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Jason M. Conley

Department of Medicinal Chemistry and Molecular Pharmacology

Purdue University

Biography
Publications
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Publications

Development of a High-throughput Screening Paradigm for the Discovery of Small-molecule Modulators of Adenylyl Cyclase: Identification of an Adenylyl Cyclase 2 Inhibitor
The Journal of Pharmacology and Experimental Therapeutics. Nov, 2013 | Pubmed ID: 24008337
Differential Effects of AGS3 Expression on D(2L) Dopamine Receptor-mediated Adenylyl Cyclase Signaling
Cellular and Molecular Neurobiology. May, 2013 | Pubmed ID: 23504261
Bimolecular Fluorescence Complementation Analysis of G Protein-coupled Receptor Dimerization in Living Cells
Methods in Enzymology. 2013 | Pubmed ID: 23351744
Identification of a 2-phenyl-substituted Octahydrobenzo[f]quinoline As a Dopamine D₃ Receptor-selective Full Agonist Ligand
Bioorganic & Medicinal Chemistry. Nov, 2012 | Pubmed ID: 23018094
A Point Mutation to Galphai Selectively Blocks GoLoco Motif Binding: Direct Evidence for Galpha.GoLoco Complexes in Mitotic Spindle Dynamics
The Journal of Biological Chemistry. Dec, 2008 | Pubmed ID: 18984596

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications

Jason M. Conley¹, Tarsis F. Brust¹, Ruqiang Xu¹, Kevin D. Burris², Val J. Watts¹

¹Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, ²Quantitative Biology, Eli Lilly and Company

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