Jay Unruh

Publications

• Tumor-initiating Stem Cell Shapes Its Microenvironment into an Immunosuppressive Barrier and Pro-tumorigenic Niche
  Cell Reports. Sep, 2021  |   Pubmed ID: 34496236
• Multiple Roles for PARP1 in ALC1-dependent Nucleosome Remodeling
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2021  |   Pubmed ID: 34465625
• Proteome Plasticity in Response to Persistent Environmental Change
  Molecular Cell. 08, 2021  |   Pubmed ID: 34293321
• Redistribution of Centrosomal Proteins by Centromeres and Polo Kinase Controls Partial Nuclear Envelope Breakdown in Fission Yeast
  Molecular Biology of the Cell. 08, 2021  |   Pubmed ID: 34133218
• A Role for the Cockayne Syndrome B (CSB)-Elongin Ubiquitin Ligase Complex in Signal-dependent RNA Polymerase II Transcription
  The Journal of Biological Chemistry. 07, 2021  |   Pubmed ID: 34116057
• Super-resolution Microscopy-based Bimolecular Fluorescence Complementation to Study Protein Complex Assembly and Co-localization
  Bio-protocol. Feb, 2020  |   Pubmed ID: 33654748
• Driving Integrative Structural Modeling with Serial Capture Affinity Purification
  Proceedings of the National Academy of Sciences of the United States of America. 12, 2020  |   Pubmed ID: 33257578
• Orderly Assembly Underpinning Built-in Asymmetry in the Yeast Centrosome Duplication Cycle Requires Cyclin-dependent Kinase
  ELife. 08, 2020  |   Pubmed ID: 32851976
• β-Catenin and Associated Proteins Regulate Lineage Differentiation in Ground State Mouse Embryonic Stem Cells
  Stem Cell Reports. 09, 2020  |   Pubmed ID: 32822591
• Chromosome and Autosomal Recombination Are Differentially Sensitive to Disruptions in SC Maintenance
  Proceedings of the National Academy of Sciences of the United States of America. 10, 2019  |   Pubmed ID: 31570610
• Amyloid-like Assembly Activates a Phosphatase in the Developing Drosophila Embryo
  Cell. 09, 2019  |   Pubmed ID: 31491385
• PCP and Wnt Pathway Components Act in Parallel During Zebrafish Mechanosensory Hair Cell Orientation
  Nature Communications. 09, 2019  |   Pubmed ID: 31488837
• Superresolution Microscopy Reveals Linkages Between Ribosomal DNA on Heterologous Chromosomes
  The Journal of Cell Biology. 08, 2019  |   Pubmed ID: 31270138
• The Stoichiometry of the Outer Kinetochore is Modulated by Microtubule-proximal Regulatory Factors
  The Journal of Cell Biology. 07, 2019  |   Pubmed ID: 31118239
• Dopamine Receptor Antagonists As Potential Therapeutic Agents for ADPKD
  PloS One. 2019  |   Pubmed ID: 31059522
• Yeast Centrosome Components Form a Noncanonical LINC Complex at the Nuclear Envelope Insertion Site
  The Journal of Cell Biology. 05, 2019  |   Pubmed ID: 30862629
• Imaging-based Assays for Investigating Functions of the RNA Polymerase II Elongation Factor Elongin and the Elongin Ubiquitin Ligase
  Methods (San Diego, Calif.). Feb, 2019  |   Pubmed ID: 30794906
• Distribution of Proteins at the Inner Nuclear Membrane Is Regulated by the Asi1 E3 Ligase in
  Genetics. 04, 2019  |   Pubmed ID: 30709848
• N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells
  Cell Reports. 01, 2019  |   Pubmed ID: 30650358
• Functional Analysis of the Yeast LINC Complex Using Fluctuation Spectroscopy and Super-Resolution Imaging
  Methods in Molecular Biology (Clifton, N.J.). 2018  |   Pubmed ID: 30141044
• Combined Expansion Microscopy with Structured Illumination Microscopy for Analyzing Protein Complexes
  Nature Protocols. 08, 2018  |   Pubmed ID: 30072723
• Quantifying Nucleation In Vivo Reveals the Physical Basis of Prion-like Phase Behavior
  Molecular Cell. 07, 2018  |   Pubmed ID: 29979963
• The Budding Yeast RSC Complex Maintains Ploidy by Promoting Spindle Pole Body Insertion
  The Journal of Cell Biology. 07, 2018  |   Pubmed ID: 29875260
• Integrative Structure and Functional Anatomy of a Nuclear Pore Complex
  Nature. 03, 2018  |   Pubmed ID: 29539637
• Structural Plasticity of the Living Kinetochore
  The Journal of Cell Biology. 11, 2017  |   Pubmed ID: 28939613
• HOXA1 and TALE Proteins Display Cross-regulatory Interactions and Form a Combinatorial Binding Code on HOXA1 Targets
  Genome Research. 09, 2017  |   Pubmed ID: 28784834
• Superresolution Expansion Microscopy Reveals the Three-dimensional Organization of the Synaptonemal Complex
  Proceedings of the National Academy of Sciences of the United States of America. 08, 2017  |   Pubmed ID: 28760978
• Ribosomal DNA Copy Number Loss and Sequence Variation in Cancer
  PLoS Genetics. Jun, 2017  |   Pubmed ID: 28640831
• Molecular Model of Fission Yeast Centrosome Assembly Determined by Superresolution Imaging
  The Journal of Cell Biology. 08, 2017  |   Pubmed ID: 28619713
• Dynamic Regulation of Nanog and Stem Cell-signaling Pathways by Hoxa1 During Early Neuro-ectodermal Differentiation of ES Cells
  Proceedings of the National Academy of Sciences of the United States of America. 06, 2017  |   Pubmed ID: 28584089
• Analysis of Membrane Proteins Localizing to the Inner Nuclear Envelope in Living Cells
  The Journal of Cell Biology. Nov, 2016  |   Pubmed ID: 27831485
• A Putative Biochemical Engram of Long-Term Memory
  Current Biology : CB. 12, 2016  |   Pubmed ID: 27818176
• WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage
  PloS One. 2016  |   Pubmed ID: 27248496
• Molecular Basis of Orb2 Amyloidogenesis and Blockade of Memory Consolidation
  PLoS Biology. Jan, 2016  |   Pubmed ID: 26812143
• Intracellular Chloride Concentration of the Mouse Vomeronasal Neuron
  BMC Neuroscience. Dec, 2015  |   Pubmed ID: 26667019
• Karyotyping Human and Mouse Cells Using Probes from Single-sorted Chromosomes and Open Source Software
  BioTechniques. Dec, 2015  |   Pubmed ID: 26651513
• Amyloidogenic Oligomerization Transforms Drosophila Orb2 from a Translation Repressor to an Activator
  Cell. Dec, 2015  |   Pubmed ID: 26638074
• Mitotic Transcriptional Activation: Clearance of Actively Engaged Pol II Via Transcriptional Elongation Control in Mitosis
  Molecular Cell. Nov, 2015  |   Pubmed ID: 26527278
• Sec66-Dependent Regulation of Yeast Spindle-Pole Body Duplication Through Pom152
  Genetics. Dec, 2015  |   Pubmed ID: 26510791
• Vilya, a Component of the Recombination Nodule, is Required for Meiotic Double-strand Break Formation in Drosophila
  ELife. Oct, 2015  |   Pubmed ID: 26452093
• Structured Illumination with Particle Averaging Reveals Novel Roles for Yeast Centrosome Components During Duplication
  ELife. Sep, 2015  |   Pubmed ID: 26371506
• Analysis of Dynamic Changes in Retinoid-induced Transcription and Epigenetic Profiles of Murine Hox Clusters in ES Cells
  Genome Research. Aug, 2015  |   Pubmed ID: 26025802
• Imaging Methodologies for Systems Biology
  Cell Adhesion & Migration. 2014  |   Pubmed ID: 25482526
• Organelle-based Aggregation and Retention of Damaged Proteins in Asymmetrically Dividing Cells
  Cell. Oct, 2014  |   Pubmed ID: 25417105
• The Membrane-associated Proteins FCHo and SGIP Are Allosteric Activators of the AP2 Clathrin Adaptor Complex
  ELife. Oct, 2014  |   Pubmed ID: 25303366
• Corolla is a Novel Protein That Contributes to the Architecture of the Synaptonemal Complex of Drosophila
  Genetics. Sep, 2014  |   Pubmed ID: 24913682
• The SUN Protein Mps3 Controls Ndc1 Distribution and Function on the Nuclear Membrane
  The Journal of Cell Biology. Feb, 2014  |   Pubmed ID: 24515347
• Cohesion Promotes Nucleolar Structure and Function
  Molecular Biology of the Cell. Feb, 2014  |   Pubmed ID: 24307683
• Independence of Symmetry Breaking on Bem1-mediated Autocatalytic Activation of Cdc42
  The Journal of Cell Biology. Sep, 2013  |   Pubmed ID: 24062340
• Binding of Drosophila Polo Kinase to Its Regulator Matrimony is Noncanonical and Involves Two Separate Functional Domains
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2013  |   Pubmed ID: 23479640
• Sequential Actin-based Pushing Forces Drive Meiosis I Chromosome Migration and Symmetry Breaking in Oocytes
  The Journal of Cell Biology. Mar, 2013  |   Pubmed ID: 23439682
• Quality Control: Putting Protein Aggregates in a Bind
  Current Biology : CB. Jan, 2013  |   Pubmed ID: 23347944
• Non-uniform Membrane Diffusion Enables Steady-state Cell Polarization Via Vesicular Trafficking
  Nature Communications. Jan, 2013  |   Pubmed ID: 23340420
• Cell-cycle-coupled Structural Oscillation of Centromeric Nucleosomes in Yeast
  Cell. Jul, 2012  |   Pubmed ID: 22817893
• Cohesin Proteins Promote Ribosomal RNA Production and Protein Translation in Yeast and Human Cells
  PLoS Genetics. 2012  |   Pubmed ID: 22719263
• Actin Depolymerization Drives Actomyosin Ring Contraction During Budding Yeast Cytokinesis
  Developmental Cell. Jun, 2012  |   Pubmed ID: 22698284
• Acetylation of the SUN Protein Mps3 by Eco1 Regulates Its Function in Nuclear Organization
  Molecular Biology of the Cell. Jul, 2012  |   Pubmed ID: 22593213
• The Arp2/3 Complex is Required for Lamellipodia Extension and Directional Fibroblast Cell Migration
  The Journal of Cell Biology. Apr, 2012  |   Pubmed ID: 22492726
• Flippase-mediated Phospholipid Asymmetry Promotes Fast Cdc42 Recycling in Dynamic Maintenance of Cell polarity
  Nature Cell Biology. Feb, 2012  |   Pubmed ID: 22344035
• Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory
  Cell. Feb, 2012  |   Pubmed ID: 22284910
• The SUN Protein Mps3 is Required for Spindle Pole Body Insertion into the Nuclear Membrane and Nuclear Envelope Homeostasis
  PLoS Genetics. Nov, 2011  |   Pubmed ID: 22125491
• Motility and Segregation of Hsp104-associated Protein Aggregates in Budding Yeast
  Cell. Nov, 2011  |   Pubmed ID: 22118470
• Dynamic Maintenance of Asymmetric Meiotic Spindle Position Through Arp2/3-complex-driven Cytoplasmic Streaming in Mouse Oocytes
  Nature Cell Biology. Aug, 2011  |   Pubmed ID: 21874009
• Fluorescence Fluctuation Spectroscopy and Imaging Methods for Examination of Dynamic Protein Interactions in Yeast
  Methods in Molecular Biology (Clifton, N.J.). 2011  |   Pubmed ID: 21863494
• Gamma-tubulin is Required for Bipolar Spindle Assembly and for Proper Kinetochore Microtubule Attachments During Prometaphase I in Drosophila Oocytes
  PLoS Genetics. Aug, 2011  |   Pubmed ID: 21852952
• BAC Modification Through Serial or Simultaneous Use of CRE/Lox Technology
  Journal of Biomedicine & Biotechnology. 2011  |   Pubmed ID: 21197414