Howard Crawford

Publications

• Hiding in Plain Sight
  Science (New York, N.Y.). 06, 2019  |   Pubmed ID: 31221844
• Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After Pancreatitis
  Cellular and Molecular Gastroenterology and Hepatology. May, 2019  |   Pubmed ID: 31125624
• ATDC is Required for the Initiation of KRAS-induced Pancreatic Tumorigenesis
  Genes & Development. Jun, 2019  |   Pubmed ID: 31048544
• Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer
  Cell Metabolism. Jun, 2019  |   Pubmed ID: 30827862
• Signaling Networks That Control Cellular Plasticity in Pancreatic Tumorigenesis, Progression, and Metastasis
  Gastroenterology. 05, 2019  |   Pubmed ID: 30716326
• The Loss of ATRX Increases Susceptibility to Pancreatic Injury and Oncogenic KRAS in Female But Not Male Mice
  Cellular and Molecular Gastroenterology and Hepatology. 2019  |   Pubmed ID: 30510993
• Epithelial-Stromal Interactions in Pancreatic Cancer
  Annual Review of Physiology. Feb, 2019  |   Pubmed ID: 30418798
• Spatial and Phenotypic Immune Profiling of Metastatic Colon Cancer
  JCI Insight. 11, 2018  |   Pubmed ID: 30429368
• STAT3 is a Master Regulator of Epithelial Identity and KRAS-driven Tumorigenesis
  Genes & Development. 09, 2018  |   Pubmed ID: 30135074
• HNF1A is a Novel Oncogene That Regulates Human Pancreatic Cancer Stem Cell Properties
  ELife. 08, 2018  |   Pubmed ID: 30074477
• MYC Regulates Ductal-neuroendocrine Lineage Plasticity in Pancreatic Ductal Adenocarcinoma Associated with Poor Outcome and Chemoresistance
  Nature Communications. 11, 2017  |   Pubmed ID: 29170413
• Epithelial-Myeloid Cell Crosstalk Regulates Acinar Cell Plasticity and Pancreatic Remodeling in Mice
  ELife. 10, 2017  |   Pubmed ID: 28980940
• Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis
  Cellular and Molecular Gastroenterology and Hepatology. Jan, 2017  |   Pubmed ID: 28090569
• PDX1 Dynamically Regulates Pancreatic Ductal Adenocarcinoma Initiation and Maintenance
  Genes & Development. 12, 2016  |   Pubmed ID: 28087712
• NRF2 Promotes Tumor Maintenance by Modulating MRNA Translation in Pancreatic Cancer
  Cell. Aug, 2016  |   Pubmed ID: 27477511
• Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions
  Cell Reports. Mar, 2016  |   Pubmed ID: 26947075
• Ablation of Sensory Neurons in a Genetic Model of Pancreatic Ductal Adenocarcinoma Slows Initiation and Progression of Cancer
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2016  |   Pubmed ID: 26929329
• Ductal Pancreatic Cancer Modeling and Drug Screening Using Human Pluripotent Stem Cell- and Patient-derived Tumor Organoids
  Nature Medicine. Nov, 2015  |   Pubmed ID: 26501191
• Oligodendrocyte Regeneration and CNS Remyelination Require TACE/ADAM17
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2015  |   Pubmed ID: 26338334
• Somatostatin Receptor Subtype 2 As Pancreatic Tumorigenesis Suppressor: Identification of a New Targetable Signaling Node
  Gastroenterology. Jun, 2015  |   Pubmed ID: 25921374
• ADAM10 Regulates Notch Function in Intestinal Stem Cells of Mice
  Gastroenterology. Oct, 2014  |   Pubmed ID: 25038433
• Identification and Manipulation of Biliary Metaplasia in Pancreatic Tumors
  Gastroenterology. Jan, 2014  |   Pubmed ID: 23999170
• 뚜렷한 TCR 신호 경로 드라이브 확산 및 Cytokine 생산 T 세포
  Nature Immunology. Feb, 2013  |   Pubmed ID: 23377202
• Constitutive α- and β-secretase Cleavages of the Amyloid Precursor Protein Are Partially Coupled in Neurons, but Not in Frequently Used Cell Lines
  Neurobiology of Disease. Jan, 2013  |   Pubmed ID: 22940630
• ADAM10 is Essential for Notch2-dependent Marginal Zone B Cell Development and CD23 Cleavage in Vivo
  The Journal of Experimental Medicine. Mar, 2010  |   Pubmed ID: 20156974