Hong-Fen Guo

Publications

• Identification of Immunotherapy and Radioimmunotherapy Targets on Desmoplastic Small Round Cell Tumors
  Frontiers in Oncology. 2023  |   Pubmed ID: 37091153
• Targeting Tumor Vasculature to Improve Antitumor Activity of T Cells Armed Ex Vivo with T Cell Engaging Bispecific Antibody
  Journal for Immunotherapy of Cancer. Mar, 2023  |   Pubmed ID: 36990507
• Intraperitoneal Pretargeted Radioimmunotherapy for Colorectal Peritoneal Carcinomatosis
  Molecular Cancer Therapeutics. Jan, 2022  |   Pubmed ID: 34667111
• Novel Potent Anti-STEAP1 Bispecific Antibody to Redirect T Cells for Cancer Immunotherapy
  Journal for Immunotherapy of Cancer. Sep, 2021  |   Pubmed ID: 34497115
• T Cell Engaging Bispecific Antibodies Targeting CD33 IgV and IgC Domains for the Treatment of Acute Myeloid Leukemia
  Journal for Immunotherapy of Cancer. May, 2021  |   Pubmed ID: 34035113
• Potent Antitumor Effect of T Cells Armed with Anti-GD2 Bispecific Antibody
  Pediatric Blood & Cancer. Jul, 2021  |   Pubmed ID: 33844437
• A Self-Assembling and Disassembling (SADA) Bispecific Antibody (BsAb) Platform for Curative Two-step Pretargeted Radioimmunotherapy
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2021  |   Pubmed ID: 32958698
• Overcoming Leukemia Heterogeneity by Combining T Cell Engaging Bispecific Antibodies
  Journal for Immunotherapy of Cancer. Nov, 2020  |   Pubmed ID: 33239418
• Alpha Radioimmunotherapy Using Ac-proteus-DOTA for Solid Tumors - Safety at Curative Doses
  Theranostics. 2020  |   Pubmed ID: 33052220
• Interdomain Spacing and Spatial Configuration Drive the Potency of IgG-[L]-scFv T Cell Bispecific Antibodies
  Science Translational Medicine. Mar, 2020  |   Pubmed ID: 32161106
• An -Acetylgalactosamino Dendron-Clearing Agent for High-Therapeutic-Index DOTA-Hapten Pretargeted Radioimmunotherapy
  Bioconjugate Chemistry. Mar, 2020  |   Pubmed ID: 31891487
• Theranostic Pretargeted Radioimmunotherapy of Internalizing Solid Tumor Antigens in Human Tumor Xenografts in Mice: Curative Treatment of HER2-positive Breast Carcinoma
  Theranostics. 2018  |   Pubmed ID: 30429889
• Development of a Tetravalent Anti-GPA33/Anti-CD3 Bispecific Antibody for Colorectal Cancers
  Molecular Cancer Therapeutics. Oct, 2018  |   Pubmed ID: 30082472
• Curative Multicycle Radioimmunotherapy Monitored by Quantitative SPECT/CT-Based Theranostics, Using Bispecific Antibody Pretargeting Strategy in Colorectal Cancer
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Nov, 2017  |   Pubmed ID: 28705917
• Theranostic Pretargeted Radioimmunotherapy of Colorectal Cancer Xenografts in Mice Using Picomolar Affinity ⁸⁶Y- or ¹⁷⁷Lu-DOTA-Bn Binding ScFv C825/GPA33 IgG Bispecific Immunoconjugates
  European Journal of Nuclear Medicine and Molecular Imaging. May, 2016  |   Pubmed ID: 26596724
• Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3
  The Journal of Biological Chemistry. Dec, 2015  |   Pubmed ID: 26487718
• A Distinct Gene Expression Signature Characterizes Human Neuroblastoma Cancer Stem Cells
  Stem Cell Research. Sep, 2015  |   Pubmed ID: 26342562
• Alteration of Electrostatic Surface Potential Enhances Affinity and Tumor Killing Properties of Anti-ganglioside GD2 Monoclonal Antibody Hu3F8
  The Journal of Biological Chemistry. May, 2015  |   Pubmed ID: 25851904
• Preclinical Evaluation of Multistep Targeting of Diasialoganglioside GD2 Using an IgG-scFv Bispecific Antibody with High Affinity for GD2 and DOTA Metal Complex
  Molecular Cancer Therapeutics. Jul, 2014  |   Pubmed ID: 24944121
• In Silico Driven Redesign of a Clinically Relevant Antibody for the Treatment of GD2 Positive Tumors
  PloS One. 2013  |   Pubmed ID: 23696816
• Interstitial Infusion of Glioma-targeted Recombinant Immunotoxin 8H9scFv-PE38
  Molecular Cancer Therapeutics. Apr, 2010  |   Pubmed ID: 20371725
• MicroRNA MiR-29 Modulates Expression of Immunoinhibitory Molecule B7-H3: Potential Implications for Immune Based Therapy of Human Solid Tumors
  Cancer Research. Aug, 2009  |   Pubmed ID: 19584290
• Radioimmunotargeting of Human Rhabdomyosarcoma Using Monoclonal Antibody 8H9
  Cancer Biotherapy & Radiopharmaceuticals. Oct, 2005  |   Pubmed ID: 16248769
• Characteristics of Stem Cells from Human Neuroblastoma Cell Lines and in Tumors
  Neoplasia (New York, N.Y.). 2004  |   Pubmed ID: 15720811
• Anti-idiotypic Antibody Facilitates ScFv Chimeric Immune Receptor Gene Transduction and Clonal Expansion of Human Lymphocytes for Tumor Therapy
  Hybridoma and Hybridomics. Aug, 2003  |   Pubmed ID: 14511566
• Anti-idiotypic Antibody As the Surrogate Antigen for Cloning ScFv and Its Fusion Proteins
  Hybridoma and Hybridomics. Dec, 2002  |   Pubmed ID: 12573107
• Antigen-dependent CD28 Signaling Selectively Enhances Survival and Proliferation in Genetically Modified Activated Human Primary T Lymphocytes
  The Journal of Experimental Medicine. Aug, 1998  |   Pubmed ID: 9705944