Howard W. Davidson

Barbara Davis Center for Childhood Diabetes

University of Colorado Anschutz Medical Campus

Howard W. Davidson
Associate Professor of Pediatrics and Immunology/Microbiology

Howard W. Davidson is an Associate Professor at the Barbara Davis Center for Childhood Diabetes on the University of Colorado Anschutz Medical Campus. He received his B.Sc. degree with first class honors from the University of Surrey, and a Ph.D. from the University of Cambridge. Subsequently, he undertook post-doctoral training at the University of Dundee (supervisor Colin Watts) and the Scripps Research Institute (supervisor William Balch), before returning to the University of Cambridge to start his own laboratory, which moved to its current location in 2002.

Dr Davidson’s research initially focused on proteolysis, specifically, studying the enzymes involved in the biosynthesis of insulin in pancreatic beta cells (in his graduate work), and the mechanisms of MHC class II related antigen processing in human B lymphocytes (while a research fellow in Dundee). These interests later broadened to include studies on the biogenesis of endo-lysosomal processing compartments, and more recently, the analysis of humoral and cell-mediated immune responses to human pancreatic beta cells during the development of type 1 diabetes (T1D). Currently his laboratory focuses primarily on developing and validating improved biomarkers and novel immunotherapies for T1D.

Publications

Generazione ad alta efficienza di cellule T Topo primario specifico dell'antigene per test funzionali in un modello di diabete autoimmune

1Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, 2Department of Medicine, Endocrinology, Diabetes & Metabolism, Baylor College of Medicine, 3Scientific Center, Shandong Provincial Hospital affiliated to Shandong University

JoVE 59985

 Immunology and Infection