Jason D. Huber Department of Neurosurgery West Virginia University Biography Publications Institution JoVE Articles Jason D. Huber has not added a biography. If you are Jason D. Huber and would like to personalize this page please email our Author Liaison for assistance. Publications Exposure to Mild Blast Forces Induces Neuropathological Effects, Neurophysiological Deficits and Biochemical Changes Molecular Brain. 11, 2018 | Pubmed ID: 30409147 Reduction of Endothelial Nitric Oxide Increases the Adhesiveness of Constitutive Endothelial Membrane ICAM-1 Through Src-Mediated Phosphorylation Frontiers in Physiology. 2017 | Pubmed ID: 29367846 A Mouse Model of Focal Vascular Injury Induces Astrocyte Reactivity, Tau Oligomers, and Aberrant Behavior Archives of Neuroscience. Apr, 2017 | Pubmed ID: 28758136 Single Low-dose Lipopolysaccharide Preconditioning: Neuroprotective Against Axonal Injury and Modulates Glial Cells Neuroimmunology and Neuroinflammation. Jan, 2017 | Pubmed ID: 28164149 Endoplasmic Reticulum Stress Modulation As a Target for Ameliorating Effects of Blast Induced Traumatic Brain Injury Journal of Neurotrauma. 09, 2017 | Pubmed ID: 28077004 Elucidating the Role of Compression Waves and Impact Duration for Generating Mild Traumatic Brain Injury in Rats Brain Injury. 2017 | Pubmed ID: 27880054 The Role for Infarct Volume As a Surrogate Measure of Functional Outcome Following Ischemic Stroke Journal of Systems and Integrative Neuroscience. Dec, 2016 | Pubmed ID: 28299202 Behavioral and Biochemical Effects of Ketamine and Dextromethorphan Relative to Its Antidepressant-like Effects in Swiss Webster Mice Neuroreport. Sep, 2016 | Pubmed ID: 27580401 Salubrinal Reduces Oxidative Stress, Neuroinflammation and Impulsive-like Behavior in a Rodent Model of Traumatic Brain Injury Brain Research. 07, 2016 | Pubmed ID: 27131989 Aneurysmal Subarachnoid Hemorrhage and Neuroinflammation: A Comprehensive Review International Journal of Molecular Sciences. Apr, 2016 | Pubmed ID: 27049383 Endoplasmic Reticulum Stress Implicated in Chronic Traumatic Encephalopathy Journal of Neurosurgery. Mar, 2016 | Pubmed ID: 26381255 Modeling Chronic Traumatic Encephalopathy: The Way Forward for Future Discovery Frontiers in Neurology. 2015 | Pubmed ID: 26579067 The Quest to Model Chronic Traumatic Encephalopathy: A Multiple Model and Injury Paradigm Experience Frontiers in Neurology. 2015 | Pubmed ID: 26539159 Traumatic Brain Injury and Epilepsy: Underlying Mechanisms Leading to Seizure Seizure. Dec, 2015 | Pubmed ID: 26519659 Amelioration of Nicotinamide Adenine Dinucleotide Phosphate-oxidase mediated Stress Reduces Cell Death After Blast-induced Traumatic Brain Injury Translational Research : the Journal of Laboratory and Clinical Medicine. Dec, 2015 | Pubmed ID: 26414010 Bryostatin Extends TPA Time Window to 6 H Following Middle Cerebral Artery Occlusion in Aged Female Rats European Journal of Pharmacology. Oct, 2015 | Pubmed ID: 26189021 Role of Microvascular Disruption in Brain Damage from Traumatic Brain Injury Comprehensive Physiology. Jul, 2015 | Pubmed ID: 26140712 Sleep Disruption and the Sequelae Associated with Traumatic Brain Injury Neuroscience and Biobehavioral Reviews. Aug, 2015 | Pubmed ID: 25956251 Bryostatin-1 Restores Blood Brain Barrier Integrity Following Blast-Induced Traumatic Brain Injury Molecular Neurobiology. Dec, 2015 | Pubmed ID: 25301233 Common Mechanisms of Alzheimer's Disease and Ischemic Stroke: the Role of Protein Kinase C in the Progression of Age-related Neurodegeneration Journal of Alzheimer's Disease : JAD. 2015 | Pubmed ID: 25114088 Sesamol: a Treatment for Diabetes-Associated Blood-Brain Barrier Dysfunction Postdoc Journal : a Journal of Postdoctoral Research and Postdoctoral Affairs. Jul, 2014 | Pubmed ID: 28781979 Metabolic Syndrome and Its Profound Effect on Prevalence of Ischemic Stroke American Medical Student Research Journal. 2014 | Pubmed ID: 27284575 A Review of Sleep Deprivation Studies Evaluating the Brain Transcriptome SpringerPlus. 2014 | Pubmed ID: 25932362 Aging, the Metabolic Syndrome, and Ischemic Stroke: Redefining the Approach for Studying the Blood-brain Barrier in a Complex Neurological Disease Advances in Pharmacology (San Diego, Calif.). 2014 | Pubmed ID: 25307225 Combination Treatment of R-tPA and an Optimized Human Apyrase Reduces Mortality Rate and Hemorrhagic Transformation 6h After Ischemic Stroke in Aged Female Rats European Journal of Pharmacology. Sep, 2014 | Pubmed ID: 24933645 Ischemic Stroke Injury is Mediated by Aberrant Cdk5 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2014 | Pubmed ID: 24920629 SN79, a Sigma Receptor Antagonist, Attenuates Methamphetamine-induced Astrogliosis Through a Blockade of OSMR/gp130 Signaling and STAT3 Phosphorylation Experimental Neurology. Apr, 2014 | Pubmed ID: 24508558 Elucidating the Severity of Preclinical Traumatic Brain Injury Models: a Role for Functional Assessment? Neurosurgery. Apr, 2014 | Pubmed ID: 24448183 C-reactive Protein and Long-term Ischemic Stroke Prognosis Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. Apr, 2014 | Pubmed ID: 24211144 Bryostatin Improves Survival and Reduces Ischemic Brain Injury in Aged Rats After Acute Ischemic Stroke Stroke. Dec, 2013 | Pubmed ID: 24172582 Modeling Clinically Relevant Blast Parameters Based on Scaling Principles Produces Functional & Histological Deficits in Rats Experimental Neurology. Oct, 2013 | Pubmed ID: 23876514 SN79, a Sigma Receptor Ligand, Blocks Methamphetamine-induced Microglial Activation and Cytokine Upregulation Experimental Neurology. Sep, 2013 | Pubmed ID: 23631864 Neuroprotection for Ischemic Stroke: Moving Past Shortcomings and Identifying Promising Directions International Journal of Molecular Sciences. Jan, 2013 | Pubmed ID: 23344061 The Science of Cerebral Ischemia and the Quest for Neuroprotection: Navigating Past Failure to Future Success Journal of Neurosurgery. May, 2013 | Pubmed ID: 23331000 Age and the Metabolic Syndrome As Risk Factors for Ischemic Stroke: Improving Preclinical Models of Ischemic Stroke The Yale Journal of Biology and Medicine. Dec, 2012 | Pubmed ID: 23239952 Effects of Aging on Behavioral Assessment Performance: Implications for Clinically Relevant Models of Neurological Disease Journal of Neurosurgery. Sep, 2012 | Pubmed ID: 22746378 Worsened Outcome from Middle Cerebral Artery Occlusion in Aged Rats Receiving 17β-estradiol Endocrinology. Jul, 2012 | Pubmed ID: 22581460 The Transcriptome of Cerebral Ischemia Brain Research Bulletin. Jul, 2012 | Pubmed ID: 22381515 Potential Age-dependent Effects of Estrogen on Neural Injury The American Journal of Pathology. Jun, 2011 | Pubmed ID: 21641373 Targeting the Neurovascular Unit for Treatment of Neurological Disorders Pharmacology & Therapeutics. Jun, 2011 | Pubmed ID: 21172386 Sigma (σ) Receptor Ligand, AC927 (N-phenethylpiperidine Oxalate), Attenuates Methamphetamine-induced Hyperthermia and Serotonin Damage in Mice Pharmacology, Biochemistry, and Behavior. Mar, 2011 | Pubmed ID: 21130800 NOX2 Inhibition with Apocynin Worsens Stroke Outcome in Aged Rats Brain Research. Oct, 2009 | Pubmed ID: 19635468 Administration of Sesamol Improved Blood-brain Barrier Function in Streptozotocin-induced Diabetic Rats Experimental Brain Research. Jul, 2009 | Pubmed ID: 19565232 Plasminogen Activator Inhibitor Type 1 Derived Peptide, EEIIMD, Diminishes Cortical Infarct but Fails to Improve Neurological Function in Aged Rats Following Middle Cerebral Artery Occlusion Brain Research. Jul, 2009 | Pubmed ID: 19465008 Early Disruptions of the Blood-brain Barrier May Contribute to Exacerbated Neuronal Damage and Prolonged Functional Recovery Following Stroke in Aged Rats Neurobiology of Aging. May, 2008 | Pubmed ID: 17241702 Streptozotocin-induced Diabetes Progressively Increases Blood-brain Barrier Permeability in Specific Brain Regions in Rats American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2006 | Pubmed ID: 16951046 Chronic Inflammatory Pain Leads to Increased Blood-brain Barrier Permeability and Tight Junction Protein Alterations American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2005 | Pubmed ID: 15792985 Low-Intensity Blast Wave Model for Preclinical Assessment of Closed-Head Mild Traumatic Brain Injury bei Nagetieren Aric F. Logsdon*1,2, Brandon P. Lucke-Wold*3, Ryan C. Turner*4, Sean M. Collins5, Evan L. Reeder5, Jason D. Huber4, Charles L. Rosen6, Matthew J. Robson*5, Florian Plattner*7 1Geriatrics Research Education and Clinical Center, Veterans Affairs, 2Division of Gerontology and Geriatric Medicine, University of Washington, 3Department of Neurosurgery, University of Florida, 4Department of Neurosurgery, West Virginia University, 5Division of Pharmaceutical Sciences, University of Cincinnati, 6Central Illinois Neuro Health Sciences, Bloomington, IL, 7Neuro-research, Dallas, TX JoVE 61244 Neuroscience
Low-Intensity Blast Wave Model for Preclinical Assessment of Closed-Head Mild Traumatic Brain Injury bei Nagetieren Aric F. Logsdon*1,2, Brandon P. Lucke-Wold*3, Ryan C. Turner*4, Sean M. Collins5, Evan L. Reeder5, Jason D. Huber4, Charles L. Rosen6, Matthew J. Robson*5, Florian Plattner*7 1Geriatrics Research Education and Clinical Center, Veterans Affairs, 2Division of Gerontology and Geriatric Medicine, University of Washington, 3Department of Neurosurgery, University of Florida, 4Department of Neurosurgery, West Virginia University, 5Division of Pharmaceutical Sciences, University of Cincinnati, 6Central Illinois Neuro Health Sciences, Bloomington, IL, 7Neuro-research, Dallas, TX JoVE 61244 Neuroscience
