James West Pulmonary and Critical Care Medicine Vanderbilt University Medical Center Biography Publications Institution JoVE Articles James West has not added a biography. If you are James West and would like to personalize this page please email our Author Liaison for assistance. Publications A Multifaceted Investigation into Molecular Associations of Chronic Thromboembolic Pulmonary Hypertension Pathogenesis JRSM Cardiovascular Disease. Jan-Dec, 2020 | Pubmed ID: 32110389 Natriuretic Peptide Receptor C Contributes to Disproportionate Right Ventricular Hypertrophy in a Rodent Model of Obesity-induced Heart Failure with Preserved Ejection Fraction with Pulmonary Hypertension Pulmonary Circulation. Oct-Dec, 2019 | Pubmed ID: 31903184 Baicalin Prevents Pulmonary Arterial Remodeling in Vivo Via the AKT/ERK/NF-κB Signaling Pathways Pulmonary Circulation. Oct-Dec, 2019 | Pubmed ID: 31723406 Low-grade Albuminuria in Pulmonary Arterial Hypertension Pulmonary Circulation. Apr-Jun, 2019 | Pubmed ID: 30632900 Adverse Physiologic Effects of Western Diet on Right Ventricular Structure and Function: Role of Lipid Accumulation and Metabolic Therapy Pulmonary Circulation. Jan-Mar, 2019 | Pubmed ID: 30451070 Clinical and Genetic Associations with Prostacyclin Response in Pulmonary Arterial Hypertension Pulmonary Circulation. Oct-Dec, 2018 | Pubmed ID: 30142026 Ubiquitin Chains: a New Way of Screening for Regulatory Differences in Pulmonary Hypertension Pulmonary Circulation. Jul-Sep, 2018 | Pubmed ID: 30124137 JNK2 Regulates Vascular Remodeling in Pulmonary Hypertension Pulmonary Circulation. Jul-Sep, 2018 | Pubmed ID: 29718758 Genotype-phenotype Effects of Mutations on Disease Severity in Mouse Models of Pulmonary Hypertension Pulmonary Circulation. Dec, 2016 | Pubmed ID: 28090303 Antagonism of the Thromboxane-prostanoid Receptor is Cardioprotective Against Right Ventricular Pressure Overload Pulmonary Circulation. Jun, 2016 | Pubmed ID: 27252848 Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension PloS One. 2016 | Pubmed ID: 26863209 Peripheral Blood Signature of Vasodilator-responsive Pulmonary Arterial Hypertension Circulation. Jan, 2015 | Pubmed ID: 25361553 Role of DNA Methylation and Epigenetic Silencing of HAND2 in Endometrial Cancer Development PLoS Medicine. Nov, 2013 | Pubmed ID: 24265601 Rankings Versus Reality in Pancreatic Cancer Surgery: a Real-world Comparison HPB : the Official Journal of the International Hepato Pancreato Biliary Association. Nov, 2013 | Pubmed ID: 24245953 The Performance Enhancement of a Micro-machined Microphone Based on Field-effect-transistor and Electrets The Journal of the Acoustical Society of America. Nov, 2013 | Pubmed ID: 24181478 A Metabolomics Investigation of Non-genotoxic Carcinogenicity in the Rat Journal of Proteome Research. Nov, 2013 | Pubmed ID: 24161236 Pronounced Toxicity Differences Between Homobifunctional Protein Cross-Linkers and Analogous Monofunctional Electrophiles Chemical Research in Toxicology. Nov, 2013 | Pubmed ID: 24138115 Tumor-specific Activation of an EGFR-targeting Probody Enhances Therapeutic Index Science Translational Medicine. Oct, 2013 | Pubmed ID: 24132639 Hypoxic Regulation of Hand1 Controls the Fetal-neonatal Switch in Cardiac Metabolism PLoS Biology. Sep, 2013 | Pubmed ID: 24086110 Author's Reply Pulmonary Circulation. Apr, 2013 | Pubmed ID: 24015350 Gender, Sex Hormones and Pulmonary Hypertension Pulmonary Circulation. 4, 2013 | Pubmed ID: 24015330 The Material Footprint of Nations Proceedings of the National Academy of Sciences of the United States of America. Sep, 2013 | Pubmed ID: 24003158 Distinctive Topology of Age-associated Epigenetic Drift in the Human Interactome Proceedings of the National Academy of Sciences of the United States of America. Aug, 2013 | Pubmed ID: 23940324 Age-associated Epigenetic Drift: Implications, and a Case of Epigenetic Thrift? Human Molecular Genetics. Oct, 2013 | Pubmed ID: 23918660 Corruption of the Intra-gene DNA Methylation Architecture is a Hallmark of Cancer PloS One. 2013 | Pubmed ID: 23874574 Hyperoxia Synergizes with Mutant Bone Morphogenic Protein Receptor 2 to Cause Metabolic Stress, Oxidant Injury, and Pulmonary Hypertension American Journal of Respiratory Cell and Molecular Biology. Nov, 2013 | Pubmed ID: 23742019 Endocrine Disrupting Chemicals in Fish Bile: a Rapid Method of Analysis Using English Sole (Parophrys Vetulus) from Puget Sound, WA, USA Chemosphere. Sep, 2013 | Pubmed ID: 23683869 Dysfunctional Resident Lung Mesenchymal Stem Cells Contribute to Pulmonary Microvascular Remodeling Pulmonary Circulation. Jan, 2013 | Pubmed ID: 23662173 Histone Deacetylase Inhibitor Enhances Recovery After AKI Journal of the American Society of Nephrology : JASN. May, 2013 | Pubmed ID: 23620402 An Integrative Network Algorithm Identifies Age-associated Differential Methylation Interactome Hotspots Targeting Stem-cell Differentiation Pathways Scientific Reports. 2013 | Pubmed ID: 23568264 Evaluation of Novel Disposable, Light-weight Radiation Protection Devices in an Interventional Radiology Setting: a Randomized Controlled Trial AJR. American Journal of Roentgenology. Apr, 2013 | Pubmed ID: 23521470 Identification and Functional Validation of HPV-mediated Hypermethylation in Head and Neck Squamous Cell Carcinoma Genome Medicine. Feb, 2013 | Pubmed ID: 23419152 Bifunctional Electrophiles Cross-link Thioredoxins with Redox Relay Partners in Cells Chemical Research in Toxicology. Mar, 2013 | Pubmed ID: 23414292 Modification of Hemodynamic and Immune Responses to Exposure with a Weak Antigen by the Expression of a Hypomorphic BMPR2 Gene PloS One. 2013 | Pubmed ID: 23383100 A Process-based Review of Mouse Models of Pulmonary Hypertension Pulmonary Circulation. Oct, 2012 | Pubmed ID: 23372926 A Multiresolution Analysis for Detection of Abnormal Lung Sounds Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2012 | Pubmed ID: 23366591 A Practical Guide to Metabolomic Profiling As a Discovery Tool for Human Heart Disease Journal of Molecular and Cellular Cardiology. Dec, 2012 | Pubmed ID: 23231771 Differential Network Entropy Reveals Cancer System Hallmarks Scientific Reports. 2012 | Pubmed ID: 23150773 Testosterone Negatively Regulates Right Ventricular Load Stress Responses in Mice Pulmonary Circulation. Jul, 2012 | Pubmed ID: 23130103 A Potential Role for Insulin Resistance in Experimental Pulmonary Hypertension The European Respiratory Journal : Official Journal of the European Society for Clinical Respiratory Physiology. Aug, 2012 | Pubmed ID: 22936709 Longitudinal Analysis Casts Doubt on the Presence of Genetic Anticipation in Heritable Pulmonary Arterial Hypertension American Journal of Respiratory and Critical Care Medicine. Nov, 2012 | Pubmed ID: 22923661 Role of BMPR2 Alternative Splicing in Heritable Pulmonary Arterial Hypertension Penetrance Circulation. Oct, 2012 | Pubmed ID: 22923426 Current Clinical Practice in Postoperative Endovascular Aneurysm Repair Imaging Surveillance Journal of Vascular and Interventional Radiology : JVIR. Sep, 2012 | Pubmed ID: 22854317 Metabolomic Analysis of Bone Morphogenetic Protein Receptor Type 2 Mutations in Human Pulmonary Endothelium Reveals Widespread Metabolic Reprogramming Pulmonary Circulation. Apr-Jun, 2012 | Pubmed ID: 22837861 The Yeast Hsp70 Ssa1 is a Sensor for Activation of the Heat Shock Response by Thiol-reactive Compounds Molecular Biology of the Cell. Sep, 2012 | Pubmed ID: 22809627 Small Molecule Activators of the Heat Shock Response: Chemical Properties, Molecular Targets, and Therapeutic Promise Chemical Research in Toxicology. Oct, 2012 | Pubmed ID: 22799889 Approximate Entropy of Network Parameters Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. Apr, 2012 | Pubmed ID: 22680542 CD40 Amplifies Fas-mediated Apoptosis: a Mechanism Contributing to Emphysema American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2012 | Pubmed ID: 22610351 Whole Exome Sequencing to Identify a Novel Gene (caveolin-1) Associated with Human Pulmonary Arterial Hypertension Circulation. Cardiovascular Genetics. Jun, 2012 | Pubmed ID: 22474227 The A2B Adenosine Receptor Modulates Pulmonary Hypertension Associated with Interstitial Lung Disease FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2012 | Pubmed ID: 22415303 BMPR2 Expression is Suppressed by Signaling Through the Estrogen Receptor Biology of Sex Differences. 2012 | Pubmed ID: 22348410 Connectivity Map Analysis of Nonsense-mediated Decay-positive BMPR2-related Hereditary Pulmonary Arterial Hypertension Provides Insights into Disease Penetrance American Journal of Respiratory Cell and Molecular Biology. Jul, 2012 | Pubmed ID: 22312021 Computerised Lung Sound Analysis to Improve the Specificity of Paediatric Pneumonia Diagnosis in Resource-poor Settings: Protocol and Methods for an Observational Study BMJ Open. 2012 | Pubmed ID: 22307098 Unexpectedly High Mortality in Pacific Herring Embryos Exposed to the 2007 Cosco Busan Oil Spill in San Francisco Bay Proceedings of the National Academy of Sciences of the United States of America. Jan, 2012 | Pubmed ID: 22203989 Cytoskeletal Defects in Bmpr2-associated Pulmonary Arterial Hypertension American Journal of Physiology. Lung Cellular and Molecular Physiology. Mar, 2012 | Pubmed ID: 22180660 Disruption of Bone Morphogenetic Protein Receptor 2 (BMPR2) in Mammary Tumors Promotes Metastases Through Cell Autonomous and Paracrine Mediators Proceedings of the National Academy of Sciences of the United States of America. Feb, 2012 | Pubmed ID: 21576484 Idiopathic and Heritable PAH Perturb Common Molecular Pathways, Correlated with Increased MSX1 Expression Pulmonary Circulation. Jul-Sep, 2011 | Pubmed ID: 22140629 Oxidative Injury is a Common Consequence of BMPR2 Mutations Pulmonary Circulation. 2011 | Pubmed ID: 21904662 Rho-kinase Inhibition Alleviates Pulmonary Hypertension in Transgenic Mice Expressing a Dominant-negative Type II Bone Morphogenetic Protein Receptor Gene American Journal of Physiology. Lung Cellular and Molecular Physiology. Nov, 2011 | Pubmed ID: 21856816 Are Obliterative Pulmonary Vascular Lesions Reversible? American Journal of Respiratory and Critical Care Medicine. Aug, 2011 | Pubmed ID: 21844514 Enhanced Toxicity of the Protein Cross-linkers Divinyl Sulfone and Diethyl Acetylenedicarboxylate in Comparison to Related Monofunctional Electrophiles Chemical Research in Toxicology. Sep, 2011 | Pubmed ID: 21812477 Permanent Polarity and Piezoelectricity of Electrospun α-helical Poly(α-amino Acid) Fibers Advanced Materials (Deerfield Beach, Fla.). Sep, 2011 | Pubmed ID: 21796687 Physiologic and Molecular Consequences of Endothelial Bmpr2 Mutation Respiratory Research. 2011 | Pubmed ID: 21696628 ACE2 Improves Right Ventricular Function in a Pressure Overload Model PloS One. 2011 | Pubmed ID: 21695173 Inhalation of Stachybotrys Chartarum Evokes Pulmonary Arterial Remodeling in Mice, Attenuated by Rho-kinase Inhibitor Mycopathologia. Jul, 2011 | Pubmed ID: 21505873 Unrecognized Glucose Intolerance is Common in Pulmonary Arterial Hypertension The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Aug, 2011 | Pubmed ID: 21493097 Vstm3 is a Member of the CD28 Family and an Important Modulator of T-cell Function European Journal of Immunology. Apr, 2011 | Pubmed ID: 21416464 The Pathology of Bleomycin-induced Fibrosis is Associated with Loss of Resident Lung Mesenchymal Stem Cells That Regulate Effector T-cell Proliferation Stem Cells (Dayton, Ohio). Apr, 2011 | Pubmed ID: 21312316 Structure-activity Comparison of the Cytotoxic Properties of Diethyl Maleate and Related Molecules: Identification of Diethyl Acetylenedicarboxylate As a Thiol Cross-linking Agent Chemical Research in Toxicology. Jan, 2011 | Pubmed ID: 21105742 Cross Talk Between Smad, MAPK, and Actin in the Etiology of Pulmonary Arterial Hypertension Advances in Experimental Medicine and Biology. 2010 | Pubmed ID: 20204736 Engineering of Stable Bispecific Antibodies Targeting IL-17A and IL-23 Protein Engineering, Design & Selection : PEDS. Mar, 2010 | Pubmed ID: 20022918 Effects of Neonatal Alcohol Exposure on Vasoactive Intestinal Polypeptide Neurons in the Rat Suprachiasmatic Nucleus Alcohol (Fayetteville, N.Y.). Aug, 2009 | Pubmed ID: 19671465 Shock-synthesized Hexagonal Diamonds in Younger Dryas Boundary Sediments Proceedings of the National Academy of Sciences of the United States of America. Aug, 2009 | Pubmed ID: 19620728 Copy-number Variation in BMPR2 is Not Associated with the Pathogenesis of Pulmonary Arterial Hypertension BMC Medical Genetics. 2009 | Pubmed ID: 19531247 Protein Microarray Analysis of Nasal Polyps from Aspirin-sensitive and Aspirin-tolerant Patients with Chronic Rhinosinusitis American Journal of Rhinology & Allergy. May-Jun, 2009 | Pubmed ID: 19490800 Gene Expression in Lungs of Mice Lacking the 5-hydroxytryptamine Transporter Gene BMC Pulmonary Medicine. 2009 | Pubmed ID: 19426553 A Noncoding RNA Gene on Chromosome 10p15.3 May Function Upstream of HTERT BMC Molecular Biology. 2009 | Pubmed ID: 19187532 Gene Expression in BMPR2 Mutation Carriers with and Without Evidence of Pulmonary Arterial Hypertension Suggests Pathways Relevant to Disease Penetrance BMC Medical Genomics. 2008 | Pubmed ID: 18823550 Mice Expressing BMPR2R899X Transgene in Smooth Muscle Develop Pulmonary Vascular Lesions American Journal of Physiology. Lung Cellular and Molecular Physiology. Nov, 2008 | Pubmed ID: 18723761 Circulating RNA Transcripts Identify Therapeutic Response in Cystic Fibrosis Lung Disease American Journal of Respiratory and Critical Care Medicine. Nov, 2008 | Pubmed ID: 18723435 Murine Pulmonary Response to Chronic Hypoxia is Strain Specific Experimental Lung Research. Aug, 2008 | Pubmed ID: 18600498 Xenoestrogen Exposure and Effects in English Sole (Parophrys Vetulus) from Puget Sound, WA Aquatic Toxicology (Amsterdam, Netherlands). Jun, 2008 | Pubmed ID: 18423645 Alcohol Exposure on Postnatal Day 5 Induces Purkinje Cell Loss and Evidence of Purkinje Cell Degradation in Lobule I of Rat Cerebellum Alcohol (Fayetteville, N.Y.). Jun, 2008 | Pubmed ID: 18400452 Spatial Extent, Magnitude, and Patterns of Persistent Organochlorine Pollutants in Pacific Herring (Clupea Pallasi) Populations in the Puget Sound (USA) and Strait of Georgia (Canada) The Science of the Total Environment. May, 2008 | Pubmed ID: 18314160 Abrogation of Anti-inflammatory Transcription Factor LKLF in Neutrophil-dominated Airways American Journal of Respiratory Cell and Molecular Biology. Jun, 2008 | Pubmed ID: 18218994 Neonatal Alcohol Exposure Differentially Alters Clock Gene Oscillations Within the Suprachiasmatic Nucleus, Cerebellum, and Liver of Adult Rats Alcoholism, Clinical and Experimental Research. Mar, 2008 | Pubmed ID: 18215209 Activation of Heat Shock and Antioxidant Responses by the Natural Product Celastrol: Transcriptional Signatures of a Thiol-targeted Molecule Molecular Biology of the Cell. Mar, 2008 | Pubmed ID: 18199679 Solution-processed Organic Field-effect Transistors and Unipolar Inverters Using Self-assembled Interface Dipoles on Gate Dielectrics Langmuir : the ACS Journal of Surfaces and Colloids. Dec, 2007 | Pubmed ID: 18020470 Identification of the IL-17 Receptor Related Molecule IL-17RC As the Receptor for IL-17F Journal of Immunology (Baltimore, Md. : 1950). Oct, 2007 | Pubmed ID: 17911633 The Relationship Between Distance to Hospital and Patient Mortality in Emergencies: an Observational Study Emergency Medicine Journal : EMJ. Sep, 2007 | Pubmed ID: 17711952 Temporal Vulnerability of Fetal Cerebellar Purkinje Cells to Chronic Binge Alcohol Exposure: Ovine Model Alcoholism, Clinical and Experimental Research. Oct, 2007 | Pubmed ID: 17681031 Serotonin Transporter Protein in Pulmonary Hypertensive Rats Treated with Atorvastatin American Journal of Physiology. Lung Cellular and Molecular Physiology. Sep, 2007 | Pubmed ID: 17575010 Quieting Weinberg 5C: a Case Study in Hospital Noise Control The Journal of the Acoustical Society of America. Jun, 2007 | Pubmed ID: 17552702 Noise in the Operating Rooms of Johns Hopkins Hospital The Journal of the Acoustical Society of America. May, 2007 | Pubmed ID: 17550167 Chronic Ethanol Increases Fetal Cerebral Blood Flow Specific to the Ethanol-sensitive Cerebellum Under Normoxaemic, Hypercapnic and Acidaemic Conditions: Ovine Model Experimental Physiology. Sep, 2007 | Pubmed ID: 17526556 Ethical Issues and New Nurses: Preventing Ethical Distress in the Work Environment The Kansas Nurse. Apr, 2007 | Pubmed ID: 17523368 Noise in the Adult Emergency Department of Johns Hopkins Hospital The Journal of the Acoustical Society of America. Apr, 2007 | Pubmed ID: 17471716 Molecular Effects of Loss of BMPR2 Signaling in Smooth Muscle in a Transgenic Mouse Model of PAH American Journal of Physiology. Lung Cellular and Molecular Physiology. Jun, 2007 | Pubmed ID: 17369292 Interaction of Interleukin-6 and the BMP Pathway in Pulmonary Smooth Muscle American Journal of Physiology. Lung Cellular and Molecular Physiology. Jun, 2007 | Pubmed ID: 17322283 Uptake and Elimination of Ethanol by Young Zebrafish Embryos Neurotoxicology and Teratology. Sep-Oct, 2006 | Pubmed ID: 16916596 Binge Alcohol Exposure During All Three Trimesters Alters Bone Strength and Growth in Fetal Sheep Alcohol (Fayetteville, N.Y.). Apr, 2006 | Pubmed ID: 16905445 Nicotine Decreases Blood Alcohol Concentrations in Adult Rats: a Phenomenon Potentially Related to Gastric Function Alcoholism, Clinical and Experimental Research. Aug, 2006 | Pubmed ID: 16899044 Endogenous Reactive Intermediates As Modulators of Cell Signaling and Cell Death Chemical Research in Toxicology. Feb, 2006 | Pubmed ID: 16485894 Embryonic Growth-associated Protein is One Subunit of a Novel N-terminal Acetyltransferase Complex Essential for Embryonic Vascular Development Circulation Research. Mar, 2006 | Pubmed ID: 16484612 Perspectives on the Massachusetts Community Health Information Profile (MassCHIP): Developing an Online Data Query System to Target a Variety of User Needs and Capabilities Journal of Public Health Management and Practice : JPHMP. Mar-Apr, 2006 | Pubmed ID: 16479229 BMP Signaling Controls PASMC KV Channel Expression in Vitro and in Vivo American Journal of Physiology. Lung Cellular and Molecular Physiology. May, 2006 | Pubmed ID: 16339782 Long-term Effects of Neonatal Alcohol Exposure on Photic Reentrainment and Phase-shifting Responses of the Activity Rhythm in Adult Rats Alcohol (Fayetteville, N.Y.). Oct, 2005 | Pubmed ID: 16584971 Noise Levels in Johns Hopkins Hospital The Journal of the Acoustical Society of America. Dec, 2005 | Pubmed ID: 16419808 A Bone-derived Mixture of TGF Beta-superfamily Members Forms a More Mature Vascular Network Than BFGF or TGF-beta 2 in Vivo Angiogenesis. 2005 | Pubmed ID: 16400522 Interleukin-6 Causes Mild Pulmonary Hypertension and Augments Hypoxia-induced Pulmonary Hypertension in Mice Chest. Dec, 2005 | Pubmed ID: 16373831 Suppression of Type II Bone Morphogenic Protein Receptor in Vascular Smooth Muscle Induces Pulmonary Arterial Hypertension in Transgenic Mice Chest. Dec, 2005 | Pubmed ID: 16373822 Alterations in Gene Expression Induced by the Lipid Peroxidation Product, 4-hydroxy-2-nonenal Chemical Research in Toxicology. Nov, 2005 | Pubmed ID: 16300372 Neonatal Alcohol Exposure Permanently Disrupts the Circadian Properties and Photic Entrainment of the Activity Rhythm in Adult Rats Alcoholism, Clinical and Experimental Research. Oct, 2005 | Pubmed ID: 16269914 Complications from Olanzapine in a Mentally Healthy Patient The American Journal of Psychiatry. Sep, 2005 | Pubmed ID: 16135645 General Discussion at the Fetal Alcohol Syndrome Symposium Experimental Biology and Medicine (Maywood, N.J.). Jun, 2005 | Pubmed ID: 15956770 Fetal Alcohol Syndrome: an Assessment of the Field Experimental Biology and Medicine (Maywood, N.J.). Jun, 2005 | Pubmed ID: 15956764 Low-voltage-activated (T-type) Calcium Channels Control Proliferation of Human Pulmonary Artery Myocytes Circulation Research. Apr, 2005 | Pubmed ID: 15774856 Modulation of DNA Fragmentation Factor 40 Nuclease Activity by Poly(ADP-ribose) Polymerase-1 The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15703174 Surface Modes in Air-core Photonic Band-gap Fibers Optics Express. Apr, 2004 | Pubmed ID: 19474974 Tumor Necrosis Factor-related Apoptosis-inducing Ligand Can Induce Apoptosis in Subsets of Premalignant Cells The American Journal of Pathology. Nov, 2004 | Pubmed ID: 15509531 Long-term Alcohol Exposure Prior to Conception Results in Lower Fetal Body Weights Birth Defects Research. Part B, Developmental and Reproductive Toxicology. Jun, 2004 | Pubmed ID: 15282734 Developmental Alcohol Exposure Alters Light-induced Phase Shifts of the Circadian Activity Rhythm in Rats Alcoholism, Clinical and Experimental Research. Jul, 2004 | Pubmed ID: 15252288 Adenoviral Gene Transfer to the Neonatal Rat Pulmonary Circulation The Journal of Gene Medicine. Jul, 2004 | Pubmed ID: 15241780 Developmental Alcohol Exposure Disrupts Circadian Regulation of BDNF in the Rat Suprachiasmatic Nucleus Neurotoxicology and Teratology. May-Jun, 2004 | Pubmed ID: 15113597 Induction of Apoptosis in Colorectal Carcinoma Cells Treated with 4-hydroxy-2-nonenal and Structurally Related Aldehydic Products of Lipid Peroxidation Chemical Research in Toxicology. Apr, 2004 | Pubmed ID: 15089087 Pulmonary Hypertension in Transgenic Mice Expressing a Dominant-negative BMPRII Gene in Smooth Muscle Circulation Research. Apr, 2004 | Pubmed ID: 15031260 A Beam Tracing Method for Interactive Architectural Acoustics The Journal of the Acoustical Society of America. Feb, 2004 | Pubmed ID: 15000186 Alcohol and the Developing Brain: Neuroanatomical Studies Alcohol Research & Health : the Journal of the National Institute on Alcohol Abuse and Alcoholism. 2003 | Pubmed ID: 15303628 Low-loss Hollow-core Silica/air Photonic Bandgap Fibre Nature. Aug, 2003 | Pubmed ID: 12904788 Alcohol and Nutritional Control Treatments During Neurogenesis in Rat Brain Reduce Total Neuron Number in Locus Coeruleus, but Not in Cerebellum or Inferior Olive Alcohol (Fayetteville, N.Y.). May, 2003 | Pubmed ID: 12878276 Blood Ethanol Concentration Profiles: a Comparison Between Rats and Mice Alcohol (Fayetteville, N.Y.). Apr, 2003 | Pubmed ID: 12798972 Fetal Alcohol Exposure and Temporal Vulnerability: Effects of Binge-like Alcohol Exposure on the Developing Rat Hippocampus Neurotoxicology and Teratology. Jul-Aug, 2003 | Pubmed ID: 12798962 Endogenous Generation of Reactive Oxidants and Electrophiles and Their Reactions with DNA and Protein The Journal of Clinical Investigation. Mar, 2003 | Pubmed ID: 12618510 Pseudomonas Aeruginosa-human Airway Epithelial Cell Interaction: Effects of Iron on Inflammation and Apoptosis Chest. Mar, 2002 | Pubmed ID: 11893679 Fetal and Maternal Thyroid Hormone Responses to Ethanol Exposure During the Third Trimester Equivalent of Gestation in Sheep Alcoholism, Clinical and Experimental Research. Jan, 2002 | Pubmed ID: 11821654 Expression of a Human Caveolin-1 Mutation in Mice Drives Inflammatory and Metabolic Defect-Associated Pulmonary Arterial Hypertension Frontiers in Medicine. | Pubmed ID: 33015095 Resident Mesenchymal Vascular Progenitors Modulate Adaptive Angiogenesis and Pulmonary Remodeling Via Regulation of Canonical Wnt Signaling FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. | Pubmed ID: 32533805 Dysfunction Impairs Insulin Signaling and Glucose Homeostasis in Cardiomyocytes American Journal of Physiology. Lung Cellular and Molecular Physiology. | Pubmed ID: 31850803 Antagonism of the Thromboxane-Prostanoid Receptor As a Potential Therapy for Cardiomyopathy of Muscular Dystrophy Journal of the American Heart Association. | Pubmed ID: 31662020 Machine Learning-based Microarray Analyses Indicate Low-expression Genes Might Collectively Influence PAH Disease PLoS Computational Biology. | Pubmed ID: 31404060 Adverse Effects of BMPR2 Suppression in Macrophages in Animal Models of Pulmonary Hypertension Pulmonary Circulation. | Pubmed ID: 31124398 Human PAH is Characterized by a Pattern of Lipid-related Insulin Resistance JCI Insight. | Pubmed ID: 30626738 Bone Marrow-Derived Proangiogenic Cells Mediate Pulmonary Arteriole Stiffening Via Serotonin 2B Receptor Dependent Mechanism Circulation Research. | Pubmed ID: 30566041 Pulmonary Vascular Platform Models the Effects of Flow and Pressure on Endothelial Dysfunction in Associated Pulmonary Arterial Hypertension International Journal of Molecular Sciences. | Pubmed ID: 30158434 A Potential Therapeutic Role for Angiotensin-converting Enzyme 2 in Human Pulmonary Arterial Hypertension The European Respiratory Journal. | Pubmed ID: 29903860 RhACE2 Therapy Modifies Bleomycin-Induced Pulmonary Hypertension Via Rescue of Vascular Remodeling Frontiers in Physiology. | Pubmed ID: 29731719 The Selective Angiotensin II Type 2 Receptor Agonist, Compound 21, Attenuates the Progression of Lung Fibrosis and Pulmonary Hypertension in an Experimental Model of Bleomycin-Induced Lung Injury Frontiers in Physiology. | Pubmed ID: 29636695 Precision Modeling of Pulmonary Hypertension Pathology with Induced Pluripotent Stem Cell-derived Cells American Journal of Respiratory and Critical Care Medicine. | Pubmed ID: 29596760 Monitoring Uterine Contractility in Mice Using a Transcervical Intrauterine Pressure Catheter Reproduction (Cambridge, England). | Pubmed ID: 29500186 Upregulation of SERT and ADORA1 in Broilers with Acute Right Ventricular Failure Research in Veterinary Science. | Pubmed ID: 29174607 Vildagliptin Ameliorates Pulmonary Fibrosis in Lipopolysaccharide-induced Lung Injury by Inhibiting Endothelial-to-mesenchymal Transition Respiratory Research. | Pubmed ID: 29037205 Isolation and Characterization of Endothelial-to-mesenchymal Transition Cells in Pulmonary Arterial Hypertension American Journal of Physiology. Lung Cellular and Molecular Physiology. | Pubmed ID: 28935639 Oestrogen Inhibition Reverses Pulmonary Arterial Hypertension and Associated Metabolic Defects The European Respiratory Journal. | Pubmed ID: 28775043 The Relationship of Bone Mineral Density in Men with Chronic Obstructive Pulmonary Disease Classified According to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) Combined Chronic Obstructive Pulmonary Disease (COPD) Assessment System Internal Medicine (Tokyo, Japan). | Pubmed ID: 28717072 Dysfunctional BMPR2 Signaling Drives an Abnormal Endothelial Requirement for Glutamine in Pulmonary Arterial Hypertension Pulmonary Circulation. | Pubmed ID: 28680578 Disruption of Lineage Specification in Adult Pulmonary Mesenchymal Progenitor Cells Promotes Microvascular Dysfunction The Journal of Clinical Investigation. | Pubmed ID: 28463231 Genome Editing in Large Animals Journal of Equine Veterinary Science. | Pubmed ID: 27766006 Novel Signaling Pathways in Pulmonary Arterial Hypertension (2015 Grover Conference Series) Pulmonary Circulation. | Pubmed ID: 27683605 Scavengers of Reactive γ-ketoaldehydes Extend Caenorhabditis Elegans Lifespan and Healthspan Through Protein-level Interactions with SIR-2.1 and ETS-7 Aging. | Pubmed ID: 27514077 Reply: Expanded Role for Bone Marrow-derived Hematopoietic Stem and Progenitor Cells in Pulmonary Arterial Hypertension American Journal of Respiratory and Critical Care Medicine. | Pubmed ID: 27479065 Translational Advances in the Field of Pulmonary Hypertension Molecular Medicine of Pulmonary Arterial Hypertension. From Population Genetics to Precision Medicine and Gene Editing American Journal of Respiratory and Critical Care Medicine. | Pubmed ID: 27398627 Endothelial-to-mesenchymal Transition in Lipopolysaccharide-induced Acute Lung Injury Drives a Progenitor Cell-like Phenotype American Journal of Physiology. Lung Cellular and Molecular Physiology. | Pubmed ID: 27106288 Mechanisms of Lipid Accumulation in the Bone Morphogenetic Protein Receptor Type 2 Mutant Right Ventricle American Journal of Respiratory and Critical Care Medicine. | Pubmed ID: 27077479 Fatty Acid Metabolic Defects and Right Ventricular Lipotoxicity in Human Pulmonary Arterial Hypertension Circulation. | Pubmed ID: 27006481 Bone Marrow-derived Cells Contribute to the Pathogenesis of Pulmonary Arterial Hypertension American Journal of Respiratory and Critical Care Medicine. | Pubmed ID: 26651104 Enhanced Caveolin-1 Expression in Smooth Muscle Cells: Possible Prelude to Neointima Formation World Journal of Cardiology. | Pubmed ID: 26516422 Estrogen Metabolite 16α-Hydroxyestrone Exacerbates Bone Morphogenetic Protein Receptor Type II-Associated Pulmonary Arterial Hypertension Through MicroRNA-29-Mediated Modulation of Cellular Metabolism Circulation. | Pubmed ID: 26487756 Influence of Pulmonary Emphysema on COPD Assessment Test-oriented Categorization in GOLD Document International Journal of Chronic Obstructive Pulmonary Disease. | Pubmed ID: 26150711 Systems-level Regulation of MicroRNA Networks by MiR-130/301 Promotes Pulmonary Hypertension The Journal of Clinical Investigation. | Pubmed ID: 24960162 Rescuing the BMPR2 Signaling Axis in Pulmonary Arterial Hypertension Drug Discovery Today. | Pubmed ID: 24794464 Interaction Between Bone Morphogenetic Protein Receptor Type 2 and Estrogenic Compounds in Pulmonary Arterial Hypertension Pulmonary Circulation. | Pubmed ID: 24618541 Echocardiographic Assessment of the Right Heart in Mice Journal of Visualized Experiments : JoVE. | Pubmed ID: 24326586 Evidence for Right Ventricular Lipotoxicity in Heritable Pulmonary Arterial Hypertension American Journal of Respiratory and Critical Care Medicine. | Pubmed ID: 24274756 Experimental and Transgenic Models of Pulmonary Hypertension Comprehensive Physiology. | Pubmed ID: 23737202 Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice Journal of Visualized Experiments : JoVE. | Pubmed ID: 23354416 Echocardiographic Assessment of the Right Heart in Mice Evan Brittain1, Niki L. Penner2, James West2, Anna Hemnes2 1Division of Cardiovascular Medicine, Vanderbilt University Medical Center, 2Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center JoVE 50912 Medicine Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice Wen-Chi Chen*1, Sung-Hyun Park*1, Carol Hoffman1, Cecil Philip1, Linda Robinson2, James West2, Gabriele Grunig1,3 1Department of Environmental Medicine, New York University School of Medicine, Tuxedo, 2Division of Allergy, Pulmonary, & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, 3Division of Pulmonary Medicine, New York University School of Medicine JoVE 50023 Immunology and Infection
Echocardiographic Assessment of the Right Heart in Mice Evan Brittain1, Niki L. Penner2, James West2, Anna Hemnes2 1Division of Cardiovascular Medicine, Vanderbilt University Medical Center, 2Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center JoVE 50912 Medicine
Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice Wen-Chi Chen*1, Sung-Hyun Park*1, Carol Hoffman1, Cecil Philip1, Linda Robinson2, James West2, Gabriele Grunig1,3 1Department of Environmental Medicine, New York University School of Medicine, Tuxedo, 2Division of Allergy, Pulmonary, & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, 3Division of Pulmonary Medicine, New York University School of Medicine JoVE 50023 Immunology and Infection
