Ibra S. Fancher
Research Assistant Professor
Ibra Fancher is a Research Assistant Professor in the Department of Medicine, Division of Pulmonary, Critical Care, Sleep and Allergy at the University of Illinois at Chicago in Chicago, Illinois. He received his undergraduate degree from Saint Vincent College in Latrobe, PA and his Ph.D. from West Virginia University in Morgantown, WV.
Dr. Fancher’s research includes extensive study of vascular K+ ion channels in smooth muscle and endothelial cells. As a post-doctoral fellow in the laboratories of Irena Levitan and Shane Phillips, Dr. Fancher established a critical role for endothelial inwardly rectifying K+ (Kir) channels in regulating flow-mediated vasodilation. He also found that hypercholesterolemia promotes endothelial dysfunction through cholesterol-induced suppression of Kir channel function. His ongoing work aims to investigate the effects of a variety of cardiovascular risk factors on Kir channel function, including hypertension and obesity. Dr. Fancher has generated novel genetic mouse models as an approach to investigate the overarching questions, including a mutant mouse that contains a cholesterol-insensitive Kir channel.
Dr. Fancher received a Post-Doctoral American Heart Association Fellowship Award in 2016 and was promoted to Research Assistant Professor in the laboratory of Irena Levitan in April, 2019. He continues to use a mix of in vitro and in vivo models to answer key questions regarding the regulation of vascular tone by ion channels to ultimately determine how these processes are affected by and contribute to cardiovascular disease.