James E. Klaunig School of Public Health Indiana University Biography Publications Institution JoVE Articles James E. Klaunig has not added a biography. If you are James E. Klaunig and would like to personalize this page please email our Author Liaison for assistance. Publications Icariin Protects Rotenone-induced Neurotoxicity Through Induction of SIRT3 Toxicology and Applied Pharmacology. Sep, 2019 | Pubmed ID: 31251943 The Effects of Perfluorooctanoate on High Fat Diet Induced Non-alcoholic Fatty Liver Disease in Mice Toxicology. Mar, 2019 | Pubmed ID: 30711707 Editorial Regulatory Toxicology and Pharmacology : RTP. 02, 2019 | Pubmed ID: 30642615 A Simple Automated Method for Continuous Fieldwise Measurement of Microvascular Hemodynamics Microvascular Research. 05, 2019 | Pubmed ID: 30502365 Oxidative Stress and Cancer Current Pharmaceutical Design. 2018 | Pubmed ID: 30767733 Modeling of Xenobiotic Transport and Metabolism in Virtual Hepatic Lobule Models PloS One. 2018 | Pubmed ID: 30212461 Modulation of Xenobiotic Nuclear Receptors in High-fat Diet Induced Non-alcoholic Fatty Liver Disease Toxicology. 12, 2018 | Pubmed ID: 30120929 Role of Xenobiotics in the Induction and Progression of Fatty Liver Disease Toxicology Research. Jul, 2018 | Pubmed ID: 30090613 Obfuscating Transparency? Regulatory Toxicology and Pharmacology : RTP. Aug, 2018 | Pubmed ID: 30017904 Effect of Polyhexamethylene Biguanide on Rat Liver Toxicology Letters. Mar, 2018 | Pubmed ID: 29305328 Autophagy Plays a Protective Role in Mn-induced Toxicity in PC12 Cells Toxicology. 02, 2018 | Pubmed ID: 29222055 The PPARα-dependent Rodent Liver Tumor Response is Not Relevant to Humans: Addressing Misconceptions Archives of Toxicology. Jan, 2018 | Pubmed ID: 29197930 Human Relevance of Rodent Liver Tumors: Key Insights from a Toxicology Forum Workshop on Nongenotoxic Modes of Action Regulatory Toxicology and Pharmacology : RTP. Feb, 2018 | Pubmed ID: 29113941 Comments on the Safety Assessment of Decamethylcyclopentasiloxane (D5) Published in Regulatory Toxicology and Pharmacology, 2017, 83:117-118 Regulatory Toxicology and Pharmacology : RTP. 10, 2017 | Pubmed ID: 28780200 Induction of Endogenous Retroelements As a Potential Mechanism for Mouse-specific Drug-induced Carcinogenicity PloS One. 2017 | Pubmed ID: 28472135 Investigation of the Mechanism of Triclosan Induced Mouse Liver Tumors Regulatory Toxicology and Pharmacology : RTP. Jun, 2017 | Pubmed ID: 28267557 Toxaphene-induced Mouse Liver Tumorigenesis is Mediated by the Constitutive Androstane Receptor Journal of Applied Toxicology : JAT. 08, 2017 | Pubmed ID: 28218408 Biological Relevance of Effects Following Chronic Administration of Octamethylcyclotetrasiloxane (D4) in Fischer 344 Rats Toxicology Letters. Oct, 2017 | Pubmed ID: 28109826 Response to Druwe and Burgoon, 2016 Letter to the Editor in Archives of Toxicology Archives of Toxicology. 02, 2017 | Pubmed ID: 27830267 Upholding Science in Health, Safety and Environmental Risk Assessments and Regulations Toxicology. Sep, 2016 | Pubmed ID: 27639665 Whither the Impending European Regulation of Presumed Endocrine Disruptors? Regulatory Toxicology and Pharmacology : RTP. Dec, 2016 | Pubmed ID: 27615676 Response to Druwe and Burgoon : Re: Druwe, I.L. and Burgoon, L.: Revisiting Cohen Et Al. 2015, Cohen Et Al. 2014 and Waalkes Et Al. 2014: a Bayesian Re-analysis of Tumor Incidences Archives of Toxicology. 12, 2016 | Pubmed ID: 27542124 A Randomized Placebo-controlled Pilot Study of N-acetylcysteine in Youth with Autism Spectrum Disorder Molecular Autism. 2016 | Pubmed ID: 27103982 Cryopreservation of Human Blood for Alkaline and Fpg-modified Comet Assay Toxicology Mechanisms and Methods. 2016 | Pubmed ID: 26982377 Protective Effects of Antioxidants on Acrylonitrile-induced Oxidative Stress in Female F344 Rats Environmental Toxicology. Dec, 2016 | Pubmed ID: 26332274 Biological Relevance of Decamethylcyclopentasiloxane (D5) Induced Rat Uterine Endometrial Adenocarcinoma Tumorigenesis: Mode of Action and Relevance to Humans Regulatory Toxicology and Pharmacology : RTP. Feb, 2016 | Pubmed ID: 26148665 Toxicology of Decamethylcyclopentasiloxane (D5) Regulatory Toxicology and Pharmacology : RTP. Feb, 2016 | Pubmed ID: 26111607 Alkaline Comet Assay for Assessing DNA Damage in Individual Cells Current Protocols in Toxicology. Aug, 2015 | Pubmed ID: 26250399 Mechanistic Investigation of Toxaphene Induced Mouse Liver Tumors Toxicological Sciences : an Official Journal of the Society of Toxicology. Oct, 2015 | Pubmed ID: 26187448 The Potential for Chemical Mixtures from the Environment to Enable the Cancer Hallmark of Sustained Proliferative Signalling Carcinogenesis. Jun, 2015 | Pubmed ID: 26106143 Assessing the Carcinogenic Potential of Low-dose Exposures to Chemical Mixtures in the Environment: the Challenge Ahead Carcinogenesis. Jun, 2015 | Pubmed ID: 26106142 Antioxidant Vitamin C Prevents Decline in Endothelial Function During Sitting Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. Apr, 2015 | Pubmed ID: 25848890 Evaluation of the Chronic Toxicity and Carcinogenicity of Perfluorohexanoic Acid (PFHxA) in Sprague-Dawley Rats Toxicologic Pathology. Feb, 2015 | Pubmed ID: 25377447 Mechanism of 1,3-dichloropropene-induced Rat Liver Carcinogenesis Toxicological Sciences : an Official Journal of the Society of Toxicology. Jan, 2015 | Pubmed ID: 25354764 Development of a Cytokine-producing Immortalized Murine Kupffer Cell Line Cytokine. Dec, 2014 | Pubmed ID: 25138015 Evaluating Uncertainty to Strengthen Epidemiologic Data for Use in Human Health Risk Assessments Environmental Health Perspectives. Nov, 2014 | Pubmed ID: 25079138 Contribution of Environment and Genetics to Pancreatic Cancer Susceptibility PloS One. 2014 | Pubmed ID: 24651674 Caenorhabditis Elegans Neuron Degeneration and Mitochondrial Suppression Caused by Selected Environmental Chemicals International Journal of Biochemistry and Molecular Biology. 2013 | Pubmed ID: 24380023 Alterations in Brain Structure and Function in Breast Cancer Survivors: Effect of Post-chemotherapy Interval and Relation to Oxidative DNA Damage Breast Cancer Research and Treatment. Jan, 2013 | Pubmed ID: 23263697 Mode of Action Analysis of Perfluorooctanoic Acid (PFOA) Tumorigenicity and Human Relevance Reproductive Toxicology (Elmsford, N.Y.). Jul, 2012 | Pubmed ID: 22120428 Oxidative Stress in Chronic Liver Disease: Relationship Between Peripheral and Hepatic Measurements The American Journal of the Medical Sciences. Oct, 2011 | Pubmed ID: 21691193 Dose-related Induction of Hepatic Preneoplastic Lesions by Diethylnitrosamine in C57BL/6 Mice Toxicologic Pathology. Aug, 2011 | Pubmed ID: 21628716 Oxidative Stress and Oxidative Damage in Chemical Carcinogenesis Toxicology and Applied Pharmacology. Jul, 2011 | Pubmed ID: 21296097 Effect of Different Obesogenic Diets on Pancreatic Histology in Ossabaw Miniature Swine Pancreas. Apr, 2011 | Pubmed ID: 21240032 Linear Low-dose Extrapolation for Noncancer Heath Effects is the Exception, Not the Rule Critical Reviews in Toxicology. Jan, 2011 | Pubmed ID: 21226629 Conditional Beta-catenin Loss in Mice Promotes Chemical Hepatocarcinogenesis: Role of Oxidative Stress and Platelet-derived Growth Factor Receptor Alpha/phosphoinositide 3-kinase Signaling Hepatology (Baltimore, Md.). Sep, 2010 | Pubmed ID: 20583210 Kupffer Cells Participate in 2-butoxyethanol-induced Liver Hemangiosarcomas Toxicology. Apr, 2010 | Pubmed ID: 20153399 Oxidative Stress and Oxidative Damage in Carcinogenesis Toxicologic Pathology. Jan, 2010 | Pubmed ID: 20019356 Assessment of Gap Junctional Intercellular Communication Current Protocols in Toxicology. Aug, 2009 | Pubmed ID: 20941698 Acrylonitrile-induced Oxidative Stress and Oxidative DNA Damage in Male Sprague-Dawley Rats Toxicological Sciences : an Official Journal of the Society of Toxicology. Sep, 2009 | Pubmed ID: 19546159 Nutritional Model of Steatohepatitis and Metabolic Syndrome in the Ossabaw Miniature Swine Hepatology (Baltimore, Md.). Jul, 2009 | Pubmed ID: 19434740 Effect of Oral Methyl-t-butyl Ether (MTBE) on the Male Mouse Reproductive Tract and Oxidative Stress in Liver Reproductive Toxicology (Elmsford, N.Y.). Nov-Dec, 2008 | Pubmed ID: 18824092 Remembering Benjamin Franklin Trump Veterinary Pathology. Sep, 2008 | Pubmed ID: 18725462 Acrylamide Carcinogenicity Journal of Agricultural and Food Chemistry. Aug, 2008 | Pubmed ID: 18624430 Oxidative Status in Neuroblastoma: a Source of Stress? Journal of Pediatric Surgery. Feb, 2008 | Pubmed ID: 18280284 Constitutional Polymorphisms of Prostate Cancer: Prognostic and Diagnostic Implications Future Oncology (London, England). Dec, 2007 | Pubmed ID: 18041919 PPARalpha and Effects of TCE Environmental Health Perspectives. Jan, 2007 | Pubmed ID: 17366801 Acrylonitrile-induced Oxidative DNA Damage in Rat Astrocytes Environmental and Molecular Mutagenesis. Oct, 2006 | Pubmed ID: 16917936 Mechanisms of 2-butoxyethanol-induced Hemangiosarcomas Toxicological Sciences : an Official Journal of the Society of Toxicology. Aug, 2006 | Pubmed ID: 16675516 Mechanisms of Acrylamide Induced Rodent Carcinogenesis Advances in Experimental Medicine and Biology. 2005 | Pubmed ID: 16438288 Cancer Biology and Hormesis: Commentary Critical Reviews in Toxicology. Jul, 2005 | Pubmed ID: 16422395 Indinavir Impairs Endothelial Function in Healthy HIV-negative Men American Heart Journal. Nov, 2005 | Pubmed ID: 16290967 Species Differences in the Induction of Hepatocellular DNA Synthesis by Diethanolamine Toxicological Sciences : an Official Journal of the Society of Toxicology. Oct, 2005 | Pubmed ID: 16014740 Subchronic Acrylamide Treatment Induces a Tissue-specific Increase in DNA Synthesis in the Rat Toxicology Letters. Dec, 2004 | Pubmed ID: 15475183 The Effects of Ecstasy (MDMA) on Rat Liver Bioenergetics Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine. Jul, 2004 | Pubmed ID: 15231458 The Role of Oxidative Stress in Carcinogenesis Annual Review of Pharmacology and Toxicology. 2004 | Pubmed ID: 14744246 PPARalpha Agonist-induced Rodent Tumors: Modes of Action and Human Relevance Critical Reviews in Toxicology. 2003 | Pubmed ID: 14727734 Minocycline Blocks 6-hydroxydopamine-induced Neurotoxicity and Free Radical Production in Rat Cerebellar Granule Neurons Life Sciences. Feb, 2003 | Pubmed ID: 12551752 Hepatic Effects of 2-butoxyethanol in Rodents Toxicological Sciences : an Official Journal of the Society of Toxicology. Dec, 2002 | Pubmed ID: 12441370 Morphological Transformation and Oxidative Stress Induced by Cyanide in Syrian Hamster Embryo (SHE) Cells Toxicological Sciences : an Official Journal of the Society of Toxicology. Aug, 2002 | Pubmed ID: 12151639 Mechanisms of 2-butoxyethanol Carcinogenicity: Studies on Syrian Hamster Embryo (SHE) Cell Transformation Toxicological Sciences : an Official Journal of the Society of Toxicology. Jul, 2002 | Pubmed ID: 12075109 Mechanisms for the Induction of Oxidative Stress in Syrian Hamster Embryo Cells by Acrylonitrile Toxicological Sciences : an Official Journal of the Society of Toxicology. Jun, 2002 | Pubmed ID: 12011484 Comparative Effects of Phthalate Monoesters on Gap Junctional Intercellular Communication and Peroxisome Proliferation in Rodent and Primate Hepatocytes Journal of Toxicology and Environmental Health. Part A. Apr, 2002 | Pubmed ID: 11995694 Acrylamide-induced Cellular Transformation Toxicological Sciences : an Official Journal of the Society of Toxicology. Feb, 2002 | Pubmed ID: 11812921 Effects of 2-butoxyethanol on Hepatic Oxidative Damage Toxicology Letters. Jan, 2002 | Pubmed ID: 11738267 Análise Temporal Espacial do Fluxo de Campo na Microvasculatura Sherry G. Clendenon1,2, Xiao Fu1,3, Robert A. Von Hoene1, Jeffrey L. Clendenon4, James P. Sluka1,2, Seth Winfree5, Henry Mang5, Michelle Martinez5, Adele Filson5, James E. Klaunig6, James A. Glazier1,2, Kenneth W. Dunn5 1Biocomplexity Institute, Indiana University, 2Department of Intelligent Systems Engineering, Indiana University, 3Department of Physics, Indiana University, 4Scientific Designs, 5Department of Medicine, Indiana University, 6School of Public Health, Indiana University JoVE 60493 Bioengineering
Análise Temporal Espacial do Fluxo de Campo na Microvasculatura Sherry G. Clendenon1,2, Xiao Fu1,3, Robert A. Von Hoene1, Jeffrey L. Clendenon4, James P. Sluka1,2, Seth Winfree5, Henry Mang5, Michelle Martinez5, Adele Filson5, James E. Klaunig6, James A. Glazier1,2, Kenneth W. Dunn5 1Biocomplexity Institute, Indiana University, 2Department of Intelligent Systems Engineering, Indiana University, 3Department of Physics, Indiana University, 4Scientific Designs, 5Department of Medicine, Indiana University, 6School of Public Health, Indiana University JoVE 60493 Bioengineering
