Hiroshi Matsuura Department of Physiology Shiga University of Medical Science Biography Publications Institution JoVE Articles Hiroshi Matsuura has not added a biography. If you are Hiroshi Matsuura and would like to personalize this page please email our Author Liaison for assistance. Publications Elevation of Propofol Sensitivity of Cardiac I Channel by KCNE1 Polymorphism D85N British Journal of Pharmacology. Mar, 2021 | Pubmed ID: 33763865 Positive Inotropic Effects of ATP Released the Maxi-Anion Channel in Langendorff-Perfused Mouse Hearts Subjected to Ischemia-Reperfusion Frontiers in Cell and Developmental Biology. 2021 | Pubmed ID: 33553176 A Computational Analysis of the Effect of Sevoflurane in a Human Ventricular Cell Model of Long QT Syndrome: Importance of Repolarization Reserve in the QT-prolonging Effect of Sevoflurane European Journal of Pharmacology. Sep, 2020 | Pubmed ID: 32710951 Open-channel Blocking Action of Volatile Anaesthetics Desflurane and Sevoflurane on Human Voltage-gated K 1.5 Channel British Journal of Pharmacology. 08, 2020 | Pubmed ID: 32436224 Identification of Transmembrane Protein 168 Mutation in Familial Brugada Syndrome FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 05, 2020 | Pubmed ID: 32175648 Anesthetic Management of a Patient With Type 1 Long QT Syndrome Using Combined Epidural-Spinal Anesthesia for Caesarean Section: Perioperative Approach Based on Ion Channel Function Journal of Cardiothoracic and Vascular Anesthesia. Feb, 2020 | Pubmed ID: 31371065 A De Novo Gain-of-function KCND3 Mutation in Early Repolarization Syndrome Heart Rhythm. 11, 2019 | Pubmed ID: 31173922 Identification of Verapamil Binding Sites Within Human Kv1.5 Channel Using Mutagenesis and Docking Simulation Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2019 | Pubmed ID: 30816676 A Trafficking-deficient KCNQ1 Mutation, T587M, Causes a Severe Phenotype of Long QT Syndrome by Interfering with Intracellular HERG Transport Journal of Cardiology. 05, 2019 | Pubmed ID: 30591322 Long-term 4-AP Treatment Facilitates Functional Expression of Human Kv1.5 Channel European Journal of Pharmacology. Feb, 2019 | Pubmed ID: 30552904 Combined Antitumor Effects of P-5m Octapeptide and 5-fluorouracil on a Murine Model of H22 Hepatoma Ascites Experimental and Therapeutic Medicine. Sep, 2018 | Pubmed ID: 30186375 A Novel Mutation Identified in a Patient with Timothy Syndrome Without Syndactyly Exerts Both Marked Loss- and Gain-of-function Effects HeartRhythm Case Reports. Jul, 2018 | Pubmed ID: 30023270 P2X7 Ionotropic Receptor is Functionally Expressed in Rabbit Articular Chondrocytes and Mediates Extracellular ATP Cytotoxicity Purinergic Signalling. 09, 2018 | Pubmed ID: 29845461 A Simple Antegrade Perfusion Method for Isolating Viable Single Cardiomyocytes from Neonatal to Aged Mice Physiological Reports. 05, 2018 | Pubmed ID: 29696821 Postnatal Developmental Changes in the Sensitivity of L-type Ca Channel to Inhibition by Verapamil in a Mouse Heart Model Pediatric Research. 06, 2018 | Pubmed ID: 29554082 Correction To: Heterogeneous Functional Expression of the Sustained Inward Na Current in Guinea Pig Sinoatrial Node Cells Pflugers Archiv : European Journal of Physiology. 06, 2018 | Pubmed ID: 29480330 A HERG Mutation E1039X Produced a Synergistic Lesion on I Together with KCNQ1-R174C Mutation in a LQTS Family with Three Compound Mutations Scientific Reports. 02, 2018 | Pubmed ID: 29449639 Transient Receptor Potential Canonical Channel Blockers Improve Ventricular Contractile Functions After Ischemia/Reperfusion in a Langendorff-perfused Mouse Heart Model Journal of Cardiovascular Pharmacology. 04, 2018 | Pubmed ID: 29389740 Interactions of Propofol With Human Voltage-gated Kv1.5 Channel Determined by Docking Simulation and Mutagenesis Analyses Journal of Cardiovascular Pharmacology. 01, 2018 | Pubmed ID: 29283926 Heterogeneous Functional Expression of the Sustained Inward Na Current in Guinea Pig Sinoatrial Node Cells Pflugers Archiv : European Journal of Physiology. 03, 2018 | Pubmed ID: 29197941 Novel Intracellular Transport-refractory Mutations in KCNH2 Identified in Patients with Symptomatic Long QT Syndrome Journal of Cardiology. 04, 2018 | Pubmed ID: 29146210 The Organic Anion Transporter SLCO2A1 Constitutes the Core Component of the Maxi-Cl Channel The EMBO Journal. 11, 2017 | Pubmed ID: 29046334 Ca1.3 L-type Ca Channel Contributes to the Heartbeat by Generating a Dihydropyridine-sensitive Persistent Na Current Scientific Reports. 08, 2017 | Pubmed ID: 28801600 Ionic Mechanisms of the Action of Anaesthetics on Sinoatrial Node Automaticity European Journal of Pharmacology. Nov, 2017 | Pubmed ID: 28800884 Identification of Cardiac Progenitors That Survive in the Ischemic Human Heart After Ventricular Myocyte Death Scientific Reports. 01, 2017 | Pubmed ID: 28120944 Contribution of a KCNH2 Variant in Genotyped Long QT Syndrome: Romano-Ward Syndrome Under Double Mutations and Acquired Long QT Syndrome Under Heterozygote Journal of Cardiology. 07, 2017 | Pubmed ID: 27816319 Regulation of Human Cardiac Kv1.5 Channels by Extracellular Acidification Pflugers Archiv : European Journal of Physiology. 11, 2016 | Pubmed ID: 27796577 Serum Albumin Attenuates the Open-channel Blocking Effects of Propofol on the Human Kv1.5 Channel European Journal of Pharmacology. Jul, 2016 | Pubmed ID: 27164421 Lidocaine Induces ROCK-dependent Membrane Blebbing and Subsequent Cell Death in Rabbit Articular Chondrocytes Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 05, 2016 | Pubmed ID: 26519731 Putative Binding Sites for Arachidonic Acid on the Human Cardiac Kv 1.5 Channel British Journal of Pharmacology. Nov, 2015 | Pubmed ID: 26292661 Interaction of Propofol with Voltage-gated Human Kv1.5 Channel Through Specific Amino Acids Within the Pore Region European Journal of Pharmacology. Oct, 2015 | Pubmed ID: 26256861 Phosphatidylinositol4-phosphate 5-kinase Prevents the Decrease in the HERG Potassium Current Induced by Gq Protein-coupled Receptor Stimulation Journal of Pharmacological Sciences. Jan, 2015 | Pubmed ID: 25704028 Ionic Mechanisms Underlying the Negative Chronotropic Action of Propofol on Sinoatrial Node Automaticity in Guinea Pig Heart British Journal of Pharmacology. Feb, 2015 | Pubmed ID: 25220338 Ca2+/calmodulin Potentiates I Ks in Sinoatrial Node Cells by Activating Ca2+/calmodulin-dependent Protein Kinase II Pflugers Archiv : European Journal of Physiology. Feb, 2015 | Pubmed ID: 24737247 Prion Protein- and Cardiac Troponin T-marked Interstitial Cells from the Adult Myocardium Spontaneously Develop into Beating Cardiomyocytes Scientific Reports. Dec, 2014 | Pubmed ID: 25466571 Novel Intracellular Mediator of Adiponectin Secretion from Adipocytes The Journal of Physiology. Dec, 2014 | Pubmed ID: 25448182 Long QT Syndrome Type 8: Novel CACNA1C Mutations Causing QT Prolongation and Variant Phenotypes Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. Dec, 2014 | Pubmed ID: 24728418 Improved Functional Expression of Human Cardiac Kv1.5 Channels and Trafficking-defective Mutants by Low Temperature Treatment PloS One. 2014 | Pubmed ID: 24663680 Direct Negative Chronotropic Action of Desflurane on Sinoatrial Node Pacemaker Activity in the Guinea Pig Heart Anesthesiology. Jun, 2014 | Pubmed ID: 24518231 Gain-of-function KCNH2 Mutations in Patients with Brugada Syndrome Journal of Cardiovascular Electrophysiology. May, 2014 | Pubmed ID: 24400717 A Molecular Mechanism for Adrenergic-induced Long QT Syndrome Journal of the American College of Cardiology. Mar, 2014 | Pubmed ID: 24184248 Cardiac Channelopathies Associated with Infantile Fatal Ventricular Arrhythmias: from the Cradle to the Bench Journal of Cardiovascular Electrophysiology. Jan, 2014 | Pubmed ID: 24112685 A Novel KCNQ1 Missense Mutation Identified in a Patient with Juvenile-onset Atrial Fibrillation Causes Constitutively Open IKs Channels Heart Rhythm. Jan, 2014 | Pubmed ID: 24096004 Irbesartan-mediated AT1 Receptor Blockade Attenuates Hyposmotic-induced Enhancement of I Ks Current and Prevents Shortening of Action Potential Duration in Atrial Myocytes Journal of the Renin-angiotensin-aldosterone System : JRAAS. Dec, 2014 | Pubmed ID: 23386284 Remifentanil Has a Minimal Direct Effect on Sinoatrial Node Pacemaker Activity in the Guinea Pig Heart Anesthesia and Analgesia. Nov, 2013 | Pubmed ID: 24108259 The COX-2 Selective Blocker Etodolac Inhibits TNFα-induced Apoptosis in Isolated Rabbit Articular Chondrocytes International Journal of Molecular Sciences. Sep, 2013 | Pubmed ID: 24084720 Sevoflurane Protects Ventricular Myocytes Against Oxidative Stress-induced Cellular Ca2+ Overload and Hypercontracture Anesthesiology. Sep, 2013 | Pubmed ID: 23571639 Ischemic Survival and Constitutively Active Autophagy in Self-beating Atypically-shaped Cardiomyocytes (ACMs): Characterization of a New Subpopulation of Heart Cells The Journal of Physiological Sciences : JPS. Jan, 2013 | Pubmed ID: 23055023 Phenotype Variability in Patients Carrying KCNJ2 Mutations Circulation. Cardiovascular Genetics. Jun, 2012 | Pubmed ID: 22589293 Postnatal Developmental Decline in IK1 in Mouse Ventricular Myocytes Isolated by the Langendorff Perfusion Method: Comparison with the Chunk Method Pflugers Archiv : European Journal of Physiology. Apr, 2012 | Pubmed ID: 22415213 GHGKHKNK Octapeptide (P-5m) Inhibits Metastasis of HCCLM3 Cell Lines Via Regulation of MMP-2 Expression in in Vitro and in Vivo Studies Molecules (Basel, Switzerland). Feb, 2012 | Pubmed ID: 22395332 Inhibitory Effects of Sevoflurane on Pacemaking Activity of Sinoatrial Node Cells in Guinea-pig Heart British Journal of Pharmacology. Aug, 2012 | Pubmed ID: 22356456 17β-Oestradiol Inhibits Doxorubicin-induced Apoptosis Via Block of the Volume-sensitive Cl(-) Current in Rabbit Articular Chondrocytes British Journal of Pharmacology. May, 2012 | Pubmed ID: 22142024 Autophagy is Constitutively Active in Normal Mouse Sino-atrial Nodal Cells Acta Histochemica Et Cytochemica. Oct, 2011 | Pubmed ID: 22096262 Identification and Functional Characterization of KCNQ1 Mutations Around the Exon 7-intron 7 Junction Affecting the Splicing Process Biochimica Et Biophysica Acta. Nov, 2011 | Pubmed ID: 21810471 Sevoflurane Protects Ventricular Myocytes from Ca2+ Paradox-mediated Ca2+ Overload by Blocking the Activation of Transient Receptor Potential Canonical Channels Anesthesiology. Sep, 2011 | Pubmed ID: 21799395 Lysophosphatidylcholine Enhances I(Ks) Currents in Cardiac Myocytes Through Activation of G Protein, PKC and Rho Signaling Pathways Journal of Molecular and Cellular Cardiology. Jan, 2011 | Pubmed ID: 20950624 Atrioventricular Block-induced Torsades De Pointes with Clinical and Molecular Backgrounds Similar to Congenital Long QT Syndrome Circulation Journal : Official Journal of the Japanese Circulation Society. Nov, 2010 | Pubmed ID: 20975234 Presence and Functional Role of the Rapidly Activating Delayed Rectifier K(+) Current in Left and Right Atria of Adult Mice European Journal of Pharmacology. Dec, 2010 | Pubmed ID: 20826138 Ca2+ Paradox Injury Mediated Through TRPC Channels in Mouse Ventricular Myocytes British Journal of Pharmacology. Dec, 2010 | Pubmed ID: 20718730 Characterization of the Rapidly Activating Delayed Rectifier Potassium Current, I (Kr), in HL-1 Mouse Atrial Myocytes The Journal of Membrane Biology. Jun, 2010 | Pubmed ID: 20490473 Self-beating Atypically Shaped Cardiomyocytes Survive a Long-term Postnatal Development While Preserving the Expression of Fetal Cardiac Genes in Mice The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Jun, 2010 | Pubmed ID: 20197490 KCNE2 Modulation of Kv4.3 Current and Its Potential Role in Fatal Rhythm Disorders Heart Rhythm. 2010 | Pubmed ID: 20042375 Latent Genetic Backgrounds and Molecular Pathogenesis in Drug-induced Long-QT Syndrome Circulation. Arrhythmia and Electrophysiology. Oct, 2009 | Pubmed ID: 19843919 Regulatory Role of Tyrosine Phosphorylation in the Swelling-activated Chloride Current in Isolated Rabbit Articular Chondrocytes The Journal of Physiology. Aug, 2009 | Pubmed ID: 19528252 Adrenergic Regulation of the Rapid Component of Delayed Rectifier K+ Current: Implications for Arrhythmogenesis in LQT2 Patients Heart Rhythm. Jul, 2009 | Pubmed ID: 19419905 Angiotensin II Type 1 Receptor Mediates Partially Hyposmotic-induced Increase of I (Ks) Current in Guinea Pig Atrium Pflugers Archiv : European Journal of Physiology. Sep, 2009 | Pubmed ID: 19404674 A Novel Type of Self-beating Cardiomyocytes in Adult Mouse Ventricles Biochemical and Biophysical Research Communications. Apr, 2009 | Pubmed ID: 19222989 Swelling-activated Cl(-) Current in Isolated Rabbit Articular Chondrocytes: Inhibition by Arachidonic Acid Journal of Pharmacological Sciences. Feb, 2009 | Pubmed ID: 19212094 Hydroxyzine, a First Generation H(1)-receptor Antagonist, Inhibits Human Ether-a-go-go-related Gene (HERG) Current and Causes Syncope in a Patient with the HERG Mutation Journal of Pharmacological Sciences. Dec, 2008 | Pubmed ID: 19057127 Cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate and Nordihydroguaiaretic Acid Inhibit Human Kv1.5 Currents Independently of Lipoxygenase European Journal of Pharmacology. Dec, 2008 | Pubmed ID: 18930721 Functional Analysis of Rod Monochromacy-associated Missense Mutations in the CNGA3 Subunit of the Cone Photoreceptor CGMP-gated Channel Biochemical and Biophysical Research Communications. Oct, 2007 | Pubmed ID: 17693388 Inhibitory Action of Protein Kinase Cbeta Inhibitor on Tetrodotoxin-resistant Na+ Current in Small Dorsal Root Ganglion Neurons in Diabetic Rats Neuroscience Letters. Apr, 2007 | Pubmed ID: 17339081 Modulation of Functional Properties of KCNQ1 Channel by Association of KCNE1 and KCNE2 Biochemical and Biophysical Research Communications. Jun, 2006 | Pubmed ID: 16631607 Effect of Protein Kinase Cbeta Inhibitor on Ca2+ Homeostasis in Diabetic Sensory Neurons Neuroreport. Apr, 2006 | Pubmed ID: 16603936 Monkey Embryonic Stem Cells Differentiate into Adipocytes in Vitro Cloning and Stem Cells. 2006 | Pubmed ID: 16571072 Angiotensin II Potentiates the Slow Component of Delayed Rectifier K+ Current Via the AT1 Receptor in Guinea Pig Atrial Myocytes Circulation. Mar, 2006 | Pubmed ID: 16534027 In Vitro Expression of Natriuretic Peptides in Cardiomyocytes Differentiated from Monkey Embryonic Stem Cells Biochemical and Biophysical Research Communications. Feb, 2006 | Pubmed ID: 16378593 Effect of ATP on Preadipocyte Migration and Adipocyte Differentiation by Activating P2Y Receptors in 3T3-L1 Cells The Biochemical Journal. Jan, 2006 | Pubmed ID: 16143005 Open-state Unblock Characterizes Acute Inhibition of I Potassium Current by Amiodarone in Guinea Pig Ventricular Myocytes Journal of Cardiovascular Electrophysiology. Mar, 2005 | Pubmed ID: 15817093 Regulation of the Muscarinic K+ Channel by Extracellular ATP Through Membrane Phosphatidylinositol 4,5-bisphosphate in Guinea-pig Atrial Myocytes British Journal of Pharmacology. May, 2005 | Pubmed ID: 15765102 Responses of the Sustained Inward Current to Autonomic Agonists in Guinea-pig Sino-atrial Node Pacemaker Cells British Journal of Pharmacology. Mar, 2005 | Pubmed ID: 15678089 Regulation of Cardiac IKs Potassium Current by Membrane Phosphatidylinositol 4,5-bisphosphate The Journal of Biological Chemistry. Dec, 2004 | Pubmed ID: 15364935 Functional Role of HCngb3 in Regulation of Human Cone Cng Channel: Effect of Rod Monochromacy-associated Mutations in HCNGB3 on Channel Function Investigative Ophthalmology & Visual Science. Jul, 2004 | Pubmed ID: 15223812 Actin Filaments Play a Permissive Role in the Inhibition of Store-operated Ca2+ Entry by Extracellular ATP in Rat Brown Adipocytes The Biochemical Journal. Jul, 2004 | Pubmed ID: 15107014 Cytosolic Ca2+ Under High Glucose with Suppressed Na+/K+ Pump Activity in Rat Sensory Neurons Neuroreport. Jan, 2004 | Pubmed ID: 15106857 Properties of the Na+/K+ Pump Current in Small Neurons from Adult Rat Dorsal Root Ganglia British Journal of Pharmacology. Apr, 2003 | Pubmed ID: 12721107 Multiple P2 Receptors Contribute to a Transient Increase in Intracellular Ca2+ Concentration in ATP-stimulated Rat Brown Adipocytes Experimental Physiology. Nov, 2002 | Pubmed ID: 12447447 Blocking Action of Chromanol 293B on the Slow Component of Delayed Rectifier K(+) Current in Guinea-pig Sino-atrial Node Cells British Journal of Pharmacology. Sep, 2002 | Pubmed ID: 12208783 Potentiation of Slow Component of Delayed Rectifier K(+) Current by CGMP Via Two Distinct Mechanisms: Inhibition of Phosphodiesterase 3 and Activation of Protein Kinase G British Journal of Pharmacology. Sep, 2002 | Pubmed ID: 12183338 Rapidly and Slowly Activating Components of Delayed Rectifier K(+) Current in Guinea-pig Sino-atrial Node Pacemaker Cells The Journal of Physiology. May, 2002 | Pubmed ID: 11986371 Inhibition of Store-operated Ca2+ Entry by Extracellular ATP in Rat Brown Adipocytes The Journal of Physiology. Dec, 1999 | Pubmed ID: 10601492 Un Método De Perfusión Anterógrada Para El Aislamiento De Cardiomiocitos De Ratones Mariko Omatsu-Kanbe1, Ryo Fukunaga1, Xinya Mi1, Hiroshi Matsuura1 1Department of Physiology, Shiga University of Medical Science JoVE 61866 Biology
Un Método De Perfusión Anterógrada Para El Aislamiento De Cardiomiocitos De Ratones Mariko Omatsu-Kanbe1, Ryo Fukunaga1, Xinya Mi1, Hiroshi Matsuura1 1Department of Physiology, Shiga University of Medical Science JoVE 61866 Biology