Holger Jahr Department of Orthopedic Surgery Maastricht UMC+ Biography Publications Institution JoVE Articles Holger Jahr has not added a biography. If you are Holger Jahr and would like to personalize this page please email our Author Liaison for assistance. Publications The Antimicrobial Peptide Human Beta-Defensin-3 Is Induced by Platelet-Released Growth Factors in Primary Keratinocytes Mediators of Inflammation. 2017 | Pubmed ID: 28811680 Platelet-Released Growth Factors Induce Differentiation of Primary Keratinocytes Mediators of Inflammation. 2017 | Pubmed ID: 28808357 The Protective Effect of Platelet Released Growth Factors and Bone Augmentation (Bio-Oss(®)) on Ethanol Impaired Osteoblasts Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft. Jul, 2017 | Pubmed ID: 28774818 Functional in Situ Assessment of Human Articular Cartilage Using MRI: a Whole-knee Joint Loading Device Biomechanics and Modeling in Mechanobiology. Jul, 2017 | Pubmed ID: 28685238 Platelet-released Growth Factors Induce Psoriasin in Keratinocytes: Implications for the Cutaneous Barrier Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft. Sep, 2017 | Pubmed ID: 28552640 Functional MR Imaging Mapping of Human Articular Cartilage Response to Loading Radiology. Feb, 2017 | Pubmed ID: 27564133 Ex Vivo Quantitative Multiparametric MRI Mapping of Human Meniscus Degeneration Skeletal Radiology. Dec, 2016 | Pubmed ID: 27639388 Effect of Platelet Mediator Concentrate (PMC) on Achilles Tenocytes: an in Vitro Study BMC Musculoskeletal Disorders. Jul, 2016 | Pubmed ID: 27448409 Polarization-sensitive Optical Coherence Tomography-based Imaging, Parameterization, and Quantification of Human Cartilage Degeneration Journal of Biomedical Optics. Jul, 2016 | Pubmed ID: 27447953 Cell Surface Syndecan-1 Contributes to Binding and Function of Macrophage Migration Inhibitory Factor (MIF) on Epithelial Tumor Cells Biochimica Et Biophysica Acta. Apr, 2016 | Pubmed ID: 26852939 Quantitative OCT and MRI Biomarkers for the Differentiation of Cartilage Degeneration Skeletal Radiology. Apr, 2016 | Pubmed ID: 26783011 Towards Optical Coherence Tomography-based Elastographic Evaluation of Human Cartilage Journal of the Mechanical Behavior of Biomedical Materials. Mar, 2016 | Pubmed ID: 26700573 Detecting Early Stage Osteoarthritis by Optical Coherence Tomography? Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 2015 | Pubmed ID: 26862954 HDACi and Nrf2: Not from Alpha to Omega but from Acetylation to OA Arthritis Research & Therapy. Dec, 2015 | Pubmed ID: 26714479 3D Human Cartilage Surface Characterization by Optical Coherence Tomography Physics in Medicine and Biology. Oct, 2015 | Pubmed ID: 26394374 A Cytoplasmic C-terminal Fragment of Syndecan-1 is Generated by Sequential Proteolysis and Antagonizes Syndecan-1 Dependent Lung Tumor Cell Migration Oncotarget. Oct, 2015 | Pubmed ID: 26378057 Abrasion Arthroplasty Increases Mesenchymal Stem Cell Content of Postoperative Joint Effusions BMC Musculoskeletal Disorders. Sep, 2015 | Pubmed ID: 26364138 Evaluation of Single-Impact-Induced Cartilage Degeneration by Optical Coherence Tomography BioMed Research International. 2015 | Pubmed ID: 26229959 Optical Coherence Tomography-based Parameterization and Quantification of Articular Cartilage Surface Integrity Biomedical Optics Express. Jul, 2015 | Pubmed ID: 26203369 A Transmembrane C-terminal Fragment of Syndecan-1 is Generated by the Metalloproteinase ADAM17 and Promotes Lung Epithelial Tumor Cell Migration and Lung Metastasis Formation Cellular and Molecular Life Sciences : CMLS. Oct, 2015 | Pubmed ID: 25912030 Physicochemical and Biomechanical Stimuli in Cell-based Articular Cartilage Repair Current Rheumatology Reports. Mar, 2015 | Pubmed ID: 25828845 Three-dimensional Imaging and Analysis of Human Cartilage Degeneration Using Optical Coherence Tomography Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. May, 2015 | Pubmed ID: 25641346 Osteostatin-coated Porous Titanium Can Improve Early Bone Regeneration of Cortical Bone Defects in Rats Tissue Engineering. Part A. May, 2015 | Pubmed ID: 25627039 Mechanical Forces Induce Changes in VEGF and VEGFR-1/sFlt-1 Expression in Human Chondrocytes International Journal of Molecular Sciences. Sep, 2014 | Pubmed ID: 25257525 Nrf2 Deficiency Impairs Fracture Healing in Mice Calcified Tissue International. Oct, 2014 | Pubmed ID: 25096517 Morphometric Grading of Osteoarthritis by Optical Coherence Tomography--an Ex Vivo Study Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Oct, 2014 | Pubmed ID: 24992396 Role of Platelet-released Growth Factors in Detoxification of Reactive Oxygen Species in Osteoblasts Bone. Aug, 2014 | Pubmed ID: 24798492 GREM1, FRZB and DKK1 MRNA Levels Correlate with Osteoarthritis and Are Regulated by Osteoarthritis-associated Factors Arthritis Research & Therapy. Sep, 2013 | Pubmed ID: 24286177 A Universal Method for Sequential Immunofluorescent Analysis of Chromatin and Chromatin-associated Proteins on Chromosome Spreads Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. Aug, 2013 | Pubmed ID: 23896649 Enhanced Bone Regeneration of Cortical Segmental Bone Defects Using Porous Titanium Scaffolds Incorporated with Colloidal Gelatin Gels for Time- and Dose-controlled Delivery of Dual Growth Factors Tissue Engineering. Part A. Dec, 2013 | Pubmed ID: 23822814 Hsp90 Inhibition Protects Against Biomechanically Induced Osteoarthritis in Rats Arthritis and Rheumatism. Aug, 2013 | Pubmed ID: 23666904 Selective Laser Melting-produced Porous Titanium Scaffolds Regenerate Bone in Critical Size Cortical Bone Defects Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. May, 2013 | Pubmed ID: 23255164 Unfocused Extracorporeal Shock Waves Induce Anabolic Effects in Osteoporotic Rats Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. May, 2013 | Pubmed ID: 23239548 Osmolarity Determines the in Vitro Chondrogenic Differentiation Capacity of Progenitor Cells Via Nuclear Factor of Activated T-cells 5 Bone. Mar, 2013 | Pubmed ID: 23219947 Inhibiting Calcineurin Activity Under Physiologic Tonicity Elevates Anabolic but Suppresses Catabolic Chondrocyte Markers Arthritis and Rheumatism. Jun, 2012 | Pubmed ID: 22231955 Calcineurin/nuclear Factor of Activated T Cells (NFAT) Signaling in Cobalt-chromium-molybdenum (CoCrMo) Particles-induced Tumor Necrosis Factor-α (TNFα) Secretion in MLO-Y4 Osteocytes Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Dec, 2011 | Pubmed ID: 21557302 A Role for Aurora C in the Chromosomal Passenger Complex During Human Preimplantation Embryo Development Human Reproduction (Oxford, England). Jul, 2011 | Pubmed ID: 21493633 Clinically Translatable Cell Tracking and Quantification by MRI in Cartilage Repair Using Superparamagnetic Iron Oxides PloS One. Feb, 2011 | Pubmed ID: 21373640 Differences in Cartilage-forming Capacity of Expanded Human Chondrocytes from Ear and Nose and Their Gene Expression Profiles Cell Transplantation. 2011 | Pubmed ID: 21054934 Stimulation of Osteogenic Differentiation in Human Osteoprogenitor Cells by Pulsed Electromagnetic Fields: an in Vitro Study BMC Musculoskeletal Disorders. Aug, 2010 | Pubmed ID: 20731873 Physiological Tonicity Improves Human Chondrogenic Marker Expression Through Nuclear Factor of Activated T-cells 5 in Vitro Arthritis Research & Therapy. 2010 | Pubmed ID: 20492652 Estrogen Modulates Iodoacetate-induced Gene Expression in Bovine Cartilage Explants Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. May, 2010 | Pubmed ID: 19953602 Stretch-induced Inhibition of Wnt/beta-catenin Signaling in Mineralizing Osteoblasts Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Mar, 2010 | Pubmed ID: 19780202 Fibroblast Growth Factor Receptors in in Vitro and in Vivo Chondrogenesis: Relating Tissue Engineering Using Adult Mesenchymal Stem Cells to Embryonic Development Tissue Engineering. Part A. Feb, 2010 | Pubmed ID: 19728793 The Role of Hypoxia in Bone Marrow-derived Mesenchymal Stem Cells: Considerations for Regenerative Medicine Approaches Tissue Engineering. Part B, Reviews. Apr, 2010 | Pubmed ID: 19698058 Calcineurin Inhibitors Promote Chondrogenic Marker Expression of Dedifferentiated Human Adult Chondrocytes Via Stimulation of Endogenous TGFbeta1 Production Tissue Engineering. Part A. Jan, 2010 | Pubmed ID: 19604038 Chondrogenic Priming of Human Bone Marrow Stromal Cells: a Better Route to Bone Repair? Tissue Engineering. Part C, Methods. Jun, 2009 | Pubmed ID: 19505182 In Vitro Model to Study Chondrogenic Differentiation in Tendinopathy The American Journal of Sports Medicine. Jun, 2009 | Pubmed ID: 19279223 Tendon Degeneration is Not Mediated by Regulation of Toll-like Receptors 2 and 4 in Human Tenocytes Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Aug, 2009 | Pubmed ID: 19148938 Angiogenic Capacity of Human Adipose-derived Stromal Cells During Adipogenic Differentiation: an in Vitro Study Tissue Engineering. Part A. Feb, 2009 | Pubmed ID: 18652540 Control of Oxygen Tension and PH in a Bioreactor for Cartilage Tissue Engineering Bio-medical Materials and Engineering. 2008 | Pubmed ID: 19065034 Obestatin Induction of Early-response Gene Expression in Gastrointestinal and Adipose Tissues and the Mediatory Role of G Protein-coupled Receptor, GPR39 Molecular Endocrinology (Baltimore, Md.). Jun, 2008 | Pubmed ID: 18337590 Effects of Iron Oxide Incorporation for Long Term Cell Tracking on MSC Differentiation in Vitro and in Vivo Biochemical and Biophysical Research Communications. May, 2008 | Pubmed ID: 18336785 Can Platelet-rich Plasma Enhance Tendon Repair? A Cell Culture Study The American Journal of Sports Medicine. Jun, 2008 | Pubmed ID: 18326832 Achilles Tendinosis: Changes in Biochemical Composition and Collagen Turnover Rate The American Journal of Sports Medicine. Sep, 2007 | Pubmed ID: 17478653 Intrinsic Differentiation Potential of Adolescent Human Tendon Tissue: an In-vitro Cell Differentiation Study BMC Musculoskeletal Disorders. Feb, 2007 | Pubmed ID: 17319938 Stretch-induced Modulation of Matrix Metalloproteinases in Mineralizing Osteoblasts Via Extracellular Signal-regulated Kinase-1/2 Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Jul, 2006 | Pubmed ID: 16705736 Identification of Acid-sensing Ion Channels in Bone Biochemical and Biophysical Research Communications. Nov, 2005 | Pubmed ID: 16185661 Tuning Haptotropic Rearrangements of Arene-chromium Complexes: Steric and Electronic Effects of Phosphorus Coligands Chemistry (Weinheim an Der Bergstrasse, Germany). Sep, 2005 | Pubmed ID: 16003815 Considerations on the Use of Ear Chondrocytes As Donor Chondrocytes for Cartilage Tissue Engineering Biorheology. 2004 | Pubmed ID: 15299273 Tunable Haptotropic Metal Migration in Fused Arenes: Towards Organometallic Switches Chemical Record (New York, N.Y.). 2004 | Pubmed ID: 15073874 Controlled Haptotropic Rearrangements--towards a Stereospecific Molecular Switch Based on Chiral Arene Chromium Complexes Chemical Communications (Cambridge, England). Dec, 2003 | Pubmed ID: 14680214 Visualizzando l'angiogenesi da microscopia multifotonica In Vivo in geneticamente 3D-PLGA/nHAp impalcatura per Calvarial riparazione di difetti ossei critici Jian Li1, Holger Jahr2,3, Wei Zheng4, Pei-Gen Ren1 1Center for Translational Medicine Research and Development, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 2Department of Orthopedic Surgery, Maastricht UMC+, 3Department of Orthopaedic Surgery, University Hospital RWTH, 4Research Laboratory for Biomedical Optics and Molecular Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences JoVE 55381 Bioengineering
Visualizzando l'angiogenesi da microscopia multifotonica In Vivo in geneticamente 3D-PLGA/nHAp impalcatura per Calvarial riparazione di difetti ossei critici Jian Li1, Holger Jahr2,3, Wei Zheng4, Pei-Gen Ren1 1Center for Translational Medicine Research and Development, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 2Department of Orthopedic Surgery, Maastricht UMC+, 3Department of Orthopaedic Surgery, University Hospital RWTH, 4Research Laboratory for Biomedical Optics and Molecular Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences JoVE 55381 Bioengineering
