J. Michael Dixon Breakthrough Breast Cancer Research Unit, Institute of Genetics and Molecular Medicine University of Edinburgh Biography Publications Institution JoVE Articles J. Michael Dixon has not added a biography. If you are J. Michael Dixon and would like to personalize this page please email our Author Liaison for assistance. Publications Congenital Abnormalities of the Breast Women's Health (London, England). Jan, 2012 | Pubmed ID: 22171777 Determining Tamoxifen Sensitivity Using Primary Breast Cancer Tissue in Collagen-based Three-dimensional Culture Biomaterials. Jan, 2012 | Pubmed ID: 22048005 Impact of Screening and Risk Factors for Local Recurrence and Survival After Conservative Surgery and Radiotherapy for Early Breast Cancer: Results from a Large Series with Long-Term Follow-Up International Journal of Radiation Oncology, Biology, Physics. Dec, 2011 | Pubmed ID: 22197227 Relative Impact of Key Sources of Systematic Noise in Affymetrix and Illumina Gene-expression Microarray Experiments BMC Genomics. 2011 | Pubmed ID: 22133085 Tissue Type is a Major Modifier of the 5-hydroxymethylcytosine Content of Human Genes Genome Research. Dec, 2011 | Pubmed ID: 22106369 Low Residual Proliferation After Short-term Letrozole Therapy is an Early Predictive Marker of Response in High Proliferative ER-positive Breast Cancer Endocrine-related Cancer. Oct, 2011 | Pubmed ID: 21984694 Constructing Tissue Microarrays from Core Needle Biopsies of Breast Cancers Histopathology. Oct, 2011 | Pubmed ID: 21906129 Invasive Lobular Carcinoma: Response to Neoadjuvant Letrozole Therapy Breast Cancer Research and Treatment. Dec, 2011 | Pubmed ID: 21870129 Transcriptionally Repressed Genes Become Aberrantly Methylated and Distinguish Tumors of Different Lineages in Breast Cancer Proceedings of the National Academy of Sciences of the United States of America. Mar, 2011 | Pubmed ID: 21368160 Implant-Based Augmentation Mammaplasty Following Breast Conservation Surgery Annals of Plastic Surgery. Feb, 2011 | Pubmed ID: 21346535 Response to MTOR Inhibition: Activity of EIF4E Predicts Sensitivity in Cell Lines and Acquired Changes in EIF4E Regulation in Breast Cancer Molecular Cancer. 2011 | Pubmed ID: 21320304 Treatment of Breast Infection BMJ (Clinical Research Ed.). 2011 | Pubmed ID: 21317199 DCIS of the Breast: Are We Over-diagnosing It? Are We Over-treating It? Maturitas. Apr, 2011 | Pubmed ID: 21273014 Anastrozole and Letrozole: an Investigation and Comparison of Quality of Life and Tolerability Breast Cancer Research and Treatment. Feb, 2011 | Pubmed ID: 20821047 European Journal of Cancer (Oxford, England : 1990). Dec, 2010 | Pubmed ID: 20817513 Dynamic Changes in Gene Expression in Vivo Predict Prognosis of Tamoxifen-treated Patients with Breast Cancer Breast Cancer Research : BCR. 2010 | Pubmed ID: 20569502 A Further Survey of Surgical Management of the Axilla in UK Breast Cancer Patients Annals of the Royal College of Surgeons of England. Sep, 2010 | Pubmed ID: 20522293 Gene Expression Profiling of Response to MTOR Inhibitor Everolimus in Pre-operatively Treated Post-menopausal Women with Oestrogen Receptor-positive Breast Cancer Breast Cancer Research and Treatment. Jul, 2010 | Pubmed ID: 20480226 Combining and Sequencing Adjuvant Chemotherapy and Tamoxifen in Postmenopausal Women with Node-positive Breast Cancer Women's Health (London, England). May, 2010 | Pubmed ID: 20426600 Correcting for Intra-experiment Variation in Illumina BeadChip Data is Necessary to Generate Robust Gene-expression Profiles BMC Genomics. 2010 | Pubmed ID: 20181233 Cyclooxygenase-2 Inhibition Does Not Improve the Reduction in Ductal Carcinoma in Situ Proliferation with Aromatase Inhibitor Therapy: Results of the ERISAC Randomized Placebo-controlled Trial Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2010 | Pubmed ID: 20179229 Detection of PIK3CA Mutations in Circulating Free DNA in Patients with Breast Cancer Breast Cancer Research and Treatment. Apr, 2010 | Pubmed ID: 20107891 So You Want to Be ... a Breast Surgeon British Journal of Hospital Medicine (London, England : 2005). Jan, 2010 | Pubmed ID: 20081651 Functional Genetic Polymorphisms in the Aromatase Gene CYP19 Vary the Response of Breast Cancer Patients to Neoadjuvant Therapy with Aromatase Inhibitors Cancer Research. Jan, 2010 | Pubmed ID: 20048079 A Study of the Effects of the Aromatase Inhibitors Anastrozole and Letrozole on Bone Metabolism in Postmenopausal Women with Estrogen Receptor-positive Breast Cancer Breast Cancer Research and Treatment. Feb, 2010 | Pubmed ID: 19941160 Breast Screening Has Increased the Number of Mastectomies Breast Cancer Research : BCR. 2009 | Pubmed ID: 20030870 Magnetic Resonance Imaging Screening of the Contralateral Breast in Women with Newly Diagnosed Breast Cancer: Systematic Review and Meta-analysis of Incremental Cancer Detection and Impact on Surgical Management Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Nov, 2009 | Pubmed ID: 19805685 Residual Breast Cancers After Conventional Therapy Display Mesenchymal As Well As Tumor-initiating Features Proceedings of the National Academy of Sciences of the United States of America. Aug, 2009 | Pubmed ID: 19666588 Phase II Randomized Study of Neoadjuvant Everolimus Plus Letrozole Compared with Placebo Plus Letrozole in Patients with Estrogen Receptor-positive Breast Cancer Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2009 | Pubmed ID: 19380449 Gene Expression Profiles Differentiating Between Breast Cancers Clinically Responsive or Resistant to Letrozole Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2009 | Pubmed ID: 19224856 Adjuvant Endocrine Therapy for Perimenopausal Women with Early Breast Cancer Breast (Edinburgh, Scotland). Feb, 2009 | Pubmed ID: 19036588 Increase in Response Rate by Prolonged Treatment with Neoadjuvant Letrozole Breast Cancer Research and Treatment. Jan, 2009 | Pubmed ID: 18264759 Extended Follow-up of Breast Cancer Patients in Clinic Wastes Time for Both Patients and Doctors: the Case For Breast Cancer Research : BCR. 2008 | Pubmed ID: 19128445 Introduction to Sessions on 'What Can Surgeons Do for Us (and We for Them): Radiology, Pathology, Molecular Biology and Local Therapy' Breast Cancer Research : BCR. 2008 | Pubmed ID: 19128433 Breast Cancer Risk Reduction and Membrane-bound Catechol O-methyltransferase Genetic Polymorphisms Cancer Research. Jul, 2008 | Pubmed ID: 18632656 Predictors of Mastectomy in a Certified Breast Center - the Surgeon is an Independent Risk Factor The Breast Journal. Jul-Aug, 2008 | Pubmed ID: 18537918 Reducing Early Recurrence with Adjuvant Aromatase Inhibitors: What is the Evidence? Breast (Edinburgh, Scotland). Aug, 2008 | Pubmed ID: 18490163 Accuracy and Surgical Impact of Magnetic Resonance Imaging in Breast Cancer Staging: Systematic Review and Meta-analysis in Detection of Multifocal and Multicentric Cancer Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jul, 2008 | Pubmed ID: 18474876 Letrozole Suppresses Plasma Estradiol and Estrone Sulphate More Completely Than Anastrozole in Postmenopausal Women with Breast Cancer Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Apr, 2008 | Pubmed ID: 18375896 Prospects of Neoadjuvant Aromatase Inhibitor Therapy in Breast Cancer Expert Review of Anticancer Therapy. Mar, 2008 | Pubmed ID: 18366292 Predicting Response and Resistance to Endocrine Therapy: Profiling Patients on Aromatase Inhibitors Cancer. Feb, 2008 | Pubmed ID: 18072233 Breast Abscess British Journal of Hospital Medicine (London, England : 2005). Jun, 2007 | Pubmed ID: 17639835 Aromatase Inhibitors--gene Discovery The Journal of Steroid Biochemistry and Molecular Biology. Aug-Sep, 2007 | Pubmed ID: 17616392 DCIS and Aromatase Inhibitors The Journal of Steroid Biochemistry and Molecular Biology. Aug-Sep, 2007 | Pubmed ID: 17604618 Molecular Response to Aromatase Inhibitor Treatment in Primary Breast Cancer Breast Cancer Research : BCR. 2007 | Pubmed ID: 17555561 Neoadjuvant Use of Endocrine Therapy in Breast Cancer The Breast Journal. May-Jun, 2007 | Pubmed ID: 17461898 Prognostic Value of Ki67 Expression After Short-term Presurgical Endocrine Therapy for Primary Breast Cancer Journal of the National Cancer Institute. Jan, 2007 | Pubmed ID: 17228000 Aromatase Inhibitors in Early Breast Cancer Therapy: a Variety of Treatment Strategies Expert Opinion on Pharmacotherapy. Dec, 2006 | Pubmed ID: 17150002 Neoadjuvant Use of Hormonal Therapy in Elderly Patients with Early or Locally Advanced Hormone Receptor-positive Breast Cancer The Oncologist. Nov-Dec, 2006 | Pubmed ID: 17110627 Estrogen Receptor Alpha Positive Breast Tumors and Breast Cancer Cell Lines Share Similarities in Their Transcriptome Data Structures International Journal of Oncology. Dec, 2006 | Pubmed ID: 17089000 Consensus Conference on Breast Conservation Journal of the American College of Surgeons. Aug, 2006 | Pubmed ID: 16864033 Proceedings of the Consensus Conference on Breast Conservation, April 28 to May 1, 2005, Milan, Italy Cancer. Jul, 2006 | Pubmed ID: 16770785 Extended Adjuvant Therapy with Letrozole: Reducing the Risk of Recurrence Expert Review of Anticancer Therapy. Jun, 2006 | Pubmed ID: 16761928 Estrogen-independent Proliferation is Present in Estrogen-receptor HER2-positive Primary Breast Cancer After Neoadjuvant Letrozole Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jul, 2006 | Pubmed ID: 16754938 Randomized Multicenter Trial of Sentinel Node Biopsy Versus Standard Axillary Treatment in Operable Breast Cancer: the ALMANAC Trial Journal of the National Cancer Institute. May, 2006 | Pubmed ID: 16670385 The Prevention, Detection, and Management of Breast Cancer The Medical Journal of Australia. Mar, 2006 | Pubmed ID: 16515434 Screening for Breast Cancer BMJ (Clinical Research Ed.). Mar, 2006 | Pubmed ID: 16513688 Neoadjuvant Endocrine Therapy Models Methods in Molecular Medicine. 2006 | Pubmed ID: 16491621 Proliferation and Apoptosis As Markers of Benefit in Neoadjuvant Endocrine Therapy of Breast Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2006 | Pubmed ID: 16467120 Post-operative Arm Morbidity and Quality of Life. Results of the ALMANAC Randomised Trial Comparing Sentinel Node Biopsy with Standard Axillary Treatment in the Management of Patients with Early Breast Cancer Breast Cancer Research and Treatment. Feb, 2006 | Pubmed ID: 16163445 Translation Elongation Factor EEF1A2 is a Potential Oncoprotein That is Overexpressed in Two-thirds of Breast Tumours BMC Cancer. 2005 | Pubmed ID: 16156888 Breast Cancer (non-metastatic) Clinical Evidence. Jun, 2005 | Pubmed ID: 16135326 Surgical Issues Surrounding Use of Aromatase Inhibitors The Journal of Steroid Biochemistry and Molecular Biology. May, 2005 | Pubmed ID: 16023854 Neoadjuvant Treatment of Postmenopausal Breast Cancer with Anastrozole, Tamoxifen, or Both in Combination: the Immediate Preoperative Anastrozole, Tamoxifen, or Combined with Tamoxifen (IMPACT) Multicenter Double-blind Randomized Trial Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Aug, 2005 | Pubmed ID: 15998903 Biomarker Changes During Neoadjuvant Anastrozole, Tamoxifen, or the Combination: Influence of Hormonal Status and HER-2 in Breast Cancer--a Study from the IMPACT Trialists Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Apr, 2005 | Pubmed ID: 15767642 Short-term Changes in Ki-67 During Neoadjuvant Treatment of Primary Breast Cancer with Anastrozole or Tamoxifen Alone or Combined Correlate with Recurrence-free Survival Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2005 | Pubmed ID: 15701892 Breast Cancer (non-metastatic) Clinical Evidence. Jun, 2004 | Pubmed ID: 15652112 The Scientific Value of Preoperative Studies and How They Can Be Used Breast Cancer Research and Treatment. 2004 | Pubmed ID: 15597217 Role of Endocrine Therapy in the Neoadjuvant Surgical Setting Annals of Surgical Oncology. Jan, 2004 | Pubmed ID: 15015705 Exemestane and Aromatase Inhibitors in the Management of Advanced Breast Cancer Expert Opinion on Pharmacotherapy. Feb, 2004 | Pubmed ID: 14996627 Breast Cancer (non-metastatic) Clinical Evidence. Jun, 2003 | Pubmed ID: 12967459 Breast Cancer: Non-metastatic Clinical Evidence. Dec, 2002 | Pubmed ID: 12603971 Message About Hormone Replacement Therapy is Unclear BMJ (Clinical Research Ed.). Nov, 2002 | Pubmed ID: 12411373 Breast Cancer: Non-metastatic Clinical Evidence. Jun, 2002 | Pubmed ID: 12230775 Postcode Prescribing is Alive and Well in Scotland BMJ (Clinical Research Ed.). Jul, 2002 | Pubmed ID: 12114247 Exemestane: a Potent Irreversible Aromatase Inactivator and a Promising Advance in Breast Cancer Treatment Expert Review of Anticancer Therapy. Jun, 2002 | Pubmed ID: 12113050 Endocrine and Clinical Endpoints of Exemestane As Neoadjuvant Therapy Cancer Control : Journal of the Moffitt Cancer Center. Mar-Apr, 2002 | Pubmed ID: 11965226 One Stop Clinics Should Not Be Abandoned BMJ (Clinical Research Ed.). Mar, 2002 | Pubmed ID: 11876172 The Value of Adjuvant Treatment in Young Women with Breast Cancer Drugs. 2002 | Pubmed ID: 11790154 Long-term Culture of Human Breast Cancer Specimens and Their Analysis Using Optical Projection Tomography Alexander D. Leeper1, Joanne Farrell2, J. Michael Dixon1, Sarah E. Wedden2, David J. Harrison1, Elad Katz1 1Breakthrough Breast Cancer Research Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, 2MRC Technology JoVE 3085 Biology
Long-term Culture of Human Breast Cancer Specimens and Their Analysis Using Optical Projection Tomography Alexander D. Leeper1, Joanne Farrell2, J. Michael Dixon1, Sarah E. Wedden2, David J. Harrison1, Elad Katz1 1Breakthrough Breast Cancer Research Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, 2MRC Technology JoVE 3085 Biology