Jakub Fichna Department of Biochemistry, Faculty of Medicine Medical University of Lodz Biography Publications Institution JoVE Articles Jakub Fichna has not added a biography. If you are Jakub Fichna and would like to personalize this page please email our Author Liaison for assistance. Publications Cyclic Derivatives of Morphiceptin Possess Anti-transit Effect in the Gastrointestinal Tract and Alleviate Abdominal Pain in Mice Pharmacological Reports : PR. Mar, 2020 | Pubmed ID: 32125684 Biomarkers for Early Detection of Colitis-associated Colorectal Cancer - Current Concepts, Future Trends Current Drug Targets. Feb, 2020 | Pubmed ID: 32077822 Chemerin in Immune Response and Gastrointestinal Pathophysiology Clinica Chimica Acta; International Journal of Clinical Chemistry. May, 2020 | Pubmed ID: 32070869 Desensitization of Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel As Promising Therapy of Irritable Bowel Syndrome: Characterization of the Action of Palvanil in the Mouse Gastrointestinal Tract Naunyn-Schmiedeberg's Archives of Pharmacology. Jan, 2020 | Pubmed ID: 32002574 Opioids in Cancer Development, Progression and Metastasis: Focus on Colorectal Cancer Current Treatment Options in Oncology. Jan, 2020 | Pubmed ID: 31970561 [Strategies in Crohn's Disease Treatment - "step-up" Vs. "top-down"] Postepy Biochemii. Jan, 2020 | Pubmed ID: 31945286 Free Fatty Acid Receptors As New Potential Therapeutic Target in Inflammatory Bowel Diseases Pharmacological Research. Feb, 2020 | Pubmed ID: 31846762 Recent Advances in the Pharmacological Management of Constipation Predominant Irritable Bowel Syndrome Expert Opinion on Pharmacotherapy. Jan, 2020 | Pubmed ID: 31724881 Dietary Fatty Acid Content Influences the Expression of Genes Involved in the Lipid Turnover and Inflammation in Mouse Colon and Spleen Pharmacological Reports : PR. Sep, 2019 | Pubmed ID: 31994042 Biologic Therapy in Crohn's Disease - What We Learnt So Far Current Drug Targets. Dec, 2019 | Pubmed ID: 31854272 Gastrointestinal Adverse Events of Cannabinoid 1 Receptor Inverse Agonists Suggest Their Potential Use in Irritable Bowel Syndrome with Constipation: A Systematic Review and Meta-Analysis Journal of Gastrointestinal and Liver Diseases : JGLD. Dec, 2019 | Pubmed ID: 31826058 Free Fatty Acid Receptors As New Potential Target in Colorectal Cancer Current Drug Targets. 11, 2019 | Pubmed ID: 31721710 Chain Length of Dietary Fatty Acids Determines Gastrointestinal Motility and Visceromotor Function in Mice in a Fatty Acid Binding Protein 4-dependent Manner European Journal of Nutrition. Sep, 2019 | Pubmed ID: 31562532 Gut Microbiota: What is Its Place in Pharmacology? Expert Review of Clinical Pharmacology. Oct, 2019 | Pubmed ID: 31544557 Corrigendum to "Systemic Administration of Serotonin Exacerbates Abdominal Pain and Colitis Via Interaction with the Endocannabinoid System" [Biochem. Pharmacol. 161 (2019) 37-51] Biochemical Pharmacology. Nov, 2019 | Pubmed ID: 31526940 Corrigendum to "The Novel Peripherally Active Cannabinoid Type 1 and Serotonin Type 3 Receptor Agonist AM9405 Inhibits Gastrointestinal Motility and Reduces Abdominal Pain in Mouse Models Mimicking Irritable Bowel Syndrome" [Eur. J. Pharmacol. (2018), 836 34-43] European Journal of Pharmacology. Nov, 2019 | Pubmed ID: 31519354 Response to Lubiprostone in Chronic Constipation is Associated with Increased Mucus and Mucin Output: a Randomized Clinical Trial Journal of Gastrointestinal and Liver Diseases : JGLD. Sep, 2019 | Pubmed ID: 31517334 Organometallic Compounds and Metal Complexes in Current and Future Treatments of Inflammatory Bowel Disease and Colorectal Cancer-a Critical Review Biomolecules. 08, 2019 | Pubmed ID: 31443436 Evaluation of the Effect of Liposomes Loaded with Chlorogenic Acid in Treatment of 2,4,6-trinitrobenzenesulfonic Acid-induced Murine Colitis Journal of Physiology and Pharmacology : an Official Journal of the Polish Physiological Society. Apr, 2019 | Pubmed ID: 31443089 Dietary Fatty Acid Content Influences the Expression of Genes Involved in the Lipid Turnover and Inflammation in Mouse Colon and Spleen Pharmacological Reports : PR. Oct, 2019 | Pubmed ID: 31421543 Role of Glucagon-like Peptides in Inflammatory Bowel Diseases-current Knowledge and Future Perspectives Naunyn-Schmiedeberg's Archives of Pharmacology. 11, 2019 | Pubmed ID: 31359088 1-Substituted Sialorphin Analogues-synthesis, Molecular Modelling and in Vitro Effect on Enkephalins Degradation by NEP Amino Acids. Aug, 2019 | Pubmed ID: 31302778 Sex- and Age-Related Estrogen Signaling Alteration in Inflammatory Bowel Diseases: Modulatory Role of Estrogen Receptors International Journal of Molecular Sciences. Jun, 2019 | Pubmed ID: 31261736 Comparison of the Efficacy of Available Statistical Methods for Prediction of the Hospitalizations Number: Proof of Concept and Validation Based on the Analysis of Polish National Health Fund Data in the Years 2009-2017 Folia Medica Cracoviensia. 2019 | Pubmed ID: 31180078 Changes in the Diet Composition of Fatty Acids and Fiber Affect the Lower Gastrointestinal Motility but Have No Impact on Cardiovascular Parameters: In Vivo and in Vitro Studies Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 09, 2019 | Pubmed ID: 31145538 Effectiveness and Therapeutic Value of Phytochemicals in Acute Pancreatitis: A Review Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]. Jun, 2019 | Pubmed ID: 31079933 G Protein-coupled Estrogen Receptor Mediates Anti-inflammatory Action in Crohn's Disease Scientific Reports. May, 2019 | Pubmed ID: 31043642 Possible Application of Trefoil Factor Family Peptides in Gastroesophageal Reflux and Barrett's Esophagus Peptides. 05, 2019 | Pubmed ID: 30831146 High Activity of Endogenous Opioid System Protects Against Gastric Damage Development in Mouse Models of Gastric Mucosal Injury Pharmacological Reports : PR. Apr, 2019 | Pubmed ID: 30785059 Systemic Administration of Serotonin Exacerbates Abdominal Pain and Colitis Via Interaction with the Endocannabinoid System Biochemical Pharmacology. 03, 2019 | Pubmed ID: 30611738 Focus on Current and Future Management Possibilities in Inflammatory Bowel Disease-related Chronic Pain International Journal of Colorectal Disease. Feb, 2019 | Pubmed ID: 30564910 Enkephalinase Inhibitors, Potential Therapeutics for the Future Treatment of Diarrhea Predominant Functional Gastrointestinal Disorders Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 04, 2019 | Pubmed ID: 30549162 The Role of Adipose Tissue in the Pathogenesis of Crohn's Disease Pharmacological Reports : PR. Feb, 2019 | Pubmed ID: 30513401 Alterations of Colonic Sensitivity and Gastric Dysmotility After Acute Cisplatin and Granisetron Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 03, 2019 | Pubmed ID: 30402956 Enkephalin Degradation in Serum of Patients with Inflammatory Bowel Diseases Pharmacological Reports : PR. Feb, 2019 | Pubmed ID: 30391790 New Trends in Liposome-based Drug Delivery in Colorectal Cancer Mini Reviews in Medicinal Chemistry. 2019 | Pubmed ID: 30179131 High Activity of the Endogenous Opioid System and Acute but Not Chronic Stress Influence Experimental Colitis Development in Mice Journal of Physiology and Pharmacology : an Official Journal of the Polish Physiological Society. Oct, 2018 | Pubmed ID: 30683828 One Step Ahead: MiRNA-34 in Colon Cancer-future Diagnostic and Therapeutic Tool? Critical Reviews in Oncology/hematology. Dec, 2018 | Pubmed ID: 30447913 Young GI Angle: My Biggest (career) Mistake United European Gastroenterology Journal. Oct, 2018 | Pubmed ID: 30288292 Novel Peptide Inhibitor of Dipeptidyl Peptidase IV (Tyr-Pro-D-Ala-NH) with Anti-inflammatory Activity in the Mouse Models of Colitis Peptides. 10, 2018 | Pubmed ID: 30179653 Diagnostic Value of Chemerin in Lower Gastrointestinal Diseases-a Review Peptides. 10, 2018 | Pubmed ID: 30165089 The Novel Peripherally Active Cannabinoid Type 1 and Serotonin Type 3 Receptor Agonist AM9405 Inhibits Gastrointestinal Motility and Reduces Abdominal Pain in Mouse Models Mimicking Irritable Bowel Syndrome European Journal of Pharmacology. Oct, 2018 | Pubmed ID: 30121173 Genetic Molecular Subtypes in Optimizing Personalized Therapy for Metastatic Colorectal Cancer Current Drug Targets. 2018 | Pubmed ID: 30073926 Triphala: Current Applications and New Perspectives on the Treatment of Functional Gastrointestinal Disorders Chinese Medicine. 2018 | Pubmed ID: 30034512 Chronic Abdominal Pain in Irritable Bowel Syndrome - Current and Future Therapies Expert Review of Clinical Pharmacology. Jul, 2018 | Pubmed ID: 29957084 Inflammation-associated Changes in DOR Expression and Function in the Mouse Colon American Journal of Physiology. Gastrointestinal and Liver Physiology. 10, 2018 | Pubmed ID: 29927325 Bile Acids and FXR in Functional Gastrointestinal Disorders Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 08, 2018 | Pubmed ID: 29908754 Alanine Scan of Sialorphin and Its Hybrids with Opiorphin: Synthesis, Molecular Modelling and Effect on Enkephalins Degradation Amino Acids. Aug, 2018 | Pubmed ID: 29752565 Antinociceptive Potency of a Fluorinated Cyclopeptide Dmt-c[D-Lys-Phe-p-CF-Phe-Asp]NH Journal of Enzyme Inhibition and Medicinal Chemistry. Dec, 2018 | Pubmed ID: 29513114 Antinociceptive Potency of Enkephalins and Enkephalinase Inhibitors in the Mouse Model of Colorectal Distension-proof-of-concept Chemical Biology & Drug Design. 07, 2018 | Pubmed ID: 29495100 The Mechanisms Linking Obesity to Colon Cancer: An Overview Obesity Research & Clinical Practice. May - Jun, 2018 | Pubmed ID: 29428365 Novel Derivatives of 1,2,3-triazole, Cannabinoid-1 Receptor Ligands Modulate Gastrointestinal Motility in Mice Naunyn-Schmiedeberg's Archives of Pharmacology. 04, 2018 | Pubmed ID: 29404698 Evaluation of Melatonin Secretion and Metabolism Exponents in Patients with Ulcerative and Lymphocytic Colitis Molecules (Basel, Switzerland). Jan, 2018 | Pubmed ID: 29382152 Efficacy and Safety of Serotonin Receptor Ligands in the Treatment of Irritable Bowel Syndrome: A Review Current Drug Targets. 2018 | Pubmed ID: 29284389 Estrogen Signaling Deregulation Related with Local Immune Response Modulation in Irritable Bowel Syndrome Molecular and Cellular Endocrinology. 08, 2018 | Pubmed ID: 28774781 Development of the Rectal Dosage Form with Silver-coated Glass Beads for Local-action Applications in Lower Sections of the Gastrointestinal Tract Pharmaceutical Development and Technology. Mar, 2018 | Pubmed ID: 28756715 Evaluation of Anti-inflammatory Effect of Silver-coated Glass Beads in Mice with Experimentally Induced Colitis As a New Type of Treatment in Inflammatory Bowel Disease Pharmacological Reports : PR. May, 2017 | Pubmed ID: 31994113 Young GI Angle: The Role of Bibliometrics in Scientist's Career Development United European Gastroenterology Journal. Dec, 2017 | Pubmed ID: 29238594 Fat-soluble Vitamin Deficiencies and Inflammatory Bowel Disease: Systematic Review and Meta-Analysis Journal of Clinical Gastroenterology. Nov/Dec, 2017 | Pubmed ID: 28858940 Fatty Acid Amide Hydrolase (FAAH) Inhibitor PF-3845 Reduces Viability, Migration and Invasiveness of Human Colon Adenocarcinoma Colo-205 Cell Line: an in Vitro Study Acta Biochimica Polonica. 2017 | Pubmed ID: 28850633 Flavanols from Japanese Quince (Chaenomeles Japonica) Fruit Suppress Expression of Cyclooxygenase-2, Metalloproteinase-9, and Nuclear Factor-kappaB in Human Colon Cancer Cells Acta Biochimica Polonica. 2017 | Pubmed ID: 28787469 New Peptide Inhibitor of Dipeptidyl Peptidase IV, EMDB-1 Extends the Half-Life of GLP-2 and Attenuates Colitis in Mice After Topical Administration The Journal of Pharmacology and Experimental Therapeutics. 10, 2017 | Pubmed ID: 28724693 Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal Journal of Neurogastroenterology and Motility. Jul, 2017 | Pubmed ID: 28551943 Serum Cyclophilin A Correlates with Increased Tissue MMP-9 in Patients with Ulcerative Colitis, but Not with Crohn's Disease Digestive Diseases and Sciences. 06, 2017 | Pubmed ID: 28391416 Dual Functional Capability of Dendritic Cells - Cytokine-Induced Killer Cells in Improving Side Effects of Colorectal Cancer Therapy Frontiers in Pharmacology. 2017 | Pubmed ID: 28352234 Cannabinoid Receptor Type 1 and Mu-Opioid Receptor Polymorphisms Are Associated With Cyclic Vomiting Syndrome The American Journal of Gastroenterology. Jun, 2017 | Pubmed ID: 28349993 G Protein-Coupled Receptor 30 (GPR30) Expression Pattern in Inflammatory Bowel Disease Patients Suggests Its Key Role in the Inflammatory Process. A Preliminary Study Journal of Gastrointestinal and Liver Diseases : JGLD. Mar, 2017 | Pubmed ID: 28338111 G Protein-coupled Receptor 55 (GPR55) Expresses Differently in Patients with Crohn's Disease and Ulcerative Colitis Scandinavian Journal of Gastroenterology. Jun - Jul, 2017 | Pubmed ID: 28272905 Evaluation of Anti-inflammatory Effect of Silver-coated Glass Beads in Mice with Experimentally Induced Colitis As a New Type of Treatment in Inflammatory Bowel Disease Pharmacological Reports : PR. Jun, 2017 | Pubmed ID: 28267639 Future Treatment of Constipation-associated Disorders: Role of Relamorelin and Other Ghrelin Receptor Agonists Journal of Neurogastroenterology and Motility. Apr, 2017 | Pubmed ID: 28238253 Methyl-orvinol-Dual Activity Opioid Receptor Ligand Inhibits Gastrointestinal Transit and Alleviates Abdominal Pain in the Mouse Models Mimicking Diarrhea-predominant Irritable Bowel Syndrome Pharmacological Reports : PR. Apr, 2017 | Pubmed ID: 28187396 The Anti-Inflammatory Effect and Intestinal Barrier Protection of HU210 Differentially Depend on TLR4 Signaling in Dextran Sulfate Sodium-Induced Murine Colitis Digestive Diseases and Sciences. 02, 2017 | Pubmed ID: 27995407 Synthesis and Evaluation of Anti-inflammatory Properties of Silver Nanoparticle Suspensions in Experimental Colitis in Mice Chemical Biology & Drug Design. 04, 2017 | Pubmed ID: 27696734 Polyunsaturated Fatty Acids and Their Derivatives: Therapeutic Value for Inflammatory, Functional Gastrointestinal Disorders, and Colorectal Cancer Frontiers in Pharmacology. 2016 | Pubmed ID: 27990120 Anti-inflammatory Effect of Novel Analogs of Natural Enkephalinase Inhibitors in a Mouse Model of Experimental Colitis Future Medicinal Chemistry. 12, 2016 | Pubmed ID: 27845570 The Influence of Lipoic Acid on Caveolin-1-regulated Antioxidative Enzymes in the Mouse Model of Acute Ulcerative Colitis Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Dec, 2016 | Pubmed ID: 27685790 Alopecia Areata in Patients with Inflammatory Bowel Disease: an Overview Folia Medica Cracoviensia. 2016 | Pubmed ID: 27513834 Review: The Role of MOP and DOP Receptors in Treatment of Diarrheapredominant Irritable Bowel Syndrome Mini Reviews in Medicinal Chemistry. 2016 | Pubmed ID: 27494159 PhDs in Academic Gastroenterology: Key to a Successful Career United European Gastroenterology Journal. Jun, 2016 | Pubmed ID: 27403318 Elevated Risk of Venous Thromboembolic Events in Patients with Inflammatory Myopathies Vascular Health and Risk Management. 2016 | Pubmed ID: 27350751 Inflammatory Bowel Disease Treatment Pharmacological Reports : PR. Aug, 2016 | Pubmed ID: 27264361 Clinical Potential of Eluxadoline in the Treatment of Diarrhea-predominant Irritable Bowel Syndrome Therapeutics and Clinical Risk Management. 2016 | Pubmed ID: 27257381 Common Links Between Metabolic Syndrome and Inflammatory Bowel Disease: Current Overview and Future Perspectives Pharmacological Reports : PR. Aug, 2016 | Pubmed ID: 27238750 The Influence of Family Pattern Abnormalities in the Early Stages of Life on the Course of Inflammatory Bowel Diseases Pharmacological Reports : PR. Aug, 2016 | Pubmed ID: 27199029 Circadian Rhythm Abnormalities - Association with the Course of Inflammatory Bowel Disease Pharmacological Reports : PR. Aug, 2016 | Pubmed ID: 27166084 Pharmacology and Metabolism of Infliximab Biosimilars - A New Treatment Option in Inflammatory Bowel Diseases Pharmacological Reports : PR. Aug, 2016 | Pubmed ID: 27162107 Is Insulin-like Growth Factor 1 (IGF-1) System an Attractive Target Inflammatory Bowel Diseases? Benefits and Limitation of Potential Therapy Pharmacological Reports : PR. Aug, 2016 | Pubmed ID: 27117379 Inflammatory Bowel Diseases and Reproductive Health Pharmacological Reports : PR. Aug, 2016 | Pubmed ID: 27117378 LL-37: Cathelicidin-related Antimicrobial Peptide with Pleiotropic Activity Pharmacological Reports : PR. Aug, 2016 | Pubmed ID: 27117377 Anticonvulsant Activity of Melatonin, but Not Melatonin Receptor Agonists Neu-P11 and Neu-P67, in Mice Behavioural Brain Research. 07, 2016 | Pubmed ID: 27016427 Melatonin, but Not Melatonin Receptor Agonists Neu-P11 and Neu-P67, Attenuates TNBS-induced Colitis in Mice Naunyn-Schmiedeberg's Archives of Pharmacology. May, 2016 | Pubmed ID: 26899972 Neuropharmacological Characterization of the Oneirogenic Mexican Plant Calea Zacatechichi Aqueous Extract in Mice Metabolic Brain Disease. 06, 2016 | Pubmed ID: 26821073 Anemia of Chronic Disease and Iron Deficiency Anemia in Inflammatory Bowel Diseases: Pathophysiology, Diagnosis, and Treatment Inflammatory Bowel Diseases. May, 2016 | Pubmed ID: 26818422 RGS Proteins As Targets in the Treatment of Intestinal Inflammation and Visceral Pain: New Insights and Future Perspectives BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Apr, 2016 | Pubmed ID: 26817719 Enhancement of Anticancer Potential of Polyphenols by Covalent Modifications Biochemical Pharmacology. 06, 2016 | Pubmed ID: 26776305 Novel Investigational Drugs for Constipation-predominant Irritable Bowel Syndrome: a Review Expert Opinion on Investigational Drugs. 2016 | Pubmed ID: 26765585 Mixed MOP/DOP Agonist Biphalin Elicits Anti-transit Effect in Mouse Models Mimicking Diarrhea-predominant Irritable Bowel Syndrome Symptoms Pharmacological Reports : PR. Feb, 2016 | Pubmed ID: 26721348 Expression and Physiology of Opioid Receptors in the Gastrointestinal Tract Current Opinion in Endocrinology, Diabetes, and Obesity. Feb, 2016 | Pubmed ID: 26702845 Encenicline, an α7 Nicotinic Acetylcholine Receptor Partial Agonist, Reduces Immune Cell Infiltration in the Colon and Improves Experimental Colitis in Mice The Journal of Pharmacology and Experimental Therapeutics. Jan, 2016 | Pubmed ID: 26462538 Mean Platelet Volume in Crohn's Disease Patients Predicts Sustained Response to a 52-Week Infliximab Therapy: A Pilot Study Digestive Diseases and Sciences. Feb, 2016 | Pubmed ID: 26441277 Rhenium-coated Glass Beads for Intracolonic Administration Attenuate TNBS-induced Colitis in Mice: Proof-of-Concept Study Folia Medica Cracoviensia. 2015 | Pubmed ID: 26867119 Berberine Improves Intestinal Motility and Visceral Pain in the Mouse Models Mimicking Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) Symptoms in an Opioid-Receptor Dependent Manner PloS One. 2015 | Pubmed ID: 26700862 Role of Environmental Pollution in Irritable Bowel Syndrome World Journal of Gastroenterology. Oct, 2015 | Pubmed ID: 26523104 Silver and Other Metals in the Treatment of Gastrointestinal Diseases Current Medicinal Chemistry. 2015 | Pubmed ID: 26423087 Anti-inflammatory Effect of Dual Nociceptin and Opioid Receptor Agonist, BU08070, in Experimental Colitis in Mice European Journal of Pharmacology. Oct, 2015 | Pubmed ID: 26404500 A Randomized Clinical Trial of Berberine Hydrochloride in Patients with Diarrhea-Predominant Irritable Bowel Syndrome Phytotherapy Research : PTR. Nov, 2015 | Pubmed ID: 26400188 The Role of AST-120 and Protein-bound Uremic Toxins in Irritable Bowel Syndrome: a Therapeutic Perspective Therapeutic Advances in Gastroenterology. Sep, 2015 | Pubmed ID: 26327918 Comment on Choi Et Al.: High-fat Diet Decreases Energy Expenditure and Expression of Genes Controlling Lipid Metabolism, Mitochondrial Function and Skeletal System Development in the Adipose Tissue, Along with Increased Expression of Extracellular Matrix Remodelling- and Inflammation-related Genes The British Journal of Nutrition. Aug, 2015 | Pubmed ID: 26277837 Nociceptin Effect on Intestinal Motility Depends on Opioid-receptor Like-1 Receptors and Nitric Oxide Synthase Co-localization World Journal of Gastrointestinal Pharmacology and Therapeutics. Aug, 2015 | Pubmed ID: 26261735 Cannabinoids Regulate Intestinal Motor Function and Electrophysiological Activity of Myocytes in Rodents Archives of Medical Research. Aug, 2015 | Pubmed ID: 26254701 Polyphenols As Mitochondria-targeted Anticancer Drugs Cancer Letters. Oct, 2015 | Pubmed ID: 26185003 Inhibition of Ileal Bile Acid Transporter: An Emerging Therapeutic Strategy for Chronic Idiopathic Constipation World Journal of Gastroenterology. Jun, 2015 | Pubmed ID: 26139989 Tenapanor Hydrochloride for the Treatment of Constipation-predominant Irritable Bowel Syndrome Expert Opinion on Investigational Drugs. 2015 | Pubmed ID: 26065434 Neutrophil-lymphocyte Ratio in Crohn's Disease Patients Predicts Sustained Response to Infliximab 52-week Therapy Journal of Gastrointestinal and Liver Diseases : JGLD. Mar, 2015 | Pubmed ID: 25822447 Beneficial Effects of Probiotics, Prebiotics, Synbiotics, and Psychobiotics in Inflammatory Bowel Disease Inflammatory Bowel Diseases. Jul, 2015 | Pubmed ID: 25822014 The Link Between Cardiovascular and Circulatory Events in Inflammatory Gastrointestinal Disorders Current Drug Targets. 2015 | Pubmed ID: 25780932 Experimental Colitis in Mice is Attenuated by Topical Administration of Chlorogenic Acid Naunyn-Schmiedeberg's Archives of Pharmacology. Jun, 2015 | Pubmed ID: 25743575 Ischemic Colitis: Current Diagnosis and Treatment Current Drug Targets. 2015 | Pubmed ID: 25585127 Orally Administered Novel Cyclic Pentapeptide P-317 Alleviates Symptoms of Diarrhoea-predominant Irritable Bowel Syndrome The Journal of Pharmacy and Pharmacology. Feb, 2015 | Pubmed ID: 25515402 Role of G Protein-coupled Orphan Receptors in Intestinal Inflammation: Novel Targets in Inflammatory Bowel Diseases Inflammatory Bowel Diseases. Mar, 2015 | Pubmed ID: 25461621 Role of Transient Receptor Potential Channels in Intestinal Inflammation and Visceral Pain: Novel Targets in Inflammatory Bowel Diseases Inflammatory Bowel Diseases. Feb, 2015 | Pubmed ID: 25437822 Prevention and Therapeutic Strategies of Thromboembolic Events in Patients with Inflammatory Bowel Diseases: a Report of Three Cases Current Drug Targets. 2015 | Pubmed ID: 25382207 What is the Future of the Gut Microbiota-Related Treatment? Toward Modulation of Microbiota in Preventive and Therapeutic Medicine Frontiers in Medicine. 2014 | Pubmed ID: 25705630 Comment on "Intestinal Inflammation Modulates Expression of the Iron-regulating Hormone Hepcidin Depending on Erythropoietic Activity and the Commensal Microbiota" Journal of Immunology (Baltimore, Md. : 1950). Dec, 2014 | Pubmed ID: 25480953 Cannabinoids Alleviate Experimentally Induced Intestinal Inflammation by Acting at Central and Peripheral Receptors PloS One. 2014 | Pubmed ID: 25275313 Novel Orally Available Salvinorin A Analog PR-38 Protects Against Experimental Colitis and Reduces Abdominal Pain in Mice by Interaction with Opioid and Cannabinoid Receptors Biochemical Pharmacology. Dec, 2014 | Pubmed ID: 25265540 Anti-inflammatory and Antinociceptive Action of the Dimeric Enkephalin Peptide Biphalin in the Mouse Model of Colitis: New Potential Treatment of Abdominal Pain Associated with Inflammatory Bowel Diseases Peptides. Oct, 2014 | Pubmed ID: 25151037 Current Overview of Extrinsic and Intrinsic Factors in Etiology and Progression of Inflammatory Bowel Diseases Pharmacological Reports : PR. Oct, 2014 | Pubmed ID: 25149979 Anti-inflammatory Action of a Novel Orally Available Peptide 317 in Mouse Models of Inflammatory Bowel Diseases Pharmacological Reports : PR. Oct, 2014 | Pubmed ID: 25149976 Cross-talk Between Serotonin and Cannabinoid Signaling in the Gut, New Insights and Future Perspectives Pain. Oct, 2014 | Pubmed ID: 25109671 Antinociceptive and Antidepressant-like Action of Endomorphin-2 Analogs with Proline Surrogates in Position 2 Bioorganic & Medicinal Chemistry. Sep, 2014 | Pubmed ID: 25047937 Correlations Between Skin Lesions Induced by Anti-tumor Necrosis Factor-α and Selected Cytokines in Crohn's Disease Patients World Journal of Gastroenterology. Jun, 2014 | Pubmed ID: 24944497 Novel Mixed NOP/MOP Agonist BU08070 Alleviates Pain and Inhibits Gastrointestinal Motility in Mouse Models Mimicking Diarrhea-predominant Irritable Bowel Syndrome Symptoms European Journal of Pharmacology. Aug, 2014 | Pubmed ID: 24815321 Review Article: the Role of Oxidative Stress in Pathogenesis and Treatment of Inflammatory Bowel Diseases Naunyn-Schmiedeberg's Archives of Pharmacology. Jul, 2014 | Pubmed ID: 24798211 Chinese Herbal Medicines in the Treatment of IBD and Colorectal Cancer: a Review Current Treatment Options in Oncology. Sep, 2014 | Pubmed ID: 24792017 Antinociceptive Effects of Novel Melatonin Receptor Agonists in Mouse Models of Abdominal Pain World Journal of Gastroenterology. Feb, 2014 | Pubmed ID: 24574803 Anti-inflammatory and Antinociceptive Action of an Orally Available Nociceptin Receptor Agonist SCH 221510 in a Mouse Model of Inflammatory Bowel Diseases The Journal of Pharmacology and Experimental Therapeutics. Mar, 2014 | Pubmed ID: 24345466 Inhibition of Fatty Acid Amide Hydrolase (FAAH) As a Novel Therapeutic Strategy in the Treatment of Pain and Inflammatory Diseases in the Gastrointestinal Tract European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Feb, 2014 | Pubmed ID: 24275607 Pharmacological Properties of Novel Cyclic Pentapeptides with µ-opioid Receptor Agonist Activity Medicinal Chemistry (Shariqah (United Arab Emirates)). Mar, 2014 | Pubmed ID: 23628088 Physiology, Signaling, and Pharmacology of Opioid Receptors and Their Ligands in the Gastrointestinal Tract: Current Concepts and Future Perspectives Journal of Gastroenterology. Jan, 2014 | Pubmed ID: 23397116 Endocannabinoid and Cannabinoid-like Fatty Acid Amide Levels Correlate with Pain-related Symptoms in Patients with IBS-D and IBS-C: a Pilot Study PloS One. 2013 | Pubmed ID: 24386448 Novel Glycosylated Endomorphin-2 Analog Produces Potent Centrally-mediated Antinociception in Mice After Peripheral Administration Bioorganic & Medicinal Chemistry Letters. Dec, 2013 | Pubmed ID: 24220171 Nociceptin / Orphanin FQ (NOP) Receptors As Novel Potential Target in the Treatment of Gastrointestinal Diseases Current Drug Targets. Sep, 2013 | Pubmed ID: 23773151 A Role for O-1602 and G Protein-coupled Receptor GPR55 in the Control of Colonic Motility in Mice Neuropharmacology. Aug, 2013 | Pubmed ID: 23603203 Inhibition of Proteases As a Novel Therapeutic Strategy in the Treatment of Metabolic, Inflammatory and Functional Diseases of the Gastrointestinal Tract Drug Discovery Today. Aug, 2013 | Pubmed ID: 23567293 The Mu-opioid Receptor-selective Peptide Antagonists, Antanal-1 and Antanal-2, Produce Anticonvulsant Effects in Mice Progress in Neuro-psychopharmacology & Biological Psychiatry. Jan, 2013 | Pubmed ID: 22918032 Non-specific Abdominal Pain and Air Pollution: a Novel Association PloS One. 2012 | Pubmed ID: 23118887 Brain-Gut Interactions in IBS Frontiers in Pharmacology. 2012 | Pubmed ID: 22783191 Kinetic Studies of Novel Inhibitors of Endomorphin Degrading Enzymes Medicinal Chemistry Research : an International Journal for Rapid Communications on Design and Mechanisms of Action of Biologically Active Agents. Jul, 2012 | Pubmed ID: 22707871 Natural and Synthetic α-methylenelactones and α-methylenelactams with Anticancer Potential Drug Discovery Today. Jun, 2012 | Pubmed ID: 22309965 Effect of 2',6'-dimethyl-L-tyrosine (Dmt) on Pharmacological Activity of Cyclic Endomorphin-2 and Morphiceptin Analogs Bioorganic & Medicinal Chemistry. Dec, 2011 | Pubmed ID: 22047797 The Role of Morphine in Regulation of Cancer Cell Growth Naunyn-Schmiedeberg's Archives of Pharmacology. Sep, 2011 | Pubmed ID: 21800094 Synthesis and Biological Evaluation of New Salvinorin A Analogues Incorporating Natural Amino Acids Bioorganic & Medicinal Chemistry Letters. Jan, 2011 | Pubmed ID: 21115248 Synthesis and Biological Evaluation of Novel Peripherally Active Morphiceptin Analogs Peptides. Aug, 2010 | Pubmed ID: 20434497 Selective Natural Kappa Opioid and Cannabinoid Receptor Agonists with a Potential Role in the Treatment of Gastrointestinal Dysfunction Drug News & Perspectives. Sep, 2009 | Pubmed ID: 19890495 The Influence of Opioids on Urokinase Plasminogen Activator on Protein and MRNA Level in MCF-7 Breast Cancer Cell Line Chemical Biology & Drug Design. Oct, 2009 | Pubmed ID: 19691469 Biological Activity of Endomorphin and [Dmt1]endomorphin Analogs with Six-membered Proline Surrogates in Position 2 Bioorganic & Medicinal Chemistry. Jun, 2009 | Pubmed ID: 19435668 Opioid Antagonist-induced Regulation of the Mu-opioid Receptor Expression in MCF-7 Breast Cancer Cell Line Endocrine Regulations. Jan, 2009 | Pubmed ID: 19309235 Enzymatic Degradation of Endomorphins Peptides. Nov, 2008 | Pubmed ID: 18718496 Opioid-induced Regulation of Mu-opioid Receptor Gene Expression in the MCF-7 Breast Cancer Cell Line Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Jun, 2008 | Pubmed ID: 18523482 [Dmt1, D-1-Nal3]morphiceptin, a Novel Opioid Peptide Analog with High Analgesic Activity Peptides. Apr, 2008 | Pubmed ID: 18234394 Novel Highly Potent Mu-opioid Receptor Antagonist Based on Endomorphin-2 Structure Bioorganic & Medicinal Chemistry Letters. Feb, 2008 | Pubmed ID: 18207400 Antidepressant-like Effect of Endomorphin-1 and Endomorphin-2 in Mice Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Apr, 2007 | Pubmed ID: 16823383 [Opioid Receptors and Their Selective Ligands] Postepy Biochemii. 2006 | Pubmed ID: 17201067 Characterization of Tachykinin-related Peptides from Different Insect Species on Drosophila Tachykinin Receptor-expressing Cell Line Chemical Biology & Drug Design. Nov, 2006 | Pubmed ID: 17177889 In Vitro Characterization of Novel Peptide Inhibitors of Endomorphin-degrading Enzymes in the Rat Brain Chemical Biology & Drug Design. Sep, 2006 | Pubmed ID: 17062015 [D-1-Nal4]endomorphin-2 is a Potent Micro-opioid Receptor Antagonist in the Aequorin Luminescence-based Calcium Assay Life Sciences. Aug, 2006 | Pubmed ID: 16624333 Functional Characterization of Opioid Receptor Ligands by Aequorin Luminescence-based Calcium Assay The Journal of Pharmacology and Experimental Therapeutics. Jun, 2006 | Pubmed ID: 16497786 Enzymatic Degradation Studies of Endomorphin-2 and Its Analogs Containing N-methylated Amino Acids Peptides. Jan, 2006 | Pubmed ID: 16087275 Synthesis and Antinociceptive Activity of Cyclic Endomorphin-2 and Morphiceptin Analogs Biochemical Pharmacology. Dec, 2005 | Pubmed ID: 16288997 Comparison of Antagonist Activity of Spantide Family at Human Neurokinin Receptors Measured by Aequorin Luminescence-based Functional Calcium Assay Regulatory Peptides. Nov, 2005 | Pubmed ID: 15990182 Inhibition of Trigemino-hypoglossal Reflex in Rats by Oxytocin is Mediated by Mu and Kappa Opioid Receptors Brain Research. Feb, 2005 | Pubmed ID: 15713278 Characterization of the [125I]endomorphin-2 Binding Sites in the MCF7 Breast Cancer Cell Line Peptides. Feb, 2005 | Pubmed ID: 15629541 Characterization of Antinociceptive Activity of Novel Endomorphin-2 and Morphiceptin Analogs Modified in the Third Position Biochemical Pharmacology. Jan, 2005 | Pubmed ID: 15588726 Opioid Peptides in Cancer Cancer Metastasis Reviews. Aug-Dec, 2004 | Pubmed ID: 15197335 Opioid Receptors and Their Ligands Current Topics in Medicinal Chemistry. 2004 | Pubmed ID: 14754373 Synthesis of Target-specific Radiolabeled Peptides for Diagnostic Imaging Bioconjugate Chemistry. Jan-Feb, 2003 | Pubmed ID: 12526687 Structure-activity Relationship, Conformation and Pharmacology Studies of Morphiceptin Analogues--selective Mu-opioid Receptor Ligands Mini Reviews in Medicinal Chemistry. Dec, 2002 | Pubmed ID: 12370041 Visualisatie van oestrogeenreceptoren in colons van muizen met tnbs-geïnduceerde ziekte van Crohn met behulp van immunofluorescentie Damian Jacenik1, Marta Zielińska2, Sylwia Michlewska3, Jakub Fichna2, Wanda M. Krajewska1 1Department of Cytobiochemistry, Faculty of Biology and Environmental Protection, University of Lodz, 2Department of Biochemistry, Faculty of Medicine, Medical University of Lodz, 3Laboratory of Microscopic Imaging and Specialized Biological Techniques, Faculty of Biology and Environmental Protection, University of Lodz JoVE 60813 Biochemistry
Visualisatie van oestrogeenreceptoren in colons van muizen met tnbs-geïnduceerde ziekte van Crohn met behulp van immunofluorescentie Damian Jacenik1, Marta Zielińska2, Sylwia Michlewska3, Jakub Fichna2, Wanda M. Krajewska1 1Department of Cytobiochemistry, Faculty of Biology and Environmental Protection, University of Lodz, 2Department of Biochemistry, Faculty of Medicine, Medical University of Lodz, 3Laboratory of Microscopic Imaging and Specialized Biological Techniques, Faculty of Biology and Environmental Protection, University of Lodz JoVE 60813 Biochemistry
