Imo E. Hoefer Department of Experimental Cardiology University Medical Center Utrecht Biography Publications Institution JoVE Articles Imo E. Hoefer has not added a biography. If you are Imo E. Hoefer and would like to personalize this page please email our Author Liaison for assistance. Publications Monocyte Hyporesponsiveness and Toll-like Receptor Expression Profiles in Coronary Artery Bypass Grafting and Its Clinical Implications for Postoperative Inflammatory Response and Pneumonia: An Observational Cohort Study European Journal of Anaesthesiology. Nov, 2014 | Pubmed ID: 25405275 Intracoronary Infusion of Encapsulated Glucagon-like Peptide-1-eluting Mesenchymal Stem Cells Preserves Left Ventricular Function in a Porcine Model of Acute Myocardial Infarction Circulation. Cardiovascular Interventions. Oct, 2014 | Pubmed ID: 25294400 Popliteal Artery Aneurysms Differ from Abdominal Aortic Aneurysms in Cellular Topography and Inflammatory Markers Journal of Vascular Surgery. Oct, 2014 | Pubmed ID: 25282691 Biomechanical Factors in Atherosclerosis: Mechanisms and Clinical Implications† European Heart Journal. Nov, 2014 | Pubmed ID: 25230814 Extracellular Vesicle Protein CD14 Relates to Common Carotid Intima-media Thickness in Eight Year Old Children Atherosclerosis. Oct, 2014 | Pubmed ID: 25108076 Endogenous Contrast MRI of Cardiac Fibrosis: Beyond Late Gadolinium Enhancement Journal of Magnetic Resonance Imaging : JMRI. Aug, 2014 | Pubmed ID: 25091144 Atherosclerotic Risk Factors and Atherosclerotic Postoperative Events Are Associated with Low Inflammation in Abdominal Aortic Aneurysms Atherosclerosis. Aug, 2014 | Pubmed ID: 24972144 The CD200-CD200 Receptor Inhibitory Axis Controls Arteriogenesis and Local T Lymphocyte Influx PloS One. 2014 | Pubmed ID: 24897500 The Multifaceted Functions of CXCL10 in Cardiovascular Disease BioMed Research International. 2014 | Pubmed ID: 24868552 Admittance-based Pressure-volume Loops Versus Gold Standard Cardiac Magnetic Resonance Imaging in a Porcine Model of Myocardial Infarction Physiological Reports. 2014 | Pubmed ID: 24771693 Six-month Healing of the Nonocclusive Coronary Anastomotic Connector in an Off-pump Porcine Bypass Model Innovations (Philadelphia, Pa.). Mar-Apr, 2014 | Pubmed ID: 24758949 Circulating Immunoglobulins Are Not Associated with Intraplaque Mast Cell Number and Other Vulnerable Plaque Characteristics in Patients with Carotid Artery Stenosis PloS One. 2014 | Pubmed ID: 24586471 Leukotriene B4 Levels in Human Atherosclerotic Plaques and Abdominal Aortic Aneurysms PloS One. 2014 | Pubmed ID: 24475136 Absence of Chemokine (C-x-C Motif) Ligand 10 Diminishes Perfusion Recovery After Local Arterial Occlusion in Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2014 | Pubmed ID: 24407030 FLow-induced PRotrusions (FLIPRs): a Platelet-derived Platform for the Retrieval of Microparticles by Monocytes and Neutrophils Circulation Research. Feb, 2014 | Pubmed ID: 24406984 Innate Collateral Segments Are Predominantly Present in the Subendocardium Without Preferential Connectivity Within the Left Ventricular Wall The Journal of Physiology. Mar, 2014 | Pubmed ID: 24366260 Toll-like Receptor 4 Inhibitor TAK-242 Treatment Does Not Influence Perfusion Recovery in Tissue Ischemia Journal of Cardiovascular Pharmacology. Jan, 2014 | Pubmed ID: 24084220 The Nonocclusive Laser-assisted Coronary Anastomotic Connector in an Off-pump Porcine Bypass Model The Journal of Thoracic and Cardiovascular Surgery. Apr, 2014 | Pubmed ID: 23993317 Soluble ST2 Levels Are Not Associated with Secondary Cardiovascular Events and Vulnerable Plaque Phenotype in Patients with Carotid Artery Stenosis Atherosclerosis. Nov, 2013 | Pubmed ID: 24125409 Circulating Cells As Predictors of Secondary Manifestations of Cardiovascular Disease: Design of the CIRCULATING CELLS Study Clinical Research in Cardiology : Official Journal of the German Cardiac Society. Nov, 2013 | Pubmed ID: 23975238 Mast Cells in Human Carotid Atherosclerotic Plaques Are Associated with Intraplaque Microvessel Density and the Occurrence of Future Cardiovascular Events European Heart Journal. Jun, 2013 | Pubmed ID: 23756333 Proteomics of Plaques and Novel Sources of Potential Biomarkers for Atherosclerosis Proteomics. Clinical Applications. Aug, 2013 | Pubmed ID: 23670906 Circulating Biomarkers for Predicting Cardiovascular Disease Risk; a Systematic Review and Comprehensive Overview of Meta-analyses PloS One. 2013 | Pubmed ID: 23630624 Biomechanical Factors As Triggers of Vascular Growth Cardiovascular Research. Jul, 2013 | Pubmed ID: 23580605 Toll-Like Receptor Induced CD11b and L-selectin Response in Patients with Coronary Artery Disease PloS One. 2013 | Pubmed ID: 23573259 CD26 Inhibition Enhances Perfusion Recovery in ApoE-/-mice Current Vascular Pharmacology. Jan, 2013 | Pubmed ID: 23391419 Distinct CD44 Splice Variants Differentially Affect Collateral Artery Growth Current Vascular Pharmacology. Jan, 2013 | Pubmed ID: 23391418 Temporal Changes of Soluble ST2 After Cardiovascular Interventions European Journal of Clinical Investigation. Feb, 2013 | Pubmed ID: 23215810 Fractional Flow Reserve is Not Associated with Inflammatory Markers in Patients with Stable Coronary Artery Disease PloS One. 2012 | Pubmed ID: 23091596 Deep Proteome Profiling of Circulating Granulocytes Reveals Bactericidal/permeability-increasing Protein As a Biomarker for Severe Atherosclerotic Coronary Stenosis Journal of Proteome Research. Nov, 2012 | Pubmed ID: 23020738 Transendocardial Cell Injection is Not Superior to Intracoronary Infusion in a Porcine Model of Ischaemic Cardiomyopathy: a Study on Delivery Efficiency Journal of Cellular and Molecular Medicine. Nov, 2012 | Pubmed ID: 22697212 Shear Induced Collateral Artery Growth Modulated by Endoglin but Not by ALK1 Journal of Cellular and Molecular Medicine. Oct, 2012 | Pubmed ID: 22436015 A Fibronectin-fibrinogen-tropoelastin Coating Reduces Smooth Muscle Cell Growth but Improves Endothelial Cell Function Journal of Cellular and Molecular Medicine. Sep, 2012 | Pubmed ID: 22225866 Inducible Cardiac Ischaemia is Related to a Decrease in the Whole-blood Toll-like Receptor 2 and 4 Response Clinical Science (London, England : 1979). Jun, 2012 | Pubmed ID: 22188581 Circumferential Heterogeneity in the Abdominal Aortic Aneurysm Wall Composition Suggests Lateral Sides to Be More Rupture Prone Journal of Vascular Surgery. Jan, 2012 | Pubmed ID: 21944916 Quantification of Collateral Artery Growth by Automated Fluorescent Microsphere Perfusion International Journal of Cardiology. Nov, 2012 | Pubmed ID: 21601932 In-vivo Validation of a New Non-invasive Continuous Ventricular Stroke Volume Monitoring System in an Animal Model Critical Care (London, England). 2011 | Pubmed ID: 21745380 Forkhead Box Protein P1 As a Downstream Target of Transforming Growth Factor-β Induces Collagen Synthesis and Correlates with a More Stable Plaque Phenotype Atherosclerosis. Sep, 2011 | Pubmed ID: 21683954 Toll-like Receptor 2 and 4 Stimulation Elicits an Enhanced Inflammatory Response in Human Obese Patients with Atherosclerosis Clinical Science (London, England : 1979). Sep, 2011 | Pubmed ID: 21446916 Human Mesenchymal Stem Cell-conditioned Medium Improves Cardiac Function Following Myocardial Infarction Stem Cell Research. May, 2011 | Pubmed ID: 21419744 Lack of Fibronectin-EDA Promotes Survival and Prevents Adverse Remodeling and Heart Function Deterioration After Myocardial Infarction Circulation Research. Mar, 2011 | Pubmed ID: 21350212 Toll-like Receptor 4 is Involved in Human and Mouse Vein Graft Remodeling, and Local Gene Silencing Reduces Vein Graft Disease in Hypercholesterolemic APOE*3Leiden Mice Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2011 | Pubmed ID: 21330606 Arterial Occlusion Induces Systemic Changes in Leucocyte Composition European Journal of Clinical Investigation. Sep, 2011 | Pubmed ID: 21314827 Assessment of Collateral Artery Function and Growth in a Pig Model of Stepwise Coronary Occlusion American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2011 | Pubmed ID: 20952668 Arteriogenesis Requires Toll-like Receptor 2 and 4 Expression in Bone-marrow Derived Cells Journal of Molecular and Cellular Cardiology. Jan, 2011 | Pubmed ID: 20708624 Blocking Interferon {beta} Stimulates Vascular Smooth Muscle Cell Proliferation and Arteriogenesis The Journal of Biological Chemistry. Nov, 2010 | Pubmed ID: 20736166 Hyaluronic Acid Metabolism is Increased in Unstable Plaques European Journal of Clinical Investigation. Sep, 2010 | Pubmed ID: 20597964 Targeted Deletion of the Inhibitory NF-kappaB P50 Subunit in Bone Marrow-derived Cells Improves Collateral Growth After Arterial Occlusion Cardiovascular Research. Oct, 2010 | Pubmed ID: 20495189 Myocardial Ischemia/reperfusion Injury is Mediated by Leukocytic Toll-like Receptor-2 and Reduced by Systemic Administration of a Novel Anti-toll-like Receptor-2 Antibody Circulation. Jan, 2010 | Pubmed ID: 20026776 Impaired Recruitment of HHT-1 Mononuclear Cells to the Ischaemic Heart is Due to an Altered CXCR4/CD26 Balance Cardiovascular Research. Feb, 2010 | Pubmed ID: 19762327 Local Cytokine Concentrations and Oxygen Pressure Are Related to Maturation of the Collateral Circulation in Humans Journal of the American College of Cardiology. Jun, 2009 | Pubmed ID: 19497439 Locally Applied Recombinant Plasmin Results in Effective Thrombolysis in a Porcine Model of Arteriovenous Graft Thrombosis Journal of Vascular and Interventional Radiology : JVIR. Jul, 2009 | Pubmed ID: 19481472 Endothelial Glycocalyx Dimensions Are Reduced in Growing Collateral Arteries and Modulate Leucocyte Adhesion in Arteriogenesis Journal of Cellular and Molecular Medicine. Sep, 2009 | Pubmed ID: 19438808 Exenatide Reduces Infarct Size and Improves Cardiac Function in a Porcine Model of Ischemia and Reperfusion Injury Journal of the American College of Cardiology. Feb, 2009 | Pubmed ID: 19195607 Targeted Deletion of Nuclear Factor KappaB P50 Enhances Cardiac Remodeling and Dysfunction Following Myocardial Infarction Circulation Research. Mar, 2009 | Pubmed ID: 19168865 Biobanks and the Search for Predictive Biomarkers of Local and Systemic Outcome in Atherosclerotic Disease Thrombosis and Haemostasis. Jan, 2009 | Pubmed ID: 19132188 Increased Expression of the Transforming Growth Factor-beta Signaling Pathway, Endoglin, and Early Growth Response-1 in Stable Plaques Stroke; a Journal of Cerebral Circulation. Feb, 2009 | Pubmed ID: 19074480 The Proteoglycan Osteoglycin/mimecan is Correlated with Arteriogenesis Molecular and Cellular Biochemistry. Feb, 2009 | Pubmed ID: 18979232 Toll-like Receptor 2 and 4 Response and Expression on Monocytes Decrease Rapidly in Patients Undergoing Arterial Surgery and Are Related to Preoperative Smoking Shock (Augusta, Ga.). Jan, 2009 | Pubmed ID: 18650783 The Nuclear Factor-kappa B P50 Subunit is Involved in Flow-induced Outward Arterial Remodeling Atherosclerosis. Feb, 2009 | Pubmed ID: 18617174 Past, Current and Future Concepts in Atherosclerotic Biobanking Future Cardiology. Nov, 2008 | Pubmed ID: 19804357 Targeting Adhesion Molecules in Cardiovascular Disorders Cardiovascular & Hematological Disorders Drug Targets. Dec, 2008 | Pubmed ID: 19075635 Endothelial Progenitor Cell Levels in Obese Men with the Metabolic Syndrome and the Effect of Simvastatin Monotherapy Vs. Simvastatin/ezetimibe Combination Therapy European Heart Journal. Nov, 2008 | Pubmed ID: 18824462 Insights into Mechanisms Behind Arteriogenesis: What Does the Future Hold? Journal of Leukocyte Biology. Dec, 2008 | Pubmed ID: 18678607 Interferon-beta Signaling is Enhanced in Patients with Insufficient Coronary Collateral Artery Development and Inhibits Arteriogenesis in Mice Circulation Research. May, 2008 | Pubmed ID: 18420941 Hyaluronic Acid: Targeting Immune Modulatory Components of the Extracellular Matrix in Atherosclerosis Current Medicinal Chemistry. 2008 | Pubmed ID: 18393848 Toll-like Receptor 4 Mediates Maladaptive Left Ventricular Remodeling and Impairs Cardiac Function After Myocardial Infarction Circulation Research. Feb, 2008 | Pubmed ID: 18007026 Reduction of Myocardial Infarct Size by Human Mesenchymal Stem Cell Conditioned Medium Stem Cell Research. Nov, 2007 | Pubmed ID: 19383393 Something is Rotten in the State of Angiogenesis -- H2S As Gaseous Stimulator of Angiogenesis Cardiovascular Research. Oct, 2007 | Pubmed ID: 17706951 A New Intra-arterial Delivery Platform for Pro-arteriogenic Compounds to Stimulate Collateral Artery Growth Via Transforming Growth Factor-beta1 Release Journal of the American College of Cardiology. Jul, 2007 | Pubmed ID: 17659203 Growth Factor Therapy in Atherosclerotic Disease-friend or Foe Current Pharmaceutical Design. 2007 | Pubmed ID: 17584109 Haematopoietic and Endothelial Progenitor Cells Are Deficient in Quiescent Systemic Lupus Erythematosus Annals of the Rheumatic Diseases. Jul, 2007 | Pubmed ID: 17329307 End-stage Renal Disease Causes an Imbalance Between Endothelial and Smooth Muscle Progenitor Cells American Journal of Physiology. Renal Physiology. Apr, 2007 | Pubmed ID: 17200161 Arteriogenesis Depends on Circulating Monocytes and Macrophage Accumulation and is Severely Depressed in Op/op Mice Journal of Leukocyte Biology. Jul, 2006 | Pubmed ID: 16684892 Pharmaceutical Interventions to Influence Arteriogenesis: New Concepts to Treat Ischemic Heart Disease Current Medicinal Chemistry. 2006 | Pubmed ID: 16611079 G-CSF Administration After Myocardial Infarction in Mice Attenuates Late Ischemic Cardiomyopathy by Enhanced Arteriogenesis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2006 | Pubmed ID: 16571777 Experimental Models of Arteriogenesis: Differences and Implications Lab Animal. Feb, 2006 | Pubmed ID: 16446736 Aspirin, but Not Clopidogrel, Reduces Collateral Conductance in a Rabbit Model of Femoral Artery Occlusion Journal of the American College of Cardiology. Sep, 2005 | Pubmed ID: 16168281 Leukocyte Subpopulations and Arteriogenesis: Specific Role of Monocytes, Lymphocytes and Granulocytes Atherosclerosis. Aug, 2005 | Pubmed ID: 16039282 Abnormal Monocyte Recruitment and Collateral Artery Formation in Monocyte Chemoattractant Protein-1 Deficient Mice Vascular Medicine (London, England). Nov, 2004 | Pubmed ID: 15678621 All Arteriogenesis is Local? Home Boys Versus the Newcomers Circulation Research. Nov, 2004 | Pubmed ID: 15539637 Differential Effects of MCP-1 and Leptin on Collateral Flow and Arteriogenesis Cardiovascular Research. Nov, 2004 | Pubmed ID: 15485696 Arteriogenesis Proceeds Via ICAM-1/Mac-1- Mediated Mechanisms Circulation Research. May, 2004 | Pubmed ID: 15059933 Invasive and Non-invasive Evaluation of Spontaneous Arteriogenesis in a Novel Porcine Model for Peripheral Arterial Obstructive Disease Atherosclerosis. Mar, 2003 | Pubmed ID: 12618266 Involvement of the Fibroblast Growth Factor System in Adaptive and Chemokine-induced Arteriogenesis Circulation Research. Mar, 2003 | Pubmed ID: 12600883 Modulation of Collateral Artery Growth in a Porcine Hindlimb Ligation Model Using MCP-1 American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2003 | Pubmed ID: 12505873 Direct Evidence for Tumor Necrosis Factor-alpha Signaling in Arteriogenesis Circulation. Apr, 2002 | Pubmed ID: 11940540 Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction Guilielmus H.J.M. Ellenbroek1, Gerardus P.J. van Hout1,2, Leo Timmers1,2, Pieter A. Doevendans2,4, Gerard Pasterkamp1,3, Imo E. Hoefer1,3 1Department of Experimental Cardiology, University Medical Center Utrecht, 2Department of Cardiology, University Medical Center Utrecht, 3Department of Clinical Chemistry and Hematology, University Medical Center Utrecht, 4Interuniversity Cardiology Institutes of the Netherlands (ICIN) JoVE 54021 Medicine Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model David Stecher1, Glenn Bronkers2, Jappe O.T. Noest2, Cornelis A.F. Tulleken3, Imo E. Hoefer4, Lex A. van Herwerden1, Gerard Pasterkamp4, Marc P. Buijsrogge1 1Department of Cardiothoracic Surgery, University Medical Center Utrecht, 2Vascular Connect b.v., 3Department of Neurosurgery, University Medical Center Utrecht, 4Department of Experimental Cardiology, University Medical Center Utrecht JoVE 52127 Medicine Myocardial Infarction and Functional Outcome Assessment in Pigs Stefan Koudstaal1,2, Sanne J. Jansen of Lorkeers1, Johannes M.I.H. Gho1, Gerardus P.J van Hout1, Marlijn S. Jansen1, Paul F. Gründeman1, Gerard Pasterkamp1,2, Pieter A. Doevendans1,2, Imo E. Hoefer*1, Steven A.J. Chamuleau*1 1Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, 2Interuniversity Cardiology Institute of the Netherlands JoVE 51269 Medicine
Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction Guilielmus H.J.M. Ellenbroek1, Gerardus P.J. van Hout1,2, Leo Timmers1,2, Pieter A. Doevendans2,4, Gerard Pasterkamp1,3, Imo E. Hoefer1,3 1Department of Experimental Cardiology, University Medical Center Utrecht, 2Department of Cardiology, University Medical Center Utrecht, 3Department of Clinical Chemistry and Hematology, University Medical Center Utrecht, 4Interuniversity Cardiology Institutes of the Netherlands (ICIN) JoVE 54021 Medicine
Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model David Stecher1, Glenn Bronkers2, Jappe O.T. Noest2, Cornelis A.F. Tulleken3, Imo E. Hoefer4, Lex A. van Herwerden1, Gerard Pasterkamp4, Marc P. Buijsrogge1 1Department of Cardiothoracic Surgery, University Medical Center Utrecht, 2Vascular Connect b.v., 3Department of Neurosurgery, University Medical Center Utrecht, 4Department of Experimental Cardiology, University Medical Center Utrecht JoVE 52127 Medicine
Myocardial Infarction and Functional Outcome Assessment in Pigs Stefan Koudstaal1,2, Sanne J. Jansen of Lorkeers1, Johannes M.I.H. Gho1, Gerardus P.J van Hout1, Marlijn S. Jansen1, Paul F. Gründeman1, Gerard Pasterkamp1,2, Pieter A. Doevendans1,2, Imo E. Hoefer*1, Steven A.J. Chamuleau*1 1Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, 2Interuniversity Cardiology Institute of the Netherlands JoVE 51269 Medicine
