   Pubmed ID: 36112959
• Aberrant EVI1 Splicing Contributes to EVI1-rearranged Leukemia
  Blood. Aug, 2022  |   Pubmed ID: 35709354
• Remote Solid Cancers Rewire Hepatic Nitrogen Metabolism Via Host Nicotinamide-N-methyltransferase
  Nature Communications. 06, 2022  |   Pubmed ID: 35705545
• Propionic Acid, Induced in Gut by an Inulin Diet, Suppresses Inflammation and Ameliorates Liver Ischemia and Reperfusion Injury in Mice
  Frontiers in Immunology. 2022  |   Pubmed ID: 35572528
• Increase in the Incidence of Acute Inflammatory Reactions to Injectable Fillers During COVID-19 Era
  Journal of Cosmetic Dermatology. May, 2022  |   Pubmed ID: 35218285
• Isolation of TCR Genes with Tumor-killing Activity from Tumor-infiltrating and Circulating Lymphocytes in a Tumor Rejection Cynomolgus Macaque Model
  Molecular Therapy Oncolytics. Mar, 2022  |   Pubmed ID: 35024435
• CD153/CD30 Signaling Promotes Age-dependent Tertiary Lymphoid Tissue Expansion and Kidney Injury
  The Journal of Clinical Investigation. Jan, 2022  |   Pubmed ID: 34813503
• Regeneration of Antigen-specific T Cells by Using Induced Pluripotent Stem Cell (iPSC) Technology
  International Immunology. Nov, 2021  |   Pubmed ID: 34661676
• [The Origin of Blood Cells and Myeloid Cells]
  [Rinsho Ketsueki] The Japanese Journal of Clinical Hematology. 2021  |   Pubmed ID: 34248129
• Possible NK Cell-mediated Immune Responses Against IPSC-derived Cells in Allogeneic Transplantation Settings
  Inflammation and Regeneration. Jan, 2021  |   Pubmed ID: 33407951
• A Regulatory Element in the 3'-untranslated Region of CEBPA is Associated with Myeloid/NK/T-cell Leukemia
  European Journal of Haematology. Mar, 2021  |   Pubmed ID: 33197296
• [Mass-Production of Cytotoxic T Lymphocytes Regenerated from Pluripotent Stem Cells-To Target Solid Tumors]
  Gan to Kagaku Ryoho. Cancer & Chemotherapy. Oct, 2020  |   Pubmed ID: 33130732
• Regeneration of Tumor-Antigen-Specific Cytotoxic T Lymphocytes from IPSCs Transduced with Exogenous TCR Genes
  Molecular Therapy. Methods & Clinical Development. Dec, 2020  |   Pubmed ID: 33102617
• Cytotoxic T Lymphocytes Regenerated from IPS Cells Have Therapeutic Efficacy in a Patient-Derived Xenograft Solid Tumor Model
  IScience. Apr, 2020  |   Pubmed ID: 32259478
• Long Non-coding RNA MANCR is a Target of BET Bromodomain Protein BRD4 and Plays a Critical Role in Cellular Migration and Invasion Abilities of Prostate Cancer
  Biochemical and Biophysical Research Communications. May, 2020  |   Pubmed ID: 32199616
• High Frequency Production of T Cell-Derived IPSC Clones Capable of Generating Potent Cytotoxic T Cells
  Molecular Therapy. Methods & Clinical Development. Mar, 2020  |   Pubmed ID: 31970197
• [Mass-Production of Tumor Antigen-Specific Cytotoxic T Lymphocytes Using the IPS Cell Technology-Development of "Off-the-Shelf T Cells"for the Use in Allogeneic Transfusion Settings]
  Gan to Kagaku Ryoho. Cancer & Chemotherapy. Nov, 2019  |   Pubmed ID: 31748471
• Identification of a Genomic Enhancer That Enforces Proper Apoptosis Induction in Thymic Negative Selection
  Nature Communications. 06, 2019  |   Pubmed ID: 31197149
• Novel Hybrid Three-dimensional Artificial Liver Using Human Induced Pluripotent Stem Cells and a Rat Decellularized Liver Scaffold
  Regenerative Therapy. Jun, 2019  |   Pubmed ID: 31032388
• Secreted PD-L1 Variants Mediate Resistance to PD-L1 Blockade Therapy in Non-small Cell Lung Cancer
  The Journal of Experimental Medicine. Apr, 2019  |   Pubmed ID: 30872362
• Suppression Effect on IFN-γ of Adipose Tissue-derived Mesenchymal Stem Cells Isolated from β2-microglobulin-deficient Mice
  Experimental and Therapeutic Medicine. Nov, 2018  |   Pubmed ID: 30344701
• Three-step Transcriptional Priming That Drives the Commitment of Multipotent Progenitors Toward B Cells
  Genes & Development. 01, 2018  |   Pubmed ID: 29440259
• Cloning and Expansion of Antigen-specific T Cells Using IPS Cell Technology: Development of "off-the-shelf" T Cells for the Use in Allogeneic Transfusion Settings
  International Journal of Hematology. Mar, 2018  |   Pubmed ID: 29388165
• NK Cell Alloreactivity Against KIR-Ligand-Mismatched HLA-Haploidentical Tissue Derived from HLA Haplotype-Homozygous IPSCs
  Stem Cell Reports. 09, 2017  |   Pubmed ID: 28867344
• Recurrent SPI1 (PU.1) Fusions in High-risk Pediatric T Cell Acute Lymphoblastic Leukemia
  Nature Genetics. Aug, 2017  |   Pubmed ID: 28671687
• The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development
  Immunity. 05, 2017  |   Pubmed ID: 28514688
• Conversion of T Cells to B Cells by Inactivation of Polycomb-mediated Epigenetic Suppression of the B-lineage Program
  Genes & Development. 11, 2016  |   Pubmed ID: 27913604
• Regeneration of CD8αβ T Cells from T-cell-Derived IPSC Imparts Potent Tumor Antigen-Specific Cytotoxicity
  Cancer Research. 12, 2016  |   Pubmed ID: 27872100
• Heterogeneous Fibroblasts Underlie Age-dependent Tertiary Lymphoid Tissues in the Kidney
  JCI Insight. 07, 2016  |   Pubmed ID: 27699223
• Regeneration of Tumor Antigen-specific CTLs Utilizing IPS Technology
  [Rinsho Ketsueki] The Japanese Journal of Clinical Hematology. 08, 2016  |   Pubmed ID: 27599425
• Transient Tcf3 Gene Repression by TALE-Transcription Factor Targeting
  Applied Biochemistry and Biotechnology. Dec, 2016  |   Pubmed ID: 27406037
• Aberrant PD-L1 Expression Through 3'-UTR Disruption in Multiple Cancers
  Nature. 06, 2016  |   Pubmed ID: 27281199
• Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells
  PLoS Genetics. Jan, 2016  |   Pubmed ID: 26789017
• Induced Developmental Arrest of Early Hematopoietic Progenitors Leads to the Generation of Leukocyte Stem Cells
  Stem Cell Reports. Nov, 2015  |   Pubmed ID: 26607950
• CNOT3 Contributes to Early B Cell Development by Controlling Igh Rearrangement and P53 MRNA Stability
  The Journal of Experimental Medicine. Aug, 2015  |   Pubmed ID: 26238124
• BTB-ZF Protein Znf131 Regulates Cell Growth of Developing and Mature T Cells
  Journal of Immunology (Baltimore, Md. : 1950). Aug, 2015  |   Pubmed ID: 26136427
• The E-Id Protein Axis Modulates the Activities of the PI3K-AKT-mTORC1-Hif1a and C-myc/p19Arf Pathways to Suppress Innate Variant TFH Cell Development, Thymocyte Expansion, and Lymphomagenesis
  Genes & Development. Feb, 2015  |   Pubmed ID: 25691468
• Indication for Neoadjuvant Chemotherapy in Patients with Colorectal Liver Metastases Based on a Nomogram That Predicts Disease-free Survival
  Journal of Hepato-biliary-pancreatic Sciences. Dec, 2014  |   Pubmed ID: 25155418
• TCF-1 and LEF-1 Act Upstream of Th-POK to Promote the CD4(+) T Cell Fate and Interact with Runx3 to Silence Cd4 in CD8(+) T Cells
  Nature Immunology. Jul, 2014  |   Pubmed ID: 24836425
• Differential Roles of Epigenetic Changes and Foxp3 Expression in Regulatory T Cell-specific Transcriptional Regulation
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2014  |   Pubmed ID: 24706905
• Loss of MTOR Complex 1 Induces Developmental Blockage in Early T-lymphopoiesis and Eradicates T-cell Acute Lymphoblastic Leukemia Cells
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2014  |   Pubmed ID: 24567410
• Direct Hematological Toxicity and Illegitimate Chromosomal Recombination Caused by the Systemic Activation of CreERT2
  Journal of Immunology (Baltimore, Md. : 1950). May, 2009  |   Pubmed ID: 19380810
• Regulation of T Cell Receptor Beta Gene Rearrangements and Allelic Exclusion by the Helix-loop-helix Protein, E47
  Immunity. Dec, 2007  |   Pubmed ID: 18093539
• Impaired T-cell Differentiation in the Thymus at the Early Stages of Acute Pathogenic Chimeric Simian-human Immunodeficiency Virus (SHIV) Infection in Contrast to Less Pathogenic SHIV Infection
  Microbes and Infection. May, 2006  |   Pubmed ID: 16702011
• Prethymic T-cell Development Defined by the Expression of Paired Immunoglobulin-like Receptors
  The EMBO Journal. Dec, 2005  |   Pubmed ID: 16292344
• Intrathymic Effect of Acute Pathogenic SHIV Infection on T-lineage Cells in Newborn Macaques
  Microbiology and Immunology. 2005  |   Pubmed ID: 16034211
• Thymic Anlage is Colonized by Progenitors Restricted to T, NK, and Dendritic Cell Lineages
  Journal of Immunology (Baltimore, Md. : 1950). Mar, 2005  |   Pubmed ID: 15728458
• Analyses of Peripheral Blood Mononuclear Cells in Operational Tolerance After Pediatric Living Donor Liver Transplantation
  American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Dec, 2004  |   Pubmed ID: 15575917
• Identification of the Earliest Prethymic T-cell Progenitors in Murine Fetal Blood
  Blood. Jan, 2004  |   Pubmed ID: 14512296
• T/NK Bipotent Progenitors in the Thymus Retain the Potential to Generate Dendritic Cells
  Journal of Immunology (Baltimore, Md. : 1950). Oct, 2003  |   Pubmed ID: 14500634
• Antigen-driven T Cell Anergy and Defective Memory T Cell Response Via Deregulated Rap1 Activation in SPA-1-deficient Mice
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2003  |   Pubmed ID: 12958214
• Myeloproliferative Stem Cell Disorders by Deregulated Rap1 Activation in SPA-1-deficient Mice
  Cancer Cell. Jul, 2003  |   Pubmed ID: 12892713
• Extensive Proliferation of T Cell Lineage-restricted Progenitors in the Thymus: an Essential Process for Clonal Expression of Diverse T Cell Receptor Beta Chains
  European Journal of Immunology. Mar, 2003  |   Pubmed ID: 12616481
• The Common Myelolymphoid Progenitor: a Key Intermediate Stage in Hemopoiesis Generating T and B Cells
  Journal of Immunology (Baltimore, Md. : 1950). Oct, 2002  |   Pubmed ID: 12244141
• Commitment to Natural Killer Cells Requires the Helix-loop-helix Inhibitor Id2
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2001  |   Pubmed ID: 11296270
• Commitment of Common T/Natural Killer (NK) Progenitors to Unipotent T and NK Progenitors in the Murine Fetal Thymus Revealed by a Single Progenitor Assay
  The Journal of Experimental Medicine. Dec, 1999  |   Pubmed ID: 10587352
• A Cell-autonomous Requirement for CXCR4 in Long-term Lymphoid and Myeloid Reconstitution
  Proceedings of the National Academy of Sciences of the United States of America. May, 1999  |   Pubmed ID: 10318941