Ian J. Jackson

Publications

• A Dominant-Negative Mutation of Mouse Lmx1b Causes Glaucoma and Is Semi-lethal Via LBD1-Mediated Dimerisation
  PLoS Genetics. May, 2014  |   Pubmed ID: 24809698
• A Novel Mouse Model of Warburg Micro Syndrome Reveals Roles for RAB18 in Eye Development and Organisation of the Neuronal Cytoskeleton
  Disease Models & Mechanisms. Apr, 2014  |   Pubmed ID: 24764192
• Kdm3a Lysine Demethylase is an Hsp90 Client Required for Cytoskeletal Rearrangements During Spermatogenesis
  Molecular Biology of the Cell. Apr, 2014  |   Pubmed ID: 24554764
• A Conditional Zebrafish MITF Mutation Reveals MITF Levels Are Critical for Melanoma Promotion Vs. Regression in Vivo
  The Journal of Investigative Dermatology. Jan, 2014  |   Pubmed ID: 23831555
• Acute Versus Chronic Loss of Mammalian Azi1/Cep131 Results in Distinct Ciliary Phenotypes
  PLoS Genetics. Dec, 2013  |   Pubmed ID: 24415959
• A Trans-acting Protein Effect Causes Severe Eye Malformation in the Mp Mouse
  PLoS Genetics. Dec, 2013  |   Pubmed ID: 24348270
• How the Leopard Gets Its Spots: a Transmembrane Peptidase Specifies Feline Pigmentation Patterns
  Pigment Cell & Melanoma Research. Jul, 2013  |   Pubmed ID: 23923821
• A Comparative Phenotypic and Genomic Analysis of C57BL/6J and C57BL/6N Mouse Strains
  Genome Biology. Jul, 2013  |   Pubmed ID: 23902802
• Signatures of Diversifying Selection in European Pig Breeds
  PLoS Genetics. Apr, 2013  |   Pubmed ID: 23637623
• A CNS-specific Hypomorphic Pdgfr-beta Mutant Model of Diabetic Retinopathy
  Investigative Ophthalmology & Visual Science. May, 2013  |   Pubmed ID: 23633653
• Mutation Spectrum in RAB3GAP1, RAB3GAP2, and RAB18 and Genotype-phenotype Correlations in Warburg Micro Syndrome and Martsolf Syndrome
  Human Mutation. May, 2013  |   Pubmed ID: 23420520
• Germline Melanocortin-1-receptor Genotype is Associated with Severity of Cutaneous Phenotype in Congenital Melanocytic Nevi: a Role for MC1R in Human Fetal Development
  The Journal of Investigative Dermatology. Aug, 2012  |   Pubmed ID: 22572819
• P-Rex1 is Required for Efficient Melanoblast Migration and Melanoma Metastasis
  Nature Communications. 2011  |   Pubmed ID: 22109529
• Rac1 Drives Melanoblast Organization During Mouse Development by Orchestrating Pseudopod- Driven Motility and Cell-cycle Progression
  Developmental Cell. Oct, 2011  |   Pubmed ID: 21924960
• Mouse Genomic Variation and Its Effect on Phenotypes and Gene Regulation
  Nature. Sep, 2011  |   Pubmed ID: 21921910
• Differentiated Melanocyte Cell Division Occurs in Vivo and is Promoted by Mutations in Mitf
  Development (Cambridge, England). Aug, 2011  |   Pubmed ID: 21771814
• Loss of the BMP Antagonist, SMOC-1, Causes Ophthalmo-acromelic (Waardenburg Anophthalmia) Syndrome in Humans and Mice
  PLoS Genetics. Jul, 2011  |   Pubmed ID: 21750680
• Human and Mouse Mutations in WDR35 Cause Short-rib Polydactyly Syndromes Due to Abnormal Ciliogenesis
  American Journal of Human Genetics. Apr, 2011  |   Pubmed ID: 21473986
• A Zebrafish Model for Nevus Regeneration
  Pigment Cell & Melanoma Research. Apr, 2011  |   Pubmed ID: 21324102
• The Opdc Missense Mutation of Pax2 Has a Milder Than Loss-of-function Phenotype
  Human Molecular Genetics. Jan, 2011  |   Pubmed ID: 20943750
• In Praise of Books
  Pigment Cell & Melanoma Research. Nov, 2010  |   Pubmed ID: 21129162
• Involvement of the Melanocortin-1 Receptor in Acute Pain and Pain of Inflammatory but Not Neuropathic Origin
  PloS One. 2010  |   Pubmed ID: 20856883
• The Physiological and Phenotypic Determinants of Human Tanning Measured As Change in Skin Colour Following a Single Dose of Ultraviolet B Radiation
  Experimental Dermatology. Jul, 2010  |   Pubmed ID: 20648713
• Human Beta-defensin 3 Has Immunosuppressive Activity in Vitro and in Vivo
  European Journal of Immunology. Apr, 2010  |   Pubmed ID: 20104491
• Ex Vivo Live Imaging of Melanoblast Migration in Embryonic Mouse Skin
  Pigment Cell & Melanoma Research. Apr, 2010  |   Pubmed ID: 20067551
• Col4a1 Mutation in Mice Causes Defects in Vascular Function and Low Blood Pressure Associated with Reduced Red Blood Cell Volume
  Human Molecular Genetics. Mar, 2010  |   Pubmed ID: 20056676
• GABAergic Amacrine Cells and Visual Function Are Reduced in PAC1 Transgenic Mice
  Neuropharmacology. Jan, 2010  |   Pubmed ID: 19596361
• Genetic Determinants of Hair and Eye Colours in the Scottish and Danish Populations
  BMC Genetics. 2009  |   Pubmed ID: 20042077
• Palmitoylation Regulates Epidermal Homeostasis and Hair Follicle Differentiation
  PLoS Genetics. Nov, 2009  |   Pubmed ID: 19956733
• Mc1r Pathway Regulation of Zebrafish Melanosome Dispersion
  Zebrafish. Dec, 2008  |   Pubmed ID: 19133827
• Expression of the Fras1/frem Gene Family During Zebrafish Development and Fin Morphogenesis
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Nov, 2008  |   Pubmed ID: 18816440
• Diphthamide Modification of EEF2 Requires a J-domain Protein and is Essential for Normal Development
  Journal of Cell Science. Oct, 2008  |   Pubmed ID: 18765564
• Genetics. Beta-defensin Repertoire Expands
  Science (New York, N.Y.). Nov, 2007  |   Pubmed ID: 18048676
• Humanized MC1R Transgenic Mice Reveal Human Specific Receptor Function
  Human Molecular Genetics. Oct, 2007  |   Pubmed ID: 17652101
• Genomic Localization of a Dct-LacZ Transgene Locus: a Simple Assay for Transgene Status
  Pigment Cell Research / Sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society. Dec, 2006  |   Pubmed ID: 17083491
• Cardiac Malformations and Midline Skeletal Defects in Mice Lacking Filamin A
  Human Molecular Genetics. Aug, 2006  |   Pubmed ID: 16825286
• Identifying the Genes Causing Human Diversity
  European Journal of Human Genetics : EJHG. Sep, 2006  |   Pubmed ID: 16723996
• Regulation of Pigmentation in Zebrafish Melanophores
  Pigment Cell Research / Sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society. Jun, 2006  |   Pubmed ID: 16704454
• Genomic Anatomy of the Tyrp1 (brown) Deletion Complex
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2006  |   Pubmed ID: 16505357
• Dominant Mutations of Col4a1 Result in Basement Membrane Defects Which Lead to Anterior Segment Dysgenesis and Glomerulopathy
  Human Molecular Genetics. Nov, 2005  |   Pubmed ID: 16159887
• Genotype-phenotype Correlation of Mouse Pde6b Mutations
  Investigative Ophthalmology & Visual Science. Sep, 2005  |   Pubmed ID: 16123450
• Wa5 is a Novel ENU-induced Antimorphic Allele of the Epidermal Growth Factor Receptor
  Mammalian Genome : Official Journal of the International Mammalian Genome Society. Jul, 2004  |   Pubmed ID: 15366372
• 17th International Mouse Genome Conference
  Mammalian Genome : Official Journal of the International Mammalian Genome Society. Jul, 2004  |   Pubmed ID: 15366370
• The Extracellular Matrix Gene Frem1 is Essential for the Normal Adhesion of the Embryonic Epidermis
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2004  |   Pubmed ID: 15345741
• The G-netics of Dark Skin
  Nature Genetics. Sep, 2004  |   Pubmed ID: 15340429
• Large-scale Analysis of Gene Structure in Rhodopsin-like GPCRs: Evidence for Widespread Loss of an Ancient Intron
  Gene. Aug, 2004  |   Pubmed ID: 15302402
• Haploinsufficiency for Phox2b in Mice Causes Dilated Pupils and Atrophy of the Ciliary Ganglion: Mechanistic Insights into Human Congenital Central Hypoventilation Syndrome
  Human Molecular Genetics. Jul, 2004  |   Pubmed ID: 15150159
• Widespread Tangential Dispersion and Extensive Cell Death During Early Neurogenesis in the Mouse Neocortex
  Developmental Biology. Mar, 2004  |   Pubmed ID: 14975720
• Sequence Characterization of Teleost Fish Melanocortin Receptors
  Annals of the New York Academy of Sciences. Jun, 2003  |   Pubmed ID: 12851332
• The Structure and Evolution of the Melanocortin and MCH Receptors in Fish and Mammals
  Genomics. Feb, 2003  |   Pubmed ID: 12620396
• The Promises and Problems of Linkage Analysis by Using the Current Canine Genome Map
  Mammalian Genome : Official Journal of the International Mammalian Genome Society. Nov, 2002  |   Pubmed ID: 12461654
• Neural Crest Progenitors of the Melanocyte Lineage: Coat Colour Patterns Revisited
  Development (Cambridge, England). Jul, 2002  |   Pubmed ID: 12091305
• Bcl2 Regulation by the Melanocyte Master Regulator Mitf Modulates Lineage Survival and Melanoma Cell Viability
  Cell. Jun, 2002  |   Pubmed ID: 12086670
• Presence of Visual Head Tracking Differentiates Normal Sighted from Retinal Degenerate Mice
  Neuroscience Letters. May, 2002  |   Pubmed ID: 12023058
• Dominant Role of the Niche in Melanocyte Stem-cell Fate Determination
  Nature. Apr, 2002  |   Pubmed ID: 11976685
• Novel ENU-induced Eye Mutations in the Mouse: Models for Human Eye Disease
  Human Molecular Genetics. Apr, 2002  |   Pubmed ID: 11929848