Jan-Åke Gustafsson Department of Biology and Biochemistry, Center for Nuclear Receptors and Cell Signaling University of Houston Biography Publications Institution JoVE Articles Jan-Åke Gustafsson has not added a biography. If you are Jan-Åke Gustafsson and would like to personalize this page please email our Author Liaison for assistance. Publications MRNA As a Novel Treatment Strategy for Hereditary Spastic Paraplegia Type 5 Molecular Therapy. Methods & Clinical Development. Dec, 2019 | Pubmed ID: 31828178 Selective Estrogen Receptor (ER)β Activation Provokes a Redistribution of Fat Mass and Modifies Hepatic Triglyceride Composition in Obese Male Mice Molecular and Cellular Endocrinology. Dec, 2019 | Pubmed ID: 31811898 Lipidomic Analysis of Human Primary Hepatocytes Following LXR Activation with GW3965 Identifies AGXT2L1 As a Main Target Associated to Changes in Phosphatidylethanolamine The Journal of Steroid Biochemistry and Molecular Biology. Nov, 2019 | Pubmed ID: 31783151 Immunoregulatory Functions of Nuclear Receptors: Mechanisms and Therapeutic Implications Trends in Endocrinology and Metabolism: TEM. Nov, 2019 | Pubmed ID: 31706690 Absence of Estrogen Receptor Beta Leads to Abnormal Adipogenesis During Early Tendon Healing by an Up-regulation of PPARγ Signalling Journal of Cellular and Molecular Medicine. Nov, 2019 | Pubmed ID: 31475784 Liver X Receptor Alpha Is Important in Maintaining Blood-Brain Barrier Function Frontiers in Immunology. 2019 | Pubmed ID: 31417573 Differential Activity of BPA, BPAF and BPC on Zebrafish Estrogen Receptors in Vitro and in Vivo Toxicology and Applied Pharmacology. Oct, 2019 | Pubmed ID: 31415773 Retinal and Optic Nerve Degeneration in Liver X Receptor β Knockout Mice Proceedings of the National Academy of Sciences of the United States of America. Aug, 2019 | Pubmed ID: 31371497 Bisphenol A Regulates Sodium Ramp Currents in Mouse Dorsal Root Ganglion Neurons and Increases Nociception Scientific Reports. Jul, 2019 | Pubmed ID: 31312012 Oestrogen Receptor β Mediates the Actions of Bisphenol-A on Ion Channel Expression in Mouse Pancreatic Beta Cells Diabetologia. 09, 2019 | Pubmed ID: 31250031 Update on ERbeta The Journal of Steroid Biochemistry and Molecular Biology. 07, 2019 | Pubmed ID: 30995525 VSMC-specific EP4 Deletion Exacerbates Angiotensin II-induced Aortic Dissection by Increasing Vascular Inflammation and Blood Pressure Proceedings of the National Academy of Sciences of the United States of America. Apr, 2019 | Pubmed ID: 30948641 Nuclear Receptors: Recent Drug Discovery for Cancer Therapies Endocrine Reviews. 10, 2019 | Pubmed ID: 30869771 Sex-specific Lipid Molecular Signatures in Obesity-associated Metabolic Dysfunctions Revealed by Lipidomic Characterization in Ob/ob Mouse Biology of Sex Differences. 02, 2019 | Pubmed ID: 30808418 Concentrations of Bile Acid Precursors in Cerebrospinal Fluid of Alzheimer's Disease Patients Free Radical Biology & Medicine. 04, 2019 | Pubmed ID: 30578919 Colitis-induced Colorectal Cancer and Intestinal Epithelial Estrogen Receptor Beta Impact Gut Microbiota Diversity International Journal of Cancer. 06, 2019 | Pubmed ID: 30515752 Role of HSD17B13 in the Liver Physiology and Pathophysiology Molecular and Cellular Endocrinology. 06, 2019 | Pubmed ID: 30365983 ERβ Activation in Obesity Improves Whole Body Metabolism Via Adipose Tissue Function and Enhanced Mitochondria Biogenesis Molecular and Cellular Endocrinology. 01, 2019 | Pubmed ID: 30342056 LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration Through Cis-Repression and Cholesterol Efflux Cell Reports. 12, 2018 | Pubmed ID: 30590048 The Estrogen Receptor Variants β2 and β5 Induce Stem Cell Characteristics and Chemotherapy Resistance in Prostate Cancer Through Activation of Hypoxic Signaling Oncotarget. Nov, 2018 | Pubmed ID: 30555629 Combining Mouse Embryonic Stem Cells and Zebrafish Embryos to Evaluate Developmental Toxicity of Chemical Exposure Reproductive Toxicology (Elmsford, N.Y.). 10, 2018 | Pubmed ID: 30103011 ERβ Alters the Chemosensitivity of Luminal Breast Cancer Cells by Regulating P53 Function Oncotarget. Apr, 2018 | Pubmed ID: 29854295 Estrogen Receptor β Controls Proliferation of Enteric Glia and Differentiation of Neurons in the Myenteric Plexus After Damage Proceedings of the National Academy of Sciences of the United States of America. 05, 2018 | Pubmed ID: 29760072 Farnesoid X Receptor is Essential for the Survival of Renal Medullary Collecting Duct Cells Under Hypertonic Stress Proceedings of the National Academy of Sciences of the United States of America. 05, 2018 | Pubmed ID: 29739889 Human Proislet Peptide Promotes Pancreatic Progenitor Cells to Ameliorate Diabetes Through FOXO1/Menin-Mediated Epigenetic Regulation Diabetes. 07, 2018 | Pubmed ID: 29716892 Pharmacological Activation of Estrogen Receptor Beta Augments Innate Immunity to Suppress Cancer Metastasis Proceedings of the National Academy of Sciences of the United States of America. 04, 2018 | Pubmed ID: 29592953 The ERβ4 Variant Induces Transformation of the Normal Breast Mammary Epithelial Cell Line MCF-10A; the ERβ Variants ERβ2 and ERβ5 Increase Aggressiveness of TNBC by Regulation of Hypoxic Signaling Oncotarget. Feb, 2018 | Pubmed ID: 29552303 Author Correction: Molecular Mechanisms Involved in the Non-monotonic Effect of Bisphenol-a on Ca Entry in Mouse Pancreatic β-cells Scientific Reports. Mar, 2018 | Pubmed ID: 29511196 Liver X Receptor β Regulates the Development of the Dentate Gyrus and Autistic-like Behavior in the Mouse Proceedings of the National Academy of Sciences of the United States of America. 03, 2018 | Pubmed ID: 29507213 Body Weight Homeostat That Regulates Fat Mass Independently of Leptin in Rats and Mice Proceedings of the National Academy of Sciences of the United States of America. Jan, 2018 | Pubmed ID: 29279372 ERβ Sensitizes NSCLC to Chemotherapy by Regulating DNA Damage Response Molecular Cancer Research : MCR. 02, 2018 | Pubmed ID: 29117942 Genomics of Sex Hormone Receptor Signaling in Hepatic Sexual Dimorphism Molecular and Cellular Endocrinology. 08, 2018 | Pubmed ID: 28554805 Role of Estrogen Receptor Beta in Neural Differentiation of Mouse Embryonic Stem Cells Proceedings of the National Academy of Sciences of the United States of America. 11, 2017 | Pubmed ID: 29133394 Estrogen Receptor β2 Induces Proliferation and Invasiveness of Triple Negative Breast Cancer Cells: Association with Regulation of PHD3 and HIF-1α Oncotarget. Sep, 2017 | Pubmed ID: 29100336 Molecular Mechanisms Involved in the Non-monotonic Effect of Bisphenol-a on Ca2+ Entry in Mouse Pancreatic β-cells Scientific Reports. 09, 2017 | Pubmed ID: 28924161 Intratumor Heterogeneity Predicts Metastasis of Triple-negative Breast Cancer Carcinogenesis. 09, 2017 | Pubmed ID: 28911002 Somatic Loss of Estrogen Receptor Beta and P53 Synergize to Induce Breast Tumorigenesis Breast Cancer Research : BCR. Jul, 2017 | Pubmed ID: 28673316 Estrogen Receptor β, a Regulator of Androgen Receptor Signaling in the Mouse Ventral Prostate Proceedings of the National Academy of Sciences of the United States of America. 05, 2017 | Pubmed ID: 28439009 Ablation of Cytochrome P450 Omega-hydroxylase 4A14 Gene Attenuates Hepatic Steatosis and Fibrosis Proceedings of the National Academy of Sciences of the United States of America. 03, 2017 | Pubmed ID: 28270609 Liver X Receptor α Induces 17β-hydroxysteroid Dehydrogenase-13 Expression Through SREBP-1c American Journal of Physiology. Endocrinology and Metabolism. 04, 2017 | Pubmed ID: 28270440 High-Fat Diet Induces Unexpected Fatal Uterine Infections in Mice with AP2-Cre-mediated Deletion of Estrogen Receptor Alpha Scientific Reports. 02, 2017 | Pubmed ID: 28233809 Sex Differences and Effects of Oestrogen in Rat Gastric Mucosal Defence World Journal of Gastroenterology. Jan, 2017 | Pubmed ID: 28210078 Liver X Receptor β Increases Aquaporin 2 Protein Level Via a Posttranscriptional Mechanism in Renal Collecting Ducts American Journal of Physiology. Renal Physiology. 04, 2017 | Pubmed ID: 28052875 Speedy A-Cdk2 Binding Mediates Initial Telomere-nuclear Envelope Attachment During Meiotic Prophase I Independent of Cdk2 Activation Proceedings of the National Academy of Sciences of the United States of America. 01, 2017 | Pubmed ID: 28031483 Estrogen Receptor β As a Pharmaceutical Target Trends in Pharmacological Sciences. 01, 2017 | Pubmed ID: 27979317 Identification of Vascular Disruptor Compounds by Analysis in Zebrafish Embryos and Mouse Embryonic Endothelial Cells Reproductive Toxicology (Elmsford, N.Y.). 06, 2017 | Pubmed ID: 27838387 Defective Cholesterol Metabolism in Amyotrophic Lateral Sclerosis Journal of Lipid Research. 01, 2017 | Pubmed ID: 27811233 On the Regulatory Importance of 27-hydroxycholesterol in Mouse Liver The Journal of Steroid Biochemistry and Molecular Biology. 05, 2017 | Pubmed ID: 26851362 Liver X Receptor β Is Involved in Formalin-Induced Spontaneous Pain Molecular Neurobiology. Mar, 2017 | Pubmed ID: 26846362 An ERβ Agonist Induces Browning of Subcutaneous Abdominal Fat Pad in Obese Female Mice Scientific Reports. 12, 2016 | Pubmed ID: 27922125 Dysregulation of Notch and ERα Signaling in AhR-/- Male Mice Proceedings of the National Academy of Sciences of the United States of America. 10, 2016 | Pubmed ID: 27688768 24-Hydroxycholesterol Participates in Pancreatic Neuroendocrine Tumor Development Proceedings of the National Academy of Sciences of the United States of America. 10, 2016 | Pubmed ID: 27671648 Memo Interacts with C-Src to Control Estrogen Receptor Alpha Sub-cellular Localization Oncotarget. Aug, 2016 | Pubmed ID: 27472465 Prostaglandin E2 Receptor EP3 Regulates Both Adipogenesis and Lipolysis in Mouse White Adipose Tissue Journal of Molecular Cell Biology. 12, 2016 | Pubmed ID: 27436752 Liver X Receptor β: New Player in the Regulatory Network of Thyroid Hormone and 'browning' of White Fat Adipocyte. Apr-Jun, 2016 | Pubmed ID: 27386163 Ablation of Liver X Receptors α and β Leads to Spontaneous Peripheral Squamous Cell Lung Cancer in Mice Proceedings of the National Academy of Sciences of the United States of America. 07, 2016 | Pubmed ID: 27335465 Estrogen Receptor Beta Reduces Colon Cancer Metastasis Through a Novel MiR-205 - PROX1 Mechanism Oncotarget. Jul, 2016 | Pubmed ID: 27283988 Selective Estrogen Receptor β Agonist LY500307 As a Novel Therapeutic Agent for Glioblastoma Scientific Reports. 04, 2016 | Pubmed ID: 27126081 Cyclodextrin Promotes Atherosclerosis Regression Via Macrophage Reprogramming Science Translational Medicine. Apr, 2016 | Pubmed ID: 27053774 Estrogen Signaling and Unfolded Protein Response in Breast Cancer The Journal of Steroid Biochemistry and Molecular Biology. 10, 2016 | Pubmed ID: 27045680 Soluble (pro)renin Receptor Via β-catenin Enhances Urine Concentration Capability As a Target of Liver X Receptor Proceedings of the National Academy of Sciences of the United States of America. Mar, 2016 | Pubmed ID: 26984496 Sexual Dimorphism in Circadian Physiology Is Altered in LXRα Deficient Mice PloS One. 2016 | Pubmed ID: 26938655 BRCA1 Inhibits AR-mediated Proliferation of Breast Cancer Cells Through the Activation of SIRT1 Scientific Reports. Feb, 2016 | Pubmed ID: 26902145 ERβ Decreases the Invasiveness of Triple-negative Breast Cancer Cells by Regulating Mutant P53 Oncogenic Function Oncotarget. Mar, 2016 | Pubmed ID: 26871946 Editorial The Journal of Steroid Biochemistry and Molecular Biology. Mar, 2016 | Pubmed ID: 26791250 Estrogen Receptor Beta As Target for Colorectal Cancer Prevention Cancer Letters. Mar, 2016 | Pubmed ID: 26708506 Nuclear Hormone Receptor LXRα Inhibits Adipocyte Differentiation of Mesenchymal Stem Cells with Wnt/beta-catenin Signaling Laboratory Investigation; a Journal of Technical Methods and Pathology. Feb, 2016 | Pubmed ID: 26595172 Estrogen Receptor-α Knockout Mice Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26585154 Lxr Regulates Lipid Metabolic and Visual Perception Pathways During Zebrafish Development Molecular and Cellular Endocrinology. Jan, 2016 | Pubmed ID: 26427652 Historical Overview of Nuclear Receptors The Journal of Steroid Biochemistry and Molecular Biology. Mar, 2016 | Pubmed ID: 25797032 The Bone-sparing Effects of Estrogen and WNT16 Are Independent of Each Other Proceedings of the National Academy of Sciences of the United States of America. Dec, 2015 | Pubmed ID: 26627248 Pharmacological Activation of Thyroid Hormone Receptors Elicits a Functional Conversion of White to Brown Fat Cell Reports. Nov, 2015 | Pubmed ID: 26586443 Liver X Receptor β Controls Thyroid Hormone Feedback in the Brain and Regulates Browning of Subcutaneous White Adipose Tissue Proceedings of the National Academy of Sciences of the United States of America. Nov, 2015 | Pubmed ID: 26504234 Adult Human and Mouse Ovaries Lack DDX4-expressing Functional Oogonial Stem Cells Nature Medicine. Oct, 2015 | Pubmed ID: 26444631 Identification of Proteins Highly Expressed in Uterine Fluid from Mice with Hydrometra Biochemical and Biophysical Research Communications. Oct, 2015 | Pubmed ID: 26393907 Estrogen Receptor Alpha and Beta in Health and Disease Best Practice & Research. Clinical Endocrinology & Metabolism. Aug, 2015 | Pubmed ID: 26303083 Progesterone Receptor-estrogen Receptor Crosstalk: a Novel Insight Trends in Endocrinology and Metabolism: TEM. Sep, 2015 | Pubmed ID: 26277479 The FKBP52 Cochaperone Acts in Synergy with β-Catenin to Potentiate Androgen Receptor Signaling PloS One. 2015 | Pubmed ID: 26207810 Estrogen Receptor Mutations and Functional Consequences for Breast Cancer Trends in Endocrinology and Metabolism: TEM. Sep, 2015 | Pubmed ID: 26183887 Cardiac LXRα Protects Against Pathological Cardiac Hypertrophy and Dysfunction by Enhancing Glucose Uptake and Utilization EMBO Molecular Medicine. Sep, 2015 | Pubmed ID: 26160456 Disruption of Prostaglandin E2 Receptor EP4 Impairs Urinary Concentration Via Decreasing Aquaporin 2 in Renal Collecting Ducts Proceedings of the National Academy of Sciences of the United States of America. Jul, 2015 | Pubmed ID: 26100911 Estrogen Receptor β2 Induces Hypoxia Signature of Gene Expression by Stabilizing HIF-1α in Prostate Cancer PloS One. 2015 | Pubmed ID: 26010887 Control of Gene Expression by Novel Metabolic Intermediates The Journal of Steroid Biochemistry and Molecular Biology. Sep, 2015 | Pubmed ID: 25869558 Estrogen Receptor β Exon 3-deleted Mouse: The Importance of Non-ERE Pathways in ERβ Signaling Proceedings of the National Academy of Sciences of the United States of America. Apr, 2015 | Pubmed ID: 25848008 Targeting Liver X Receptors in Cancer Therapeutics Nature Reviews. Cancer. Apr, 2015 | Pubmed ID: 25786697 Phosphorylation of Glucocorticoid Receptor Tau1c Transactivation Domain Enhances Binding to CREB Binding Protein (CBP) TAZ2 Biochemical and Biophysical Research Communications. Jan, 2015 | Pubmed ID: 25511704 Identification of Environmental Chemicals That Induce Yolk Malabsorption in Zebrafish Using Automated Image Segmentation Reproductive Toxicology (Elmsford, N.Y.). Aug, 2015 | Pubmed ID: 25462786 Estrogen Receptors in Breast Carcinogenesis and Endocrine Therapy Molecular and Cellular Endocrinology. Dec, 2015 | Pubmed ID: 25433206 Comparison of Toxicity Values Across Zebrafish Early Life Stages and Mammalian Studies: Implications for Chemical Testing Reproductive Toxicology (Elmsford, N.Y.). Aug, 2015 | Pubmed ID: 25261610 PRMT3 Regulates Hepatic Lipogenesis Through Direct Interaction with LXRα Diabetes. Jan, 2015 | Pubmed ID: 25187371 Estrogen Receptor Signaling During Vertebrate Development Biochimica Et Biophysica Acta. Feb, 2015 | Pubmed ID: 24954179 Life-long in Vivo Cell-lineage Tracing Shows That No Oogenesis Originates from Putative Germline Stem Cells in Adult Mice Proceedings of the National Academy of Sciences of the United States of America. Dec, 2014 | Pubmed ID: 25453063 A Screening Cascade to Identify ERβ Ligands Nuclear Receptor Signaling. 2014 | Pubmed ID: 25422593 Cholestenoic Acids Regulate Motor Neuron Survival Via Liver X Receptors The Journal of Clinical Investigation. Nov, 2014 | Pubmed ID: 25271621 Antiproliferative Effects and Mechanisms of Liver X Receptor Ligands in Pancreatic Ductal Adenocarcinoma Cells PloS One. 2014 | Pubmed ID: 25184494 Selectivity of Natural, Synthetic and Environmental Estrogens for Zebrafish Estrogen Receptors Toxicology and Applied Pharmacology. Oct, 2014 | Pubmed ID: 25106122 Transcriptional Regulation of the Sodium-coupled Neutral Amino Acid Transporter (SNAT2) by 17β-estradiol Proceedings of the National Academy of Sciences of the United States of America. Aug, 2014 | Pubmed ID: 25056967 Comparative Proteomic Study Reveals 17β-HSD13 As a Pathogenic Protein in Nonalcoholic Fatty Liver Disease Proceedings of the National Academy of Sciences of the United States of America. Aug, 2014 | Pubmed ID: 25028495 The Human Orphan Nuclear Receptor Tailless (TLX, NR2E1) is Druggable PloS One. 2014 | Pubmed ID: 24936658 Structural and Functional Insight into TAF1-TAF7, a Subcomplex of Transcription Factor II D Proceedings of the National Academy of Sciences of the United States of America. Jun, 2014 | Pubmed ID: 24927529 Embryonic Exposure to Sodium Arsenite Perturbs Vascular Development in Zebrafish Aquatic Toxicology (Amsterdam, Netherlands). Jul, 2014 | Pubmed ID: 24768856 Hepatic ACAT2 Knock Down Increases ABCA1 and Modifies HDL Metabolism in Mice PloS One. 2014 | Pubmed ID: 24695360 Liver X Receptor β Delays Transformation of Radial Glial Cells into Astrocytes During Mouse Cerebral Cortical Development Neurochemistry International. May, 2014 | Pubmed ID: 24662373 Sex Differences in Exercise-induced Physiological Myocardial Hypertrophy Are Modulated by Oestrogen Receptor Beta Cardiovascular Research. Jun, 2014 | Pubmed ID: 24654233 ERβ Regulates NSCLC Phenotypes by Controlling Oncogenic RAS Signaling Molecular Cancer Research : MCR. Jun, 2014 | Pubmed ID: 24618619 Halogenated Bisphenol-A Analogs Act As Obesogens in Zebrafish Larvae (Danio Rerio) Toxicological Sciences : an Official Journal of the Society of Toxicology. May, 2014 | Pubmed ID: 24591153 Structure of the Retinoid X Receptor α-liver X Receptor β (RXRα-LXRβ) Heterodimer on DNA Nature Structural & Molecular Biology. Mar, 2014 | Pubmed ID: 24561505 Estrogen Receptor Beta As a Novel Target of Androgen Receptor Action in Breast Cancer Cell Lines Breast Cancer Research : BCR. Feb, 2014 | Pubmed ID: 24552459 Farnesoid X Receptor (FXR) Gene Deficiency Impairs Urine Concentration in Mice Proceedings of the National Academy of Sciences of the United States of America. Feb, 2014 | Pubmed ID: 24464484 Differential Expression of Estrogen Receptor α, β1, and β2 in Lobular and Ductal Breast Cancer Proceedings of the National Academy of Sciences of the United States of America. Feb, 2014 | Pubmed ID: 24449868 AP2-Cre-mediated Inactivation of Estrogen Receptor Alpha Causes Hydrometra PloS One. 2014 | Pubmed ID: 24416430 The Estrogen Receptor Antagonist ICI 182,780 Can Act Both As an Agonist and an Inverse Agonist when Estrogen Receptor α AF-2 is Modified Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014 | Pubmed ID: 24395795 Action Mechanisms of Liver X Receptors Biochemical and Biophysical Research Communications. Apr, 2014 | Pubmed ID: 24300092 Co-exposure to Phytoestrogens and Bisphenol A Mimic Estrogenic Effects in an Additive Manner Toxicological Sciences : an Official Journal of the Society of Toxicology. Nov, 2013 | Pubmed ID: 24284790 Identification of Estrogen Target Genes During Zebrafish Embryonic Development Through Transcriptomic Analysis PloS One. 2013 | Pubmed ID: 24223173 Insight into the Mechanisms of Action of Estrogen Receptor β in the Breast, Prostate, Colon, and CNS Journal of Molecular Endocrinology. Dec, 2013 | Pubmed ID: 24031087 The Oxysterol-CXCR2 Axis Plays a Key Role in the Recruitment of Tumor-promoting Neutrophils The Journal of Experimental Medicine. Aug, 2013 | Pubmed ID: 23897983 Liver × Receptor Ligands Disrupt Breast Cancer Cell Proliferation Through an E2F-mediated Mechanism Breast Cancer Research : BCR. Jun, 2013 | Pubmed ID: 23809258 Meta-analysis of Toxicity and Teratogenicity of 133 Chemicals from Zebrafish Developmental Toxicity Studies Reproductive Toxicology (Elmsford, N.Y.). Nov, 2013 | Pubmed ID: 23796950 Estrogen Signalling and the Metabolic Syndrome: Targeting the Hepatic Estrogen Receptor Alpha Action PloS One. 2013 | Pubmed ID: 23451233 LXR Activation by GW3965 Alters Fat Tissue Distribution and Adipose Tissue Inflammation in Ob/ob Female Mice Journal of Lipid Research. May, 2013 | Pubmed ID: 23446231 Estrogen Receptor β Expression Induces Changes in the MicroRNA Pool in Human Colon Cancer Cells Carcinogenesis. Jul, 2013 | Pubmed ID: 23436804 Targeting Estrogen Receptor β in Microglia and T Cells to Treat Experimental Autoimmune Encephalomyelitis Proceedings of the National Academy of Sciences of the United States of America. Feb, 2013 | Pubmed ID: 23401502 Antidiabetic Actions of an Estrogen Receptor β Selective Agonist Diabetes. Jun, 2013 | Pubmed ID: 23349481 Estrogen Receptor-α in Osteocytes is Important for Trabecular Bone Formation in Male Mice Proceedings of the National Academy of Sciences of the United States of America. Feb, 2013 | Pubmed ID: 23345419 Segmentation of Zebrafish Embryonic Images Using a Geometric Atlas Deformation Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 2012 | Pubmed ID: 23366804 ERbeta1 Represses Basal Breast Cancer Epithelial to Mesenchymal Transition by Destabilizing EGFR Breast Cancer Research : BCR. 2012 | Pubmed ID: 23158001 Thyroid Hormone Receptor Agonists Reduce Serum Cholesterol Independent of the LDL Receptor Endocrinology. Dec, 2012 | Pubmed ID: 23087171 Fasting-induced FGF21 is Repressed by LXR Activation Via Recruitment of an HDAC3 Corepressor Complex in Mice Molecular Endocrinology (Baltimore, Md.). Dec, 2012 | Pubmed ID: 23073827 Estrogen Receptors β1 and β2 Have Opposing Roles in Regulating Proliferation and Bone Metastasis Genes in the Prostate Cancer Cell Line PC3 Molecular Endocrinology (Baltimore, Md.). Dec, 2012 | Pubmed ID: 23028063 Oxysterol Gradient Generation by Lymphoid Stromal Cells Guides Activated B Cell Movement During Humoral Responses Immunity. Sep, 2012 | Pubmed ID: 22999953 Liver X Receptor β Protects Dopaminergic Neurons in a Mouse Model of Parkinson Disease Proceedings of the National Academy of Sciences of the United States of America. Aug, 2012 | Pubmed ID: 22826221 Targeting PES1 for Restoring the ERα/ERβ Ratio in Breast Cancer The Journal of Clinical Investigation. Aug, 2012 | Pubmed ID: 22820293 Liver X Receptor β and Peroxisome Proliferator-activated Receptor δ Regulate Cholesterol Transport in Murine Cholangiocytes Hepatology (Baltimore, Md.). Dec, 2012 | Pubmed ID: 22729460 Anxiety in Liver X Receptor β Knockout Female Mice with Loss of Glutamic Acid Decarboxylase in Ventromedial Prefrontal Cortex Proceedings of the National Academy of Sciences of the United States of America. May, 2012 | Pubmed ID: 22529354 Knockdown of SF-1 and RNF31 Affects Components of Steroidogenesis, TGFβ, and Wnt/β-catenin Signaling in Adrenocortical Carcinoma Cells PloS One. 2012 | Pubmed ID: 22427816 The Aromatase Gene CYP19A1: Several Genetic and Functional Lines of Evidence Supporting a Role in Reading, Speech and Language Behavior Genetics. Jul, 2012 | Pubmed ID: 22426781 The Rs3743205 SNP is Important for the Regulation of the Dyslexia Candidate Gene DYX1C1 by Estrogen Receptor β and DNA Methylation Molecular Endocrinology (Baltimore, Md.). Apr, 2012 | Pubmed ID: 22383464 Rapid Insulinotropic Action of Low Doses of Bisphenol-A on Mouse and Human Islets of Langerhans: Role of Estrogen Receptor β PloS One. 2012 | Pubmed ID: 22347437 Central Diabetes Insipidus Associated with Impaired Renal Aquaporin-1 Expression in Mice Lacking Liver X Receptor β Proceedings of the National Academy of Sciences of the United States of America. Feb, 2012 | Pubmed ID: 22323586 Reduction of Dendritic Spines and Elevation of GABAergic Signaling in the Brains of Mice Treated with an Estrogen Receptor β Ligand Proceedings of the National Academy of Sciences of the United States of America. Jan, 2012 | Pubmed ID: 22307635 Uric Acid Stones in the Urinary Bladder of Aryl Hydrocarbon Receptor (AhR) Knockout Mice Proceedings of the National Academy of Sciences of the United States of America. Jan, 2012 | Pubmed ID: 22232670 Genome-wide Profiling of Liver X Receptor, Retinoid X Receptor, and Peroxisome Proliferator-activated Receptor α in Mouse Liver Reveals Extensive Sharing of Binding Sites Molecular and Cellular Biology. Feb, 2012 | Pubmed ID: 22158963 Automatic Segmentation of Time-lapse Microscopy Images Depicting a Live Dharma Embryo Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 2011 | Pubmed ID: 22256217 Estrogen Receptor β and 17β-hydroxysteroid Dehydrogenase Type 6, a Growth Regulatory Pathway That is Lost in Prostate Cancer Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22114194 Estrogen Receptors and the Metabolic Network Cell Metabolism. Sep, 2011 | Pubmed ID: 21907136 Activation of Liver X Receptor (LXR) Inhibits Receptor Activator of Nuclear Factor κB Ligand (RANKL)-induced Osteoclast Differentiation in an LXRβ-dependent Mechanism The Journal of Biological Chemistry. Sep, 2011 | Pubmed ID: 21784849 The Different Roles of ER Subtypes in Cancer Biology and Therapy Nature Reviews. Cancer. Jul, 2011 | Pubmed ID: 21779010 Developmental Toxicity Screening in Zebrafish Birth Defects Research. Part C, Embryo Today : Reviews. Jun, 2011 | Pubmed ID: 21671351 Estrogen Receptor β Induces Antiinflammatory and Antitumorigenic Networks in Colon Cancer Cells Molecular Endocrinology (Baltimore, Md.). Jun, 2011 | Pubmed ID: 21493669 Estrogen Receptor β Represses Akt Signaling in Breast Cancer Cells Via Downregulation of HER2/HER3 and Upregulation of PTEN: Implications for Tamoxifen Sensitivity Breast Cancer Research : BCR. Apr, 2011 | Pubmed ID: 21492444 Both Liver-X Receptor (LXR) Isoforms Control Energy Expenditure by Regulating Brown Adipose Tissue Activity Proceedings of the National Academy of Sciences of the United States of America. Jan, 2011 | Pubmed ID: 21173252 Quantitative Proteomics and Transcriptomics Addressing the Estrogen Receptor Subtype-mediated Effects in T47D Breast Cancer Cells Exposed to the Phytoestrogen Genistein Molecular & Cellular Proteomics : MCP. Jan, 2011 | Pubmed ID: 20884965 Estrogen Receptor Beta Decreases Survival of P53-defective Cancer Cells After DNA Damage by Impairing G₂/M Checkpoint Signaling Breast Cancer Research and Treatment. Jun, 2011 | Pubmed ID: 20623183 Does Consuming Isoflavones Reduce or Increase Breast Cancer Risk? Genome Medicine. Dec, 2010 | Pubmed ID: 21176178 Estrogen Signaling Via Estrogen Receptor {beta} The Journal of Biological Chemistry. Dec, 2010 | Pubmed ID: 20956532 Decreased Fat Storage by Lactobacillus Paracasei is Associated with Increased Levels of Angiopoietin-like 4 Protein (ANGPTL4) PloS One. Sep, 2010 | Pubmed ID: 20927337 Estrogen-dependent Gallbladder Carcinogenesis in LXRbeta-/- Female Mice Proceedings of the National Academy of Sciences of the United States of America. Aug, 2010 | Pubmed ID: 20679224 ERbeta: Recent Understanding of Estrogen Signaling Trends in Endocrinology and Metabolism: TEM. Sep, 2010 | Pubmed ID: 20646931 Liver X Receptor Beta and Thyroid Hormone Receptor Alpha in Brain Cortical Layering Proceedings of the National Academy of Sciences of the United States of America. Jul, 2010 | Pubmed ID: 20566868 Proteomics Analysis of the Estrogen Receptor Alpha Receptosome Molecular & Cellular Proteomics : MCP. Jul, 2010 | Pubmed ID: 20348541 Gonadotropin-positive Pituitary Tumors Accompanied by Ovarian Tumors in Aging Female ERbeta-/- Mice Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010 | Pubmed ID: 20308571 GPS2-dependent Corepressor/SUMO Pathways Govern Anti-inflammatory Actions of LRH-1 and LXRbeta in the Hepatic Acute Phase Response Genes & Development. Feb, 2010 | Pubmed ID: 20159957 Hes-6, an Inhibitor of Hes-1, is Regulated by 17beta-estradiol and Promotes Breast Cancer Cell Proliferation Breast Cancer Research : BCR. 2009 | Pubmed ID: 19891787 Rapid Regulation of K(ATP) Channel Activity by 17{beta}-estradiol in Pancreatic {beta}-cells Involves the Estrogen Receptor {beta} and the Atrial Natriuretic Peptide Receptor Molecular Endocrinology (Baltimore, Md.). Dec, 2009 | Pubmed ID: 19855088 Susceptibility of Pancreatic Beta Cells to Fatty Acids is Regulated by LXR/PPARalpha-dependent Stearoyl-coenzyme A Desaturase PloS One. Sep, 2009 | Pubmed ID: 19787047 Effects of Estrogen Receptor Alpha and Beta Gene Deletion on Estrogenic Induction of Progesterone Receptors in the Locus Coeruleus in Female Mice Endocrine. Aug, 2009 | Pubmed ID: 19551522 Disruption of Estrogen Receptor Signaling Enhances Intestinal Neoplasia in Apc(Min/+) Mice Carcinogenesis. Sep, 2009 | Pubmed ID: 19520794 Gene Expression in Murine Mammary Epithelial Stem Cell-like Cells Shows Similarities to Human Breast Cancer Gene Expression Breast Cancer Research : BCR. 2009 | Pubmed ID: 19426500 Functional and Genetic Analysis in Type 2 Diabetes of Liver X Receptor Alleles--a Cohort Study BMC Medical Genetics. 2009 | Pubmed ID: 19292929 E3 Ubiquitin Ligase RNF31 Cooperates with DAX-1 in Transcriptional Repression of Steroidogenesis Molecular and Cellular Biology. Apr, 2009 | Pubmed ID: 19237537 A Role for Epithelial-mesenchymal Transition in the Etiology of Benign Prostatic Hyperplasia Proceedings of the National Academy of Sciences of the United States of America. Feb, 2009 | Pubmed ID: 19196965 A Layered Mounting Method for Extended Time-Lapse Confocal Microscopy of Whole Zebrafish Embryos Sanat Upadhyay1, Leoncio Vergara2, Pranjali Shah2, Jan-Åke Gustafsson3,4, Ioannis Kakadiaris1,4, Maria Bondesson5 1Computational Biomedicine Lab, Texas Institute of Measurement Evaluation and Statistics, University of Houston, 2Institute of Biosciences and Technology, Texas A&M Health Science Center, 3Department of Biology and Biochemistry, Center for Nuclear Receptors and Cell Signaling, University of Houston, 4Department of Biosciences and Nutrition, Novum, Karolinska Institutet, 5Department of Intelligent Systems Engineering, Indiana University JoVE 60321 Developmental Biology
A Layered Mounting Method for Extended Time-Lapse Confocal Microscopy of Whole Zebrafish Embryos Sanat Upadhyay1, Leoncio Vergara2, Pranjali Shah2, Jan-Åke Gustafsson3,4, Ioannis Kakadiaris1,4, Maria Bondesson5 1Computational Biomedicine Lab, Texas Institute of Measurement Evaluation and Statistics, University of Houston, 2Institute of Biosciences and Technology, Texas A&M Health Science Center, 3Department of Biology and Biochemistry, Center for Nuclear Receptors and Cell Signaling, University of Houston, 4Department of Biosciences and Nutrition, Novum, Karolinska Institutet, 5Department of Intelligent Systems Engineering, Indiana University JoVE 60321 Developmental Biology
