Hong-Jian Zhu

Publications

• Ras Enhances TGF-β Signaling by Decreasing Cellular Protein Levels of Its Type II Receptor Negative Regulator SPSB1
  Cell Communication and Signaling : CCS. Mar, 2018  |   Pubmed ID: 29534718
• TGF-β and IL-6 Family Signalling Crosstalk: an Integrated Model
  Growth Factors (Chur, Switzerland). 06, 2017  |   Pubmed ID: 28948853
• Csk-homologous Kinase (Chk) is an Efficient Inhibitor of Src-family Kinases but a Poor Catalyst of Phosphorylation of Their C-terminal Regulatory Tyrosine
  Cell Communication and Signaling : CCS. 08, 2017  |   Pubmed ID: 28784162
• Mathematical Model of TGF-βsignalling: Feedback Coupling is Consistent with Signal Switching
  BMC Systems Biology. 04, 2017  |   Pubmed ID: 28407804
• Extracellular Vesicles: Their Role in Cancer Biology and Epithelial-mesenchymal Transition
  The Biochemical Journal. 01, 2017  |   Pubmed ID: 28008089
• Transformed MDCK Cells Secrete Elevated MMP1 That Generates LAMA5 Fragments Promoting Endothelial Cell Angiogenesis
  Scientific Reports. 06, 2016  |   Pubmed ID: 27324842
• Extracellular Vesicle Isolation and Characterization: Toward Clinical Application
  The Journal of Clinical Investigation. Apr, 2016  |   Pubmed ID: 27035807
• Oncogenic Epithelial Cell-derived Exosomes Containing Rac1 and PAK2 Induce Angiogenesis in Recipient Endothelial Cells
  Oncotarget. Apr, 2016  |   Pubmed ID: 26919098
• The C-terminal Tail Inhibitory Phosphorylation Sites of PTEN Regulate Its Intrinsic Catalytic Activity and the Kinetics of Its Binding to Phosphatidylinositol-4,5-bisphosphate
  Archives of Biochemistry and Biophysics. Dec, 2015  |   Pubmed ID: 26471078
• SPSB1, a Novel Negative Regulator of the Transforming Growth Factor-β Signaling Pathway Targeting the Type II Receptor
  The Journal of Biological Chemistry. Jul, 2015  |   Pubmed ID: 26032413
• YBX1/YB-1 Induces Partial EMT and Tumourigenicity Through Secretion of Angiogenic Factors into the Extracellular Microenvironment
  Oncotarget. May, 2015  |   Pubmed ID: 25980435
• Single Live Cell TGF-β Signalling Imaging: Breast Cancer Cell Motility and Migration is Driven by Sub-populations of Cells with Dynamic TGF-β-Smad3 Activity
  Molecular Cancer. Feb, 2015  |   Pubmed ID: 25744371
• Emerging Roles of Exosomes During Epithelial-mesenchymal Transition and Cancer Progression
  Seminars in Cell & Developmental Biology. Apr, 2015  |   Pubmed ID: 25721809
• The Immune Suppressive Function of Transforming Growth Factor-β (TGF-β) in Human Diseases
  Growth Factors (Chur, Switzerland). Apr, 2015  |   Pubmed ID: 25714613
• Betaglycan Blocks Metastatic Behaviors in Human Granulosa Cell Tumors by Suppressing NFκB-mediated Induction of MMP2
  Cancer Letters. Nov, 2014  |   Pubmed ID: 25128652
• Oncogenic H-ras Reprograms Madin-Darby Canine Kidney (MDCK) Cell-derived Exosomal Proteins Following Epithelial-mesenchymal Transition
  Molecular & Cellular Proteomics : MCP. Aug, 2013  |   Pubmed ID: 23645497
• TCPTP Regulates SFK and STAT3 Signaling and is Lost in Triple-negative Breast Cancers
  Molecular and Cellular Biology. Feb, 2013  |   Pubmed ID: 23166300
• SMAD2, SMAD3 and SMAD4 Mutations in Colorectal Cancer
  Cancer Research. Jan, 2013  |   Pubmed ID: 23139211
• Dynamin II Function is Required for EGF-mediated Stat3 Activation but Not Erk1/2 Phosphorylation
  Growth Factors (Chur, Switzerland). Aug, 2012  |   Pubmed ID: 22574813
• Regulation and Function of Protein Kinases and Phosphatases
  Enzyme Research. 2011  |   Pubmed ID: 22195276
• New Reagents for Improved in Vitro and in Vivo Examination of TGF-β Signalling
  Growth Factors (Chur, Switzerland). Oct, 2011  |   Pubmed ID: 21913800
• Defining the Substrate Specificity Determinants Recognized by the Active Site of C-terminal Src Kinase-homologous Kinase (CHK) and Identification of β-synuclein As a Potential CHK Physiological Substrate
  Biochemistry. Aug, 2011  |   Pubmed ID: 21699177
• Specialized Compartments of Cardiac Nuclei Exhibit Distinct Proteomic Anatomy
  Molecular & Cellular Proteomics : MCP. Jan, 2011  |   Pubmed ID: 20807835
• Proteomics Profiling of Madin-Darby Canine Kidney Plasma Membranes Reveals Wnt-5a Involvement During Oncogenic H-Ras/TGF-beta-mediated Epithelial-mesenchymal Transition
  Molecular & Cellular Proteomics : MCP. Feb, 2011  |   Pubmed ID: 20511395
• Unique Biochemical Properties of the Protein Tyrosine Phosphatase Activity of PTEN-demonstration of Different Active Site Structural Requirements for Phosphopeptide and Phospholipid Phosphatase Activities of PTEN
  Biochimica Et Biophysica Acta. Sep, 2010  |   Pubmed ID: 20685300
• Transforming Growth Factor-beta (TGF-beta) and Brain Tumours
  Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. Aug, 2008  |   Pubmed ID: 18550374
• Expression, Generation, and Purification of Unphosphorylated and Phospho-Ser-380/Thr-382/Thr-383 Form of Recombinant PTEN Phosphatase
  Protein Expression and Purification. Oct, 2007  |   Pubmed ID: 17562371
• PTEN Catalysis of Phospholipid Dephosphorylation Reaction Follows a Two-step Mechanism in Which the Conserved Aspartate-92 Does Not Function As the General Acid--mechanistic Analysis of a Familial Cowden Disease-associated PTEN Mutation
  Cellular Signalling. Jul, 2007  |   Pubmed ID: 17324556
• A Novel Non-catalytic Mechanism Employed by the C-terminal Src-homologous Kinase to Inhibit Src-family Kinase Activity
  The Journal of Biological Chemistry. May, 2004  |   Pubmed ID: 14985335