Jacob H. Hanna

Publications

• Mechanism of Noncoding RNA-associated N-methyladenosine Recognition by an RNA Processing Complex During IgH DNA Recombination
  Molecular Cell. Oct, 2021  |   Pubmed ID: 34450044
• The Germinal Center Reaction Depends on RNA Methylation and Divergent Functions of Specific Methyl Readers
  The Journal of Experimental Medicine. Oct, 2021  |   Pubmed ID: 34402854
• Modeling Genetic Epileptic Encephalopathies Using Brain Organoids
  EMBO Molecular Medicine. Aug, 2021  |   Pubmed ID: 34268881
• Principles of Signaling Pathway Modulation for Enhancing Human Naive Pluripotency Induction
  Cell Stem Cell. 09, 2021  |   Pubmed ID: 33915080
• Ex Utero Mouse Embryogenesis from Pre-gastrulation to Late Organogenesis
  Nature. 05, 2021  |   Pubmed ID: 33731940
• Production and Analysis of Human Primordial Germ Cell-Like Cells
  Methods in Molecular Biology (Clifton, N.J.). 2021  |   Pubmed ID: 32852762
• Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis
  Molecular Cell. 12, 2020  |   Pubmed ID: 33217318
• Context-dependent Functional Compensation Between Ythdf MA Reader Proteins
  Genes & Development. 10, 2020  |   Pubmed ID: 32943573
• β-Catenin Safeguards the Ground State of Mousepluripotency by Strengthening the Robustness of the Transcriptional Apparatus
  Science Advances. Jul, 2020  |   Pubmed ID: 32832621
• Generation of Human Endothelium in Pig Embryos Deficient in ETV2
  Nature Biotechnology. 03, 2020  |   Pubmed ID: 32094659
• Deciphering the "mA Code" Via Antibody-Independent Quantitative Profiling
  Cell. 07, 2019  |   Pubmed ID: 31257032
• Stage-specific Requirement for Mettl3-dependent MA MRNA Methylation During Haematopoietic Stem Cell Differentiation
  Nature Cell Biology. 06, 2019  |   Pubmed ID: 31061465
• Universally Non-immunogenic IPSCs
  Nature Biomedical Engineering. 05, 2019  |   Pubmed ID: 31036889
• Stem Cell-Derived Human Gametes: The Public Engagement Imperative
  Trends in Molecular Medicine. 03, 2019  |   Pubmed ID: 30738627
• Publisher Correction: M6A Modification Controls the Innate Immune Response to Infection by Targeting Type I Interferons
  Nature Immunology. 02, 2019  |   Pubmed ID: 30635652
• The N-Methyladenosine MRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy
  Circulation. 01, 2019  |   Pubmed ID: 30586742
• MA Modification Controls the Innate Immune Response to Infection by Targeting Type I Interferons
  Nature Immunology. 02, 2019  |   Pubmed ID: 30559377
• Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules
  Cell Stem Cell. Dec, 2018  |   Pubmed ID: 30554962
• MTCH2-mediated Mitochondrial Fusion Drives Exit from Naïve Pluripotency in Embryonic Stem Cells
  Nature Communications. 12, 2018  |   Pubmed ID: 30510213
• Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency
  Cell Stem Cell. Sep, 2018  |   Pubmed ID: 30122475
• The Role of MA/m-RNA Methylation in Stress Response Regulation
  Neuron. Jul, 2018  |   Pubmed ID: 30048615
• Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies
  Immunity. May, 2018  |   Pubmed ID: 29768178
• Human Brain Organoids on a Chip Reveal the Physics of Folding
  Nature Physics. May, 2018  |   Pubmed ID: 29760764
• MA Deposition: a Boost from TGFβ
  Cell Research. May, 2018  |   Pubmed ID: 29679051
• RAS Regulates the Transition from Naive to Primed Pluripotent Stem Cells
  Stem Cell Reports. 03, 2018  |   Pubmed ID: 29456180
• NKp46 Receptor-Mediated Interferon-γ Production by Natural Killer Cells Increases Fibronectin 1 to Alter Tumor Architecture and Control Metastasis
  Immunity. 01, 2018  |   Pubmed ID: 29329948
• Relevance of IPSC-derived Human PGC-like Cells at the Surface of Embryoid Bodies to Prechemotaxis Migrating PGCs
  Proceedings of the National Academy of Sciences of the United States of America. 11, 2017  |   Pubmed ID: 29087313
• OCT4 Impedes Cell Fate Redirection by the Melanocyte Lineage Master Regulator MITF in Mouse ESCs
  Nature Communications. Oct, 2017  |   Pubmed ID: 29044103
• Increased NK Cell Immunity in a Transgenic Mouse Model of NKp46 Overexpression
  Scientific Reports. 10, 2017  |   Pubmed ID: 29026144
• A Multiplexed Screening Method for Pluripotency
  Stem Cell Research. 08, 2017  |   Pubmed ID: 28756340
• MA MRNA Modifications Are Deposited in Nascent Pre-mRNA and Are Not Required for Splicing but Do Specify Cytoplasmic Turnover
  Genes & Development. 05, 2017  |   Pubmed ID: 28637692
• Transcriptional Programs That Control Expression of the Autoimmune Regulator Gene Aire
  Nature Immunology. 02, 2017  |   Pubmed ID: 27941786
• Co-ChIP Enables Genome-wide Mapping of Histone Mark Co-occurrence at Single-molecule Resolution
  Nature Biotechnology. 09, 2016  |   Pubmed ID: 27454738
• Dynamic Stem Cell States: Naive to Primed Pluripotency in Rodents and Humans
  Nature Reviews. Molecular Cell Biology. Mar, 2016  |   Pubmed ID: 26860365
• Evolutionary Analysis Across Mammals Reveals Distinct Classes of Long Non-coding RNAs
  Genome Biology. Feb, 2016  |   Pubmed ID: 26838501
• An Essential Role for UTX in Resolution and Activation of Bivalent Promoters
  Nucleic Acids Research. 05, 2016  |   Pubmed ID: 26762983
• Failure to Replicate the STAP Cell Phenomenon
  Nature. Sep, 2015  |   Pubmed ID: 26399835
• Establishing the Human Naïve Pluripotent State
  Current Opinion in Genetics & Development. Oct, 2015  |   Pubmed ID: 26291026
• Transient Acquisition of Pluripotency During Somatic Cell Transdifferentiation with IPSC Reprogramming Factors
  Nature Biotechnology. Jul, 2015  |   Pubmed ID: 26098448
• CD24 Tracks Divergent Pluripotent States in Mouse and Human Cells
  Nature Communications. Jun, 2015  |   Pubmed ID: 26076835
• Stem Cells. M6A MRNA Methylation Facilitates Resolution of Naïve Pluripotency Toward Differentiation
  Science (New York, N.Y.). Feb, 2015  |   Pubmed ID: 25569111
• SOX17 is a Critical Specifier of Human Primordial Germ Cell Fate
  Cell. Jan, 2015  |   Pubmed ID: 25543152
• Hijacked by an Oocyte: Hierarchical Molecular Changes in Somatic Cell Nuclear Transfer
  Molecular Cell. Aug, 2014  |   Pubmed ID: 25148360
• Stem Cells: The Quest for the Perfect Reprogrammed Cell
  Nature. Jul, 2014  |   Pubmed ID: 25008516
• Lucky IPSCs
  Genome Biology. Mar, 2014  |   Pubmed ID: 25002192
• Passage Number is a Major Contributor to Genomic Structural Variations in Mouse IPSCs
  Stem Cells (Dayton, Ohio). Oct, 2014  |   Pubmed ID: 24965231
• Derivation of Novel Human Ground State Naive Pluripotent Stem Cells
  Nature. Dec, 2013  |   Pubmed ID: 24172903
• Deterministic Direct Reprogramming of Somatic Cells to Pluripotency
  Nature. Oct, 2013  |   Pubmed ID: 24048479
• The Expression of the Beta Cell-derived Autoimmune Ligand for the Killer Receptor Nkp46 is Attenuated in Type 2 Diabetes
  PloS One. 2013  |   Pubmed ID: 24009765
• Oct4 Shuffles Sox Partners to Direct Cell Fate
  The EMBO Journal. Apr, 2013  |   Pubmed ID: 23474893
• The H3K27 Demethylase Utx Regulates Somatic and Germ Cell Epigenetic Reprogramming
  Nature. Aug, 2012  |   Pubmed ID: 22801502