Irving L. Weissman Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery Stanford University School of Medicine Biography Publications Institution JoVE Articles Irving L. Weissman has not added a biography. If you are Irving L. Weissman and would like to personalize this page please email our Author Liaison for assistance. Publications Ly6d Marks the Earliest Stage of B-cell Specification and Identifies the Branchpoint Between B-cell and T-cell Development Genes & Development. Sep, 2013 | Pubmed ID: 24065771 Do Pluripotent Stem Cells Exist in Adult Mice As Very Small Embryonic Stem Cells? Stem Cell Reports. 2013 | Pubmed ID: 24052953 BLT-humanized C57BL/6 Rag2-/-γc-/-CD47-/- Mice Are Resistant to GVHD and Develop B and T Cell Immunity to HIV Infection Blood. Sep, 2013 | Pubmed ID: 24021673 Isolation and Mutational Analysis of Circulating Tumor Cells from Lung Cancer Patients with Magnetic Sifters and Biochips Lab on a Chip. Aug, 2013 | Pubmed ID: 23969419 Tumorigenicity As a Clinical Hurdle for Pluripotent Stem Cell Therapies Nature Medicine. Aug, 2013 | Pubmed ID: 23921754 Use of a KIT-specific Monoclonal Antibody to Bypass Imatinib Resistance in Gastrointestinal Stromal Tumors Oncoimmunology. Jun, 2013 | Pubmed ID: 23894705 Identification of a Colonial Chordate Histocompatibility Gene Science (New York, N.Y.). Jul, 2013 | Pubmed ID: 23888037 Clonal Precursor of Bone, Cartilage, and Hematopoietic Niche Stromal Cells Proceedings of the National Academy of Sciences of the United States of America. Jul, 2013 | Pubmed ID: 23858471 The Genome Sequence of the Colonial Chordate, Botryllus Schlosseri ELife. 2013 | Pubmed ID: 23840927 Brain Tumor Stem Cell Multipotency Correlates with Nanog Expression and Extent of Passaging in Human Glioblastoma Xenografts Oncotarget. May, 2013 | Pubmed ID: 23801022 Immunogenicity of in Vitro Maintained and Matured Populations: Potential Barriers to Engraftment of Human Pluripotent Stem Cell Derivatives Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23756939 Engineered SIRPα Variants As Immunotherapeutic Adjuvants to Anticancer Antibodies Science (New York, N.Y.). Jul, 2013 | Pubmed ID: 23722425 Anti-CD47 Antibody-mediated Phagocytosis of Cancer by Macrophages Primes an Effective Antitumor T-cell Response Proceedings of the National Academy of Sciences of the United States of America. Jul, 2013 | Pubmed ID: 23690610 Synthesis of a Photocaged Tamoxifen for Light-dependent Activation of Cre-ER Recombinase-driven Gene Modification Chemical Communications (Cambridge, England). May, 2013 | Pubmed ID: 23612712 Prospective Isolation of Human Embryonic Stem Cell-derived Cardiovascular Progenitors That Integrate into Human Fetal Heart Tissue Proceedings of the National Academy of Sciences of the United States of America. Feb, 2013 | Pubmed ID: 23391730 Hematopoietic Stem Cell and Progenitor Cell Mechanisms in Myelodysplastic Syndromes Proceedings of the National Academy of Sciences of the United States of America. Feb, 2013 | Pubmed ID: 23388639 Anti-KIT Monoclonal Antibody Inhibits Imatinib-resistant Gastrointestinal Stromal Tumor Growth Proceedings of the National Academy of Sciences of the United States of America. Feb, 2013 | Pubmed ID: 23382202 Repeated, Long-term Cycling of Putative Stem Cells Between Niches in a Basal Chordate Developmental Cell. Jan, 2013 | Pubmed ID: 23260626 E. Donnall Thomas (1920-2012) Proceedings of the National Academy of Sciences of the United States of America. Dec, 2012 | Pubmed ID: 23197829 Flipping the Script on Macrophages in Leiomyosarcoma Oncoimmunology. Oct, 2012 | Pubmed ID: 23170280 In Vivo Directed Differentiation of Pluripotent Stem Cells for Skeletal Regeneration Proceedings of the National Academy of Sciences of the United States of America. Nov, 2012 | Pubmed ID: 23169671 Identification and Prospective Isolation of a Mesothelial Precursor Lineage Giving Rise to Smooth Muscle Cells and Fibroblasts for Mammalian Internal Organs, and Their Vasculature Nature Cell Biology. Dec, 2012 | Pubmed ID: 23143399 Human Neural Stem Cells Induce Functional Myelination in Mice with Severe Dysmyelination Science Translational Medicine. Oct, 2012 | Pubmed ID: 23052293 Endogenous Wnt Signalling in Human Embryonic Stem Cells Generates an Equilibrium of Distinct Lineage-specified Progenitors Nature Communications. 2012 | Pubmed ID: 22990866 The Road to Purified Hematopoietic Stem Cell Transplants is Paved with Antibodies Current Opinion in Immunology. Oct, 2012 | Pubmed ID: 22939368 Clonal Evolution of Preleukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia Science Translational Medicine. Aug, 2012 | Pubmed ID: 22932223 Remodeling of Endogenous Mammary Epithelium by Breast Cancer Stem Cells Stem Cells (Dayton, Ohio). Oct, 2012 | Pubmed ID: 22899386 Gene Expression Commons: an Open Platform for Absolute Gene Expression Profiling PloS One. 2012 | Pubmed ID: 22815738 Isolation of Primitive Endoderm, Mesoderm, Vascular Endothelial and Trophoblast Progenitors from Human Pluripotent Stem Cells Nature Biotechnology. Jun, 2012 | Pubmed ID: 22634564 Cyclin-A1 Represents a New Immunogenic Targetable Antigen Expressed in Acute Myeloid Leukemia Stem Cells with Characteristics of a Cancer-testis Antigen Blood. Jun, 2012 | Pubmed ID: 22529286 Antibody Therapy Targeting the CD47 Protein is Effective in a Model of Aggressive Metastatic Leiomyosarcoma Proceedings of the National Academy of Sciences of the United States of America. Apr, 2012 | Pubmed ID: 22451919 The CD47-signal Regulatory Protein Alpha (SIRPa) Interaction is a Therapeutic Target for Human Solid Tumors Proceedings of the National Academy of Sciences of the United States of America. Mar, 2012 | Pubmed ID: 22451913 Perturbation of the Hematopoietic System During Embryonic Liver Development Due to Disruption of Polyubiquitin Gene Ubc in Mice PloS One. 2012 | Pubmed ID: 22393459 The CD47-SIRPα Pathway in Cancer Immune Evasion and Potential Therapeutic Implications Current Opinion in Immunology. Apr, 2012 | Pubmed ID: 22310103 Three Differentiation States Risk-stratify Bladder Cancer into Distinct Subtypes Proceedings of the National Academy of Sciences of the United States of America. Feb, 2012 | Pubmed ID: 22308455 The Safety of Embryonic Stem Cell Therapy Relies on Teratoma Removal Oncotarget. Jan, 2012 | Pubmed ID: 22294556 Programmed Cell Removal: a New Obstacle in the Road to Developing Cancer Nature Reviews. Cancer. Jan, 2012 | Pubmed ID: 22158022 Long-term Outcome of Patients with Metastatic Breast Cancer Treated with High-dose Chemotherapy and Transplantation of Purified Autologous Hematopoietic Stem Cells Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Jan, 2012 | Pubmed ID: 21767515 Frequency of Cells Expressing CD44, a Head and Neck Cancer Stem Cell Marker: Correlation with Tumor Aggressiveness Head & Neck. Jan, 2012 | Pubmed ID: 21322081 Human Bone Marrow Hematopoietic Stem Cells Are Increased in Frequency and Myeloid-biased with Age Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22123971 Tracking Single Hematopoietic Stem Cells in Vivo Using High-throughput Sequencing in Conjunction with Viral Genetic Barcoding Nature Biotechnology. Oct, 2011 | Pubmed ID: 21964413 Identification of the Earliest Natural Killer Cell-committed Progenitor in Murine Bone Marrow Blood. Nov, 2011 | Pubmed ID: 21931117 Novel Hematopoietic Progenitor Populations Revealed by Direct Assessment of GATA1 Protein Expression and CMPL Signaling Events Stem Cells (Dayton, Ohio). Nov, 2011 | Pubmed ID: 21898686 Germ-layer and Lineage-restricted Stem/progenitors Regenerate the Mouse Digit Tip Nature. Aug, 2011 | Pubmed ID: 21866153 An Antibody Against SSEA-5 Glycan on Human Pluripotent Stem Cells Enables Removal of Teratoma-forming Cells Nature Biotechnology. Sep, 2011 | Pubmed ID: 21841799 Extranodal Dissemination of Non-Hodgkin Lymphoma Requires CD47 and is Inhibited by Anti-CD47 Antibody Therapy Blood. Nov, 2011 | Pubmed ID: 21828138 Enhanced Survival of Pluripotent Stem Cells Under Stressful Conditions Cell Cycle (Georgetown, Tex.). Aug, 2011 | Pubmed ID: 21791974 Reduced Ribosomal Protein Gene Dosage and P53 Activation in Low-risk Myelodysplastic Syndrome Blood. Sep, 2011 | Pubmed ID: 21788341 Prospective Separation of Normal and Leukemic Stem Cells Based on Differential Expression of TIM3, a Human Acute Myeloid Leukemia Stem Cell Marker Proceedings of the National Academy of Sciences of the United States of America. Mar, 2011 | Pubmed ID: 21383193 Hedgehog-responsive Candidate Cell of Origin for Diffuse Intrinsic Pontine Glioma Proceedings of the National Academy of Sciences of the United States of America. Mar, 2011 | Pubmed ID: 21368213 Single-cell Phospho-specific Flow Cytometric Analysis Demonstrates Biochemical and Functional Heterogeneity in Human Hematopoietic Stem and Progenitor Compartments Blood. Apr, 2011 | Pubmed ID: 21357764 Overexpression of BCL2 Enhances Survival of Human Embryonic Stem Cells During Stress and Obviates the Requirement for Serum Factors Proceedings of the National Academy of Sciences of the United States of America. Feb, 2011 | Pubmed ID: 21300885 50 Years Later: Remembering the Paper Radiation Research. Feb, 2011 | Pubmed ID: 21268706 Human Acute Myelogenous Leukemia Stem Cells Revisited: There's More Than Meets the Eye Cancer Cell. Jan, 2011 | Pubmed ID: 21251611 Purified Hematopoietic Stem Cell Transplantation: the Next Generation of Blood and Immune Replacement Hematology/oncology Clinics of North America. Feb, 2011 | Pubmed ID: 21236391 VHL Loss in Renal Cell Carcinoma Leads to Up-regulation of CUB Domain-containing Protein 1 to Stimulate PKC{delta}-driven Migration Proceedings of the National Academy of Sciences of the United States of America. Feb, 2011 | Pubmed ID: 21233420 Therapeutic Antibody Targeting of CD47 Eliminates Human Acute Lymphoblastic Leukemia Cancer Research. Feb, 2011 | Pubmed ID: 21177380 IL-1β-driven Neutrophilia Preserves Antibacterial Defense in the Absence of the Kinase IKKβ Nature Immunology. Feb, 2011 | Pubmed ID: 21170027 In Vitro Assays Misrepresent in Vivo Lineage Potentials of Murine Lymphoid Progenitors Blood. Mar, 2011 | Pubmed ID: 21163922 Calreticulin is the Dominant Pro-phagocytic Signal on Multiple Human Cancers and is Counterbalanced by CD47 Science Translational Medicine. Dec, 2010 | Pubmed ID: 21178137 MicroRNA-125b Expands Hematopoietic Stem Cells and Enriches for the Lymphoid-balanced and Lymphoid-biased Subsets Proceedings of the National Academy of Sciences of the United States of America. Dec, 2010 | Pubmed ID: 21118986 T-cell Receptor-driven Lymphomagenesis in Mice Derived from a Reprogrammed T Cell Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010 | Pubmed ID: 20956329 Cholinergic Activation of Hematopoietic Stem Cells: Role in Tobacco-related Disease? Vascular Medicine (London, England). Oct, 2010 | Pubmed ID: 20926497 Hematopoietic Stem Cell: Self-renewal Versus Differentiation Wiley Interdisciplinary Reviews. Systems Biology and Medicine. Nov-Dec, 2010 | Pubmed ID: 20890962 Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Cell. Sep, 2010 | Pubmed ID: 20813259 Comprehensive Methylome Map of Lineage Commitment from Haematopoietic Progenitors Nature. Sep, 2010 | Pubmed ID: 20720541 The Origin and Fate of Yolk Sac Hematopoiesis: Application of Chimera Analyses to Developmental Studies The International Journal of Developmental Biology. 2010 | Pubmed ID: 20711980 Position-dependent Silencing of Germline Vß Segments on TCRß Alleles Containing Preassembled VßDJßCß1 Genes Journal of Immunology (Baltimore, Md. : 1950). Sep, 2010 | Pubmed ID: 20709953 Differential DNA Damage Response in Stem and Progenitor Cells Cell Stem Cell. Aug, 2010 | Pubmed ID: 20682442 Patients Beware: Commercialized Stem Cell Treatments on the Web Cell Stem Cell. Jul, 2010 | Pubmed ID: 20621049 Human Melanoma-initiating Cells Express Neural Crest Nerve Growth Factor Receptor CD271 Nature. Jul, 2010 | Pubmed ID: 20596026 Purified Hematopoietic Stem Cell Transplantation: the Next Generation of Blood and Immune Replacement Immunology and Allergy Clinics of North America. May, 2010 | Pubmed ID: 20493393 Macrophages As Mediators of Tumor Immunosurveillance Trends in Immunology. Jun, 2010 | Pubmed ID: 20452821 Distinguishing Mast Cell and Granulocyte Differentiation at the Single-cell Level Cell Stem Cell. Apr, 2010 | Pubmed ID: 20362540 Coronary Arteries Form by Developmental Reprogramming of Venous Cells Nature. Mar, 2010 | Pubmed ID: 20336138 Functionally Distinct Hematopoietic Stem Cells Modulate Hematopoietic Lineage Potential During Aging by a Mechanism of Clonal Expansion Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010 | Pubmed ID: 20304793 MiDReG: a Method of Mining Developmentally Regulated Genes Using Boolean Implications Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010 | Pubmed ID: 20231483 MicroRNA-29a Induces Aberrant Self-renewal Capacity in Hematopoietic Progenitors, Biased Myeloid Development, and Acute Myeloid Leukemia The Journal of Experimental Medicine. Mar, 2010 | Pubmed ID: 20212066 Molecular Signatures of Quiescent, Mobilized and Leukemia-initiating Hematopoietic Stem Cells PloS One. 2010 | Pubmed ID: 20098702 Functional and Transcriptional Characterization of Human Embryonic Stem Cell-derived Endothelial Cells for Treatment of Myocardial Infarction PloS One. 2009 | Pubmed ID: 20046878 Differential Contribution of Chemotaxis and Substrate Restriction to Segregation of Immature and Mature Thymocytes Immunity. Dec, 2009 | Pubmed ID: 19962328 Niche Recycling Through Division-independent Egress of Hematopoietic Stem Cells The Journal of Experimental Medicine. Nov, 2009 | Pubmed ID: 19887396 Ly6d Marks the Earliest Stage of B-cell Specification and Identifies the Branchpoint Between B-cell and T-cell Development Genes & Development. Oct, 2009 | Pubmed ID: 19833765 Self-renewal of the Long-term Reconstituting Subset of Hematopoietic Stem Cells is Regulated by Ikaros Stem Cells (Dayton, Ohio). Dec, 2009 | Pubmed ID: 19816952 Hematopoietic Stem and Progenitor Cells and the Inflammatory Response Annals of the New York Academy of Sciences. Sep, 2009 | Pubmed ID: 19769744 Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis Cell Stem Cell. Sep, 2009 | Pubmed ID: 19733542 Identification, Molecular Characterization, Clinical Prognosis, and Therapeutic Targeting of Human Bladder Tumor-initiating Cells Proceedings of the National Academy of Sciences of the United States of America. Aug, 2009 | Pubmed ID: 19666525 CD47 is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells Cell. Jul, 2009 | Pubmed ID: 19632179 CD47 is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis Cell. Jul, 2009 | Pubmed ID: 19632178 A Neurosurgeon's Guide to Stem Cells, Cancer Stem Cells, and Brain Tumor Stem Cells Neurosurgery. Aug, 2009 | Pubmed ID: 19625901 Evaluation of the Long-term Reconstituting Subset of Hematopoietic Stem Cells with CD150 Stem Cells (Dayton, Ohio). Oct, 2009 | Pubmed ID: 19593793 Manganese-guided Cellular MRI of Human Embryonic Stem Cell and Human Bone Marrow Stromal Cell Viability Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Oct, 2009 | Pubmed ID: 19526508 Expression of AA4.1 Marks Lymphohematopoietic Progenitors in Early Mouse Development Proceedings of the National Academy of Sciences of the United States of America. Jun, 2009 | Pubmed ID: 19458045 Automated Microfluidic Chromatin Immunoprecipitation from 2,000 Cells Lab on a Chip. May, 2009 | Pubmed ID: 19417902 Sustained in Vitro Intestinal Epithelial Culture Within a Wnt-dependent Stem Cell Niche Nature Medicine. Jun, 2009 | Pubmed ID: 19398967 Glycogen Synthase Kinase 3beta Missplicing Contributes to Leukemia Stem Cell Generation Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009 | Pubmed ID: 19237556 Dysregulated Gene Expression Networks in Human Acute Myelogenous Leukemia Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009 | Pubmed ID: 19218430 Association of Reactive Oxygen Species Levels and Radioresistance in Cancer Stem Cells Nature. Apr, 2009 | Pubmed ID: 19194462 E2A Proteins Maintain the Hematopoietic Stem Cell Pool and Promote the Maturation of Myelolymphoid and Myeloerythroid Progenitors Proceedings of the National Academy of Sciences of the United States of America. Feb, 2009 | Pubmed ID: 19181846 Two-step Oligoclonal Development of Male Germ Cells Proceedings of the National Academy of Sciences of the United States of America. Jan, 2009 | Pubmed ID: 19098099 Endochondral Ossification is Required for Haematopoietic Stem-cell Niche Formation Nature. Jan, 2009 | Pubmed ID: 19078959 The Adhesion Molecule Esam1 is a Novel Hematopoietic Stem Cell Marker Stem Cells (Dayton, Ohio). Mar, 2009 | Pubmed ID: 19074415 Cancer Stem Cell-directed Therapies: Recent Data from the Laboratory and Clinic Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2009 | Pubmed ID: 19066601 CX3CR1 is Required for Monocyte Homeostasis and Atherogenesis by Promoting Cell Survival Blood. Jan, 2009 | Pubmed ID: 18971423 Reductive Isolation from Bone Marrow and Blood Implicates Common Lymphoid Progenitors As the Major Source of Thymopoiesis Blood. Jan, 2009 | Pubmed ID: 18927436 Imaging of STAT3 Signaling Pathway During Mouse Embryonic Stem Cell Differentiation Stem Cells and Development. Mar, 2009 | Pubmed ID: 18576943 Isolation of Human Fetal Liver Progenitors and Their Enhanced Proliferation by Three-dimensional Coculture with Endothelial Cells Tissue Engineering. Part A. Jun, 2008 | Pubmed ID: 19230124 In Vivo Evaluation of Human Hematopoiesis Through Xenotransplantation of Purified Hematopoietic Stem Cells from Umbilical Cord Blood Nature Protocols. 2008 | Pubmed ID: 19180077 In Vivo Serial Evaluation of Superparamagnetic Iron-oxide Labeled Stem Cells by Off-resonance Positive Contrast Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Dec, 2008 | Pubmed ID: 19030159 Wnt-mediated Self-renewal of Neural Stem/progenitor Cells Proceedings of the National Academy of Sciences of the United States of America. Nov, 2008 | Pubmed ID: 18957545 Multimodal Evaluation of in Vivo Magnetic Resonance Imaging of Myocardial Restoration by Mouse Embryonic Stem Cells The Journal of Thoracic and Cardiovascular Surgery. Oct, 2008 | Pubmed ID: 18954646 The Origins of the Identification and Isolation of Hematopoietic Stem Cells, and Their Capability to Induce Donor-specific Transplantation Tolerance and Treat Autoimmune Diseases Blood. Nov, 2008 | Pubmed ID: 18948588 Transcriptional and Functional Profiling of Human Embryonic Stem Cell-derived Cardiomyocytes PloS One. 2008 | Pubmed ID: 18941512 Identification of the Endostyle As a Stem Cell Niche in a Colonial Chordate Cell Stem Cell. Oct, 2008 | Pubmed ID: 18940736 Hematopoietic Stem Cell Quiescence is Maintained by Compound Contributions of the Retinoblastoma Gene Family Cell Stem Cell. Oct, 2008 | Pubmed ID: 18940733 Hematopoietic Stem Cells and the Aging Hematopoietic System Seminars in Hematology. Oct, 2008 | Pubmed ID: 18809091 Space-time Considerations for Hematopoietic Stem Cell Transplantation European Journal of Immunology. Aug, 2008 | Pubmed ID: 18651698 The E. Donnall Thomas Lecture: Normal and Neoplastic Stem Cells Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Aug, 2008 | Pubmed ID: 18640567 Heme Oxygenase-1 Deficiency Leads to Disrupted Response to Acute Stress in Stem Cells and Progenitors Blood. Dec, 2008 | Pubmed ID: 18509090 Bone Marrow-derived Circulating Endothelial Precursors Do Not Contribute to Vascular Endothelium and Are Not Needed for Tumor Growth Proceedings of the National Academy of Sciences of the United States of America. May, 2008 | Pubmed ID: 18443294 Flk2+ Common Lymphoid Progenitors Possess Equivalent Differentiation Potential for the B and T Lineages Blood. Jun, 2008 | Pubmed ID: 18424665 Stems Cells and the Pathways to Aging and Cancer Cell. Feb, 2008 | Pubmed ID: 18295583 Hematopoietic Stem Cell-derived Pericytic Cells in Brain Tumor Angio-architecture Stem Cells and Development. Feb, 2008 | Pubmed ID: 18240955 SIRT1 Acts As a Nutrient-sensitive Growth Suppressor and Its Loss is Associated with Increased AMPK and Telomerase Activity Molecular Biology of the Cell. Mar, 2008 | Pubmed ID: 18184747 The PIAS-like Protein Zimp10 is Essential for Embryonic Viability and Proper Vascular Development Molecular and Cellular Biology. Jan, 2008 | Pubmed ID: 17967885 Generation of a Monoclonal Antibody Library Against Human Embryonic Stem Cells Methods in Molecular Biology (Clifton, N.J.). 2007 | Pubmed ID: 18453249 Identification of a Hierarchy of Multipotent Hematopoietic Progenitors in Human Cord Blood Cell Stem Cell. Dec, 2007 | Pubmed ID: 18371405 Elucidation of the Phenotypic, Functional, and Molecular Topography of a Myeloerythroid Progenitor Cell Hierarchy Cell Stem Cell. Oct, 2007 | Pubmed ID: 18371379 Efficient Transplantation Via Antibody-based Clearance of Hematopoietic Stem Cell Niches Science (New York, N.Y.). Nov, 2007 | Pubmed ID: 18033883 Cancer Stem Cells in Solid Tumors Current Opinion in Biotechnology. Oct, 2007 | Pubmed ID: 18023337 The Effect of Bleeding on Hematopoietic Stem Cell Cycling and Self-renewal Stem Cells and Development. Oct, 2007 | Pubmed ID: 17999593 Transcriptional Profiling of Antigen-dependent Murine B Cell Differentiation and Memory Formation Journal of Immunology (Baltimore, Md. : 1950). Nov, 2007 | Pubmed ID: 17982071 Transcriptional Instability is Not a Universal Attribute of Aging Aging Cell. Dec, 2007 | Pubmed ID: 17925006 Hematopoietic Stem Cell Quiescence Attenuates DNA Damage Response and Permits DNA Damage Accumulation During Aging Cell Cycle (Georgetown, Tex.). Oct, 2007 | Pubmed ID: 17700071 Epigenetic Characterization of Hematopoietic Stem Cell Differentiation Using MiniChIP and Bisulfite Sequencing Analysis Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17640913 Pioneer Factor Interactions and Unmethylated CpG Dinucleotides Mark Silent Tissue-specific Enhancers in Embryonic Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17640912 Early TCR Expression and Aberrant T Cell Development in Mice with Endogenous Prerearranged T Cell Receptor Genes Journal of Immunology (Baltimore, Md. : 1950). Jul, 2007 | Pubmed ID: 17617584 CD96 is a Leukemic Stem Cell-specific Marker in Human Acute Myeloid Leukemia Proceedings of the National Academy of Sciences of the United States of America. Jun, 2007 | Pubmed ID: 17576927 Deficiencies in DNA Damage Repair Limit the Function of Haematopoietic Stem Cells with Age Nature. Jun, 2007 | Pubmed ID: 17554309 Stem Cells: Blood Lines from Embryo to Adult Nature. Apr, 2007 | Pubmed ID: 17460657 Reversal of Autoimmune Disease in Lupus-prone New Zealand Black/New Zealand White Mice by Nonmyeloablative Transplantation of Purified Allogeneic Hematopoietic Stem Cells Blood. Aug, 2007 | Pubmed ID: 17435112 Bmi-1-green Fluorescent Protein-knock-in Mice Reveal the Dynamic Regulation of Bmi-1 Expression in Normal and Leukemic Hematopoietic Cells Stem Cells (Dayton, Ohio). Jul, 2007 | Pubmed ID: 17395774 Molecular Imaging of Embryonic Stem Cell Misbehavior and Suicide Gene Ablation Cloning and Stem Cells. 2007 | Pubmed ID: 17386018 Striving for Normality: Whole Body Regeneration Through a Series of Abnormal Generations FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2007 | Pubmed ID: 17289924 Hematopoietic Stem Cell Aging: Mechanism and Consequence Experimental Gerontology. May, 2007 | Pubmed ID: 17275237 Ethics. The ISSCR Guidelines for Human Embryonic Stem Cell Research Science (New York, N.Y.). Feb, 2007 | Pubmed ID: 17272706 B-cell Development Fails in the Absence of the Pbx1 Proto-oncogene Blood. May, 2007 | Pubmed ID: 17244677 Hematopoietic Reconstitution by Multipotent Adult Progenitor Cells: Precursors to Long-term Hematopoietic Stem Cells The Journal of Experimental Medicine. Jan, 2007 | Pubmed ID: 17227908 Hematopoietic Stem Cells: Expression Profiling and Beyond Stem Cell Reviews. 2006 | Pubmed ID: 17142883 Transcription Factor Profiling in Individual Hematopoietic Progenitors by Digital RT-PCR Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006 | Pubmed ID: 17098862 The Cancer Stem Cell Hypothesis: a Work in Progress Laboratory Investigation; a Journal of Technical Methods and Pathology. Dec, 2006 | Pubmed ID: 17075578 Clonal Analysis of Mouse Development Reveals a Polyclonal Origin for Yolk Sac Blood Islands Developmental Cell. Oct, 2006 | Pubmed ID: 17011491 Cancer Stem Cells--perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells Cancer Research. Oct, 2006 | Pubmed ID: 16990346 Hematopoietic Stem Cells: the Paradigmatic Tissue-specific Stem Cell The American Journal of Pathology. Aug, 2006 | Pubmed ID: 16877336 New Evidence Supporting Megakaryocyte-erythrocyte Potential of Flk2/flt3+ Multipotent Hematopoietic Progenitors Cell. Jul, 2006 | Pubmed ID: 16873070 Fester, A Candidate Allorecognition Receptor from a Primitive Chordate Immunity. Jul, 2006 | Pubmed ID: 16860765 A Cell-surface Molecule Involved in Organ-specific Homing of Lymphocytes. 1983 Journal of Immunology (Baltimore, Md. : 1950). Jul, 2006 | Pubmed ID: 16785489 Rapid Lymphocyte Reconstitution of Unconditioned Immunodeficient Mice with Non-self-renewing Multipotent Hematopoietic Progenitors Cell Cycle (Georgetown, Tex.). Jun, 2006 | Pubmed ID: 16760650 Pten, Tumorigenesis, and Stem Cell Self-renewal Cell. Apr, 2006 | Pubmed ID: 16630811 The JAK2 V617F Mutation Occurs in Hematopoietic Stem Cells in Polycythemia Vera and Predisposes Toward Erythroid Differentiation Proceedings of the National Academy of Sciences of the United States of America. Apr, 2006 | Pubmed ID: 16603627 Memory T and Memory B Cells Share a Transcriptional Program of Self-renewal with Long-term Hematopoietic Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006 | Pubmed ID: 16492737 In Vivo Visualization of Embryonic Stem Cell Survival, Proliferation, and Migration After Cardiac Delivery Circulation. Feb, 2006 | Pubmed ID: 16476845 Medicine: Politic Stem Cells Nature. Jan, 2006 | Pubmed ID: 16407938 Antagonistic Effect of CCAAT Enhancer-binding Protein-alpha and Pax5 in Myeloid or Lymphoid Lineage Choice in Common Lymphoid Progenitors Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006 | Pubmed ID: 16407117 Purified Hematopoietic Stem Cell Engraftment of Rare Niches Corrects Severe Lymphoid Deficiencies Without Host Conditioning The Journal of Experimental Medicine. Jan, 2006 | Pubmed ID: 16380511 Differential Expression of Alpha2 Integrin Separates Long-term and Short-term Reconstituting Lin-/loThy1.1(lo)c-kit+ Sca-1+ Hematopoietic Stem Cells Stem Cells (Dayton, Ohio). Apr, 2006 | Pubmed ID: 16373693 Flk2+ Myeloid Progenitors Are the Main Source of Langerhans Cells Blood. Feb, 2006 | Pubmed ID: 16263793 Differential Amplification of Murine Bipotent Megakaryocytic/erythroid Progenitor and Precursor Cells During Recovery from Acute and Chronic Erythroid Stress Stem Cells (Dayton, Ohio). Feb, 2006 | Pubmed ID: 16144876 Stem Cells Are Units of Natural Selection in a Colonial Ascidian Cell. Dec, 2005 | Pubmed ID: 16377573 Global Analysis of Proliferation and Cell Cycle Gene Expression in the Regulation of Hematopoietic Stem and Progenitor Cell Fates The Journal of Experimental Medicine. Dec, 2005 | Pubmed ID: 16330818 Isolation and Characterization of a Protochordate Histocompatibility Locus Nature. Nov, 2005 | Pubmed ID: 16306984 Identification of a Novel Gene Involved in Asexual Organogenesis in the Budding Ascidian Botryllus Schlosseri Developmental Dynamics : an Official Publication of the American Association of Anatomists. Dec, 2005 | Pubmed ID: 16193502 Stepwise Development of Committed Progenitors in the Bone Marrow That Generate Functional T Cells in the Absence of the Thymus Journal of Immunology (Baltimore, Md. : 1950). Oct, 2005 | Pubmed ID: 16177077 Differential Expression of Novel Potential Regulators in Hematopoietic Stem Cells PLoS Genetics. Sep, 2005 | Pubmed ID: 16151515 Simple and Efficient Isolation of Hematopoietic Stem Cells from H2K-zFP Transgenic Mice Stem Cells (Dayton, Ohio). Nov-Dec, 2005 | Pubmed ID: 16091556 Normal and Neoplastic Stem Cells Novartis Foundation Symposium. 2005 | Pubmed ID: 16050249 Surface Phenotype of Peyer's Patch Germinal Center Cells: Implications for the Role of Germinal Centers in B Cell Differentiation. 1982 Journal of Immunology (Baltimore, Md. : 1950). Aug, 2005 | Pubmed ID: 16034071 Identification of Mast Cell Progenitors in Adult Mice Proceedings of the National Academy of Sciences of the United States of America. Aug, 2005 | Pubmed ID: 16006518 Cell Intrinsic Alterations Underlie Hematopoietic Stem Cell Aging Proceedings of the National Academy of Sciences of the United States of America. Jun, 2005 | Pubmed ID: 15967997 Hematopoietic Cells Maintain Hematopoietic Fates Upon Entering the Brain The Journal of Experimental Medicine. May, 2005 | Pubmed ID: 15897275 Stimulation of Paracrine Pathways with Growth Factors Enhances Embryonic Stem Cell Engraftment and Host-specific Differentiation in the Heart After Ischemic Myocardial Injury Circulation. May, 2005 | Pubmed ID: 15883216 Enforced Bcl-2 Expression Overrides Serum and Feeder Cell Requirements for Mouse Embryonic Stem Cell Self-renewal Proceedings of the National Academy of Sciences of the United States of America. Mar, 2005 | Pubmed ID: 15728354 Rejuvenation of Aged Progenitor Cells by Exposure to a Young Systemic Environment Nature. Feb, 2005 | Pubmed ID: 15716955 Developmental Origin of Interferon-alpha-producing Dendritic Cells from Hematopoietic Precursors Experimental Hematology. Feb, 2005 | Pubmed ID: 15676211 Hematopoietic Stem and Progenitor Cells: Clinical and Preclinical Regeneration of the Hematolymphoid System Annual Review of Medicine. 2005 | Pubmed ID: 15660525 Frizzled 9 Knock-out Mice Have Abnormal B-cell Development Blood. Mar, 2005 | Pubmed ID: 15572594 Selection of Aberrant Class II Restricted CD8+ T Cells in NOD Mice Expressing a Glutamic Acid Decarboxylase (GAD)65-specific T Cell Receptor Transgene Autoimmunity. Dec, 2004 | Pubmed ID: 15763918 Chronic Versus Acute Myelogenous Leukemia: a Question of Self-renewal Cancer Cell. Dec, 2004 | Pubmed ID: 15607956 Determinants of Skeletal Muscle Contributions from Circulating Cells, Bone Marrow Cells, and Hematopoietic Stem Cells Stem Cells (Dayton, Ohio). 2004 | Pubmed ID: 15579647 Insulin-like Growth Factor Promotes Engraftment, Differentiation, and Functional Improvement After Transfer of Embryonic Stem Cells for Myocardial Restoration Stem Cells (Dayton, Ohio). 2004 | Pubmed ID: 15579642 Isolation of Adult Mouse Myogenic Progenitors: Functional Heterogeneity of Cells Within and Engrafting Skeletal Muscle Cell. Nov, 2004 | Pubmed ID: 15537543 JunB Deficiency Leads to a Myeloproliferative Disorder Arising from Hematopoietic Stem Cells Cell. Oct, 2004 | Pubmed ID: 15507213 Telomerase Maintained in Self-renewing Tissues During Serial Regeneration of the Urochordate Botryllus Schlosseri Developmental Biology. Sep, 2004 | Pubmed ID: 15328006 Granulocyte-macrophage Progenitors As Candidate Leukemic Stem Cells in Blast-crisis CML The New England Journal of Medicine. Aug, 2004 | Pubmed ID: 15306667 Depletion of Host Langerhans Cells Before Transplantation of Donor Alloreactive T Cells Prevents Skin Graft-versus-host Disease Nature Medicine. May, 2004 | Pubmed ID: 15098028 Leukemic Transformation of Hematopoietic Progenitors by MLL-GAS7 in the Absence of Hoxa7 or Hoxa9 Blood. Apr, 2004 | Pubmed ID: 15070702 Haematopoietic Stem Cells Adopt Mature Haematopoietic Fates in Ischaemic Myocardium Nature. Apr, 2004 | Pubmed ID: 15034594 Circulation and Chemotaxis of Fetal Hematopoietic Stem Cells PLoS Biology. Mar, 2004 | Pubmed ID: 15024423 Plasticity of Adult Stem Cells Cell. Mar, 2004 | Pubmed ID: 15006347 Evolution of a Protochordate Allorecognition Locus Science (New York, N.Y.). Feb, 2004 | Pubmed ID: 14963321 Osteoclast Utledning fra Mouse Bone Marrow Ruth Tevlin*1, Adrian McArdle*1,2, Charles K.F. Chan2, John Pluvinage2, Graham G. Walmsley1,2, Taylor Wearda1,2, Owen Marecic1,2, Michael S. Hu1, Kevin J. Paik1, Kshemendra Senarath-Yapa1, David A. Atashroo1, Elizabeth R. Zielins1, Derrick C. Wan1, Irving L. Weissman1,2, Michael T. Longaker1,2 1Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, 2Institute for Stem Cell Biology and Regenerative Medicine, Stanford University JoVE 52056 Biology Parabiosis i Mus: En detaljert protokoll Paniz Kamran1,2, Konstantina-Ioanna Sereti1,2, Peng Zhao1,2, Shah R. Ali3, Irving L. Weissman3, Reza Ardehali1,2 1Department of Medicine-Division of Cardiology, University of California, Los Angeles, 2Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, 3Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine JoVE 50556 Medicine
Osteoclast Utledning fra Mouse Bone Marrow Ruth Tevlin*1, Adrian McArdle*1,2, Charles K.F. Chan2, John Pluvinage2, Graham G. Walmsley1,2, Taylor Wearda1,2, Owen Marecic1,2, Michael S. Hu1, Kevin J. Paik1, Kshemendra Senarath-Yapa1, David A. Atashroo1, Elizabeth R. Zielins1, Derrick C. Wan1, Irving L. Weissman1,2, Michael T. Longaker1,2 1Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, 2Institute for Stem Cell Biology and Regenerative Medicine, Stanford University JoVE 52056 Biology
Parabiosis i Mus: En detaljert protokoll Paniz Kamran1,2, Konstantina-Ioanna Sereti1,2, Peng Zhao1,2, Shah R. Ali3, Irving L. Weissman3, Reza Ardehali1,2 1Department of Medicine-Division of Cardiology, University of California, Los Angeles, 2Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, 3Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine JoVE 50556 Medicine
