Jake A. Kushner Division of Endocrinology and Diabetes, Children’s Hospital of Philadelphia, Institute of Diabetes Obesity and Metabolism, Institute for Regenerative Medicine, Department of Pediatrics University of Pennsylvania-School of Medicine Biography Publications Institution JoVE Articles Jake A. Kushner has not added a biography. If you are Jake A. Kushner and would like to personalize this page please email our Author Liaison for assistance. Publications Glucose and Inflammation Control Islet Vascular Density and Beta-cell Function in NOD Mice: Control of Islet Vasculature and Vascular Endothelial Growth Factor by Glucose Diabetes. Mar, 2011 | Pubmed ID: 21307078 Aging Induces a Distinct Gene Expression Program in Mouse Islets Islets. Nov, 2010 | Pubmed ID: 21099336 Calcineurin Signaling Regulates Human Islet {beta}-cell Survival The Journal of Biological Chemistry. Dec, 2010 | Pubmed ID: 20943662 Ductal Origin Hypothesis of Pancreatic Regeneration Under Attack Cell Metabolism. Jan, 2010 | Pubmed ID: 20085728 Insulin-like Growth Factor 2 and the Insulin Receptor, but Not Insulin, Regulate Fetal Hepatic Glycogen Synthesis Endocrinology. Feb, 2010 | Pubmed ID: 20032056 Cyclin D2 Protein Stability is Regulated in Pancreatic Beta-cells Molecular Endocrinology (Baltimore, Md.). Nov, 2009 | Pubmed ID: 19628581 Adaptive Beta-cell Proliferation is Severely Restricted with Advanced Age Diabetes. Jun, 2009 | Pubmed ID: 19265026 Irs2 Inactivation Suppresses Tumor Progression in Pten+/- Mice The American Journal of Pathology. Jan, 2009 | Pubmed ID: 19095950 Beta-cell Mass and Type 1 Diabetes: Going, Going, Gone? Diabetes. Nov, 2008 | Pubmed ID: 18971435 Haematopoietic Stem Cells Do Not Asymmetrically Segregate Chromosomes or Retain BrdU Nature. Sep, 2007 | Pubmed ID: 17728714 Exendin-4 Improves Reversal of Diabetes in NOD Mice Treated with Anti-CD3 Monoclonal Antibody by Enhancing Recovery of Beta-cells Endocrinology. Nov, 2007 | Pubmed ID: 17673522 Identification of a WD40 Repeat-containing Isoform of PHIP As a Novel Regulator of Beta-cell Growth and Survival Molecular and Cellular Biology. Sep, 2007 | Pubmed ID: 17636024 Growth and Regeneration of Adult Beta Cells Does Not Involve Specialized Progenitors Developmental Cell. May, 2007 | Pubmed ID: 17488631 Autoimmunity and Beta Cell Regeneration in Mouse and Human Type 1 Diabetes: the Peace is Not Enough Annals of the New York Academy of Sciences. Apr, 2007 | Pubmed ID: 17376841 Effects of Autoimmunity and Immune Therapy on Beta-cell Turnover in Type 1 Diabetes Diabetes. Dec, 2006 | Pubmed ID: 17130466 Beta-cell Growth: an Unusual Paradigm of Organogenesis That is Cyclin D2/Cdk4 Dependent Cell Cycle (Georgetown, Tex.). Feb, 2006 | Pubmed ID: 16410729 Phosphatase and Tensin Homolog Regulation of Islet Growth and Glucose Homeostasis The Journal of Biological Chemistry. Nov, 2005 | Pubmed ID: 16170201 Very Slow Turnover of Beta-cells in Aged Adult Mice Diabetes. Sep, 2005 | Pubmed ID: 16123343 Cyclins D2 and D1 Are Essential for Postnatal Pancreatic Beta-cell Growth Molecular and Cellular Biology. May, 2005 | Pubmed ID: 15831479 Insulin Receptor Substrate 2 is Essential for Maturation and Survival of Photoreceptor Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2005 | Pubmed ID: 15689562 Dysregulation of Insulin Receptor Substrate 2 in Beta Cells and Brain Causes Obesity and Diabetes The Journal of Clinical Investigation. Oct, 2004 | Pubmed ID: 15467829 Effects of Dietary Glycaemic Index on Adiposity, Glucose Homoeostasis, and Plasma Lipids in Animals Lancet. Aug 28-Sep 3, 2004 | Pubmed ID: 15337404 Islet-sparing Effects of Protein Tyrosine Phosphatase-1b Deficiency Delays Onset of Diabetes in IRS2 Knockout Mice Diabetes. Jan, 2004 | Pubmed ID: 14693698 Insulin Receptor Substrate-2 Deficiency Impairs Brain Growth and Promotes Tau Phosphorylation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2003 | Pubmed ID: 12904469 Pdx1 Restores Beta Cell Function in Irs2 Knockout Mice The Journal of Clinical Investigation. May, 2002 | Pubmed ID: 11994408 مناعي الكشف عن النظائر ثيميدين الثاني (CldU وإيدو) في الأنسجة الابتدائية Alex H. Tuttle*1, Matthew M. Rankin*1, Monica Teta1, Daniel J. Sartori1, Geneva M. Stein1, Gina J. Kim1, Cristina Virgilio1, Anne Granger1, Di Zhou1, Simon H. Long1, Alisa B. Schiffman1, Jake A. Kushner1 1Division of Endocrinology and Diabetes, Children’s Hospital of Philadelphia, Institute of Diabetes Obesity and Metabolism, Institute for Regenerative Medicine, Department of Pediatrics, University of Pennsylvania-School of Medicine JoVE 2166 Biology
مناعي الكشف عن النظائر ثيميدين الثاني (CldU وإيدو) في الأنسجة الابتدائية Alex H. Tuttle*1, Matthew M. Rankin*1, Monica Teta1, Daniel J. Sartori1, Geneva M. Stein1, Gina J. Kim1, Cristina Virgilio1, Anne Granger1, Di Zhou1, Simon H. Long1, Alisa B. Schiffman1, Jake A. Kushner1 1Division of Endocrinology and Diabetes, Children’s Hospital of Philadelphia, Institute of Diabetes Obesity and Metabolism, Institute for Regenerative Medicine, Department of Pediatrics, University of Pennsylvania-School of Medicine JoVE 2166 Biology
