Articles by Irene M. Ogden in JoVE
인간의 전립선 암 전이의 동소 쥐과 모델 Janet Pavese1, Irene M. Ogden1, Raymond C. Bergan1,2,3 1Department of Medicine, Northwestern University, 2Robert H. Lurie Cancer Center, Northwestern University, 3Center for Molecular Innovation and Drug Discovery, Northwestern University 인간의 전립선 암이 동 소성 모델에 폐 종양 세포와 구별 전이의 형성을 순환, 종양 크기의 정량을 허용한다. 세포가 일차 장기 탈출해야 같이, 혈류를 입력하고, 보조 사이트에 이식,이 모델은 인간에서 효과적으로 시나리오 되풀이되었습니다.
Other articles by Irene M. Ogden on PubMed
Perfusion Preservation of the Donor Heart: Basic Science to Pre-clinical The Journal of Extra-corporeal Technology. Sep, 2009 | Pubmed ID: 19806796 As a consequence of technology improvements and refinement, perfusion of the donor heart has moved from the research laboratory to clinical studies. Multiple investigators are currently leading pre-clinical trials of devices using perfusion preservation, and one device is now in European clinical trials. One major problem with the donor heart is the high metabolism relative to other organs, and depletion of ATP leads rapidly to acidosis and necrosis of the myocardium. Two techniques in development to address the issue are normothermic and hypothermic perfusion. This review examines the current issues regarding donor heart preservation and techniques of preclinical evaluation necessary for regulatory approval.