Jacques Lapointe Department of Surgery, Division of Urology McGill University Biography Publications Institution JoVE Articles Jacques Lapointe has not added a biography. If you are Jacques Lapointe and would like to personalize this page please email our Author Liaison for assistance. Publications Interference Between Surgical Magnetic Drapes and Pacemakers: an Observational Study Comparing Commercially Available Devices and a New Magnetically Isolated Drape Biomedical Engineering Online. 2016 | Pubmed ID: 27430339 Cyclic Peptides Identified by Phage Display Are Competitive Inhibitors of the TRNA-dependent Amidotransferase of Helicobacter Pylori Peptides. May, 2016 | Pubmed ID: 26976271 Correction: TRNAGlu Increases the Affinity of Glutamyl-tRNA Synthetase for Its Inhibitor Glutamyl-Sulfamoyl-Adenosine, an Analogue of the Aminoacylation Reaction Intermediate Glutamyl-AMP: Mechanistic and Evolutionary Implications PloS One. 2015 | Pubmed ID: 26039673 TRNAGlu Increases the Affinity of Glutamyl-tRNA Synthetase for Its Inhibitor Glutamyl-sulfamoyl-adenosine, an Analogue of the Aminoacylation Reaction Intermediate Glutamyl-AMP: Mechanistic and Evolutionary Implications PloS One. 2015 | Pubmed ID: 25860020 Magnetic Interference of Cardiac Pacemakers from a Surgical Magnetic Drape Anesthesia and Analgesia. Mar, 2013 | Pubmed ID: 23400981 The 16p13.3 (PDPK1) Genomic Gain in Prostate Cancer: A Potential Role in Disease Progression Translational Oncology. Dec, 2012 | Pubmed ID: 23401739 PTEN Genomic Deletion Predicts Prostate Cancer Recurrence and is Associated with Low AR Expression and Transcriptional Activity BMC Cancer. 2012 | Pubmed ID: 23171135 Natural Insertion of the Bro-1 β-lactamase Gene into the GatCAB Operon Affects Moraxella Catarrhalis Aspartyl-tRNA(Asn) Amidotransferase Activity Microbiology (Reading, England). Sep, 2012 | Pubmed ID: 22745266 The Asparagine-transamidosome from Helicobacter Pylori: a Dual-kinetic Mode in Non-discriminating Aspartyl-tRNA Synthetase Safeguards the Genetic Code Nucleic Acids Research. Jun, 2012 | Pubmed ID: 22362756 Gln-tRNAGln Synthesis in a Dynamic Transamidosome from Helicobacter Pylori, Where GluRS2 Hydrolyzes Excess Glu-tRNAGln Nucleic Acids Research. Nov, 2011 | Pubmed ID: 21813455 A Tri-marker Proliferation Index Predicts Biochemical Recurrence After Surgery for Prostate Cancer PloS One. 2011 | Pubmed ID: 21629784 Inhibition of Helicobacter Pylori Aminoacyl-tRNA Amidotransferase by Chloramphenicol Analogs Bioorganic & Medicinal Chemistry. Nov, 2010 | Pubmed ID: 20943400 A C-truncated Glutamyl-tRNA Synthetase Specific for TRNA(Glu) is Stimulated by Its Free Complementary Distal Domain: Mechanistic and Evolutionary Implications Biochemistry. Jun, 2009 | Pubmed ID: 19496540 Peculiar Inhibition of Human Mitochondrial Aspartyl-tRNA Synthetase by Adenylate Analogs Biochimie. May, 2009 | Pubmed ID: 19254750 Identification of Candidate Prostate Cancer Genes Through Comparative Expression-profiling of Seminal Vesicle The Prostate. Aug, 2008 | Pubmed ID: 18500686 Inhibition of Helicobacter Pylori Aminoacyl-tRNA Amidotransferase by Puromycin Analogues Journal of the American Chemical Society. Mar, 2008 | Pubmed ID: 18293984 HCAP-D3 Expression Marks a Prostate Cancer Subtype with Favorable Clinical Behavior and Androgen Signaling Signature The American Journal of Surgical Pathology. Feb, 2008 | Pubmed ID: 18223322 Mechanism of a GatCAB Amidotransferase: Aspartyl-tRNA Synthetase Increases Its Affinity for Asp-tRNA(Asn) and Novel Aminoacyl-tRNA Analogues Are Competitive Inhibitors Biochemistry. Nov, 2007 | Pubmed ID: 17929881 Genomic Profiling Reveals Alternative Genetic Pathways of Prostate Tumorigenesis Cancer Research. Sep, 2007 | Pubmed ID: 17875689 E. Coli Glutamyl-tRNA Synthetase is Inhibited by Anticodon Stem-loop Domains and a Minihelix RNA Biology. Jul, 2007 | Pubmed ID: 17671438 Inhibition by L-aspartol Adenylate of a Nondiscriminating Aspartyl-tRNA Synthetase Reveals Differences Between the Interactions of Its Active Site with TRNA(Asp) and TRNA(Asn) Journal of Enzyme Inhibition and Medicinal Chemistry. Feb, 2007 | Pubmed ID: 17373551 A Variant TMPRSS2 Isoform and ERG Fusion Product in Prostate Cancer with Implications for Molecular Diagnosis Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Apr, 2007 | Pubmed ID: 17334351 Synthesis of Beta-ketophosphonate Analogs of Glutamyl and Glutaminyl Adenylate, and Selective Inhibition of the Corresponding Bacterial Aminoacyl-tRNA Synthetases Bioorganic & Medicinal Chemistry. Jan, 2007 | Pubmed ID: 17049867 Structural Bases of Transfer RNA-dependent Amino Acid Recognition and Activation by Glutamyl-tRNA Synthetase Structure (London, England : 1993). Dec, 2006 | Pubmed ID: 17161369 Application of Genomic Technologies to Human Prostate Cancer Omics : a Journal of Integrative Biology. 2006 | Pubmed ID: 17069507 Two Residues in the Anticodon Recognition Domain of the Aspartyl-tRNA Synthetase from Pseudomonas Aeruginosa Are Individually Implicated in the Recognition of TRNAAsn Journal of Bacteriology. Jan, 2006 | Pubmed ID: 16352843 The Retinoic Acid Synthesis Gene ALDH1a2 is a Candidate Tumor Suppressor in Prostate Cancer Cancer Research. Sep, 2005 | Pubmed ID: 16166285 Glu-Q-tRNA(Asp) Synthetase Coded by the YadB Gene, a New Paralog of Aminoacyl-tRNA Synthetase That Glutamylates TRNA(Asp) Anticodon Biochimie. Sep-Oct, 2005 | Pubmed ID: 16164993 Glutamylsulfamoyladenosine and Pyroglutamylsulfamoyladenosine Are Competitive Inhibitors of E. Coli Glutamyl-tRNA Synthetase Journal of Enzyme Inhibition and Medicinal Chemistry. Feb, 2005 | Pubmed ID: 15895686 Synthesis and Aminoacyl-tRNA Synthetase Inhibitory Activity of Aspartyl Adenylate Analogs Bioorganic & Medicinal Chemistry. Jan, 2005 | Pubmed ID: 15582453 Genome-wide Characterization of Gene Expression Variations and DNA Copy Number Changes in Prostate Cancer Cell Lines The Prostate. May, 2005 | Pubmed ID: 15486987 Crystal Structure of Chloramphenicol Acetyltransferase B2 Encoded by the Multiresistance Transposon Tn2424 Proteins. Dec, 2004 | Pubmed ID: 15390264 A Minimalist Glutamyl-tRNA Synthetase Dedicated to Aminoacylation of the TRNAAsp QUC Anticodon Nucleic Acids Research. 2004 | Pubmed ID: 15150343 An Aminoacyl-tRNA Synthetase-like Protein Encoded by the Escherichia Coli YadB Gene Glutamylates Specifically TRNAAsp Proceedings of the National Academy of Sciences of the United States of America. May, 2004 | Pubmed ID: 15096594 The Escherichia Coli YadB Gene Product Reveals a Novel Aminoacyl-tRNA Synthetase Like Activity Journal of Molecular Biology. Mar, 2004 | Pubmed ID: 15003446 The Zinc-binding Site of a Class I Aminoacyl-tRNA Synthetase is a SWIM Domain That Modulates Amino Acid Binding Via the TRNA Acceptor Arm European Journal of Biochemistry / FEBS. Feb, 2004 | Pubmed ID: 14764088 Direct Glutaminyl-tRNA Biosynthesis and Indirect Asparaginyl-tRNA Biosynthesis in Pseudomonas Aeruginosa PAO1 Journal of Bacteriology. Feb, 2004 | Pubmed ID: 14729703 Profil D'expression Génique Identifie Cliniquement Pertinentes Sous-types De Cancer De La Prostate Proceedings of the National Academy of Sciences of the United States of America. Jan, 2004 | Pubmed ID: 14711987 ATP Binding by Glutamyl-tRNA Synthetase is Switched to the Productive Mode by TRNA Binding The EMBO Journal. Feb, 2003 | Pubmed ID: 12554668 Préparation de Cores de tissus enrobés de paraffine fixés au formol pour les ARN et d'extraction d'ADN Palak G. Patel1,2, Shamini Selvarajah1,2, Suzanne Boursalie1,2, Nathan E. How1,2, Joshua Ejdelman3, Karl-Philippe Guerard3, John M. Bartlett4, Jacques Lapointe3, Paul C. Park1, John B. A. Okello1,2, David M. Berman1,2 1Department of Pathology & Molecular Medicine, Queen's University, 2Division of Cancer Biology & Genetics, Queen's Cancer Research Institute, Queen's University, 3Department of Surgery, Division of Urology, McGill University, 4Transformative Pathology Program, Ontario Institute for Cancer Research (OICR) Biology
Préparation de Cores de tissus enrobés de paraffine fixés au formol pour les ARN et d'extraction d'ADN Palak G. Patel1,2, Shamini Selvarajah1,2, Suzanne Boursalie1,2, Nathan E. How1,2, Joshua Ejdelman3, Karl-Philippe Guerard3, John M. Bartlett4, Jacques Lapointe3, Paul C. Park1, John B. A. Okello1,2, David M. Berman1,2 1Department of Pathology & Molecular Medicine, Queen's University, 2Division of Cancer Biology & Genetics, Queen's Cancer Research Institute, Queen's University, 3Department of Surgery, Division of Urology, McGill University, 4Transformative Pathology Program, Ontario Institute for Cancer Research (OICR) Biology