Hua Lou Department of Genetics and Genome Sciences Case Western Reserve University Biography Publications Institution JoVE Articles Hua Lou has not added a biography. If you are Hua Lou and would like to personalize this page please email our Author Liaison for assistance. Publications A New Bioluminescent Imaging Technology for Studying Oxidative Stress in the Testis and Its Impacts on Fertility Free Radical Biology & Medicine. Aug, 2018 | Pubmed ID: 29803806 Neurofibromatosis Type 1 Alternative Splicing is a Key Regulator of Ras/ERK Signaling and Learning Behaviors in Mice Human Molecular Genetics. 10, 2017 | Pubmed ID: 28934393 Reconstitution of HuR-Inhibited CUGBP1 Expression Protects Cardiomyocytes from Acute Myocardial Infarction-Induced Injury Antioxidants & Redox Signaling. Nov, 2017 | Pubmed ID: 28350193 In Vitro Analysis of Ribonucleoprotein Complex Remodeling and Disassembly Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26965258 Histone Hyperacetylation and Exon Skipping: a Calcium-mediated Dynamic Regulation in Cardiomyocytes Nucleus (Austin, Tex.). 2015 | Pubmed ID: 26325491 A Journey RNA (New York, N.Y.). Apr, 2015 | Pubmed ID: 25780189 Calcium-mediated Histone Modifications Regulate Alternative Splicing in Cardiomyocytes Proceedings of the National Academy of Sciences of the United States of America. Nov, 2014 | Pubmed ID: 25368158 Neurofibromatosis Type 1 Alternative Splicing is a Key Regulator of Ras Signaling in Neurons Molecular and Cellular Biology. Jun, 2014 | Pubmed ID: 24710274 Regulation of Alternative Splicing by Local Histone Modifications: Potential Roles for RNA-guided Mechanisms Nucleic Acids Research. Jan, 2014 | Pubmed ID: 24081581 The P97-UBXD8 Complex Destabilizes MRNA by Promoting Release of Ubiquitinated HuR from MRNP Genes & Development. May, 2013 | Pubmed ID: 23618873 All Three RNA Recognition Motifs and the Hinge Region of HuC Play Distinct Roles in the Regulation of Alternative Splicing Nucleic Acids Research. May, 2013 | Pubmed ID: 23525460 Alternative Splicing of the Neurofibromatosis Type 1 Pre-mRNA is Regulated by the Muscleblind-like Proteins and the CUG-BP and ELAV-like Factors BMC Molecular Biology. Dec, 2012 | Pubmed ID: 23227900 Alternative Splicing of the Neurofibromatosis Type I Pre-mRNA Bioscience Reports. Apr, 2012 | Pubmed ID: 22115364 Depolarization-mediated Regulation of Alternative Splicing Frontiers in Neuroscience. 2011 | Pubmed ID: 22207834 Hu Proteins Regulate Alternative Splicing by Inducing Localized Histone Hyperacetylation in an RNA-dependent Manner Proceedings of the National Academy of Sciences of the United States of America. Sep, 2011 | Pubmed ID: 21808035 RECQL5 is an Important Determinant for Camptothecin Tolerance in Human Colorectal Cancer Cells Bioscience Reports. Oct, 2011 | Pubmed ID: 21210765 Promotion of Exon 6 Inclusion in HuD Pre-mRNA by Hu Protein Family Members Nucleic Acids Research. Jun, 2010 | Pubmed ID: 20159993 The Neurofibromatosis Type I Pre-mRNA is a Novel Target of CELF Protein-mediated Splicing Regulation Nucleic Acids Research. Jan, 2010 | Pubmed ID: 19854948 Repression of Prespliceosome Complex Formation at Two Distinct Steps by Fox-1/Fox-2 Proteins Molecular and Cellular Biology. Sep, 2008 | Pubmed ID: 18573872 Regulation of Neuron-specific Alternative Splicing of Neurofibromatosis Type 1 Pre-mRNA Molecular and Cellular Biology. Feb, 2008 | Pubmed ID: 18086893 Hu Proteins Regulate Polyadenylation by Blocking Sites Containing U-rich Sequences The Journal of Biological Chemistry. Jan, 2007 | Pubmed ID: 17127772 Role for Fox-1/Fox-2 in Mediating the Neuronal Pathway of Calcitonin/calcitonin Gene-related Peptide Alternative RNA Processing Molecular and Cellular Biology. Feb, 2007 | Pubmed ID: 17101796 A Nuclear Function of Hu Proteins As Neuron-specific Alternative RNA Processing Regulators Molecular Biology of the Cell. Dec, 2006 | Pubmed ID: 17035636 Recql5 and Blm RecQ DNA Helicases Have Nonredundant Roles in Suppressing Crossovers Molecular and Cellular Biology. May, 2005 | Pubmed ID: 15831450 U1 SnRNP-dependent Function of TIAR in the Regulation of Alternative RNA Processing of the Human Calcitonin/CGRP Pre-mRNA Molecular and Cellular Biology. Sep, 2003 | Pubmed ID: 12917321 Quantitative Analyse der alternativen Pre-mRNA Spleißen in Maus Gehirn Abschnitten mit RNA In Situ Hybridisierung Assay Xuan Guo1,2, Yiqing Zhao1,3, Hieu Nguyen1, Tonghua Liu2, Zhenghe Wang1,3, Hua Lou1,3,4 1Department of Genetics and Genome Sciences, Case Western Reserve University, 2Department of Endocrinology, Dongfang Hospital of Beijing University of Chinese Medicine, 3Case Comprehensive Cancer Center, Case Western Reserve University, 4Center for RNA Science and Therapeutics, Case Western Reserve University JoVE 57889 Genetics
Quantitative Analyse der alternativen Pre-mRNA Spleißen in Maus Gehirn Abschnitten mit RNA In Situ Hybridisierung Assay Xuan Guo1,2, Yiqing Zhao1,3, Hieu Nguyen1, Tonghua Liu2, Zhenghe Wang1,3, Hua Lou1,3,4 1Department of Genetics and Genome Sciences, Case Western Reserve University, 2Department of Endocrinology, Dongfang Hospital of Beijing University of Chinese Medicine, 3Case Comprehensive Cancer Center, Case Western Reserve University, 4Center for RNA Science and Therapeutics, Case Western Reserve University JoVE 57889 Genetics