Hugues Lortat-Jacob

Publications

• Well-defined Biomimetic Surfaces to Characterize Glycosaminoglycan-mediated Interactions on the Molecular, Supramolecular and Cellular Levels
  Biomaterials. Oct, 2014  |   Pubmed ID: 25088726
• Importance of the Polarity of the Glycosaminoglycan Chain on the Interaction with FGF-1
  Glycobiology. Jul, 2014  |   Pubmed ID: 25015527
• The Effect of Delivering the Chemokine SDF-1α in a Matrix-bound Manner on Myogenesis
  Biomaterials. May, 2014  |   Pubmed ID: 24612919
• Post-Synthetic Regulation of HS Structure: The Yin and Yang of the Sulfs in Cancer
  Frontiers in Oncology. Jan, 2014  |   Pubmed ID: 24459635
• Human Immunodeficiency Virus and Heparan Sulfate: from Attachment to Entry Inhibition
  Frontiers in Immunology. 2013  |   Pubmed ID: 24312095
• The Disulfide Bond Between Cysteine 10 and Cysteine 34 is Required for CCL18 Activity
  Cytokine. Oct, 2013  |   Pubmed ID: 23742785
• Insights into the Mechanism by Which Interferon-γ Basic Amino Acid Clusters Mediate Protein Binding to Heparan Sulfate
  Journal of the American Chemical Society. Jun, 2013  |   Pubmed ID: 23734709
• HSulf Sulfatases Catalyze Processive and Oriented 6-O-desulfation of Heparan Sulfate That Differentially Regulates Fibroblast Growth Factor Activity
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2013  |   Pubmed ID: 23457216
• Toward Libraries of Biotinylated Chondroitin Sulfate Analogues: from Synthesis to in Vivo Studies
  Chemistry (Weinheim an Der Bergstrasse, Germany). Jan, 2013  |   Pubmed ID: 23154924
• Inflammatory Chemokines Direct and Restrict Leukocyte Migration Within Live Tissues As Glycan-bound Gradients
  Current Biology : CB. Dec, 2012  |   Pubmed ID: 23219724
• A New C-Xyloside Induces Modifications of GAG Expression, Structure and Functional Properties
  PloS One. 2012  |   Pubmed ID: 23110134
• Homeostatic and Tissue Reparation Defaults in Mice Carrying Selective Genetic Invalidation of CXCL12/proteoglycan Interactions
  Circulation. Oct, 2012  |   Pubmed ID: 23035208
• Continuous Evolution Profiles for Electronic-tongue-based Analysis
  Angewandte Chemie (International Ed. in English). Oct, 2012  |   Pubmed ID: 22968809
• Factor H and Properdin Recognize Different Epitopes on Renal Tubular Epithelial Heparan Sulfate
  The Journal of Biological Chemistry. Sep, 2012  |   Pubmed ID: 22815489
• Transglutaminase-2 Interaction with Heparin: Identification of a Heparin Binding Site That Regulates Cell Adhesion to Fibronectin-transglutaminase-2 Matrix
  The Journal of Biological Chemistry. May, 2012  |   Pubmed ID: 22442151
• Cell Surface Proteoglycans Syndecan-1 and -4 Bind Overlapping but Distinct Sites in Laminin α3 LG45 Protein Domain
  The Journal of Biological Chemistry. Apr, 2012  |   Pubmed ID: 22351752
• A Synthetic Heparan Sulfate-mimetic Peptide Conjugated to a Mini CD4 Displays Very High Anti- HIV-1 Activity Independently of Coreceptor Usage
  Chemistry & Biology. Jan, 2012  |   Pubmed ID: 22284360
• Semen Clusterin is a Novel DC-SIGN Ligand
  Journal of Immunology (Baltimore, Md. : 1950). Nov, 2011  |   Pubmed ID: 22013110
• Cxcl12 Evolution--subfunctionalization of a Ligand Through Altered Interaction with the Chemokine Receptor
  Development (Cambridge, England). Jul, 2011  |   Pubmed ID: 21693511
• 13C-labeled Heparan Sulfate Analogue As a Tool to Study Protein/heparan Sulfate Interactions by NMR Spectroscopy: Application to the CXCL12α Chemokine
  Journal of the American Chemical Society. Jun, 2011  |   Pubmed ID: 21634378
• Identification of Tubular Heparan Sulfate As a Docking Platform for the Alternative Complement Component Properdin in Proteinuric Renal Disease
  The Journal of Biological Chemistry. Feb, 2011  |   Pubmed ID: 21135110
• Hijacking of the Pleiotropic Cytokine Interferon-γ by the Type III Secretion System of Yersinia Pestis
  PloS One. 2010  |   Pubmed ID: 21179438
• Characterization and Binding Activity of the Chondroitin/dermatan Sulfate Chain from Endocan, a Soluble Endothelial Proteoglycan
  Glycobiology. Nov, 2010  |   Pubmed ID: 20581009
• Cutting Edge: C1q Binds Deoxyribose and Heparan Sulfate Through Neighboring Sites of Its Recognition Domain
  Journal of Immunology (Baltimore, Md. : 1950). Jul, 2010  |   Pubmed ID: 20548024
• Dynamics of Heparan Sulfate Explored by Neutron Scattering
  Physical Chemistry Chemical Physics : PCCP. Apr, 2010  |   Pubmed ID: 20336244
• HABA-based Ionic Liquid Matrices for UV-MALDI-MS Analysis of Heparin and Heparan Sulfate Oligosaccharides
  Glycobiology. Feb, 2010  |   Pubmed ID: 19858171
• A Cell-penetrating Peptide Derived from Human Lactoferrin with Conformation-dependent Uptake Efficiency
  The Journal of Biological Chemistry. Dec, 2009  |   Pubmed ID: 19858187
• The Molecular Basis and Functional Implications of Chemokine Interactions with Heparan Sulphate
  Current Opinion in Structural Biology. Oct, 2009  |   Pubmed ID: 19800217
• A Synthetic CD4-heparan Sulfate Glycoconjugate Inhibits CCR5 and CXCR4 HIV-1 Attachment and Entry
  Nature Chemical Biology. Oct, 2009  |   Pubmed ID: 19734912
• Structure and Functional Relevance of the Slit2 Homodimerization Domain
  EMBO Reports. Jul, 2009  |   Pubmed ID: 19498462
• Heparan Sulfate Proteoglycans Are Receptors for the Cell-surface Trafficking and Biological Activity of Transglutaminase-2
  The Journal of Biological Chemistry. Jul, 2009  |   Pubmed ID: 19398782
• The Signal Peptide of Staphylococcus Aureus Panton Valentine Leukocidin LukS Component Mediates Increased Adhesion to Heparan Sulfates
  PloS One. 2009  |   Pubmed ID: 19347045
• Tyrosine Dephosphorylation of the Syndecan-1 PDZ Binding Domain Regulates Syntenin-1 Recruitment
  The Journal of Biological Chemistry. Apr, 2009  |   Pubmed ID: 19228696
• The Cell Adhesion Molecule "CAR" and Sialic Acid on Human Erythrocytes Influence Adenovirus in Vivo Biodistribution
  PLoS Pathogens. Jan, 2009  |   Pubmed ID: 19119424
• The CXCL12gamma Chemokine Displays Unprecedented Structural and Functional Properties That Make It a Paradigm of Chemoattractant Proteins
  PloS One. 2008  |   Pubmed ID: 18648536
• Direct Peptide Interaction with Surface Glycosaminoglycans Contributes to the Cell Penetration of Maurocalcine
  The Journal of Biological Chemistry. Aug, 2008  |   Pubmed ID: 18603532
• The HIV-1 Envelope Glycoprotein Gp120 Features Four Heparan Sulfate Binding Domains, Including the Co-receptor Binding Site
  The Journal of Biological Chemistry. May, 2008  |   Pubmed ID: 18378683
• Polypyrrole Oligosaccharide Array and Surface Plasmon Resonance Imaging for the Measurement of Glycosaminoglycan Binding Interactions
  Analytical Chemistry. May, 2008  |   Pubmed ID: 18348577
• Relationships Between Glycosaminoglycan and Receptor Binding Sites in Chemokines-the CXCL12 Example
  Carbohydrate Research. Aug, 2008  |   Pubmed ID: 18334249
• Efficient Long-term and High-yielded Production of a Recombinant Proteoglycan in Eukaryotic HEK293 Cells Using a Membrane-based Bioreactor
  Biochemical and Biophysical Research Communications. May, 2008  |   Pubmed ID: 18261977
• Adenovirus Dodecahedron Cell Attachment and Entry Are Mediated by Heparan Sulfate and Integrins and Vary Along the Cell Cycle
  Virology. Feb, 2008  |   Pubmed ID: 17950396
• The Novel CXCL12gamma Isoform Encodes an Unstructured Cationic Domain Which Regulates Bioactivity and Interaction with Both Glycosaminoglycans and CXCR4
  PloS One. 2007  |   Pubmed ID: 17971873
• Structural View of Glycosaminoglycan-protein Interactions
  Carbohydrate Research. Feb, 2007  |   Pubmed ID: 17229412
• Organization of Human Interferon Gamma-heparin Complexes from Solution Properties and Hydrodynamics
  Biochemistry. Nov, 2006  |   Pubmed ID: 17073444
• Structural and Mutational Analysis of Human Ad37 and Canine Adenovirus 2 Fiber Heads in Complex with the D1 Domain of Coxsackie and Adenovirus Receptor
  The Journal of Biological Chemistry. Nov, 2006  |   Pubmed ID: 16923808
• Mannose Hyperbranched Dendritic Polymers Interact with Clustered Organization of DC-SIGN and Inhibit Gp120 Binding
  FEBS Letters. May, 2006  |   Pubmed ID: 16616922
• Heparan Sulphate Proteoglycans and Viral Vectors : Ally or Foe?
  Current Gene Therapy. Feb, 2006  |   Pubmed ID: 16475944
• Heparan Sulfate Mimicry: a Synthetic Glycoconjugate That Recognizes the Heparin Binding Domain of Interferon-gamma Inhibits the Cytokine Activity
  The Journal of Biological Chemistry. Nov, 2005  |   Pubmed ID: 16155294
• The Fucose-binding Lectin from Ralstonia Solanacearum. A New Type of Beta-propeller Architecture Formed by Oligomerization and Interacting with Fucoside, Fucosyllactose, and Plant Xyloglucan
  The Journal of Biological Chemistry. Jul, 2005  |   Pubmed ID: 15923179
• Heparan Sulfate Targets the HIV-1 Envelope Glycoprotein Gp120 Coreceptor Binding Site
  The Journal of Biological Chemistry. Jun, 2005  |   Pubmed ID: 15797855
• Glycosaminoglycans and Protein Disulfide Isomerase-mediated Reduction of HIV Env
  Molecular Pharmacology. Apr, 2005  |   Pubmed ID: 15644496
• A Novel Strategy for Defining Critical Amino Acid Residues Involved in Protein/glycosaminoglycan Interactions
  The Journal of Biological Chemistry. Dec, 2004  |   Pubmed ID: 15485868
• Synthesis of Tailor-made Glycoconjugate Mimetics of Heparan Sulfate That Bind IFN-gamma in the Nanomolar Range
  Chemistry (Weinheim an Der Bergstrasse, Germany). Sep, 2004  |   Pubmed ID: 15352109
• Heparan Sulfate/heparin Oligosaccharides Protect Stromal Cell-derived Factor-1 (SDF-1)/CXCL12 Against Proteolysis Induced by CD26/dipeptidyl Peptidase IV
  The Journal of Biological Chemistry. Oct, 2004  |   Pubmed ID: 15292258
• NMR Characterization of the Interaction Between the C-terminal Domain of Interferon-gamma and Heparin-derived Oligosaccharides
  The Biochemical Journal. Nov, 2004  |   Pubmed ID: 15270718
• Heparan Sulfate Proteoglycan Mediates the Selective Attachment and Internalization of Serotype 3 Human Adenovirus Dodecahedron
  Virology. Apr, 2004  |   Pubmed ID: 15051392
• Characterization of Endostatin Binding to Heparin and Heparan Sulfate by Surface Plasmon Resonance and Molecular Modeling: Role of Divalent Cations
  The Journal of Biological Chemistry. Jan, 2004  |   Pubmed ID: 14585835
• Normal Human Keratinocytes Bind to the Alpha3LG4/5 Domain of Unprocessed Laminin-5 Through the Receptor Syndecan-1
  The Journal of Biological Chemistry. Nov, 2003  |   Pubmed ID: 12947106
• DC-SIGN and L-SIGN Are High Affinity Binding Receptors for Hepatitis C Virus Glycoprotein E2
  The Journal of Biological Chemistry. May, 2003  |   Pubmed ID: 12609975
• A Kinetics and Modeling Study of RANTES(9-68) Binding to Heparin Reveals a Mechanism of Cooperative Oligomerization
  Biochemistry. Dec, 2002  |   Pubmed ID: 12475226
• Adenovirus Protein Involved in Virus Internalization Recruits Ubiquitin-protein Ligases
  Biochemistry. Dec, 2002  |   Pubmed ID: 12450395
• Human Cytomegalovirus Binding to DC-SIGN is Required for Dendritic Cell Infection and Target Cell Trans-infection
  Immunity. Nov, 2002  |   Pubmed ID: 12433371
• Heparin-aggregated RANTES Can Be Crystallised
  Acta Crystallographica. Section D, Biological Crystallography. Oct, 2002  |   Pubmed ID: 12351884
• Cellular Glycosaminoglycans and Low Density Lipoprotein Receptor Are Involved in Hepatitis C Virus Adsorption
  Journal of Medical Virology. Oct, 2002  |   Pubmed ID: 12210409
• Cell Membrane GM1 Ganglioside is a Functional Coreceptor for Fibroblast Growth Factor 2
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2002  |   Pubmed ID: 11917140
• Heparan Sulfate-mediated Binding of Infectious Dengue Virus Type 2 and Yellow Fever Virus
  Virology. Jan, 2002  |   Pubmed ID: 11878919
• Structural Diversity of Heparan Sulfate Binding Domains in Chemokines
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2002  |   Pubmed ID: 11830659
• Sulfated Polysaccharides Increase Plasma Levels of SDF-1 in Monkeys and Mice: Involvement in Mobilization of Stem/progenitor Cells
  Blood. Jan, 2002  |   Pubmed ID: 11756151